Strain Name:
C57BL/6J-MtgxR5942Btlr
Stock Number:
044134-MU
Citation ID:
RRID:MMRRC_044134-MU
Other Names:
R5942 (G1)
Major Collection:

Gene Information

Ptx3
Name: pentraxin related gene
Synonyms: pentraxin 3, TSG-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19288
HGNC: HGNC:9692
Homologene: 7500
Enc1
Name: ectodermal-neural cortex 1
Synonyms: PIG10, Nrpb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13803
VEGA: 13
HGNC: HGNC:3345
Homologene: 2694
Sigmar1
Name: sigma non-opioid intracellular receptor 1
Synonyms: Sig1R, mSigmaR1, Oprs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18391
HGNC: HGNC:8157
Homologene: 39965
Mga
Name: MAX gene associated
Synonyms: Mga, C130042M01Rik, D030062C11Rik, Mad5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Tns3
Name: tensin 3
Synonyms: Tens1, TEM6, F830010I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319939
Homologene: 49713
Pecam1
Name: platelet/endothelial cell adhesion molecule 1
Synonyms: PECAM-1, Cd31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18613
HGNC: HGNC:8823
Homologene: 47925
Tnrc6a
Name: trinucleotide repeat containing 6a
Synonyms: 3110054G10Rik, D130023A07Rik, 2010321I05Rik, CAGH26, Tnrc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233833
Homologene: 41399
Mgmt
Name: O-6-methylguanine-DNA methyltransferase
Synonyms: AGT, Agat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17314
HGNC: HGNC:7059
Homologene: 31089
Ezh2
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: Enx-1, Enx1h, KMT6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14056
HGNC: HGNC:3527
Homologene: 37926
Ncaph
Name: non-SMC condensin I complex, subunit H
Synonyms: A730011O11Rik, Brrn1, HCAP-H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215387
HGNC: HGNC:1112
Homologene: 133986
Cep170
Name: centrosomal protein 170
Synonyms: A330004A13Rik, 4933426L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545389
Homologene: 22844
Ufl1
Name: UFM1 specific ligase 1
Synonyms: Rcad, Maxer, 1810074P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67490
Homologene: 9093
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: 5430414H02Rik, E330005K07Rik, peroxisome biogenesis factor 1, ZWS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Wbp1l
Name: WW domain binding protein 1 like
Synonyms: D19Wsu162e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226178
Homologene: 9839
Gm14393
Name: predicted gene 14393
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 664987
Wdr62
Name: WD repeat domain 62
Synonyms: 2310038K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233064
Homologene: 15927
Nt5c3
Name: 5'-nucleotidase, cytosolic III
Synonyms: Umph-1, 2610206B05Rik, cN-III, PSN1, p36, lupin, PN-I, 1600024P05Rik, PN-1, Umph1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107569
Homologene: 9534
Tfrc
Name: transferrin receptor
Synonyms: E430033M20Rik, 2610028K12Rik, p90, TfR1, Mtvr1, Mtvr-1, CD71, Trfr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22042
Homologene: 2429
Wdr25
Name: WD repeat domain 25
Synonyms: B930090D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 212198
VEGA: 12
Homologene: 56993
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: Fam82a2, 1200015F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67809
Homologene: 34926
Man2a1
Name: mannosidase 2, alpha 1
Synonyms: Mana2, Map-2, Mana-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17158
HGNC: HGNC:6824
Homologene: 1777
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: b2b414Clo, 4432416O06Rik, m407Asp, DHC2, DHC1b, D330044F14Rik, Dnchc2, D030010H02Rik, m152Asp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Morc2a
Name: microrchidia 2A
Synonyms: Zcwcc1, 8430403M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74522
Homologene: 8966
Glt1d1
Name: glycosyltransferase 1 domain containing 1
Synonyms: 5730455A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319804
Homologene: 16965
Enpp1
Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms: Pca-1, 4833416E15Rik, twy, Npps, PC-1, Ly-41, NPP1, E-NPP1, CD203c, Pca, Pdnp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18605
HGNC: HGNC:3356
Homologene: 38151
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: F630004O05Rik, D030022P06Rik, B930091H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Ttn
Name: titin
Synonyms: 2310057K23Rik, connectin, D830007G01Rik, D330041I19Rik, L56, shru, 1100001C23Rik, 2310036G12Rik, mdm, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Myo1g
Name: myosin IG
Synonyms: E430002D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246177
Homologene: 27996
Actrt3
Name: actin related protein T3
Synonyms: Arpm1, 1700119I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76652
Homologene: 13038
Hc
Name: hemolytic complement
Synonyms: Hfib2, C5a, C5, He
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Pcdhb5
Name: protocadherin beta 5
Synonyms: PcdhbE, Pcdhb4A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Accs
Name: 1-aminocyclopropane-1-carboxylate synthase (non-functional)
Synonyms: 2610203E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329470
Homologene: 75335
Zfp352
Name: zinc finger protein 352
Synonyms: 2czf48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 236537
Homologene: 45160
Pcdha1
Name: protocadherin alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 116731
HGNC: HGNC:8663
Homologene: 75093
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: CLR16.2, D230007K08Rik, Caterpiller 16.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268857
Homologene: 18720
Vmn1r231
Name: vomeronasal 1 receptor 231
Synonyms: V1re7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171230
Lamp1
Name: lysosomal-associated membrane protein 1
Synonyms: Perk, CD107a, Lamp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16783
HGNC: HGNC:6499
Homologene: 4061
Parp9
Name: poly (ADP-ribose) polymerase family, member 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 80285
Homologene: 12720
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74521
Homologene: 12571
Klhdc7b
Name: kelch domain containing 7B
Synonyms: EG546648
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 546648
Homologene: 34707
Olfr1098
Name: olfactory receptor 1098
Synonyms: MOR206-1, GA_x6K02T2Q125-48410458-48409511
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258842
Homologene: 37005
Psmc4
Name: proteasome (prosome, macropain) 26S subunit, ATPase, 4
Synonyms: CAR interacting protein 21, MIP224, CIP21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23996
HGNC: HGNC:9551
Homologene: 4744
Adamts18
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
Synonyms: E130314N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 208936
Homologene: 65241
Cttnbp2
Name: cortactin binding protein 2
Synonyms: 4732477G22Rik, 9130022E09Rik, 3010022N24Rik, Cortbp2, ORF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30785
Homologene: 14125
Olfr1170
Name: olfactory receptor 1170
Synonyms: MOR174-12, GA_x6K02T2Q125-49709783-49708833
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258525
Homologene: 138307
Has2
Name: hyaluronan synthase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15117
HGNC: HGNC:4819
Homologene: 3892
Sec16b
Name: SEC16 homolog B (S. cerevisiae)
Synonyms: Lztr2, Rgpr-p117, Rgpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 89867
Homologene: 13227
Fut10
Name: fucosyltransferase 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 171167
Homologene: 32790
Rimbp3
Name: RIMS binding protein 3
Synonyms: LOC239731, RIM-BP3, LOC385766
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239731
Homologene: 77940
Fam189a2
Name: family with sequence similarity 189, member A2
Synonyms: LOC381217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381217
VEGA: 19
Homologene: 3540
Parp14
Name: poly (ADP-ribose) polymerase family, member 14
Synonyms: CoaSt6, 1600029O10Rik, collaborator of Stat6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 547253
Homologene: 19697
Kndc1
Name: kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms: B830014K08Rik, 2410012C07Rik, very-kind, VKIND
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76484
Homologene: 45138
Parp8
Name: poly (ADP-ribose) polymerase family, member 8
Synonyms: D13Ertd275e, 2810430O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 52552
VEGA: 13
Homologene: 11621
Abcc10
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Synonyms: Mrp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224814
HGNC: HGNC:52
Homologene: 58616
Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
Synonyms: Cyp15a1, testosterone 15alpha-hydroxylase, D7Ucla4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13086
Homologene: 85917
Hook2
Name: hook microtubule tethering protein 2
Synonyms: A630054I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170833
Homologene: 8332
Ccr8
Name: chemokine (C-C motif) receptor 8
Synonyms: Cmkbr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12776
VEGA: 9
HGNC: HGNC:1609
Homologene: 21080
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239546
VEGA: 15
Homologene: 27805
Olfr1255
Name: olfactory receptor 1255
Synonyms: GA_x6K02T2Q125-51257221-51258135, MOR232-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258979
Homologene: 82298
Gpr156
Name: G protein-coupled receptor 156
Synonyms: Gababl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239845
VEGA: 16
Homologene: 17683
Olfr194
Name: olfactory receptor 194
Synonyms: GA_x54KRFPKG5P-55348161-55347241, MOR182-13, MOR182-7P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 433031
Homologene: 122781
Rnase10
Name: ribonuclease, RNase A family, 10 (non-active)
Synonyms: 4930474F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75019
VEGA: 14
Homologene: 19166
Phf11
Name: PHD finger protein 11
Synonyms: Phf11-ps, Gm6904
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 628693
VEGA: 14
Yif1a
Name: Yip1 interacting factor homolog A (S. cerevisiae)
Synonyms: 54TM, Yif1p, 5330422J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68090
VEGA: 19
Homologene: 56295
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 157,531,350 bp
  • T to A, chromosome 1 at 176,756,419 bp
  • A to T, chromosome 2 at 35,028,125 bp
  • A to T, chromosome 2 at 76,750,161 bp
  • T to C, chromosome 2 at 86,923,406 bp
  • A to C, chromosome 2 at 88,224,572 bp
  • G to T, chromosome 2 at 89,816,340 bp
  • A to T, chromosome 2 at 93,836,047 bp
  • G to A, chromosome 2 at 119,147,577 bp
  • A to G, chromosome 2 at 119,946,959 bp
  • C to A, chromosome 2 at 127,116,688 bp
  • G to A, chromosome 2 at 175,061,896 bp
  • T to A, chromosome 3 at 30,598,664 bp
  • T to G, chromosome 3 at 66,220,063 bp
  • T to C, chromosome 4 at 25,250,619 bp
  • T to C, chromosome 4 at 41,741,159 bp
  • A to T, chromosome 4 at 90,225,070 bp
  • A to G, chromosome 5 at 3,610,277 bp
  • A to T, chromosome 5 at 127,644,470 bp
  • T to A, chromosome 6 at 18,448,440 bp
  • T to C, chromosome 6 at 47,577,582 bp
  • A to T, chromosome 6 at 56,897,854 bp
  • A to T, chromosome 7 at 26,310,704 bp
  • C to T, chromosome 7 at 28,047,055 bp
  • G to A, chromosome 7 at 30,243,079 bp
  • A to G, chromosome 7 at 123,186,665 bp
  • A to G, chromosome 7 at 127,538,008 bp
  • T to A, chromosome 7 at 137,121,490 bp
  • T to C, chromosome 7 at 139,936,879 bp
  • T to C, chromosome 8 at 13,173,941 bp
  • A to G, chromosome 8 at 31,201,457 bp
  • C to T, chromosome 8 at 84,994,780 bp
  • T to C, chromosome 8 at 113,777,748 bp
  • A to T, chromosome 9 at 7,117,466 bp
  • G to T, chromosome 9 at 120,094,706 bp
  • C to A, chromosome 10 at 24,676,068 bp
  • C to A, chromosome 11 at 3,679,936 bp
  • A to G, chromosome 11 at 6,514,888 bp
  • A to T, chromosome 11 at 8,435,860 bp
  • G to T, chromosome 11 at 106,661,983 bp
  • T to A, chromosome 12 at 103,587,447 bp
  • A to G, chromosome 12 at 108,898,466 bp
  • G to A, chromosome 13 at 97,246,379 bp
  • G to T, chromosome 13 at 116,869,433 bp
  • A to T, chromosome 14 at 51,009,278 bp
  • G to A, chromosome 14 at 59,260,144 bp
  • T to A, chromosome 15 at 56,667,796 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • A to C, chromosome 15 at 89,387,431 bp
  • A to T, chromosome 16 at 3,949,429 bp
  • A to G, chromosome 16 at 17,211,888 bp
  • A to G, chromosome 16 at 32,626,715 bp
  • C to A, chromosome 16 at 35,839,367 bp
  • A to G, chromosome 16 at 35,971,889 bp
  • C to T, chromosome 16 at 38,004,902 bp
  • A to T, chromosome 16 at 59,119,676 bp
  • T to A, chromosome 17 at 20,890,155 bp
  • C to T, chromosome 17 at 46,312,407 bp
  • A to G, chromosome 17 at 64,625,380 bp
  • T to A, chromosome 18 at 36,930,391 bp
  • C to T, chromosome 18 at 37,320,785 bp
  • C to T, chromosome 19 at 5,091,641 bp
  • A to G, chromosome 19 at 23,986,470 bp
  • C to A, chromosome 19 at 46,654,430 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5942 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044134-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.