Strain Name:
C57BL/6J-MtgxR6103Btlr
Stock Number:
044253-MU
Citation ID:
RRID:MMRRC_044253-MU
Other Names:
R6103 (G1)
Major Collection:

Gene Information

Fgb
Name: fibrinogen beta chain
Synonyms: 2510049G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 110135
HGNC: HGNC:3662
Homologene: 3772
Notch2
Name: notch 2
Synonyms: Motch B, N2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18129
HGNC: HGNC:7882
Homologene: 7865
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, 6030440P17Rik, my, ne, b2b1562Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242022
Homologene: 18454
Avpr1b
Name: arginine vasopressin receptor 1B
Synonyms: V3/V1b pituitary vasopressin receptor, V3/V1b, V1bR, AVPR3, V1BR, VPR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26361
HGNC: HGNC:896
Homologene: 22678
Aco2
Name: aconitase 2, mitochondrial
Synonyms: Aco-2, Aco3, D10Wsu183e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11429
HGNC: HGNC:118
Homologene: 856
Abcc8
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Cep350
Name: centrosomal protein 350
Synonyms: 6430546F08Rik, 4933409L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74081
Homologene: 8879
Ccdc34
Name: coiled-coil domain containing 34
Synonyms: 4930522P10Rik, 2810027O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68201
Homologene: 12245
Cacna2d3
Name: calcium channel, voltage-dependent, alpha2/delta subunit 3
Synonyms: alpha 2 delta-3, alpha2delta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12294
Homologene: 74929
Glmp
Name: glycosylated lysosomal membrane protein
Synonyms: NCU-G1, 0610031J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56700
Homologene: 10562
Cyp4x1
Name: cytochrome P450, family 4, subfamily x, polypeptide 1
Synonyms: Cyp4a28-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 81906
Homologene: 75853
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: LOC381628, PGR23, Gpr113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381628
Homologene: 17826
Casp2
Name: caspase 2
Synonyms: Ich-1, Caspase-2, Nedd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12366
HGNC: HGNC:1503
Homologene: 7254
Rbm4
Name: RNA binding motif protein 4
Synonyms: Lark1, Rbm4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19653
HGNC: HGNC:9901
Homologene: 82510
Fut8
Name: fucosyltransferase 8
Synonyms: alpha (1,6) fucosyltransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 53618
VEGA: 12
HGNC: HGNC:4019
Homologene: 9650
Rsrc1
Name: arginine/serine-rich coiled-coil 1
Synonyms: SRrp53, 1200013F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66880
Homologene: 41147
Tmem183a
Name: transmembrane protein 183A
Synonyms: 1300007B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 57439
Homologene: 10757
Osbpl10
Name: oxysterol binding protein-like 10
Synonyms: 4933433D06Rik, OPR-10, C820004B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74486
Homologene: 69240
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: C6orf170, Bromi, D630037F22Rik, b2b2284Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 544696
VEGA: 10
Homologene: 51889
Cd209d
Name: CD209d antigen
Synonyms: SIGNR3, mSIGNR3, SIGN-R3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170779
HGNC: HGNC:1641
Homologene: 8603
Enam
Name: enamelin
Synonyms: abte
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13801
HGNC: HGNC:3344
Homologene: 9698
Ank1
Name: ankyrin 1, erythroid
Synonyms: Ank-1, pale
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11733
HGNC: HGNC:492
Homologene: 55427
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668940
Homologene: 66117
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: D28, PTPROt, PTP-phi, PTP-BK, PTP-U2, GLEPP1, PTP-oc, Ptpn15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Kif9
Name: kinesin family member 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16578
Homologene: 65620
Ankrd50
Name: ankyrin repeat domain 50
Synonyms: E430012K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99696
Homologene: 129859
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235505
Homologene: 25183
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Vmn2r88
Name: vomeronasal 2, receptor 88
Synonyms: V2r13, V2r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 669149
Homologene: 129606
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94229
Homologene: 23340
Fam110c
Name: family with sequence similarity 110, member C
Synonyms: 9030611O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104943
VEGA: 12
Homologene: 75262
Ift140
Name: intraflagellar transport 140
Synonyms: Wdtc2, Tce5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106633
Homologene: 40979
Naaladl1
Name: N-acetylated alpha-linked acidic dipeptidase-like 1
Synonyms: LOC381204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381204
Homologene: 21124
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384534
Homologene: 129605
Gpnmb
Name: glycoprotein (transmembrane) nmb
Synonyms: Dchil, Osteoactivin, DC-HIL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 93695
HGNC: HGNC:4462
Homologene: 1880
Adprhl1
Name: ADP-ribosylhydrolase like 1
Synonyms: Arh2, D330008N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234072
Homologene: 16311
Try10
Name: trypsin 10
Synonyms: trypsinogen 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 436522
HGNC: HGNC:9475
Homologene: 134623
Plcd1
Name: phospholipase C, delta 1
Synonyms: PLC-delta 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18799
VEGA: 9
HGNC: HGNC:9060
Homologene: 21252
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239546
VEGA: 15
Homologene: 27805
Setdb2
Name: SET domain, bifurcated 2
Synonyms: LOC239122, KMT1F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239122
Homologene: 12903
Olfr1019
Name: olfactory receptor 1019
Synonyms: GA_x6K02T2Q125-47320309-47319377, MOR180-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259017
Homologene: 17464
Fbxo6
Name: F-box protein 6
Synonyms: Fbx6b, FBG2, Fbs2, Fbxo6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50762
Homologene: 9274
Yipf7
Name: Yip1 domain family, member 7
Synonyms: Yip1b, 2310016N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75581
Homologene: 69367
Ms4a3
Name: membrane-spanning 4-domains, subfamily A, member 3
Synonyms: haematopoietic cell-specific transmembrane-4, HTm4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 170813
HGNC: HGNC:7317
Homologene: 4472
Mmd2
Name: monocyte to macrophage differentiation-associated 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75104
Homologene: 18425
Slc25a18
Name: solute carrier family 25 (mitochondrial carrier), member 18
Synonyms: 1500015I14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71803
Homologene: 57151
Obp2a
Name: odorant binding protein 2A
Synonyms: Lcn13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227627
Homologene: 136130
Mtres1
Name: mitochondrial transcription rescue factor 1
Synonyms: 1700021F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67851
Homologene: 41137
Gnpnat1
Name: glucosamine-phosphate N-acetyltransferase 1
Synonyms: EMeg32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54342
VEGA: 14
Homologene: 41323
Grxcr1
Name: glutaredoxin, cysteine rich 1
Synonyms: tde, pi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433899
Homologene: 42423
Zg16
Name: zymogen granule protein 16
Synonyms: 1810010M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69036
Homologene: 12296
Gm35315
Name: predicted gene, 35315
Synonyms: Gm20090
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 102638847
Homologene: 141161
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 131,609,417 bp
  • C to A, chromosome 1 at 134,348,146 bp
  • T to A, chromosome 1 at 155,924,576 bp
  • G to A, chromosome 2 at 25,700,151 bp
  • A to G, chromosome 2 at 62,234,465 bp
  • T to A, chromosome 2 at 76,918,255 bp
  • A to G, chromosome 2 at 85,841,432 bp
  • A to G, chromosome 2 at 110,018,007 bp
  • A to G, chromosome 2 at 155,618,743 bp
  • T to C, chromosome 3 at 38,454,429 bp
  • T to A, chromosome 3 at 53,549,788 bp
  • C to T, chromosome 3 at 66,994,649 bp
  • T to C, chromosome 3 at 83,043,863 bp
  • T to C, chromosome 3 at 88,328,031 bp
  • T to A, chromosome 3 at 98,135,743 bp
  • A to G, chromosome 4 at 115,111,667 bp
  • A to T, chromosome 4 at 148,149,522 bp
  • T to C, chromosome 5 at 30,196,267 bp
  • T to C, chromosome 5 at 68,166,204 bp
  • A to T, chromosome 5 at 69,541,062 bp
  • T to A, chromosome 5 at 88,502,328 bp
  • T to A, chromosome 5 at 110,078,271 bp
  • T to A, chromosome 5 at 114,245,881 bp
  • A to G, chromosome 5 at 142,567,863 bp
  • C to A, chromosome 6 at 41,356,550 bp
  • A to T, chromosome 6 at 42,279,880 bp
  • A to G, chromosome 6 at 49,042,886 bp
  • C to A, chromosome 6 at 120,789,438 bp
  • A to G, chromosome 6 at 137,400,706 bp
  • G to A, chromosome 7 at 10,171,400 bp
  • A to G, chromosome 7 at 46,119,021 bp
  • A to G, chromosome 7 at 127,050,576 bp
  • T to C, chromosome 8 at 3,878,304 bp
  • T to C, chromosome 8 at 13,222,055 bp
  • T to A, chromosome 8 at 23,113,983 bp
  • A to G, chromosome 9 at 78,698,314 bp
  • T to C, chromosome 9 at 110,489,849 bp
  • T to A, chromosome 9 at 115,061,872 bp
  • A to T, chromosome 9 at 119,072,041 bp
  • A to T, chromosome 10 at 43,532,920 bp
  • A to T, chromosome 10 at 56,150,883 bp
  • A to T, chromosome 11 at 76,799,799 bp
  • G to A, chromosome 12 at 31,074,795 bp
  • A to T, chromosome 12 at 77,331,947 bp
  • T to C, chromosome 14 at 29,396,489 bp
  • A to G, chromosome 14 at 45,383,399 bp
  • A to G, chromosome 14 at 51,415,369 bp
  • A to T, chromosome 14 at 55,505,427 bp
  • T to C, chromosome 14 at 59,409,532 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • T to C, chromosome 15 at 81,913,251 bp
  • A to G, chromosome 16 at 96,825,581 bp
  • T to A, chromosome 17 at 25,093,126 bp
  • C to T, chromosome 19 at 4,787,919 bp
  • G to A, chromosome 19 at 6,108,713 bp
  • A to T, chromosome 19 at 11,639,218 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6103 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044253-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.