Strain Name:
C57BL/6J-MtgxR5985Btlr
Stock Number:
044165-MU
Citation ID:
RRID:MMRRC_044165-MU
Other Names:
R5985 (G1)
Major Collection:

Gene Information

Spns1
Name: spinster homolog 1
Synonyms: 2210013K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73658
Homologene: 41530
Zfp423
Name: zinc finger protein 423
Synonyms: ataxia1, Zfp104, Ebfaz, Roaz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94187
Homologene: 9010
Mtmr7
Name: myotubularin related protein 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54384
HGNC: HGNC:7454
Homologene: 99732
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: spkw1, Gluralpha4, Glur-4, Glur4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Armh3
Name: armadillo-like helical domain containing 3
Synonyms: 9130011E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71617
VEGA: 19
Homologene: 15843
Sik3
Name: SIK family kinase 3
Synonyms: 9030204A07Rik, 5730525O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70661
Homologene: 57023
Gan
Name: giant axonal neuropathy
Synonyms: gigaxonin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209239
HGNC: HGNC:4137
Homologene: 32523
Trip12
Name: thyroid hormone receptor interactor 12
Synonyms: 6720416K24Rik, 1110036I07Rik, Gtl6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14897
Homologene: 44226
Actn1
Name: actinin, alpha 1
Synonyms: 3110023F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109711
VEGA: 12
HGNC: HGNC:163
Homologene: 55553
Safb2
Name: scaffold attachment factor B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224902
Homologene: 35210
Gas2
Name: growth arrest specific 2
Synonyms: Gas-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14453
HGNC: HGNC:4167
Homologene: 31301
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: QBRICK, eyem02Jus, eyes2, crf11, heb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329872
Homologene: 27049
Ankrd10
Name: ankyrin repeat domain 10
Synonyms: 4833425P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102334
Homologene: 9768
Prox1
Name: prospero homeobox 1
Synonyms: A230003G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19130
HGNC: HGNC:9459
Homologene: 2069
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 386750
Homologene: 8955
Zfp473
Name: zinc finger protein 473
Synonyms: D030014N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243963
Homologene: 18698
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: Atp1al1, ATPase H+K+-transporting, alpha 2, cHKA, HKalpha2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192113
VEGA: 14
Homologene: 68197
Trpc7
Name: transient receptor potential cation channel, subfamily C, member 7
Synonyms: TRP7, Trrp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 26946
Homologene: 22689
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: Nesp2g, nesprin-2, syne-2, Cpfl8, diminished cone electroretinogram, 6820443O06Rik, dice, D12Ertd777e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545874
Homologene: 135915
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 329015
Homologene: 86985
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240753
Homologene: 135779
Gli3
Name: GLI-Kruppel family member GLI3
Synonyms: Bph, brachyphalangy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14634
HGNC: HGNC:4319
Homologene: 139
Speg
Name: SPEG complex locus
Synonyms: SPEG, SPEGbeta, BPEG, Apeg1, SPEGalpha, D1Bwg1450e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11790
Homologene: 55619
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
B4galnt3
Name: beta-1,4-N-acetyl-galactosaminyl transferase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330406
Homologene: 18328
Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Synonyms: 1300012D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71773
Homologene: 68144
Tph1
Name: tryptophan hydroxylase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21990
Homologene: 121565
Gal3st2
Name: galactose-3-O-sulfotransferase 2
Synonyms: LOC381334
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381334
Homologene: 41471
Myod1
Name: myogenic differentiation 1
Synonyms: Myod-1, MYF3, bHLHc1, MyoD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17927
HGNC: HGNC:7611
Homologene: 7857
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: 5031409J19Rik, Gpr110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77596
Homologene: 124643
Olfr1156
Name: olfactory receptor 1156
Synonyms: MOR174-3, GA_x6K02T2Q125-49433499-49432537
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258814
HGNC: HGNC:8351
Homologene: 72031
Vmn2r14
Name: vomeronasal 2, receptor 14
Synonyms: EG231591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231591
Homologene: 129606
Ttll13
Name: tubulin tyrosine ligase-like family, member 13
Synonyms: 1700111A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269954
Homologene: 136186
Rnf144a
Name: ring finger protein 144A
Synonyms: Rnf144, UIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 108089
VEGA: 12
Homologene: 40982
Ankrd29
Name: ankyrin repeat domain 29
Synonyms: G630054C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225187
Homologene: 17839
Card10
Name: caspase recruitment domain family, member 10
Synonyms: Bimp1, CARMA3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105844
Homologene: 8728
Cpeb3
Name: cytoplasmic polyadenylation element binding protein 3
Synonyms: 4831444O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 208922
Homologene: 40992
Vmn1r36
Name: vomeronasal 1 receptor 36
Synonyms: V1rc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171184
Homologene: 110800
Terb1
Name: telomere repeat binding bouquet formation protein 1
Synonyms: Ccdc79, 4930532D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320022
Homologene: 18330
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Herpud1
Name: homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Synonyms: Herp, Mifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64209
Homologene: 40973
Phf11b
Name: PHD finger protein 11B
Synonyms: Gm4902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 236451
Homologene: 87807
Faap20
Name: Fanconi anemia core complex associated protein 20
Synonyms: 2610002J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67513
Homologene: 18793
Klf15
Name: Kruppel-like factor 15
Synonyms: hlb444, KKLF, 1810013I09Rik, CKLF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66277
Homologene: 8553
Gm3898
Name: predicted gene 3898
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100042548
VEGA: 9
Olfr1150-ps1
Name: olfactory receptor 1150, pseudogene 1
Synonyms: MOR264-11, GA_x6K02T2Q125-49347783-49348734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258104
Defb37
Name: defensin beta 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 353320
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 75,406,684 bp
  • T to A, chromosome 1 at 84,725,771 bp
  • T to C, chromosome 1 at 93,873,613 bp
  • G to C, chromosome 1 at 133,272,307 bp
  • A to T, chromosome 1 at 190,146,955 bp
  • A to G, chromosome 2 at 87,357,605 bp
  • A to G, chromosome 2 at 87,949,321 bp
  • T to C, chromosome 3 at 73,050,900 bp
  • T to C, chromosome 4 at 47,284,507 bp
  • C to T, chromosome 4 at 82,966,050 bp
  • T to C, chromosome 4 at 155,250,340 bp
  • T to C, chromosome 5 at 86,919,668 bp
  • A to T, chromosome 5 at 109,220,216 bp
  • A to C, chromosome 5 at 137,446,037 bp
  • T to A, chromosome 6 at 66,716,871 bp
  • G to A, chromosome 6 at 90,466,721 bp
  • G to A, chromosome 6 at 120,210,158 bp
  • A to G, chromosome 6 at 123,823,628 bp
  • C to A, chromosome 7 at 3,737,317 bp
  • C to T, chromosome 7 at 44,733,328 bp
  • A to G, chromosome 7 at 46,377,798 bp
  • A to G, chromosome 7 at 46,653,781 bp
  • T to A, chromosome 7 at 51,943,676 bp
  • C to T, chromosome 7 at 80,254,638 bp
  • G to A, chromosome 7 at 126,376,730 bp
  • T to A, chromosome 8 at 11,619,077 bp
  • A to T, chromosome 8 at 18,986,331 bp
  • A to G, chromosome 8 at 40,551,832 bp
  • A to T, chromosome 8 at 87,782,146 bp
  • G to A, chromosome 8 at 94,390,794 bp
  • A to T, chromosome 8 at 104,451,807 bp
  • A to G, chromosome 8 at 104,482,316 bp
  • C to T, chromosome 8 at 117,195,818 bp
  • T to C, chromosome 9 at 4,503,593 bp
  • G to A, chromosome 9 at 43,830,032 bp
  • A to G, chromosome 9 at 46,211,675 bp
  • A to C, chromosome 11 at 9,291,628 bp
  • C to T, chromosome 12 at 26,317,780 bp
  • C to G, chromosome 12 at 75,966,159 bp
  • C to A, chromosome 12 at 80,168,395 bp
  • A to G, chromosome 13 at 15,723,555 bp
  • A to G, chromosome 13 at 56,810,545 bp
  • A to G, chromosome 14 at 56,384,341 bp
  • A to G, chromosome 14 at 59,321,578 bp
  • T to C, chromosome 15 at 78,791,211 bp
  • T to C, chromosome 17 at 43,293,255 bp
  • T to C, chromosome 17 at 56,563,181 bp
  • G to A, chromosome 18 at 12,279,775 bp
  • A to G, chromosome 19 at 6,254,637 bp
  • T to C, chromosome 19 at 37,087,552 bp
  • A to T, chromosome 19 at 45,820,324 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5985 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044165-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.