Strain Name:
C57BL/6J-MtgxR6042Btlr
Stock Number:
044210-MU
Citation ID:
RRID:MMRRC_044210-MU
Other Names:
R6042 (G1)
Major Collection:

Gene Information

Col2a1
Name: collagen, type II, alpha 1
Synonyms: M100413, Del1, Rgsc856, Col2, Lpk, Col2a-1, M100856, Col2a, Rgsc413
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12824
HGNC: HGNC:2200
Homologene: 55607
Htr3a
Name: 5-hydroxytryptamine (serotonin) receptor 3A
Synonyms: 5-HT3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15561
VEGA: 9
HGNC: HGNC:5297
Homologene: 671
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11287
Homologene: 104112
Rgs7
Name: regulator of G protein signaling 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 24012
Homologene: 2193
Dst
Name: dystonin
Synonyms: ah, athetoid, nmf203, Bpag1, nmf339, A830042E19Rik, bullous pemphigoid antigen 1, Macf2, BPAG1, BPAG1-n, bullous pemphigoid antigen 1, Bpag, 2310001O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224273
Homologene: 28544
Tacr3
Name: tachykinin receptor 3
Synonyms: neuromedin K receptor, Nk3r, Tac3r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21338
Homologene: 824
Helz
Name: helicase with zinc finger domain
Synonyms: 9430093I07Rik, 9630002H22Rik, 3110078M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78455
Homologene: 8918
Smchd1
Name: SMC hinge domain containing 1
Synonyms: MommeD1, 4931400A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74355
Homologene: 23665
Uqcc1
Name: ubiquinol-cytochrome c reductase complex assembly factor 1
Synonyms: Cbp3, 3110038N19Rik, 2310079L17Rik, mbFZb, Uqcc, Bfzp, 2410003P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56046
Homologene: 14709
Actn1
Name: actinin, alpha 1
Synonyms: 3110023F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109711
VEGA: 12
HGNC: HGNC:163
Homologene: 55553
Xpo7
Name: exportin 7
Synonyms: Ranbp16, 4930506C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 65246
VEGA: 14
Homologene: 22857
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Zfp442
Name: zinc finger protein 442
Synonyms: OTTMUSG00000015730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668923
Homologene: 136215
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215113
Homologene: 17555
Cnr1
Name: cannabinoid receptor 1 (brain)
Synonyms: CB1, CB1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12801
HGNC: HGNC:2159
Homologene: 7273
Nectin2
Name: nectin cell adhesion molecule 2
Synonyms: nectin-2, MPH, Pvrl2, Cd112, Pvs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19294
HGNC: HGNC:9707
Homologene: 86092
Rras
Name: related RAS viral (r-ras) oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20130
Homologene: 4565
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Sqstm1
Name: sequestosome 1
Synonyms: Osi, p62, A170, STAP, OSF-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18412
Homologene: 31202
Snrnp27
Name: small nuclear ribonucleoprotein 27 (U4/U6.U5)
Synonyms: 2610209M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66618
Homologene: 135794
Pcdh12
Name: protocadherin 12
Synonyms: vascular endothelial cadherin-2, VE-cadherin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53601
HGNC: HGNC:8657
Homologene: 9574
Stk32b
Name: serine/threonine kinase 32B
Synonyms: STKG6, Stk32, YANK2, 2510009F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64293
Homologene: 48654
Esrp1
Name: epithelial splicing regulatory protein 1
Synonyms: 2210008M09Rik, Rbm35a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 207920
Homologene: 9785
Olig3
Name: oligodendrocyte transcription factor 3
Synonyms: bHLHe20, Bhlhb7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 94222
VEGA: 10
Homologene: 14201
Gcgr
Name: glucagon receptor
Synonyms: GR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14527
HGNC: HGNC:4192
Homologene: 131
Barx2
Name: BarH-like homeobox 2
Synonyms: Barx2b, 2310006E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12023
HGNC: HGNC:956
Homologene: 2715
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC382129, 9430076A06Rik, D430038H04Rik, LOC234973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Ctsb
Name: cathepsin B
Synonyms: CB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13030
VEGA: 14
HGNC: HGNC:2527
Homologene: 37550
Lama3
Name: laminin, alpha 3
Synonyms: [a]3B, nicein, 150kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Cdh7
Name: cadherin 7, type 2
Synonyms: CDH7L1, 9330156F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241201
HGNC: HGNC:1766
Homologene: 68391
Ankar
Name: ankyrin and armadillo repeat containing
Synonyms: 4932422E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 319695
Homologene: 85163
Vmn1r20
Name: vomeronasal 1 receptor 20
Synonyms: Gm5569
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434017
Homologene: 79462
Micalcl
Name: MICAL C-terminal like
Synonyms: Ebitein1, 4921517J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100504195
Homologene: 13149
Sdcbp2
Name: syndecan binding protein (syntenin) 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228765
Homologene: 9240
Syt16
Name: synaptotagmin XVI
Synonyms: Strep14, Syt14l, syt14r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238266
VEGA: 12
Homologene: 12902
Fbxw24
Name: F-box and WD-40 domain protein 24
Synonyms: Gm5162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382106
Homologene: 110776
Cntnap5b
Name: contactin associated protein-like 5B
Synonyms: Caspr5-2, C230078M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241175
Homologene: 104295
Syt10
Name: synaptotagmin X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54526
Homologene: 10303
Gm13101
Name: predicted gene 13101
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 626922
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: E030045D18Rik, Krc, Schnurri-3, Shn3, 2900056N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16656
Homologene: 7803
Zswim5
Name: zinc finger SWIM-type containing 5
Synonyms: 4933426E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74464
Homologene: 18958
Olfr1431
Name: olfactory receptor 1431
Synonyms: GA_x6K02T2RE5P-2573738-2574676, MOR214-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258409
Homologene: 115495
Mgat5
Name: mannoside acetylglucosaminyltransferase 5
Synonyms: GlcNAc-TV, beta1,6N-acetylglucosaminyltransferase V, 5330407H02Rik, 4930471A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107895
HGNC: HGNC:7049
Homologene: 1808
Olfr887
Name: olfactory receptor 887
Synonyms: MOR162-5, GA_x6K02T2PVTD-31764095-31765024
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258415
Homologene: 133625
Fpr-rs7
Name: formyl peptide receptor, related sequence 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 321021
Phpt1
Name: phosphohistidine phosphatase 1
Synonyms: 1700008C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75454
Homologene: 8573
Dcpp2
Name: demilune cell and parotid protein 2
Synonyms: EG630537
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 630537
VEGA: 17
Homologene: 103921
Polr2m
Name: polymerase (RNA) II (DNA directed) polypeptide M
Synonyms: Grinl1a, D9Wsu138e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 28015
Homologene: 9181
Cyp2a22
Name: cytochrome P450, family 2, subfamily a, polypeptide 22
Synonyms: EG233005
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233005
Homologene: 69128
Grifin
Name: galectin-related inter-fiber protein
Synonyms: E130101O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77998
HGNC: HGNC:4577
Homologene: 14293
RP23-399J5.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,188,972 bp
  • G to T, chromosome 1 at 72,674,054 bp
  • G to A, chromosome 1 at 100,390,592 bp
  • A to T, chromosome 1 at 110,138,267 bp
  • T to A, chromosome 1 at 127,459,899 bp
  • G to T, chromosome 1 at 175,149,660 bp
  • T to A, chromosome 2 at 25,574,839 bp
  • T to C, chromosome 2 at 150,408,096 bp
  • T to A, chromosome 2 at 151,582,726 bp
  • G to T, chromosome 2 at 155,921,644 bp
  • A to T, chromosome 3 at 134,932,392 bp
  • T to C, chromosome 4 at 11,357,580 bp
  • T to C, chromosome 4 at 33,944,751 bp
  • A to C, chromosome 4 at 116,962,621 bp
  • C to G, chromosome 4 at 120,097,864 bp
  • G to T, chromosome 4 at 143,966,061 bp
  • T to A, chromosome 5 at 37,649,114 bp
  • C to A, chromosome 5 at 140,563,556 bp
  • T to C, chromosome 6 at 57,432,406 bp
  • A to C, chromosome 6 at 86,682,920 bp
  • A to G, chromosome 6 at 128,524,014 bp
  • C to T, chromosome 7 at 19,738,138 bp
  • A to C, chromosome 7 at 26,934,239 bp
  • A to T, chromosome 7 at 45,020,396 bp
  • A to G, chromosome 7 at 112,380,412 bp
  • T to C, chromosome 8 at 71,089,927 bp
  • T to A, chromosome 9 at 16,377,817 bp
  • C to A, chromosome 9 at 31,846,903 bp
  • T to A, chromosome 9 at 38,085,094 bp
  • T to A, chromosome 9 at 48,904,699 bp
  • T to C, chromosome 9 at 71,483,798 bp
  • T to A, chromosome 9 at 109,607,011 bp
  • T to C, chromosome 10 at 19,356,755 bp
  • A to C, chromosome 11 at 50,207,424 bp
  • T to C, chromosome 11 at 75,570,607 bp
  • T to C, chromosome 11 at 107,614,120 bp
  • T to C, chromosome 11 at 120,534,758 bp
  • T to C, chromosome 12 at 74,266,730 bp
  • T to A, chromosome 12 at 80,177,249 bp
  • G to T, chromosome 14 at 63,141,856 bp
  • T to A, chromosome 14 at 70,695,663 bp
  • G to A, chromosome 15 at 66,683,993 bp
  • G to A, chromosome 15 at 89,841,621 bp
  • T to A, chromosome 15 at 98,000,570 bp
  • C to T, chromosome 16 at 59,550,475 bp
  • T to A, chromosome 17 at 20,113,215 bp
  • T to C, chromosome 17 at 23,898,912 bp
  • G to T, chromosome 17 at 30,747,265 bp
  • T to A, chromosome 17 at 71,377,057 bp
  • T to A, chromosome 18 at 12,574,254 bp
  • T to C, chromosome 18 at 38,281,505 bp
  • A to T, chromosome 19 at 12,209,922 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6042 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044210-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.