Strain Name:
C57BL/6J-MtgxR5959Btlr
Stock Number:
044146-MU
Citation ID:
RRID:MMRRC_044146-MU
Other Names:
R5959 (G1)
Major Collection:

Gene Information

Cnmd
Name: chondromodulin
Synonyms: Chmd, Bricd3, ChM-I, Chondromodulin 1, Lect1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16840
Homologene: 5095
Ahcyl2
Name: S-adenosylhomocysteine hydrolase-like 2
Synonyms: 4631427C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74340
Homologene: 69337
Srr
Name: serine racemase
Synonyms: M100034, Rgsc34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 27364
Homologene: 22775
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Uaca
Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms: 2700059D02Rik, nucling
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72565
VEGA: 9
Homologene: 74297
Rbm5
Name: RNA binding motif protein 5
Synonyms: D030069N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83486
HGNC: HGNC:9902
Homologene: 21177
Eed
Name: embryonic ectoderm development
Synonyms: l(7)5Rn, l7Rn5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13626
HGNC: HGNC:3188
Homologene: 2814
Cpne1
Name: copine I
Synonyms: 1810028N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 266692
HGNC: HGNC:2314
Homologene: 36501
Ptpn21
Name: protein tyrosine phosphatase, non-receptor type 21
Synonyms: PTPRL10, PTPD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 24000
VEGA: 12
HGNC: HGNC:9651
Homologene: 5110
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Ankrd28
Name: ankyrin repeat domain 28
Synonyms: E430019N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105522
VEGA: 14
Homologene: 35374
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, LOC327983, Acac, A530025K05Rik, Acc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Jak3
Name: Janus kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16453
HGNC: HGNC:6193
Homologene: 181
Acp6
Name: acid phosphatase 6, lysophosphatidic
Synonyms: mPACPL1, ACPL1, 5730559A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66659
Homologene: 41128
Kcnj3
Name: potassium inwardly-rectifying channel, subfamily J, member 3
Synonyms: Kir3.1, Kcnf3, GIRK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16519
HGNC: HGNC:6264
Homologene: 1687
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, Odz3, 2610100B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23965
Homologene: 22673
Zfyve27
Name: zinc finger, FYVE domain containing 27
Synonyms: 9530077C24Rik, 2210011N02Rik, protrudin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 319740
Homologene: 16939
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71169
VEGA: 12
Homologene: 41073
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Zc3hav1
Name: zinc finger CCCH type, antiviral 1
Synonyms: ZAP, 9830115L13Rik, 2900058M19Rik, 9130009D18Rik, 1200014N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78781
Homologene: 10585
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320714
Homologene: 11076
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Chga
Name: chromogranin A
Synonyms: ChrA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12652
VEGA: 12
HGNC: HGNC:1929
Homologene: 976
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: A330009G12Rik, LOC381663, Sec63d1, Mer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330149
Homologene: 87103
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Gramd4
Name: GRAM domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223752
Homologene: 18199
Myt1l
Name: myelin transcription factor 1-like
Synonyms: 2900093J19Rik, Pmng1, Nztf1, Png-1, 2900046C06Rik, C630034G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17933
VEGA: 12
HGNC: HGNC:7623
Homologene: 7435
Myo1c
Name: myosin IC
Synonyms: C80397, myosin-Ibeta, mm1beta, myr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Vmn2r80
Name: vomeronasal 2, receptor 80
Synonyms: EG624765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 624765
Homologene: 83483
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 50720
Prmt8
Name: protein arginine N-methyltransferase 8
Synonyms: Hrmt1l4, Hrmt1l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 381813
HGNC: HGNC:5188
Homologene: 76124
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319807
Homologene: 14974
Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Synonyms: 1300012D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71773
Homologene: 68144
Lpcat4
Name: lysophosphatidylcholine acyltransferase 4
Synonyms: Aytl3, Agpat7, LPEAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99010
Homologene: 27544
Zfp948
Name: zinc finger protein 948
Synonyms: BC049807
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381066
VEGA: 17
Cc2d1a
Name: coiled-coil and C2 domain containing 1A
Synonyms: Freud-1, Tape
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 212139
Homologene: 23040
Traf3ip2
Name: TRAF3 interacting protein 2
Synonyms: Act1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103213
HGNC: HGNC:1343
Homologene: 15885
Cfap221
Name: cilia and flagella associated protein 221
Synonyms: Gm101, Pcdp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226356
Homologene: 88578
Sorcs3
Name: sortilin-related VPS10 domain containing receptor 3
Synonyms: 6330404A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66673
VEGA: 19
Homologene: 8986
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78774
Olfr67
Name: olfactory receptor 67
Synonyms: MOR31-1, GA_x6K02T2PBJ9-6515150-6514170, 3'[b]1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18368
Homologene: 85930
Vwa2
Name: von Willebrand factor A domain containing 2
Synonyms: Amaco
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240675
Homologene: 18238
Vmn1r49
Name: vomeronasal 1, receptor 49
Synonyms: VRi2, V1r5, V1rb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 24112
Homologene: 113975
Ifnlr1
Name: interferon lambda receptor 1
Synonyms: Il28ra, CRF2-12, IFNLR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242700
Homologene: 52086
Fpr-rs7
Name: formyl peptide receptor, related sequence 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 321021
Rragc
Name: Ras-related GTP binding C
Synonyms: Gtr2, YGR163W, TIB929
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54170
Homologene: 39141
Olfr906
Name: olfactory receptor 906
Synonyms: MOR167-2, GA_x6K02T2PVTD-32194085-32195020
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258799
VEGA: 9
Homologene: 132439
Sox15
Name: SRY (sex determining region Y)-box 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20670
Homologene: 74586
Zfp703
Name: zinc finger protein 703
Synonyms: Zeppo1, Csmn1, End2, 1110032O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 353310
Homologene: 81391
Dguok
Name: deoxyguanosine kinase
Synonyms: dGK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27369
HGNC: HGNC:2858
Homologene: 8456
Rab15
Name: RAB15, member RAS oncogene family
Synonyms: 2310012G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104886
Homologene: 64471
Sowahc
Name: sosondowah ankyrin repeat domain family member C
Synonyms: Ankrd57, C820004L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 268301
Homologene: 49723
Sgol2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Dchs2
Name: dachsous cadherin related 2
Synonyms: LOC229459
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100534287
Gm12394
Name: predicted gene 12394
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100861727
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 119,932,781 bp
  • C to A, chromosome 2 at 52,156,377 bp
  • A to G, chromosome 2 at 55,437,318 bp
  • A to G, chromosome 2 at 76,714,616 bp
  • T to A, chromosome 2 at 76,863,505 bp
  • T to A, chromosome 2 at 112,240,035 bp
  • C to T, chromosome 2 at 145,947,133 bp
  • G to A, chromosome 2 at 156,078,223 bp
  • G to A, chromosome 3 at 83,325,418 bp
  • A to G, chromosome 3 at 97,166,572 bp
  • T to A, chromosome 4 at 42,793,492 bp
  • G to A, chromosome 4 at 123,923,974 bp
  • T to A, chromosome 4 at 135,705,341 bp
  • T to A, chromosome 5 at 63,808,070 bp
  • T to C, chromosome 5 at 86,925,954 bp
  • A to G, chromosome 5 at 106,874,917 bp
  • A to G, chromosome 6 at 29,886,174 bp
  • G to A, chromosome 6 at 38,307,444 bp
  • C to T, chromosome 6 at 83,490,592 bp
  • T to C, chromosome 6 at 90,072,804 bp
  • C to A, chromosome 6 at 127,729,418 bp
  • A to G, chromosome 7 at 89,969,627 bp
  • T to A, chromosome 7 at 103,787,516 bp
  • C to T, chromosome 8 at 26,979,205 bp
  • T to C, chromosome 8 at 47,501,558 bp
  • T to A, chromosome 8 at 48,646,447 bp
  • T to A, chromosome 8 at 63,927,288 bp
  • A to G, chromosome 8 at 71,682,071 bp
  • A to T, chromosome 8 at 84,133,503 bp
  • A to G, chromosome 9 at 38,488,911 bp
  • A to T, chromosome 9 at 60,870,770 bp
  • T to G, chromosome 9 at 107,752,140 bp
  • A to T, chromosome 10 at 39,641,341 bp
  • A to G, chromosome 10 at 59,223,098 bp
  • A to T, chromosome 10 at 79,169,479 bp
  • C to T, chromosome 11 at 69,655,730 bp
  • A to G, chromosome 11 at 74,911,065 bp
  • A to G, chromosome 11 at 75,657,519 bp
  • A to T, chromosome 11 at 84,215,966 bp
  • C to T, chromosome 11 at 120,808,564 bp
  • T to C, chromosome 12 at 13,288,801 bp
  • T to C, chromosome 12 at 29,920,040 bp
  • A to G, chromosome 12 at 76,822,269 bp
  • A to T, chromosome 12 at 98,708,889 bp
  • T to C, chromosome 12 at 102,561,855 bp
  • T to C, chromosome 14 at 31,729,922 bp
  • T to C, chromosome 14 at 61,212,400 bp
  • T to C, chromosome 14 at 79,656,669 bp
  • T to A, chromosome 15 at 86,127,557 bp
  • A to T, chromosome 16 at 35,298,410 bp
  • G to A, chromosome 17 at 20,113,749 bp
  • A to G, chromosome 17 at 21,587,514 bp
  • G to A, chromosome 18 at 34,632,415 bp
  • T to G, chromosome 19 at 42,179,448 bp
  • T to G, chromosome 19 at 48,749,396 bp
  • T to C, chromosome 19 at 56,881,172 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5959 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044146-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.