Strain Name:
C57BL/6J-MtgxR5980Btlr
Stock Number:
044162-MU
Citation ID:
RRID:MMRRC_044162-MU
Other Names:
R5980 (G1)
Major Collection:

Gene Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: dyn, SpbIV, neuroaxonal dystrophy, 5830426A08Rik, ROSA62, nmf261, 1700022P15Rik, Spnb4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80297
Homologene: 11879
Atg7
Name: autophagy related 7
Synonyms: 1810013K23Rik, Apg7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74244
Homologene: 4662
Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: 1110067B02Rik, Sema6D-6, Sema6D-5, Sema6D-4, Sema6D-2, Sema6D-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214968
Homologene: 16195
Nrcam
Name: neuronal cell adhesion molecule
Synonyms: Bravo, C030017F07Rik, C130076O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319504
VEGA: 12
HGNC: HGNC:7994
Homologene: 21041
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Ep400
Name: E1A binding protein p400
Synonyms: p400, mDomino, 1700020J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75560
Homologene: 38779
Mta3
Name: metastasis associated 3
Synonyms: 1110002J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 116871
Homologene: 14282
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, Gp330, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Kansl1
Name: KAT8 regulatory NSL complex subunit 1
Synonyms: 1700081L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76719
Homologene: 9140
Ticrr
Name: TOPBP1-interacting checkpoint and replication regulator
Synonyms: 5730590G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77011
Homologene: 67120
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382034
Homologene: 40964
Cep104
Name: centrosomal protein 104
Synonyms: BC046331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230967
Homologene: 44919
Gpi1
Name: glucose-6-phosphate isomerase 1
Synonyms: Org, Gpi-1t, Gpi-1, Gpi-1s, Gpi-1r, Gpi1-t, Gpi1-s, Gpi1-r, MF, maturation factor, NK, AMF, autocrine motility factor, neuroleukin, NK/GPI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14751
HGNC: HGNC:4458
Homologene: 145
Ago1
Name: argonaute RISC catalytic subunit 1
Synonyms: argonaute 1, Eif2c1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 236511
HGNC: HGNC:3262
Homologene: 81826
Prdm15
Name: PR domain containing 15
Synonyms: Zfp298, E130018M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 114604
Homologene: 56941
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, 2310003F20Rik, Tulip1, Garnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Mycbp
Name: MYC binding protein
Synonyms: Amy-1, 5730488M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56309
HGNC: HGNC:7554
Homologene: 49312
Sfrp5
Name: secreted frizzled-related sequence protein 5
Synonyms: SARP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 54612
Homologene: 2268
Syt14
Name: synaptotagmin XIV
Synonyms: B230320I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329324
Homologene: 17719
Magel2
Name: MAGE family member L2
Synonyms: NDNL1, Mage-l2, nM15, ns7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27385
HGNC: HGNC:6814
Homologene: 8460
Ighmbp2
Name: immunoglobulin mu binding protein 2
Synonyms: Catf1, AEP, Smbp2, sma, Smubp2, p110 subunit, RIPE3b1, Smbp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20589
HGNC: HGNC:5542
Homologene: 1642
Mtmr4
Name: myotubularin related protein 4
Synonyms: ESTM44, FYVE-DSP2, FYVE zinc finger phosphatase, ZFYVE11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 170749
HGNC: HGNC:7452
Homologene: 3440
Tbc1d2
Name: TBC1 domain family, member 2
Synonyms: LOC381605, PARIS-1, PARIS1, A630005A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381605
Homologene: 10190
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67498
VEGA: 15
Homologene: 22811
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232400
Homologene: 45969
Vmn2r83
Name: vomeronasal 2, receptor 83
Synonyms: EG625029
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625029
Homologene: 83669
Nol4
Name: nucleolar protein 4
Synonyms: 4930568N03Rik, LOC383304, 1700013J13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319211
HGNC: HGNC:7870
Homologene: 36142
Tmem132d
Name: transmembrane protein 132D
Synonyms: C630028F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243274
Homologene: 71684
Hid1
Name: HID1 domain containing
Synonyms: C630004H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217310
Homologene: 12737
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628422
Sidt1
Name: SID1 transmembrane family, member 1
Synonyms: B830021E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320007
Homologene: 41189
Apol6
Name: apolipoprotein L 6
Synonyms: 2310076O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71939
Homologene: 49940
Ngly1
Name: N-glycanase 1
Synonyms: 1110002C09Rik, Png1, PNGase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 59007
Homologene: 10117
Pom121l2
Name: POM121 membrane glycoprotein-like 2 (rat)
Synonyms: LOC195236
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195236
Homologene: 123536
Olfr1058
Name: olfactory receptor 1058
Synonyms: GA_x6K02T2Q125-47855818-47854868, MOR190-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258386
Homologene: 74093
Vmn2r95
Name: vomeronasal 2, receptor 95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328759
Homologene: 115024
Pik3c2b
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms: PI3K-C2beta, C330011J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240752
HGNC: HGNC:8972
Homologene: 20582
Cntn6
Name: contactin 6
Synonyms: NB-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53870
HGNC: HGNC:2176
Homologene: 8702
Olfr993
Name: olfactory receptor 993
Synonyms: GA_x6K02T2Q125-46891524-46890580, MOR203-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258427
Homologene: 79352
Arhgap27
Name: Rho GTPase activating protein 27
Synonyms: 2310069I04Rik, 5730442P18Rik, Sh3d20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544817
Homologene: 45715
Trafd1
Name: TRAF type zinc finger domain containing 1
Synonyms: 1110008K06Rik, Fln29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231712
Homologene: 31399
Cers4
Name: ceramide synthase 4
Synonyms: 2900019C14Rik, Trh1, CerS4, Lass4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67260
Homologene: 11582
Saraf
Name: store-operated calcium entry-associated regulatory factor
Synonyms: 1810045K07Rik, Tmem66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67887
Homologene: 9398
Olfr9
Name: olfactory receptor 9
Synonyms: MOR269-3, GA_x6K02T2PULF-10675610-10676548
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18373
Homologene: 85121
Trim68
Name: tripartite motif-containing 68
Synonyms: SS-56, F730114J12Rik, Rnf137
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101700
Homologene: 9991
Lysmd1
Name: LysM, putative peptidoglycan-binding, domain containing 1
Synonyms: 2610022K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 217779
Homologene: 41742
Irgq
Name: immunity-related GTPase family, Q
Synonyms: FKSG27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210146
Homologene: 17696
Pate10
Name: prostate and testis expressed 10
Synonyms: Gm17677
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100312949
Homologene: 130079
Igkv10-95
Name: immunoglobulin kappa variable 10-95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434031
Igkv14-100
Name: immunoglobulin kappa chain variable 14-100
Synonyms: Gm16635
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243439
Mup11
Name: major urinary protein 11
Synonyms: Gm12549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100039028
Homologene: 74304
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 34,182,891 bp
  • C to A, chromosome 1 at 133,088,308 bp
  • T to C, chromosome 1 at 192,980,408 bp
  • A to T, chromosome 2 at 69,535,005 bp
  • A to T, chromosome 2 at 85,414,165 bp
  • A to T, chromosome 2 at 86,385,797 bp
  • A to G, chromosome 2 at 124,664,708 bp
  • A to G, chromosome 2 at 125,315,404 bp
  • A to T, chromosome 3 at 95,137,908 bp
  • C to T, chromosome 4 at 46,629,912 bp
  • A to G, chromosome 4 at 60,660,888 bp
  • G to A, chromosome 4 at 123,911,096 bp
  • C to T, chromosome 4 at 126,460,569 bp
  • C to A, chromosome 4 at 153,988,473 bp
  • G to A, chromosome 5 at 110,733,729 bp
  • A to G, chromosome 5 at 121,373,457 bp
  • T to A, chromosome 5 at 127,784,598 bp
  • T to C, chromosome 6 at 68,519,025 bp
  • T to C, chromosome 6 at 68,680,589 bp
  • T to C, chromosome 6 at 73,181,722 bp
  • T to C, chromosome 6 at 104,848,132 bp
  • C to A, chromosome 6 at 114,680,236 bp
  • T to C, chromosome 6 at 128,567,055 bp
  • G to A, chromosome 7 at 24,533,345 bp
  • A to G, chromosome 7 at 27,372,171 bp
  • A to G, chromosome 7 at 34,228,926 bp
  • T to A, chromosome 7 at 41,865,056 bp
  • A to T, chromosome 7 at 62,380,596 bp
  • G to A, chromosome 7 at 79,660,955 bp
  • A to G, chromosome 7 at 102,678,831 bp
  • T to A, chromosome 8 at 4,518,269 bp
  • T to A, chromosome 8 at 34,165,387 bp
  • T to G, chromosome 8 at 120,229,637 bp
  • A to C, chromosome 9 at 35,741,615 bp
  • T to A, chromosome 10 at 79,478,792 bp
  • A to G, chromosome 10 at 128,990,440 bp
  • T to C, chromosome 11 at 87,604,151 bp
  • T to C, chromosome 11 at 103,356,269 bp
  • T to C, chromosome 11 at 104,343,637 bp
  • G to A, chromosome 11 at 115,350,948 bp
  • T to C, chromosome 12 at 44,571,633 bp
  • T to A, chromosome 12 at 55,770,616 bp
  • T to C, chromosome 13 at 21,983,376 bp
  • A to C, chromosome 14 at 16,270,509 bp
  • C to A, chromosome 15 at 45,109,414 bp
  • A to T, chromosome 15 at 77,051,019 bp
  • A to T, chromosome 16 at 44,263,312 bp
  • G to A, chromosome 16 at 97,812,570 bp
  • A to G, chromosome 17 at 18,441,362 bp
  • T to A, chromosome 17 at 83,708,405 bp
  • T to A, chromosome 18 at 22,952,201 bp
  • G to T, chromosome 19 at 3,265,295 bp
  • A to T, chromosome 19 at 42,201,972 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5980 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044162-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.