Strain Name:
C57BL/6J-MtgxR6082Btlr
Stock Number:
044241-MU
Citation ID:
RRID:MMRRC_044241-MU
Other Names:
R6082 (G1)
Major Collection:

Gene Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: FAK, Fadk, FRNK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Eif4e2
Name: eukaryotic translation initiation factor 4E member 2
Synonyms: 2700069E09Rik, Eif4el3, D0H0S6743E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 26987
HGNC: HGNC:3293
Homologene: 128466
Ltbp4
Name: latent transforming growth factor beta binding protein 4
Synonyms: 2310046A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 108075
HGNC: HGNC:6717
Homologene: 2645
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107182
Homologene: 31978
Ptpn11
Name: protein tyrosine phosphatase, non-receptor type 11
Synonyms: 2700084A17Rik, SHP-2, Shp2, SH2 domain-containing protein tyrosine phosphatase-2, SH-PTP2, Syp, PTP2C, PTP1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19247
HGNC: HGNC:9644
Homologene: 2122
Smchd1
Name: SMC hinge domain containing 1
Synonyms: MommeD1, 4931400A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74355
Homologene: 23665
Eif3a
Name: eukaryotic translation initiation factor 3, subunit A
Synonyms: Eif3s10, Csma, Eif3, A830012B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13669
VEGA: 19
HGNC: HGNC:3271
Homologene: 2779
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, mitosin, Lek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Bora
Name: bora, aurora kinase A activator
Synonyms: 6720463M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 77744
VEGA: 14
Homologene: 11728
Dhx8
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 8
Synonyms: RNA helicase, mDEAH6, Ddx8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217207
HGNC: HGNC:2749
Homologene: 3628
Rnf14
Name: ring finger protein 14
Synonyms: D18Ertd188e, 2610005D23Rik, Triad2, 2310075C09Rik, D7Bwg0165e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 56736
VEGA: 18
Homologene: 129170
Mphosph8
Name: M-phase phosphoprotein 8
Synonyms: 1500035L22Rik, 4930548G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75339
Homologene: 11380
Lpl
Name: lipoprotein lipase
Synonyms: O 1-4-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16956
HGNC: HGNC:6677
Homologene: 200
Hnrnpdl
Name: heterogeneous nuclear ribonucleoprotein D-like
Synonyms: Hnrpdl, D5Ertd650e, JKTBP, D5Wsu145e, hnRNP-DL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50926
HGNC: HGNC:5037
Homologene: 75314
Dedd2
Name: death effector domain-containing DNA binding protein 2
Synonyms: FLAME-3, 2410050E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67379
Homologene: 23569
Nudt4
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 4
Synonyms: DIPP2beta, 4933436C10Rik, DIPP2alpha, DIPP2, HDCMB47P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71207
VEGA: 10
HGNC: HGNC:8051
Homologene: 41726
Dennd5b
Name: DENN/MADD domain containing 5B
Synonyms: D030011O10Rik, 9330160C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320560
Homologene: 44911
Clec4b2
Name: C-type lectin domain family 4, member b2
Synonyms: F830043G12Rik, mDCAR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 381809
Homologene: 128249
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: D7Ertd565e, Nalp-theta, Nalp9a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233001
Homologene: 116072
Rabl6
Name: RAB, member RAS oncogene family-like 6
Synonyms: Rbel1b, Rbel1, Rbel1a, B230208H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227624
Homologene: 11674
1700022I11Rik
Name: RIKEN cDNA 1700022I11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67317
Homologene: 52406
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Adamts9
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
Synonyms: UND3, Mhdaund3, 8430403M15Rik, 1810011L16Rik, Mhdaund4, Gsfund3, E030027K14Rik, UND4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101401
Homologene: 18821
Myt1l
Name: myelin transcription factor 1-like
Synonyms: Png-1, C630034G21Rik, Nztf1, Pmng1, 2900046C06Rik, 2900093J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17933
VEGA: 12
HGNC: HGNC:7623
Homologene: 7435
Mroh1
Name: maestro heat-like repeat family member 1
Synonyms: Heatr7a, D330001F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223658
Homologene: 44882
Vmn2r73
Name: vomeronasal 2, receptor 73
Synonyms: EG620928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620928
Homologene: 115466
Adamts19
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240322
VEGA: 18
Homologene: 15860
Ephb1
Name: Eph receptor B1
Synonyms: C130099E04Rik, Hek6, Elkh, Cek6, Net, Elk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270190
HGNC: HGNC:3392
Homologene: 20936
Gbp7
Name: guanylate binding protein 7
Synonyms: 9830147J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229900
Homologene: 138296
Spag17
Name: sperm associated antigen 17
Synonyms: PF6, 4931427F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74362
Homologene: 52601
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: Oatp1b2, 7330442B20Rik, Slc21a10, Slc21a6, mlst-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28253
Homologene: 75119
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319807
Homologene: 14974
Idi1
Name: isopentenyl-diphosphate delta isomerase
Synonyms: 4832416K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319554
HGNC: HGNC:5387
Homologene: 3315
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320492
Homologene: 14194
Olfr1045
Name: olfactory receptor 1045
Synonyms: MOR185-2, GA_x6K02T2Q125-47672825-47671878
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259019
Homologene: 128246
Hook3
Name: hook microtubule tethering protein 3
Synonyms: 5830454D03Rik, E330005F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320191
Homologene: 13022
Olfr46
Name: olfactory receptor 46
Synonyms: MOR253-8, IF5, GA_x6K02T2PBJ9-42759973-42760905, ID12, IB7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18345
Homologene: 110491
Scnm1
Name: sodium channel modifier 1
Synonyms: 3110001I17Rik, Scnm1-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69269
Homologene: 11431
Hoxb4
Name: homeobox B4
Synonyms: Hox-2.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15412
HGNC: HGNC:5115
Homologene: 32095
Olfr918
Name: olfactory receptor 918
Synonyms: MOR164-3, GA_x6K02T2PVTD-32375756-32374818
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258372
VEGA: 9
Olfr281
Name: olfactory receptor 281
Synonyms: MOR160-5, GA_x6K02T2NBG7-5275017-5274082
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 258277
Homologene: 133703
Tnnt2
Name: troponin T2, cardiac
Synonyms: cardiac TnT, Tnt, cTnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21956
Homologene: 68050
Tymp
Name: thymidine phosphorylase
Synonyms: Ecgf1, PD-ECGF, Pdgfec, 2900072D10Rik, gliostatin, PDECGF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 72962
VEGA: 15
HGNC: HGNC:3148
Homologene: 1474
Zc2hc1b
Name: zinc finger, C2HC-type containing 1B
Synonyms: Fam164b, 4930519B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75122
VEGA: 10
Homologene: 77965
Bin2
Name: bridging integrator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 668218
HGNC: HGNC:1053
Homologene: 22965
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 11,798,528 bp
  • G to T, chromosome 1 at 87,226,234 bp
  • A to G, chromosome 1 at 135,849,434 bp
  • T to C, chromosome 1 at 189,658,104 bp
  • C to T, chromosome 2 at 25,583,825 bp
  • A to C, chromosome 2 at 86,198,317 bp
  • T to C, chromosome 3 at 95,130,285 bp
  • A to T, chromosome 3 at 100,124,185 bp
  • G to A, chromosome 3 at 142,545,936 bp
  • A to G, chromosome 4 at 42,972,511 bp
  • T to C, chromosome 5 at 63,805,031 bp
  • C to T, chromosome 5 at 100,036,481 bp
  • T to C, chromosome 5 at 121,154,526 bp
  • T to C, chromosome 6 at 92,889,949 bp
  • A to T, chromosome 6 at 123,204,141 bp
  • A to C, chromosome 6 at 141,663,670 bp
  • A to G, chromosome 6 at 149,068,695 bp
  • G to A, chromosome 7 at 25,211,290 bp
  • T to A, chromosome 7 at 26,567,977 bp
  • T to C, chromosome 7 at 27,335,680 bp
  • T to A, chromosome 7 at 85,858,221 bp
  • A to G, chromosome 7 at 140,610,681 bp
  • C to A, chromosome 8 at 26,110,785 bp
  • A to T, chromosome 8 at 68,896,649 bp
  • C to A, chromosome 9 at 38,672,570 bp
  • T to C, chromosome 9 at 101,971,104 bp
  • C to A, chromosome 10 at 13,171,311 bp
  • A to G, chromosome 10 at 95,551,456 bp
  • A to G, chromosome 11 at 58,999,567 bp
  • T to C, chromosome 11 at 96,318,533 bp
  • C to T, chromosome 11 at 101,764,313 bp
  • G to A, chromosome 12 at 29,832,332 bp
  • T to C, chromosome 12 at 29,842,519 bp
  • T to A, chromosome 13 at 8,890,470 bp
  • A to G, chromosome 14 at 56,668,541 bp
  • A to T, chromosome 14 at 99,062,294 bp
  • A to T, chromosome 15 at 73,276,865 bp
  • A to G, chromosome 15 at 76,430,223 bp
  • GC to GCC, chromosome 15 at 89,374,364 bp
  • C to T, chromosome 15 at 98,456,766 bp
  • A to G, chromosome 15 at 100,645,148 bp
  • A to G, chromosome 17 at 71,349,719 bp
  • T to C, chromosome 18 at 38,301,670 bp
  • G to A, chromosome 18 at 58,968,774 bp
  • C to T, chromosome 19 at 36,983,542 bp
  • T to C, chromosome 19 at 60,772,130 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6082 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044241-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.