Strain Name:
C57BL/6J-MtgxR6004Btlr
Stock Number:
044182-MU
Citation ID:
RRID:MMRRC_044182-MU
Other Names:
R6004 (G1)
Major Collection:

Gene Information

Pank4
Name: pantothenate kinase 4
Synonyms: D030031I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269614
Homologene: 41235
Nrg4
Name: neuregulin 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83961
Homologene: 12921
Zfp930
Name: zinc finger protein 930
Synonyms: D10627, zinc finger protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234358
Ylpm1
Name: YLP motif containing 1
Synonyms: A930013E17Rik, Zap3, ZAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56531
Homologene: 87707
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103554
Homologene: 113742
Npepps
Name: aminopeptidase puromycin sensitive
Synonyms: Psa, MP100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19155
HGNC: HGNC:7900
Homologene: 36199
Rttn
Name: rotatin
Synonyms: C530033I08Rik, 4921538A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 246102
VEGA: 18
Homologene: 65275
Vps39
Name: VPS39 HOPS complex subunit
Synonyms: A230065P22Rik, Vam6, Vam6P, mVam6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269338
Homologene: 41025
Arntl
Name: aryl hydrocarbon receptor nuclear translocator-like
Synonyms: MOP3, Arnt3, bHLHe5, Bmal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11865
HGNC: HGNC:701
Homologene: 910
Htr1f
Name: 5-hydroxytryptamine (serotonin) receptor 1F
Synonyms: Htr1eb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 15557
VEGA: 16
HGNC: HGNC:5292
Homologene: 37361
Srsf7
Name: serine and arginine-rich splicing factor 7
Synonyms: 9430065L19Rik, Sfrs7, 9G8, NX-96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 225027
VEGA: 17
Homologene: 134446
Acp6
Name: acid phosphatase 6, lysophosphatidic
Synonyms: ACPL1, mPACPL1, 5730559A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66659
Homologene: 41128
Strip2
Name: striatin interacting protein 2
Synonyms: Fam40b, D330017J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320609
Homologene: 66198
Msh3
Name: mutS homolog 3
Synonyms: Rep-3, Rep3, D13Em1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17686
HGNC: HGNC:7326
Homologene: 1829
Prkrip1
Name: Prkr interacting protein 1 (IL11 inducible)
Synonyms: 8430424D23Rik, C114
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66801
Homologene: 6323
Dcaf6
Name: DDB1 and CUL4 associated factor 6
Synonyms: PC326, Iqwd1, 1200006M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74106
Homologene: 10199
Inpp4a
Name: inositol polyphosphate-4-phosphatase, type I
Synonyms: 107kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269180
HGNC: HGNC:6074
Homologene: 2871
Tusc3
Name: tumor suppressor candidate 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 80286
Homologene: 6937
Stag3
Name: stromal antigen 3
Synonyms: stromalin 3, SA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50878
Homologene: 40844
Cars2
Name: cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
Synonyms: 2410044A07Rik, 2310051N18Rik, D530030H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71941
Homologene: 11575
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Myh15
Name: myosin, heavy chain 15
Synonyms: EG667772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 667772
VEGA: 16
Homologene: 18929
Lrrc37a
Name: leucine rich repeat containing 37A
Synonyms: LOC237954
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237954
Homologene: 138824
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Chrd
Name: chordin
Synonyms: Chd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12667
HGNC: HGNC:1949
Homologene: 2774
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100040766
Homologene: 85300
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: V2r16, VR16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22307
Homologene: 129606
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: Orp1, mG145, Dcdc3, oxygen-regulated protein 1, Rp1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19888
Homologene: 4564
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Plce1
Name: phospholipase C, epsilon 1
Synonyms: PLCepsilon, 4933403A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74055
Homologene: 9478
Adam5
Name: a disintegrin and metallopeptidase domain 5
Synonyms: tMDCII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11499
HGNC: HGNC:212
Homologene: 49138
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628870
Homologene: 46008
Zfp712
Name: zinc finger protein 712
Synonyms: 4921504N20Rik, mszf89, mszf31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 78251
VEGA: 13
Homologene: 136296
Trp63
Name: transformation related protein 63
Synonyms: p63, TAp63, KET protein, p73L, p51/p63, deltaNp63, Trp53rp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 22061
Homologene: 31189
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 637908
Homologene: 104040
Speg
Name: SPEG complex locus
Synonyms: SPEGalpha, SPEGbeta, BPEG, SPEG, D1Bwg1450e, Apeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11790
Homologene: 55619
Arl6
Name: ADP-ribosylation factor-like 6
Synonyms: 2210411E14Rik, 1110018H24Rik, BBS3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 56297
Homologene: 12960
Idua
Name: iduronidase, alpha-L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 15932
HGNC: HGNC:5391
Homologene: 170
Raet1d
Name: retinoic acid early transcript delta
Synonyms: RAE-1delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56554
Homologene: 134115
Olfr1016
Name: olfactory receptor 1016
Synonyms: MOR213-9, GA_x6K02T2Q125-47278889-47277960
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257915
Homologene: 83133
Olfr1130
Name: olfactory receptor 1130
Synonyms: MOR264-4, GA_x6K02T2Q125-49112575-49113519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258835
Homologene: 133705
Cyp4a12b
Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13118
Homologene: 134044
Itgax
Name: integrin alpha X
Synonyms: CD11C (p150) alpha polypeptide, Cd11c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Olfr792
Name: olfactory receptor 792
Synonyms: GA_x6K02T2PULF-11219415-11220350, MOR108-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258150
Homologene: 133881
Timm44
Name: translocase of inner mitochondrial membrane 44
Synonyms: Mimt44, Tim44, 0710005E20Rik, D8Ertd118e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21856
Homologene: 4631
Skint11
Name: selection and upkeep of intraepithelial T cells 11
Synonyms: A630098G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230623
Homologene: 136292
Vmn2r50
Name: vomeronasal 2, receptor 50
Synonyms: EG434117
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434117
Homologene: 113703
Olfr890
Name: olfactory receptor 890
Synonyms: MOR162-15_p, MOR162-3, GA_x6K02T2PVTD-31822365-31823309
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258474
Homologene: 138311
Gpx6
Name: glutathione peroxidase 6
Synonyms: 1700020G18Rik, olfactory
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75512
HGNC: HGNC:4558
Homologene: 130008
Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
Synonyms: 2900026H06Rik, E130009M08Rik, PP2A-PR55B, PR55-BETA, 6330404L05Rik, SCA12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72930
HGNC: HGNC:9305
Homologene: 55833
Olfr32
Name: olfactory receptor 32
Synonyms: GA_x6K02T2Q125-51573576-51572650, MTPCR05, MOR227-7P, MOR227-9_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18331
HGNC: HGNC:8290
Homologene: 110550
Mill2
Name: MHC I like leukocyte 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243864
HGNC: HGNC:7091
Homologene: 88329
Olfr1313
Name: olfactory receptor 1313
Synonyms: GA_x6K02T2Q125-73119859-73118924, MOR245-23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258257
Homologene: 106834
Tlnrd1
Name: talin rod domain containing 1
Synonyms: Mesdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 80889
Homologene: 11209
Ighv14-2
Name: immunoglobulin heavy variable 14-2
Synonyms: Gm16683
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 668421
Sgo2b
Name: shugoshin 2B
Synonyms: Sgol2b, Gm4975
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244495
Homologene: 51867
Ighv1-65
Name: immunoglobulin heavy variable V1-65
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 780958
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 4,197,585 bp
  • T to C, chromosome 1 at 37,372,370 bp
  • A to T, chromosome 1 at 75,415,603 bp
  • G to A, chromosome 1 at 88,248,655 bp
  • A to G, chromosome 1 at 165,388,685 bp
  • A to T, chromosome 2 at 85,799,382 bp
  • T to A, chromosome 2 at 87,607,909 bp
  • T to C, chromosome 2 at 90,138,999 bp
  • G to T, chromosome 2 at 112,072,026 bp
  • A to G, chromosome 2 at 120,345,650 bp
  • C to T, chromosome 3 at 97,175,681 bp
  • A to G, chromosome 4 at 114,231,728 bp
  • A to G, chromosome 4 at 115,433,467 bp
  • G to T, chromosome 4 at 154,977,221 bp
  • A to G, chromosome 5 at 108,680,644 bp
  • T to G, chromosome 5 at 108,999,078 bp
  • A to G, chromosome 5 at 136,197,782 bp
  • A to T, chromosome 5 at 138,289,206 bp
  • T to A, chromosome 6 at 29,926,571 bp
  • G to A, chromosome 7 at 10,050,059 bp
  • T to C, chromosome 7 at 12,582,401 bp
  • A to T, chromosome 7 at 18,856,538 bp
  • A to G, chromosome 7 at 83,882,779 bp
  • A to T, chromosome 7 at 113,280,727 bp
  • T to C, chromosome 7 at 120,086,297 bp
  • A to T, chromosome 7 at 128,131,452 bp
  • G to T, chromosome 8 at 4,267,747 bp
  • A to G, chromosome 8 at 11,547,743 bp
  • T to A, chromosome 8 at 24,781,669 bp
  • G to C, chromosome 8 at 39,071,406 bp
  • G to A, chromosome 8 at 63,926,673 bp
  • A to G, chromosome 8 at 69,227,904 bp
  • A to G, chromosome 9 at 38,143,960 bp
  • T to C, chromosome 9 at 55,259,383 bp
  • T to A, chromosome 10 at 22,371,394 bp
  • A to T, chromosome 10 at 27,235,785 bp
  • T to A, chromosome 10 at 107,879,529 bp
  • T to A, chromosome 10 at 129,540,890 bp
  • T to A, chromosome 11 at 30,856,896 bp
  • T to C, chromosome 11 at 97,223,124 bp
  • C to T, chromosome 11 at 103,502,536 bp
  • A to G, chromosome 12 at 84,876,149 bp
  • A to T, chromosome 12 at 85,029,084 bp
  • T to A, chromosome 12 at 113,994,635 bp
  • C to T, chromosome 12 at 115,532,436 bp
  • A to C, chromosome 13 at 21,319,069 bp
  • A to G, chromosome 13 at 67,041,705 bp
  • T to A, chromosome 13 at 92,342,414 bp
  • T to C, chromosome 16 at 20,735,237 bp
  • T to C, chromosome 16 at 25,763,396 bp
  • A to T, chromosome 16 at 49,159,699 bp
  • A to T, chromosome 16 at 59,623,894 bp
  • T to C, chromosome 16 at 64,925,876 bp
  • A to T, chromosome 17 at 80,205,853 bp
  • T to C, chromosome 18 at 43,059,159 bp
  • T to C, chromosome 18 at 89,021,692 bp
  • A to G, chromosome 19 at 38,721,871 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6004 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044182-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.