Strain Name:
C57BL/6J-MtgxR6065Btlr
Stock Number:
044229-MU
Citation ID:
RRID:MMRRC_044229-MU
Other Names:
R6065 (G1)
Major Collection:

Gene Information

Ptprk
Name: protein tyrosine phosphatase, receptor type, K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: NBC3, E430014N10Rik, NBCn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Aff1
Name: AF4/FMR2 family, member 1
Synonyms: Af4, 9630032B01Rik, Rob, Mllt2h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17355
HGNC: HGNC:7135
Homologene: 4340
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 5730405K23Rik, 4921511H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207932
Homologene: 45941
Rspry1
Name: ring finger and SPRY domain containing 1
Synonyms: 4930470D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67610
Homologene: 12164
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: Garnl1, Tulip1, 4930400K19Rik, 2310003F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: LOC381562, D930005K06Rik, Zubr1, A930005E13Rik, p600, 1810009A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69116
Homologene: 10804
Syt2
Name: synaptotagmin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20980
Homologene: 22516
Sec13
Name: SEC13 homolog, nuclear pore and COPII coat complex component
Synonyms: 1110003H02Rik, Sec13l1, Sec13r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 110379
Homologene: 6479
Nop2
Name: NOP2 nucleolar protein
Synonyms: 120kDa, Nol1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 110109
HGNC: HGNC:7867
Homologene: 135865
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225115
Homologene: 25090
BC055324
Name: cDNA sequence BC055324
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381306
Homologene: 10058
Wdr19
Name: WD repeat domain 19
Synonyms: C330027H04Rik, D330023L08Rik, DYF2, Ift144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 213081
Homologene: 11842
Slc35e2
Name: solute carrier family 35, member E2
Synonyms: A530082C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320541
Homologene: 84987
Mycbpap
Name: MYCBP associated protein
Synonyms: AMAP-1, 4932408B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104601
Homologene: 49982
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1565Clo, b2b1537Clo, Dnahc5, Mdnah5, b2b1154Clo, b2b1134Clo, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Chsy3
Name: chondroitin sulfate synthase 3
Synonyms: 4833446K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 78923
VEGA: 18
Homologene: 28624
Lama3
Name: laminin, alpha 3
Synonyms: [a]3B, nicein, 150kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Tm7sf2
Name: transmembrane 7 superfamily member 2
Synonyms: 3110041O18Rik, ANG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 73166
Homologene: 68305
Rab3d
Name: RAB3D, member RAS oncogene family
Synonyms: C130057E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19340
HGNC: HGNC:9779
Homologene: 20902
Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Synonyms: GluN2A, GluRepsilon1, NR2A, NMDAR2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14811
HGNC: HGNC:4585
Homologene: 645
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: ephexin, Tims2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
Vmn2r82
Name: vomeronasal 2, receptor 82
Synonyms: EG624845
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 624845
Homologene: 83483
Fcnb
Name: ficolin B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14134
Homologene: 1518
Myo18b
Name: myosin XVIIIb
Synonyms: 4933411E19Rik, 4932408L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74376
Homologene: 53435
Fbxw15
Name: F-box and WD-40 domain protein 15
Synonyms: Fbxo12J
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382105
Homologene: 110776
Kcnj12
Name: potassium inwardly-rectifying channel, subfamily J, member 12
Synonyms: MB-IRK2, IRK2, Kir2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16515
HGNC: HGNC:6258
Homologene: 7793
Cd300ld2
Name: CD300 molecule like family member D2
Synonyms: Gm11709
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 629970
Prl7b1
Name: prolactin family 7, subfamily b, member 1
Synonyms: Prlpn, 1600014J19Rik, PLP-N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75596
Homologene: 17809
Ccdc87
Name: coiled-coil domain containing 87
Synonyms: 4931419P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 399599
VEGA: 19
Homologene: 49531
Pcdhgc3
Name: protocadherin gamma subfamily C, 3
Synonyms: PC43, Pcdh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93706
HGNC: HGNC:8716
Homologene: 31099
Gm3453
Name: predicted gene 3453
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Homologene: 115686
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 54,263,599 bp
  • T to A, chromosome 1 at 87,477,648 bp
  • A to G, chromosome 1 at 134,747,557 bp
  • C to T, chromosome 1 at 150,770,330 bp
  • A to T, chromosome 1 at 163,959,388 bp
  • A to G, chromosome 1 at 163,987,688 bp
  • A to C, chromosome 2 at 28,079,910 bp
  • T to G, chromosome 4 at 139,421,238 bp
  • C to T, chromosome 4 at 155,610,026 bp
  • A to G, chromosome 5 at 65,221,713 bp
  • T to C, chromosome 5 at 103,842,252 bp
  • A to G, chromosome 5 at 112,692,781 bp
  • G to T, chromosome 6 at 113,730,832 bp
  • A to G, chromosome 6 at 125,144,565 bp
  • T to C, chromosome 7 at 105,755,421 bp
  • T to C, chromosome 8 at 94,622,987 bp
  • T to C, chromosome 9 at 21,910,519 bp
  • T to A, chromosome 9 at 109,568,178 bp
  • C to T, chromosome 10 at 28,475,170 bp
  • A to G, chromosome 10 at 79,385,376 bp
  • C to T, chromosome 11 at 61,069,877 bp
  • T to C, chromosome 11 at 65,855,338 bp
  • A to G, chromosome 11 at 66,145,397 bp
  • T to C, chromosome 11 at 94,508,187 bp
  • G to A, chromosome 11 at 115,012,602 bp
  • A to G, chromosome 12 at 55,757,924 bp
  • T to C, chromosome 13 at 27,604,546 bp
  • T to C, chromosome 14 at 5,978,233 bp
  • C to A, chromosome 14 at 14,739,836 bp
  • A to T, chromosome 15 at 28,230,468 bp
  • T to C, chromosome 16 at 9,761,907 bp
  • A to G, chromosome 16 at 90,803,332 bp
  • T to G, chromosome 18 at 5,106,724 bp
  • T to C, chromosome 18 at 12,469,928 bp
  • A to G, chromosome 18 at 37,807,676 bp
  • GT to G, chromosome 18 at 59,176,166 bp
  • A to T, chromosome 19 at 4,841,240 bp
  • A to G, chromosome 19 at 6,063,386 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6065 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044229-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.