Strain Name:
C57BL/6J-MtgxR6088Btlr
Stock Number:
044245-MU
Citation ID:
RRID:MMRRC_044245-MU
Other Names:
R6088 (G1)
Major Collection:

Gene Information

Ptprf
Name: protein tyrosine phosphatase, receptor type, F
Synonyms: LAR, RPTP-LAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Elf1
Name: E74-like factor 1
Synonyms: Elf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13709
VEGA: 14
HGNC: HGNC:3316
Homologene: 7303
Mad1l1
Name: MAD1 mitotic arrest deficient 1-like 1
Synonyms: Mad1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17120
HGNC: HGNC:6762
Homologene: 74500
Pafah2
Name: platelet-activating factor acetylhydrolase 2
Synonyms: 2310074E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100163
HGNC: HGNC:8579
Homologene: 37309
Rbpj
Name: recombination signal binding protein for immunoglobulin kappa J region
Synonyms: RBP-J kappa, Igkrsbp, Igkjrb, CBF1, Rbpsuh, RBPjk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19664
HGNC: HGNC:5724
Homologene: 7511
Pibf1
Name: progesterone immunomodulatory binding factor 1
Synonyms: 1700017E21Rik, 4930513H15Rik, D14Ertd581e, 4933439E17Rik, 4933438D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 52023
VEGA: 14
Homologene: 4628
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: Gtar, 4933425K22Rik, A130069E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81702
Homologene: 82403
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: C030005G16Rik, Walp3, Tip5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: F830021D11Rik, 1110020K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224648
Homologene: 9816
Arid4a
Name: AT rich interactive domain 4A (RBP1-like)
Synonyms: A630067N03Rik, Rbbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238247
HGNC: HGNC:9885
Homologene: 11303
Fam129b
Name: family with sequence similarity 129, member B
Synonyms: 9130404D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227737
Homologene: 11269
Samd7
Name: sterile alpha motif domain containing 7
Synonyms: 4930597A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75953
Homologene: 18802
Card6
Name: caspase recruitment domain family, member 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239319
Homologene: 13067
Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Synonyms: Ftz-F1, SF-1, ELP, steroidogenic factor 1, adrenal 4-binding protein, Ad4BP, SF1, Ftzf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26423
HGNC: HGNC:7983
Homologene: 3638
St6galnac3
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Synonyms: Siat7c, ST6GalNAc III
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20447
Homologene: 7938
Rcc1
Name: regulator of chromosome condensation 1
Synonyms: 4931417M11Rik, Chc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100088
HGNC: HGNC:1913
Homologene: 55567
Zfp740
Name: zinc finger protein 740
Synonyms: 1110034O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68744
Homologene: 129530
Def8
Name: differentially expressed in FDCP 8
Synonyms: D8Ertd713e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23854
Homologene: 14279
Zfp574
Name: zinc finger protein 574
Synonyms: A630056B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232976
Homologene: 11238
Ska3
Name: spindle and kinetochore associated complex subunit 3
Synonyms: F630043A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219114
VEGA: 14
Homologene: 124284
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54403
Homologene: 55776
Ciita
Name: class II transactivator
Synonyms: Gm9475, C2ta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12265
VEGA: 16
HGNC: HGNC:7067
Homologene: 207
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83379
Homologene: 12820
Kcp
Name: kielin/chordin-like protein
Synonyms: KCP, LOC333088, Crim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 333088
Homologene: 87817
Fam184b
Name: family with sequence similarity 184, member B
Synonyms: 9630031F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 58227
Homologene: 137353
Mlxipl
Name: MLX interacting protein-like
Synonyms: bHLHd14, Wbscr14, WS-bHLH, ChREBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 58805
Homologene: 32507
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: FOAP-10, basilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, melastatin, LTRPC1, 4732499L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Gucy1b1
Name: guanylate cyclase 1, soluble, beta 1
Synonyms: Gucy1b3, beta 1 sGC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54195
HGNC: HGNC:4687
Homologene: 664
Zscan18
Name: zinc finger and SCAN domain containing 18
Synonyms: EG232875
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232875
Homologene: 122136
Oscar
Name: osteoclast associated receptor
Synonyms: mOSCAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232790
Homologene: 77042
Rhbdf1
Name: rhomboid 5 homolog 1
Synonyms: Dist, Egfr-rs, Dist1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13650
Homologene: 32085
Trpm8
Name: transient receptor potential cation channel, subfamily M, member 8
Synonyms: Trp-p8, TRPP8, CMR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171382
Homologene: 23433
Adamts19
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Myo5b
Name: myosin VB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Crybg2
Name: crystallin beta-gamma domain containing 2
Synonyms: Aim1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230806
Homologene: 19232
Tns4
Name: tensin 4
Synonyms: 9930017A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217169
Homologene: 13147
Cox7a2l
Name: cytochrome c oxidase subunit 7A2 like
Synonyms: EB1, SIG-81, COX7RP, COX7AR, SIG81
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20463
VEGA: 17
HGNC: HGNC:2289
Homologene: 3463
Zfp521
Name: zinc finger protein 521
Synonyms: Evi3, B930086A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225207
VEGA: 18
Homologene: 9151
Cts8
Name: cathepsin 8
Synonyms: CTS2, Epcs68, Epcs70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56094
VEGA: 13
Homologene: 129897
Ppip5k1
Name: diphosphoinositol pentakisphosphate kinase 1
Synonyms: Hisppd2a, B430315C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 327655
Homologene: 49395
Tgs1
Name: trimethylguanosine synthase 1
Synonyms: Ncoa6ip, Pimt, D4Ertd800e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 116940
Homologene: 32608
Oxa1l
Name: oxidase assembly 1-like
Synonyms: 1810020M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 69089
HGNC: HGNC:8526
Homologene: 31281
Gabrg3
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
Synonyms: B230362M20Rik, Gabrg-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14407
HGNC: HGNC:4088
Homologene: 22444
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: TSC403, Cd208, 1200002D17Rik, DC-LAMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239739
VEGA: 16
Homologene: 8670
Cd1d1
Name: CD1d1 antigen
Synonyms: Cd1d, Cd1a, CD1.1, Ly-38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12479
HGNC: HGNC:1637
Homologene: 1337
V1ra8
Name: vomeronasal 1 receptor, A8
Synonyms: Vmn1r-ps33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113850
Ndufb8
Name: NADH:ubiquinone oxidoreductase subunit B8
Synonyms: 2900010I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67264
HGNC: HGNC:7703
Homologene: 3668
Olfr988
Name: olfactory receptor 988
Synonyms: MOR203-5P, GA_x6K02T2Q125-46830591-46829662
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258166
Homologene: 103791
Slc26a1
Name: solute carrier family 26 (sulfate transporter), member 1
Synonyms: Sat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231583
Homologene: 32539
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Pla2g4d
Name: phospholipase A2, group IVD
Synonyms: 2610311B01Rik, Pla2delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78390
Homologene: 52252
Dld
Name: dihydrolipoamide dehydrogenase
Synonyms: branched chain alpha-keto acid dehydrogenase complex subunit E3, dihydrolipoyl dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13382
VEGA: 12
HGNC: HGNC:2898
Homologene: 84
Slc1a7
Name: solute carrier family 1 (glutamate transporter), member 7
Synonyms: EAAT5, A930031E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242607
Homologene: 21327
Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms: Clg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101497
Homologene: 16341
Pycr2
Name: pyrroline-5-carboxylate reductase family, member 2
Synonyms: 1810018M05Rik, P5cr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69051
Homologene: 8343
Esp24
Name: exocrine gland secreted peptide 24
Synonyms: Gm21947
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100126776
VEGA: 17
Olfr396-ps1
Name: olfactory receptor 396, pseudogene 1
Synonyms: GA_x6K02T2P1NL-4083149-4084087, MOR135-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258208
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 88,306,678 bp
  • G to A, chromosome 1 at 180,906,236 bp
  • T to C, chromosome 2 at 32,923,123 bp
  • T to C, chromosome 2 at 38,701,995 bp
  • T to C, chromosome 2 at 52,209,342 bp
  • T to A, chromosome 2 at 85,353,354 bp
  • C to T, chromosome 2 at 120,270,006 bp
  • C to A, chromosome 2 at 121,337,463 bp
  • G to A, chromosome 3 at 30,756,483 bp
  • T to C, chromosome 3 at 82,034,880 bp
  • G to T, chromosome 3 at 86,998,702 bp
  • C to T, chromosome 3 at 153,206,715 bp
  • T to A, chromosome 4 at 3,595,383 bp
  • G to A, chromosome 4 at 108,012,444 bp
  • G to A, chromosome 4 at 118,210,755 bp
  • G to T, chromosome 4 at 132,332,842 bp
  • A to T, chromosome 4 at 134,075,790 bp
  • A to G, chromosome 4 at 134,413,381 bp
  • C to A, chromosome 5 at 45,584,012 bp
  • C to T, chromosome 5 at 53,651,368 bp
  • C to T, chromosome 5 at 65,349,013 bp
  • T to A, chromosome 5 at 89,197,704 bp
  • C to T, chromosome 5 at 90,253,688 bp
  • C to T, chromosome 5 at 108,674,006 bp
  • T to C, chromosome 5 at 135,134,030 bp
  • T to A, chromosome 5 at 140,193,963 bp
  • A to T, chromosome 6 at 29,502,632 bp
  • T to C, chromosome 6 at 90,203,100 bp
  • G to A, chromosome 7 at 3,611,312 bp
  • A to T, chromosome 7 at 12,775,198 bp
  • T to A, chromosome 7 at 25,080,339 bp
  • C to T, chromosome 7 at 28,361,013 bp
  • T to A, chromosome 7 at 56,985,078 bp
  • A to T, chromosome 7 at 64,267,976 bp
  • G to T, chromosome 8 at 123,460,048 bp
  • TCTCCTC to TCTC, chromosome 10 at 128,114,642 bp
  • A to G, chromosome 11 at 32,212,007 bp
  • A to T, chromosome 11 at 73,928,823 bp
  • A to G, chromosome 11 at 99,073,720 bp
  • A to G, chromosome 12 at 31,340,989 bp
  • A to G, chromosome 12 at 71,022,236 bp
  • T to C, chromosome 13 at 61,253,966 bp
  • T to A, chromosome 14 at 54,367,694 bp
  • A to T, chromosome 14 at 57,816,694 bp
  • C to T, chromosome 14 at 79,567,261 bp
  • T to A, chromosome 14 at 99,179,358 bp
  • A to T, chromosome 15 at 5,105,019 bp
  • T to A, chromosome 15 at 102,208,808 bp
  • A to T, chromosome 16 at 5,104,988 bp
  • G to A, chromosome 16 at 10,511,931 bp
  • A to T, chromosome 16 at 19,673,398 bp
  • G to A, chromosome 17 at 27,884,605 bp
  • A to G, chromosome 17 at 39,040,010 bp
  • T to C, chromosome 17 at 71,255,124 bp
  • G to T, chromosome 17 at 83,503,972 bp
  • A to C, chromosome 18 at 13,846,109 bp
  • G to T, chromosome 18 at 58,902,102 bp
  • T to A, chromosome 18 at 74,720,898 bp
  • A to G, chromosome 19 at 44,555,025 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6088 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044245-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.