Strain Name:
C57BL/6J-MtgxR5944Btlr/Mmmh
Stock Number:
044136-MU
Citation ID:
RRID:MMRRC_044136-MU
Other Names:
R5944 (G1)
Major Collection:

Gene Information

Bcar3
Name: breast cancer anti-estrogen resistance 3
Synonyms: AND-34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 29815
HGNC: HGNC:973
Homologene: 31181
Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: SWAP2, Sfrs16, Srsf16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53609
Homologene: 134306
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66860
Homologene: 18946
Srsf11
Name: serine and arginine-rich splicing factor 11
Synonyms: 0610009J05Rik, 2610019N13Rik, Sfrs11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69207
Homologene: 36164
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: P140SRA-1, Shyc, pl-1, l(7)1Rl, Sra-1, E030028J09Rik, l7Rl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20430
Homologene: 22628
Eml4
Name: echinoderm microtubule associated protein like 4
Synonyms: 4930443C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78798
VEGA: 17
HGNC: HGNC:1316
Homologene: 56841
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: 4933425K22Rik, Gtar, A130069E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81702
Homologene: 82403
Sec24d
Name: Sec24 related gene family, member D (S. cerevisiae)
Synonyms: 2310020L09Rik, LOC383951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69608
Homologene: 40986
Papola
Name: poly (A) polymerase alpha
Synonyms: Plap, PapIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18789
Homologene: 23389
Stat3
Name: signal transducer and activator of transcription 3
Synonyms: Aprf, 1110034C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20848
Homologene: 7960
Serpini1
Name: serine (or cysteine) peptidase inhibitor, clade I, member 1
Synonyms: Neuroserpin, PI12, Spi17, Ns
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20713
HGNC: HGNC:8943
Homologene: 21045
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17847
Homologene: 40978
Dcaf13
Name: DDB1 and CUL4 associated factor 13
Synonyms: LOC223499, Wdsof1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223499
Homologene: 6430
Vars
Name: valyl-tRNA synthetase
Synonyms: G7a, D17H6S56E, Bat-6, Bat6, Vars2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22321
Homologene: 4587
Gm7964
Name: predicted gene 7964
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 666170
Arsg
Name: arylsulfatase G
Synonyms: 6330406P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74008
Homologene: 8978
Hspa9
Name: heat shock protein 9
Synonyms: mortalin, Hsp74a, Hsp74, Hsc74, PBP74, GRP75, mthsp70, mot-2, Hspa9a, C3H-specific antigen, CSA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 15526
HGNC: HGNC:5244
Homologene: 39452
Sigirr
Name: single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Synonyms: Sigirr, Tir8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 24058
Homologene: 36399
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Srgap3
Name: SLIT-ROBO Rho GTPase activating protein 3
Synonyms: Arhgap14, D130026O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 259302
Homologene: 56686
Stat4
Name: signal transducer and activator of transcription 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20849
Homologene: 20679
Lmntd1
Name: lamin tail domain containing 1
Synonyms: Lmna-rs1, 4933403M22Rik, Ifltd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74071
Homologene: 69453
Slc7a4
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224022
Homologene: 20883
Olfr1442
Name: olfactory receptor 1442
Synonyms: GA_x6K02T2RE5P-3000589-3001527, MOR202-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258692
Homologene: 138315
Slc29a4
Name: solute carrier family 29 (nucleoside transporters), member 4
Synonyms: ENT4, mPMAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243328
Homologene: 71345
Wiz
Name: widely-interspaced zinc finger motifs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22404
Homologene: 7997
Gm5581
Name: predicted gene 5581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Cenpj
Name: centromere protein J
Synonyms: 4932437H03Rik, Sas4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219103
Homologene: 10204
Olfr694
Name: olfactory receptor 694
Synonyms: GA_x6K02T2PBJ9-9067220-9066273, MOR283-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258444
Homologene: 79345
Fap
Name: fibroblast activation protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14089
HGNC: HGNC:3590
Homologene: 48282
Ifi202b
Name: interferon activated gene 202B
Synonyms: p202
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26388
Frs3
Name: fibroblast growth factor receptor substrate 3
Synonyms: SNT2, Frs2beta, 4930417B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 107971
Homologene: 4845
Gpc5
Name: glypican 5
Synonyms: A230034F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 103978
HGNC: HGNC:4453
Homologene: 3285
Fdxr
Name: ferredoxin reductase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14149
HGNC: HGNC:3642
Homologene: 3033
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627576
Homologene: 115024
Krt36
Name: keratin 36
Synonyms: HRa-1, Krt1-22, keratin 5, Krt1-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239546
VEGA: 15
Homologene: 27805
Spatc1
Name: spermatogenesis and centriole associated 1
Synonyms: 1700084J23Rik, speriolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74281
VEGA: 15
Homologene: 129861
Apol7b
Name: apolipoprotein L 7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 278679
Homologene: 40940
Olfr503
Name: olfactory receptor 503
Synonyms: GA_x6K02T2PBJ9-10874315-10875286, MOR34-9, MOR34-8P, MOR34-12, MOR34-9, Olfr1548
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259143
Homologene: 121509
Bend7
Name: BEN domain containing 7
Synonyms: 1110017O21Rik, E130319B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 209645
Homologene: 17660
Olfr295
Name: olfactory receptor 295
Synonyms: GA_x6K02T2NHDJ-9539243-9538314, MOR220-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258850
Homologene: 115526
Krt9
Name: keratin 9
Synonyms: K9, Krt1-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107656
HGNC: HGNC:6447
Homologene: 138337
Olfr57
Name: olfactory receptor 57
Synonyms: IF12, MOR139-3, GA_x6K02T2QGN0-2777431-2776472
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18357
HGNC: HGNC:8368
Homologene: 133620
Cldn17
Name: claudin 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239931
HGNC: HGNC:2038
Homologene: 8116
Trav3-1
Name: T cell receptor alpha variable 3-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 667441
Cfap91
Name: cilia and flagella associated protein 91
Synonyms: Spata26, 4932425I24Rik, Maats1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320214
Homologene: 33470
Ighv1-3
Name: immunoglobulin heavy variable V1-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780859
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 30,820,704 bp
  • A to G, chromosome 1 at 52,074,739 bp
  • T to A, chromosome 1 at 173,963,799 bp
  • T to C, chromosome 2 at 4,744,356 bp
  • T to C, chromosome 2 at 59,837,220 bp
  • T to C, chromosome 2 at 62,542,261 bp
  • G to A, chromosome 3 at 75,640,299 bp
  • T to A, chromosome 3 at 122,523,283 bp
  • T to C, chromosome 3 at 123,293,581 bp
  • C to T, chromosome 3 at 158,023,344 bp
  • C to T, chromosome 5 at 90,285,843 bp
  • G to T, chromosome 5 at 114,245,980 bp
  • G to A, chromosome 5 at 142,718,818 bp
  • T to C, chromosome 6 at 112,795,814 bp
  • T to A, chromosome 6 at 131,168,400 bp
  • A to T, chromosome 6 at 145,427,316 bp
  • A to T, chromosome 7 at 19,594,506 bp
  • G to A, chromosome 7 at 55,872,130 bp
  • A to G, chromosome 7 at 83,756,535 bp
  • T to A, chromosome 7 at 86,585,278 bp
  • A to T, chromosome 7 at 106,689,646 bp
  • G to A, chromosome 7 at 108,545,277 bp
  • T to C, chromosome 7 at 141,091,387 bp
  • A to T, chromosome 10 at 79,035,389 bp
  • T to A, chromosome 11 at 23,363,089 bp
  • G to T, chromosome 11 at 100,105,313 bp
  • C to T, chromosome 11 at 100,188,439 bp
  • C to T, chromosome 11 at 100,895,105 bp
  • T to C, chromosome 11 at 109,535,311 bp
  • T to A, chromosome 11 at 115,269,846 bp
  • T to A, chromosome 12 at 105,812,385 bp
  • T to C, chromosome 12 at 114,481,619 bp
  • T to C, chromosome 14 at 52,580,992 bp
  • A to G, chromosome 14 at 56,553,658 bp
  • T to C, chromosome 14 at 115,369,838 bp
  • A to C, chromosome 15 at 39,146,677 bp
  • T to C, chromosome 15 at 76,283,938 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • A to T, chromosome 15 at 77,423,767 bp
  • C to T, chromosome 16 at 17,574,356 bp
  • G to T, chromosome 16 at 38,328,310 bp
  • T to C, chromosome 16 at 88,506,709 bp
  • A to T, chromosome 17 at 19,589,507 bp
  • A to G, chromosome 17 at 32,357,697 bp
  • T to C, chromosome 17 at 35,013,644 bp
  • T to C, chromosome 17 at 47,692,308 bp
  • A to G, chromosome 17 at 83,446,043 bp
  • T to C, chromosome 18 at 34,949,023 bp
  • C to T, chromosome 19 at 12,674,919 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5944 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044136-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.