Strain Name:
C57BL/6J-MtgxR5960Btlr/Mmmh
Stock Number:
044147-MU
Citation ID:
RRID:MMRRC_044147-MU
Other Names:
R5960 (G1)
Major Collection:

Strain Information

Orc1
Name: origin recognition complex, subunit 1
Synonyms: Orc1l, MmORC1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18392
HGNC: HGNC:8487
Homologene: 31221
Cwf19l2
Name: CWF19 like cell cycle control factor 2
Synonyms: 3230401L03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244672
Homologene: 12366
Aopep
Name: aminopeptidase O
Synonyms: ApO, 2010111I01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72061
HGNC: HGNC:1361
Homologene: 66273
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: D630005A10Rik, apollon, A430032G04Rik, A430040A19Rik, Bruce
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12211
Homologene: 7248
Iars1
Name: isoleucyl-tRNA synthetase 1
Synonyms: E430001P04Rik, 2510016L12Rik, Iars
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105148
HGNC: HGNC:5330
Homologene: 5325
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11736
Homologene: 9491
Nup107
Name: nucleoporin 107
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103468
VEGA: 10
Homologene: 5555
Nhsl3
Name: NHS like 3
Synonyms: C77080
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 97130
Homologene: 45837
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 208836
Homologene: 49530
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Rbm26
Name: RNA binding motif protein 26
Synonyms: C230097K14Rik, Pro1777, 1700009P03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74213
Homologene: 41468
Cyth1
Name: cytohesin 1
Synonyms: CTH-1, Pscd1, CLM1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19157
HGNC: HGNC:9501
Homologene: 31262
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: PipkIII, Pip5k3, 5230400C17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18711
Homologene: 32115
Mtg1
Name: mitochondrial ribosome-associated GTPase 1
Synonyms: Gtpbp7, LOC212508
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212508
Homologene: 44527
Adat1
Name: adenosine deaminase, tRNA-specific 1
Synonyms: mADAT1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 30947
HGNC: HGNC:228
Homologene: 8096
Robo2
Name: roundabout guidance receptor 2
Synonyms: 9430089E08Rik, 2600013A04Rik, D230004I22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268902
Homologene: 43188
Ckmt1
Name: creatine kinase, mitochondrial 1, ubiquitous
Synonyms: Mt-CK, mi-CK, UbCKmit
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12716
Homologene: 69058
Syvn1
Name: synovial apoptosis inhibitor 1, synoviolin
Synonyms: 1200010C09Rik, Hrd1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74126
Homologene: 32700
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, Fath, 2310038E12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Setd6
Name: SET domain containing 6
Synonyms: 0610039J04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66083
Homologene: 38743
Susd2
Name: sushi domain containing 2
Synonyms: 1200011D11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71733
VEGA: 10
Homologene: 10481
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: 2900022L05Rik, Dnhd3, Dnahc2, D330014H01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Fam20a
Name: FAM20A, golgi associated secretory pathway pseudokinase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 208659
Homologene: 9719
Pigg
Name: phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms: Gpi7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433931
Homologene: 39421
4930579F01Rik
Name: RIKEN cDNA 4930579F01 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67741
Homologene: 12962
Itgb2l
Name: integrin beta 2-like
Synonyms: pactolus, 5033406G21Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16415
HGNC: HGNC:6155
Cfap126
Name: cilia and flagella associated protein 126
Synonyms: Fltp, 1700009P17Rik, Flattop
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75472
Homologene: 23682
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: PBP, Moca
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: E230025N21Rik, Kif16a, 4831403C07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 2900056O04Rik, 0610038H21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68379
Homologene: 8112
Synm
Name: synemin, intermediate filament protein
Synonyms: Synemin, Dmn, 4930412K21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233335
Homologene: 9081
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Nhsl1
Name: NHS like 1
Synonyms: D10Bwg0940e, A630035H13Rik, 5730409E15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215819
Homologene: 27834
Caskin1
Name: CASK interacting protein 1
Synonyms: C630036E02Rik, 3300002N10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268932
VEGA: 17
Homologene: 25873
Fndc8
Name: fibronectin type III domain containing 8
Synonyms: 4930466G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78919
Homologene: 9716
Paox
Name: polyamine oxidase (exo-N4-amino)
Synonyms: Pao, 2410012F02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212503
Homologene: 72096
Spmap2
Name: sperm microtubule associated protein 2
Synonyms: Theg
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21830
Homologene: 7976
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
Or5m13
Name: olfactory receptor family 5 subfamily M member 13
Synonyms: MOR196-5P, Olfr1025, MOR196-6_p, GA_x6K02T2Q125-47397266-47398205
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258083
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 329015
Homologene: 86985
Prpf40b
Name: pre-mRNA processing factor 40B
Synonyms: 2610317D23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54614
Homologene: 81828
Prickle2
Name: prickle planar cell polarity protein 2
Synonyms: Pk2, 6720451F06Rik, 6230400G14Rik, mpk2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243548
Homologene: 17889
Tph1
Name: tryptophan hydroxylase 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21990
Homologene: 121565
Rasgrf1
Name: RAS protein-specific guanine nucleotide-releasing factor 1
Synonyms: CDC25, Grfbeta, CDC25Mm, Grf1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19417
HGNC: HGNC:9875
Homologene: 74972
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: 3000002F19Rik, STEF
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Pck2
Name: phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Synonyms: 9130022B02Rik, 1810010O14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74551
VEGA: 14
HGNC: HGNC:8725
Homologene: 3356
Megf11
Name: multiple EGF-like-domains 11
Synonyms: 2410080H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214058
Homologene: 13031
Alcam
Name: activated leukocyte cell adhesion molecule
Synonyms: BEN, MuSC, SC1, CD166, DM-GRASP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11658
HGNC: HGNC:400
Homologene: 1229
Usp45
Name: ubiquitin specific petidase 45
Synonyms: 3110003C05Rik, Gcap7, 4930550B20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77593
Homologene: 17674
Catsperg1
Name: cation channel sperm associated auxiliary subunit gamma 1
Synonyms: Catsperg, A230107C01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320225
Homologene: 10915
Sncb
Name: synuclein, beta
Synonyms: betaSYN
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 104069
Homologene: 2320
Ddx25
Name: DEAD box helicase 25
Synonyms: GRTH, DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 30959
Homologene: 8310
Tymp
Name: thymidine phosphorylase
Synonyms: gliostatin, 2900072D10Rik, PD-ECGF, PDECGF, Ecgf1, Pdgfec
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72962
VEGA: 15
HGNC: HGNC:3148
Homologene: 1474
Ifi209
Name: interferon activated gene 209
Synonyms: Ifix, Pyhin1, Pyhin-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 236312
HGNC: HGNC:5395
Homologene: 115929
Gm9755
Name: predicted pseudogene 9755
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100041265
Or51a24
Name: olfactory receptor family 51 subfamily A member 24
Synonyms: Olfr645, GA_x6K02T2PBJ9-6819097-6818150, MOR13-5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258247
Homologene: 66155
Smim35
Name: small integral membrane protein 35
Synonyms: BC049352
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 408059
Homologene: 136435
Nudt16
Name: nudix hydrolase 16
Synonyms: 2810047L04Rik, nudix (nucleoside diphosphate linked moiety X)-type motif 16, 2310041H06Rik, 2900006H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75686
Homologene: 12617
Gm19965
Name: predicted gene, 19965
Type: Gene
Species: Mouse
Chromosome: 1
2810428I15Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Trav7-5
Name: T cell receptor alpha variable 7-5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 630061
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 26,683,144 bp
  • C to A, chromosome 1 at 65,253,438 bp
  • T to C, chromosome 1 at 116,821,471 bp
  • A to G, chromosome 1 at 171,125,313 bp
  • A to T, chromosome 1 at 173,638,816 bp
  • C to A, chromosome 2 at 32,371,216 bp
  • T to A, chromosome 2 at 85,918,725 bp
  • A to G, chromosome 2 at 120,699,961 bp
  • T to A, chromosome 2 at 121,363,577 bp
  • T to C, chromosome 3 at 138,183,767 bp
  • A to C, chromosome 4 at 21,810,797 bp
  • T to C, chromosome 4 at 108,606,298 bp
  • A to G, chromosome 4 at 129,222,072 bp
  • A to G, chromosome 5 at 108,336,294 bp
  • A to G, chromosome 6 at 92,376,305 bp
  • A to G, chromosome 7 at 29,184,783 bp
  • A to G, chromosome 7 at 46,662,005 bp
  • A to G, chromosome 7 at 67,735,746 bp
  • A to G, chromosome 7 at 79,443,762 bp
  • G to T, chromosome 7 at 104,084,353 bp
  • A to G, chromosome 7 at 140,132,489 bp
  • T to C, chromosome 7 at 140,146,993 bp
  • C to T, chromosome 8 at 16,071,416 bp
  • T to C, chromosome 8 at 45,033,368 bp
  • T to G, chromosome 8 at 67,515,188 bp
  • C to A, chromosome 8 at 70,506,506 bp
  • T to A, chromosome 8 at 95,716,199 bp
  • T to C, chromosome 8 at 111,982,601 bp
  • A to G, chromosome 9 at 3,411,404 bp
  • A to G, chromosome 9 at 35,554,511 bp
  • T to C, chromosome 9 at 45,242,990 bp
  • A to G, chromosome 9 at 64,660,449 bp
  • A to G, chromosome 9 at 90,021,384 bp
  • A to T, chromosome 9 at 105,131,499 bp
  • C to A, chromosome 9 at 106,911,355 bp
  • T to G, chromosome 10 at 18,526,976 bp
  • C to T, chromosome 10 at 75,639,936 bp
  • T to G, chromosome 10 at 79,585,931 bp
  • T to C, chromosome 10 at 117,790,010 bp
  • C to T, chromosome 11 at 69,458,920 bp
  • T to A, chromosome 11 at 72,757,352 bp
  • A to G, chromosome 11 at 82,897,572 bp
  • G to A, chromosome 11 at 109,675,969 bp
  • A to G, chromosome 11 at 118,132,367 bp
  • T to C, chromosome 13 at 49,724,637 bp
  • A to G, chromosome 13 at 54,762,982 bp
  • G to A, chromosome 13 at 63,240,273 bp
  • T to A, chromosome 14 at 53,531,249 bp
  • A to G, chromosome 14 at 55,548,547 bp
  • A to G, chromosome 14 at 61,208,695 bp
  • A to T, chromosome 14 at 105,150,315 bp
  • A to G, chromosome 15 at 21,492,476 bp
  • A to T, chromosome 15 at 89,376,575 bp
  • G to T, chromosome 15 at 99,314,904 bp
  • T to C, chromosome 16 at 14,152,417 bp
  • T to C, chromosome 16 at 52,295,126 bp
  • A to T, chromosome 16 at 73,933,715 bp
  • T to C, chromosome 16 at 96,426,259 bp
  • A to T, chromosome 17 at 3,438,640 bp
  • A to G, chromosome 17 at 24,498,895 bp
  • A to T, chromosome 17 at 74,528,765 bp
  • C to T, chromosome 19 at 6,050,568 bp
  • T to G, chromosome 19 at 6,254,360 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5960 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044147-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.