Strain Name:
C57BL/6J-MtgxR6024Btlr
Stock Number:
044196-MU
Citation ID:
RRID:MMRRC_044196-MU
Other Names:
R6024 (G1)
Major Collection:

Gene Information

Itga6
Name: integrin alpha 6
Synonyms: Cd49f, 5033401O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16403
HGNC: HGNC:6142
Homologene: 20091
Ptpn3
Name: protein tyrosine phosphatase, non-receptor type 3
Synonyms: PTP-H1, PTPCL, 9530011I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545622
HGNC: HGNC:9655
Homologene: 74451
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Pcnt
Name: pericentrin (kendrin)
Synonyms: m239Asp, m275Asp, Pcnt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18541
VEGA: 10
Trappc8
Name: trafficking protein particle complex 8
Synonyms: Trs85, 5033403J15Rik, D030074E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75964
VEGA: 18
Homologene: 40993
R3hdm2
Name: R3H domain containing 2
Synonyms: 1300003K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71750
Homologene: 8954
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 3526402J09Rik, 5730590C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77097
Homologene: 64680
Cog4
Name: component of oligomeric golgi complex 4
Synonyms: D8Ertd515e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102339
Homologene: 7155
Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
Synonyms: MRCKgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240505
Homologene: 28384
Myo9a
Name: myosin IXa
Synonyms: C130068I12Rik, 4732465J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101471
Homologene: 16377
Ebf3
Name: early B cell factor 3
Synonyms: 3110018A08Rik, O/E-2, Olf-1/EBF-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13593
Homologene: 56472
Avpr1a
Name: arginine vasopressin receptor 1A
Synonyms: V1aR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54140
HGNC: HGNC:895
Homologene: 568
Muc16
Name: mucin 16
Synonyms: Gm21044, 1110008I14Rik, LOC385009
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73732
Homologene: 141193
Nxf1
Name: nuclear RNA export factor 1
Synonyms: TAP, Mex67, Mvb1, Tip associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 53319
HGNC: HGNC:8071
Homologene: 38176
Wdr4
Name: WD repeat domain 4
Synonyms: Wh, D530049K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57773
Homologene: 32422
Dpy19l4
Name: dpy-19-like 4 (C. elegans)
Synonyms: Narg3, LOC381510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381510
Homologene: 18773
Mst1r
Name: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Synonyms: PTK8, Fv-2, Fv2, STK, friend virus susceptibility 2, CDw136, Ron
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19882
HGNC: HGNC:7381
Homologene: 1835
Usf3
Name: upstream transcription factor family member 3
Synonyms: Gm608, LOC385650, LOC207806, 5530400K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Nkx2-2
Name: NK2 homeobox 2
Synonyms: Nkx2.2, tinman, Nkx-2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18088
HGNC: HGNC:7835
Homologene: 1879
Ttn
Name: titin
Synonyms: L56, 2310074I15Rik, 2310036G12Rik, 1100001C23Rik, connectin, shru, D830007G01Rik, mdm, D330041I19Rik, 2310057K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: Dnahc11, avc4, b2b598Clo, lrd, b2b1289Clo, b2b1727Clo, b2b1279Clo, b2b1203Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Ccdc84
Name: coiled-coil domain containing 84
Synonyms: D630044F24Rik, LOC382073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382073
VEGA: 9
Homologene: 13886
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: SM2, SM1, smMHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, Gpr98, Mass1, VLGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Fbn2
Name: fibrillin 2
Synonyms: sy, Fib-2, Sne
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: Misshapen/NIKs-related kinase, Ysk2, Map4k6, MINK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50932
Homologene: 56762
Csf3r
Name: colony stimulating factor 3 receptor (granulocyte)
Synonyms: Csfgr, G-CSFR, Cd114
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12986
HGNC: HGNC:2439
Homologene: 601
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238455
Homologene: 18813
Ifit1bl2
Name: interferon induced protein with tetratricopeptide repeats 1B like 2
Synonyms: 2010002M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 112419
Homologene: 78213
Syt11
Name: synaptotagmin XI
Synonyms: 6530420C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229521
Homologene: 23120
Skint3
Name: selection and upkeep of intraepithelial T cells 3
Synonyms: A430090E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 195564
Arhgef5
Name: Rho guanine nucleotide exchange factor (GEF) 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54324
Homologene: 66300
Gcc1
Name: golgi coiled coil 1
Synonyms: 4932417P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74375
Homologene: 11567
Unc5d
Name: unc-5 netrin receptor D
Synonyms: Unc5h4, D930029E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 210801
Homologene: 15450
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210274
Homologene: 105965
Dnaic2
Name: dynein, axonemal, intermediate chain 2
Synonyms: C030015H18Rik, b2b3405Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432611
Homologene: 11311
Pygl
Name: liver glycogen phosphorylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110095
HGNC: HGNC:9725
Homologene: 84371
Nrxn1
Name: neurexin I
Synonyms: neurexin I alpha, 1700062G21Rik, A230068P09Rik, 9330127H16Rik, neurexin I alpha, neurexin I alpha, neurexin I beta, neurexin I beta, neurexin I beta, alpha-latrotoxin receptor (calcium-dependent)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Mctp1
Name: multiple C2 domains, transmembrane 1
Synonyms: 2810465F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78771
Homologene: 75211
Akr1d1
Name: aldo-keto reductase family 1, member D1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 208665
HGNC: HGNC:388
Homologene: 55943
Hmgcl
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15356
HGNC: HGNC:5005
Homologene: 159
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: 4631429H07Rik, 1110007I12Rik, Clip 170, cytoplasmic linker protein 50, Clip50, restin, Rsn, CLIP-170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56430
Homologene: 74455
Doxl2
Name: diamine oxidase-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243376
Homologene: 19443
Gm1527
Name: predicted gene 1527
Synonyms: LOC385263
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 385263
Homologene: 133976
Gm4846
Name: predicted gene 4846
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226601
Homologene: 136281
Gm340
Name: predicted gene 340
Synonyms: LOC381224
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Slco5a1
Name: solute carrier organic anion transporter family, member 5A1
Synonyms: A630033C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240726
Homologene: 57135
Sesn1
Name: sestrin 1
Synonyms: PA26, 1110002G11Rik, SEST1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 140742
Homologene: 8697
Creb3l4
Name: cAMP responsive element binding protein 3-like 4
Synonyms: 1700012K17Rik, Tisp40alpha, Tisp40, Tisp40beta, ATCE1, JAL, 5330432F22Rik, mJAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 78284
Homologene: 12693
Nkain2
Name: Na+/K+ transporting ATPase interacting 2
Synonyms: Tcba1, 6330571D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432450
Homologene: 65073
Art2b
Name: ADP-ribosyltransferase 2b
Synonyms: Rt-6, Rt6, Rt6-2, ART2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11872
Homologene: 113756
Tmem200c
Name: transmembrane protein 200C
Synonyms: Gm6338
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 622645
VEGA: 17
Homologene: 78765
Wdr49
Name: WD repeat domain 49
Synonyms: EG213248
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213248
Homologene: 18714
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 12,944,070 bp
  • T to C, chromosome 1 at 30,863,226 bp
  • T to A, chromosome 1 at 166,490,127 bp
  • A to G, chromosome 2 at 71,787,233 bp
  • A to G, chromosome 2 at 76,814,143 bp
  • T to A, chromosome 2 at 147,184,041 bp
  • C to T, chromosome 3 at 28,920,603 bp
  • T to G, chromosome 3 at 75,301,826 bp
  • A to G, chromosome 3 at 88,762,109 bp
  • G to A, chromosome 3 at 90,238,699 bp
  • A to T, chromosome 4 at 11,276,876 bp
  • C to A, chromosome 4 at 57,248,653 bp
  • T to C, chromosome 4 at 112,290,346 bp
  • C to A, chromosome 4 at 126,037,517 bp
  • T to C, chromosome 4 at 135,955,615 bp
  • T to C, chromosome 5 at 123,615,089 bp
  • T to C, chromosome 6 at 28,419,300 bp
  • T to C, chromosome 6 at 37,558,482 bp
  • T to C, chromosome 6 at 43,275,134 bp
  • A to T, chromosome 6 at 48,976,096 bp
  • A to G, chromosome 7 at 101,580,380 bp
  • T to C, chromosome 7 at 137,200,535 bp
  • T to C, chromosome 7 at 141,258,985 bp
  • T to A, chromosome 7 at 141,641,574 bp
  • C to T, chromosome 7 at 144,180,031 bp
  • A to G, chromosome 8 at 28,875,511 bp
  • C to T, chromosome 8 at 110,881,480 bp
  • A to T, chromosome 9 at 18,646,671 bp
  • T to C, chromosome 9 at 44,417,952 bp
  • A to G, chromosome 9 at 59,855,388 bp
  • T to A, chromosome 9 at 107,908,151 bp
  • A to T, chromosome 10 at 31,951,285 bp
  • A to T, chromosome 10 at 41,896,200 bp
  • T to C, chromosome 10 at 76,420,037 bp
  • A to G, chromosome 10 at 122,449,148 bp
  • T to A, chromosome 10 at 127,459,480 bp
  • A to G, chromosome 11 at 70,599,089 bp
  • G to A, chromosome 11 at 105,867,717 bp
  • T to C, chromosome 11 at 105,923,672 bp
  • A to T, chromosome 11 at 114,752,908 bp
  • T to C, chromosome 12 at 70,197,067 bp
  • G to T, chromosome 12 at 118,030,272 bp
  • T to C, chromosome 12 at 119,450,425 bp
  • G to T, chromosome 13 at 76,385,161 bp
  • A to G, chromosome 13 at 81,476,505 bp
  • T to A, chromosome 16 at 14,277,703 bp
  • A to T, chromosome 16 at 44,219,840 bp
  • A to T, chromosome 17 at 31,501,298 bp
  • A to C, chromosome 17 at 68,841,727 bp
  • T to C, chromosome 17 at 90,590,098 bp
  • A to G, chromosome 18 at 20,833,009 bp
  • A to G, chromosome 18 at 58,076,836 bp
  • T to A, chromosome 19 at 6,317,496 bp
  • C to T, chromosome 19 at 8,767,744 bp
  • G to T, chromosome 19 at 34,620,038 bp
  • C to A, chromosome 19 at 41,583,957 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6024 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044196-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.