Strain Name:
C57BL/6J-MtgxR5986Btlr
Stock Number:
044166-MU
Citation ID:
RRID:MMRRC_044166-MU
Other Names:
R5986 (G1)
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-2, Gm4392, Ank-2, ankyrin B, Ankyrin-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109676
HGNC: HGNC:493
Pcdh9
Name: protocadherin 9
Synonyms: A730003J17Rik, LOC382930, 1500001L12Rik, C630029H24Rik, C530050I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Osbpl1a
Name: oxysterol binding protein-like 1A
Synonyms: G430090F17Rik, LOC328902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 64291
Homologene: 84746
Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70797
Homologene: 19076
Dpp3
Name: dipeptidylpeptidase 3
Synonyms: 4930533O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 75221
VEGA: 19
HGNC: HGNC:3008
Homologene: 40210
Ptbp3
Name: polypyrimidine tract binding protein 3
Synonyms: 5830471K22Rik, Rod1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230257
Homologene: 55872
Cog5
Name: component of oligomeric golgi complex 5
Synonyms: GOLTC1, GTC90, 5430405C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238123
VEGA: 12
Homologene: 42221
Nup107
Name: nucleoporin 107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103468
VEGA: 10
Homologene: 5555
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 21844
Homologene: 2443
Ppp2r1a
Name: protein phosphatase 2, regulatory subunit A, alpha
Synonyms: PR65, 6330556D22Rik, protein phosphatase PP2A, PP2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 51792
HGNC: HGNC:9302
Homologene: 68559
Mars
Name: methionine-tRNA synthetase
Synonyms: methionyl-tRNA synthetase, MetRS, methionine tRNA ligase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216443
HGNC: HGNC:6898
Homologene: 90878
Zfp442
Name: zinc finger protein 442
Synonyms: OTTMUSG00000015730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668923
Homologene: 136215
Rassf1
Name: Ras association (RalGDS/AF-6) domain family member 1
Synonyms: Rassf1C, RDA32, NORE2A, Rassf1A, REH3P21, Rassf1B, 123F protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56289
HGNC: HGNC:9882
Homologene: 10499
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Yju2
Name: YJU2 splicing factor
Synonyms: 2900016D05Rik, Ccdc94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72886
VEGA: 17
Homologene: 6350
St8sia5
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
Synonyms: ST8SiaV, Siat8e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225742
Homologene: 8331
Lhfpl3
Name: lipoma HMGIC fusion partner-like 3
Synonyms: A930031L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269629
HGNC: HGNC:6589
Homologene: 26732
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Bccip
Name: BRCA2 and CDKN1A interacting protein
Synonyms: TOK-1, 1110013J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66165
HGNC: HGNC:978
Homologene: 41629
Pigk
Name: phosphatidylinositol glycan anchor biosynthesis, class K
Synonyms: 3000001O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329777
HGNC: HGNC:8965
Homologene: 4002
Mettl16
Name: methyltransferase like 16
Synonyms: Mett10d, 2610100D03Rik, A830095F14Rik, 2810013M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67493
Homologene: 34653
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, C230081A13Rik, NKF3 kinase family member
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244895
Homologene: 18259
Sec22a
Name: SEC22 homolog A, vesicle trafficking protein
Synonyms: Sec22l2, 1810005C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 317717
Homologene: 8246
Tpsb2
Name: tryptase beta 2
Synonyms: MMCP-6, Mcp6, Mcpt6, Mcp-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17229
VEGA: 17
Homologene: 55729
Nutm2
Name: NUT family member 2
Synonyms: Gm806, LOC328250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 328250
Homologene: 128615
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: 3110001A05Rik, 3110027P15Rik, 1810064L21Rik, Ugcgl2, A230065J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66435
Homologene: 56875
Slc1a5
Name: solute carrier family 1 (neutral amino acid transporter), member 5
Synonyms: ASCT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20514
Homologene: 21155
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC382129, 9430076A06Rik, LOC234973, D430038H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270120
VEGA: 9
Homologene: 82252
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 1110061O17Rik, 9630046L06Rik, 9430004C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Olfm2
Name: olfactomedin 2
Synonyms: A030009A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244723
VEGA: 9
Homologene: 14380
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242627
Homologene: 135888
Mrps30
Name: mitochondrial ribosomal protein S30
Synonyms: 2610020A16Rik, Pdcd9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 59054
HGNC: HGNC:8769
Homologene: 9607
Kif9
Name: kinesin family member 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16578
Homologene: 65620
Wdr31
Name: WD repeat domain 31
Synonyms: 5430402I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 71354
Homologene: 11360
Chl1
Name: cell adhesion molecule L1-like
Synonyms: close homolog of L1, LICAM2, A530023M13Rik, CALL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Gm13128
Name: predicted gene 13128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 626995
Homologene: 129642
Nepn
Name: nephrocan
Synonyms: Npn, 5730521E12Rik, periolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66650
Homologene: 23549
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240753
Homologene: 135779
Olfr27
Name: olfactory receptor 27
Synonyms: MTPCR56, GA_x6K02T2PVTD-32841223-32842158, MOR171-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258826
VEGA: 9
Homologene: 110610
Osmr
Name: oncostatin M receptor
Synonyms: OSMRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18414
HGNC: HGNC:8507
Homologene: 2972
Ampd1
Name: adenosine monophosphate deaminase 1
Synonyms: Ampd-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229665
HGNC: HGNC:468
Homologene: 20
Nrn1
Name: neuritin 1
Synonyms: cpg15, 0710008J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68404
Homologene: 9577
Dffb
Name: DNA fragmentation factor, beta subunit
Synonyms: DFF40, CAD, CPAN, caspase-activated DNase, 40kDa, Didff, 5730477D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13368
HGNC: HGNC:2773
Homologene: 3241
Vmn1r115
Name: vomeronasal 1 receptor 115
Synonyms: Gm8549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667273
Homologene: 104166
Kcnk3
Name: potassium channel, subfamily K, member 3
Synonyms: Task-1, cTBAK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16527
HGNC: HGNC:6278
Homologene: 1692
Xrra1
Name: X-ray radiation resistance associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 446101
Homologene: 19547
Cep250
Name: centrosomal protein 250
Synonyms: B230210E21Rik, Cep2, Inmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Cyp4f16
Name: cytochrome P450, family 4, subfamily f, polypeptide 16
Synonyms: 2310021J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 70101
Homologene: 135840
Myrip
Name: myosin VIIA and Rab interacting protein
Synonyms: A230081N12Rik, Slac2-c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245049
Homologene: 9150
Tll1
Name: tolloid-like
Synonyms: Tll-1, b2b2476Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21892
Homologene: 49202
Mgat2
Name: mannoside acetylglucosaminyltransferase 2
Synonyms: GNT2, GNT-II, CDGS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217664
HGNC: HGNC:7045
Homologene: 1806
Mapk10
Name: mitogen-activated protein kinase 10
Synonyms: JNK3, C230008H04Rik, p493F12, Serk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26414
HGNC: HGNC:6872
Homologene: 56439
Olfr592
Name: olfactory receptor 592
Synonyms: GA_x6K02T2PBJ9-5902266-5903204, Olfr1525-ps1, MOR0-3P, MOR0-3P, MOR32-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404317
Homologene: 66215
Ptgr2
Name: prostaglandin reductase 2
Synonyms: 9630002F03Rik, Zadh1, PGR-2, 1810016I24Rik, B830026H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 77219
Homologene: 39824
ccdc198
Name: coiled-coil domain containing 198
Synonyms: 1700011H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67082
Homologene: 49528
Ly6c1
Name: lymphocyte antigen 6 complex, locus C1
Synonyms: Ly6c, Ly-6C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17067
Homologene: 113718
Trib1
Name: tribbles pseudokinase 1
Synonyms: A530090O15Rik, Trb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 211770
Homologene: 75216
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to C, chromosome 1 at 133,272,307 bp
  • G to A, chromosome 2 at 150,408,024 bp
  • A to G, chromosome 2 at 155,979,277 bp
  • T to C, chromosome 3 at 103,085,397 bp
  • A to T, chromosome 3 at 116,772,496 bp
  • T to C, chromosome 3 at 127,012,686 bp
  • A to T, chromosome 3 at 152,740,849 bp
  • T to C, chromosome 4 at 59,493,311 bp
  • A to G, chromosome 4 at 62,455,876 bp
  • C to T, chromosome 4 at 113,995,648 bp
  • G to T, chromosome 4 at 144,332,753 bp
  • A to T, chromosome 4 at 153,965,593 bp
  • T to C, chromosome 5 at 3,747,071 bp
  • C to A, chromosome 5 at 22,746,426 bp
  • T to C, chromosome 5 at 30,588,378 bp
  • T to C, chromosome 5 at 103,038,580 bp
  • C to A, chromosome 6 at 103,709,191 bp
  • T to C, chromosome 7 at 16,782,226 bp
  • G to A, chromosome 7 at 20,844,522 bp
  • T to C, chromosome 7 at 99,876,255 bp
  • T to C, chromosome 7 at 103,187,528 bp
  • T to A, chromosome 7 at 133,720,865 bp
  • T to C, chromosome 8 at 64,074,263 bp
  • T to A, chromosome 9 at 15,998,317 bp
  • C to T, chromosome 9 at 20,675,650 bp
  • A to G, chromosome 9 at 39,144,982 bp
  • A to C, chromosome 9 at 56,259,442 bp
  • G to T, chromosome 9 at 107,551,822 bp
  • G to A, chromosome 9 at 110,490,026 bp
  • C to A, chromosome 9 at 120,461,421 bp
  • T to C, chromosome 10 at 52,404,072 bp
  • T to C, chromosome 10 at 117,759,176 bp
  • A to T, chromosome 10 at 127,304,302 bp
  • T to A, chromosome 11 at 74,792,237 bp
  • A to T, chromosome 12 at 31,660,717 bp
  • A to T, chromosome 12 at 69,185,384 bp
  • G to A, chromosome 12 at 84,308,346 bp
  • A to T, chromosome 13 at 36,734,264 bp
  • A to T, chromosome 13 at 50,474,460 bp
  • A to G, chromosome 13 at 118,384,565 bp
  • A to T, chromosome 14 at 49,232,946 bp
  • A to G, chromosome 14 at 93,887,048 bp
  • A to T, chromosome 14 at 119,049,426 bp
  • G to T, chromosome 15 at 6,844,453 bp
  • G to T, chromosome 15 at 27,851,933 bp
  • T to A, chromosome 15 at 59,654,602 bp
  • A to G, chromosome 15 at 75,045,608 bp
  • A to G, chromosome 16 at 35,314,091 bp
  • T to C, chromosome 16 at 89,789,186 bp
  • C to T, chromosome 17 at 20,951,346 bp
  • G to A, chromosome 17 at 25,367,134 bp
  • A to G, chromosome 17 at 30,851,630 bp
  • C to A, chromosome 17 at 32,544,142 bp
  • G to A, chromosome 17 at 55,962,030 bp
  • T to A, chromosome 18 at 12,905,081 bp
  • T to A, chromosome 18 at 77,254,782 bp
  • T to C, chromosome 19 at 4,918,357 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5986 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044166-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.