Strain Name:
C57BL/6J-MtgxR6032Btlr
Stock Number:
044204-MU
Citation ID:
RRID:MMRRC_044204-MU
Other Names:
R6032 (G1)
Major Collection:

Gene Information

Tle4
Name: transducin-like enhancer of split 4
Synonyms: Grg4, ESTM14, 5730411M05Rik, ESTM13, Bce1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21888
VEGA: 19
Homologene: 38259
Dnajc3
Name: DnaJ heat shock protein family (Hsp40) member C3
Synonyms: mp58, Dnajc3, Dnajc3a, Dnajc3b, Prkri, p58IPK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100037258
VEGA: 14
HGNC: HGNC:9439
Homologene: 2486
Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: A230020K14Rik, N-CoR, 5730405M06Rik, Rxrip13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: rcw, nmf373, 4930455H15Rik, mGluR1, Grm1, Gprc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Wsb1
Name: WD repeat and SOCS box-containing 1
Synonyms: 2700038M07Rik, 1110056B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78889
Homologene: 9218
Kcns2
Name: K+ voltage-gated channel, subfamily S, 2
Synonyms: E130006J24Rik, Kv9.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16539
VEGA: 15
HGNC: HGNC:6301
Homologene: 22465
Nrxn2
Name: neurexin II
Synonyms: neurexin II alpha, neurexin II beta, 6430591O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18190
HGNC: HGNC:8009
Homologene: 86984
Mef2c
Name: myocyte enhancer factor 2C
Synonyms: 5430401D19Rik, 9930028G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17260
HGNC: HGNC:6996
Homologene: 31087
Prmt1
Name: protein arginine N-methyltransferase 1
Synonyms: 6720434D09Rik, Hrmt1l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15469
HGNC: HGNC:5187
Homologene: 21477
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: B630009I04Rik, Helic1, ASC1p200
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 2900005P22Rik, Nibp, 1810044A24Rik, TRS130, 4632408O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Supt5
Name: suppressor of Ty 5, DSIF elongation factor subunit
Synonyms: Supt5h, Spt5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20924
Homologene: 2384
Zfp106
Name: zinc finger protein 106
Synonyms: Sh3bp3, Cd-1, H3a, sirm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20402
Homologene: 40787
Atp6v1a
Name: ATPase, H+ transporting, lysosomal V1 subunit A
Synonyms: VA68, Atp6a1, VPP2, lysosomal 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11964
HGNC: HGNC:851
Homologene: 123934
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Aplp2
Name: amyloid beta (A4) precursor-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11804
VEGA: 9
HGNC: HGNC:598
Homologene: 20396
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Cyhr1
Name: cysteine and histidine rich 1
Synonyms: 1110031M01Rik, Chrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54151
Homologene: 32791
Fbxl19
Name: F-box and leucine-rich repeat protein 19
Synonyms: Fbl19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233902
Homologene: 129692
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Rel
Name: reticuloendotheliosis oncogene
Synonyms: c-Rel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19696
HGNC: HGNC:9954
Homologene: 2182
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: eNOS, 2310065A03Rik, Nos-3, ecNOS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, LOC245827, EMI2, mKIAA0811
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Fam184b
Name: family with sequence similarity 184, member B
Synonyms: 9630031F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 58227
Homologene: 137353
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240411
Pramel13
Name: PRAME like 13
Synonyms: Pramef12, 4930569K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77632
Homologene: 135701
Tbx15
Name: T-box 15
Synonyms: Tbx8, Tbx14, de
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21384
Homologene: 7967
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Slx4
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Synonyms: Btbd12, D16Bwg1016e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 52864
Homologene: 23770
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: BC048546, Ovos2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232400
Homologene: 45969
Gsdme
Name: gasdermin E
Synonyms: 2310037D07Rik, Fin15, 4932441K13Rik, Dfna5h, Dfna5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54722
HGNC: HGNC:2810
Homologene: 3242
Crybg1
Name: crystallin beta-gamma domain containing 1
Synonyms: Aim1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11630
HGNC: HGNC:356
Homologene: 18168
Aoc2
Name: amine oxidase, copper containing 2 (retina-specific)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237940
HGNC: HGNC:549
Homologene: 56457
Rpap2
Name: RNA polymerase II associated protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231571
Homologene: 11733
Smc1b
Name: structural maintenance of chromosomes 1B
Synonyms: Smc1l2, SMC1beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 140557
VEGA: 15
Homologene: 13786
Trim10
Name: tripartite motif-containing 10
Synonyms: Rnf9, Herf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19824
Homologene: 4932
Aldh8a1
Name: aldehyde dehydrogenase 8 family, member A1
Synonyms: RALDH4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237320
Homologene: 23369
Ppef2
Name: protein phosphatase, EF hand calcium-binding domain 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19023
HGNC: HGNC:9244
Homologene: 55959
Postn
Name: periostin, osteoblast specific factor
Synonyms: A630052E07Rik, peri, OSF-2, Periostin, Osf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50706
Homologene: 4730
Daam2
Name: dishevelled associated activator of morphogenesis 2
Synonyms: 2310016D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76441
VEGA: 17
Homologene: 69186
Shisa9
Name: shisa family member 9
Synonyms: 2700045P11Rik, CKAMP44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72555
Homologene: 109462
Adamdec1
Name: ADAM-like, decysin 1
Synonyms: Dcsn, 2210414L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 58860
VEGA: 14
Homologene: 8711
Pfpl
Name: pore forming protein-like
Synonyms: Epcs50, Epcs5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Gpatch3
Name: G patch domain containing 3
Synonyms: Gpatc3, D930035B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242691
Homologene: 11122
4930505A04Rik
Name: RIKEN cDNA 4930505A04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75087
Homologene: 18988
Bag4
Name: BCL2-associated athanogene 4
Synonyms: 2410112I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67384
HGNC: HGNC:940
Homologene: 31270
Cyp3a44
Name: cytochrome P450, family 3, subfamily a, polypeptide 44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 337924
HGNC: HGNC:2638
Homologene: 133568
Olfr146
Name: olfactory receptor 146
Synonyms: MOR171-10, GA_x6K02T2PVTD-32715386-32714466, M15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258742
VEGA: 9
Ifnlr1
Name: interferon lambda receptor 1
Synonyms: IFNLR1, CRF2-12, Il28ra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242700
Homologene: 52086
Olfr1535
Name: olfactory receptor 1535
Synonyms: MOR256-63, GA_x6K02T2QHY8-11688984-11689964, MOR256-36, MOR256-36, Olfr1365
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 404335
Homologene: 131356
Olfr1289
Name: olfactory receptor 1289
Synonyms: GA_x6K02T2Q125-72534883-72535821, MOR245-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258399
HGNC: HGNC:8301
Slc25a10
Name: solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
Synonyms: Dic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27376
Homologene: 6519
Gm3454
Name: predicted gene 3454
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 100041652
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 2 at 13,325,184 bp
  • T to C, chromosome 2 at 111,483,850 bp
  • T to C, chromosome 2 at 120,535,393 bp
  • A to T, chromosome 3 at 54,376,716 bp
  • T to C, chromosome 3 at 99,352,517 bp
  • A to G, chromosome 4 at 133,578,306 bp
  • A to G, chromosome 4 at 135,705,626 bp
  • A to C, chromosome 4 at 144,393,028 bp
  • A to T, chromosome 5 at 24,379,811 bp
  • G to A, chromosome 5 at 45,582,896 bp
  • A to G, chromosome 5 at 92,230,524 bp
  • A to C, chromosome 5 at 107,597,795 bp
  • G to T, chromosome 5 at 145,777,946 bp
  • T to A, chromosome 6 at 50,245,954 bp
  • T to A, chromosome 6 at 128,549,836 bp
  • T to C, chromosome 7 at 28,316,175 bp
  • A to G, chromosome 7 at 44,977,102 bp
  • C to T, chromosome 7 at 127,761,265 bp
  • T to C, chromosome 8 at 25,777,493 bp
  • C to T, chromosome 9 at 31,150,944 bp
  • A to G, chromosome 9 at 39,018,965 bp
  • A to T, chromosome 10 at 10,719,805 bp
  • T to C, chromosome 10 at 21,389,071 bp
  • A to G, chromosome 10 at 43,956,760 bp
  • C to T, chromosome 10 at 50,842,183 bp
  • G to T, chromosome 11 at 9,297,752 bp
  • A to G, chromosome 11 at 23,742,684 bp
  • C to T, chromosome 11 at 30,426,349 bp
  • G to C, chromosome 11 at 55,253,934 bp
  • A to T, chromosome 11 at 62,373,321 bp
  • T to C, chromosome 11 at 79,240,199 bp
  • G to A, chromosome 11 at 101,325,801 bp
  • A to T, chromosome 11 at 120,494,958 bp
  • A to G, chromosome 12 at 7,995,513 bp
  • G to T, chromosome 13 at 21,555,907 bp
  • A to T, chromosome 13 at 83,662,359 bp
  • T to C, chromosome 14 at 68,579,184 bp
  • T to C, chromosome 14 at 118,968,031 bp
  • T to C, chromosome 15 at 34,838,934 bp
  • T to C, chromosome 15 at 72,925,530 bp
  • T to A, chromosome 15 at 75,311,599 bp
  • C to T, chromosome 15 at 76,658,858 bp
  • A to T, chromosome 15 at 85,066,229 bp
  • A to T, chromosome 16 at 3,980,157 bp
  • T to C, chromosome 16 at 11,984,908 bp
  • T to C, chromosome 16 at 44,106,940 bp
  • A to G, chromosome 16 at 96,649,991 bp
  • A to T, chromosome 17 at 36,871,714 bp
  • A to C, chromosome 17 at 49,486,497 bp
  • A to G, chromosome 17 at 67,750,643 bp
  • C to T, chromosome 18 at 3,267,673 bp
  • G to A, chromosome 18 at 77,381,558 bp
  • A to T, chromosome 19 at 6,517,132 bp
  • A to G, chromosome 19 at 12,429,383 bp
  • T to C, chromosome 19 at 14,452,108 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6032 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044204-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.