Strain Name:
C57BL/6J-MtgxR6107Btlr
Stock Number:
044257-MU
Citation ID:
RRID:MMRRC_044257-MU
Other Names:
R6107 (G1)
Major Collection:

Gene Information

Bahcc1
Name: BAH domain and coiled-coil containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268515
Homologene: 129585
Ghitm
Name: growth hormone inducible transmembrane protein
Synonyms: 1010001P14Rik, C77840, Tmbim5, PTD010
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66092
VEGA: 14
Homologene: 8667
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: 5430402I23Rik, lectomedin 3, Lphn3, LEC3, D130075K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319387
Homologene: 22878
Kifap3
Name: kinesin-associated protein 3
Synonyms: KAP3, Smg GDS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16579
Homologene: 7799
Hells
Name: helicase, lymphoid specific
Synonyms: proliferation-associated SNF2-like, YFK8, LSH, PASG, E130115I21Rik, Lysh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 15201
HGNC: HGNC:4861
Homologene: 50037
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98999
Homologene: 10877
Erbin
Name: Erbb2 interacting protein
Synonyms: Erbb2ip, Erbin, 1700028E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 59079
Homologene: 41282
Tnpo2
Name: transportin 2 (importin 3, karyopherin beta 2b)
Synonyms: 1110034O24Rik, Kpnb2b, TRN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212999
Homologene: 8381
Miga1
Name: mitoguardin 1
Synonyms: Mita1, Fam73a, C030011O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 215708
Homologene: 18369
Exoc2
Name: exocyst complex component 2
Synonyms: 2410030I24Rik, Sec5, Sec5l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66482
Homologene: 10122
Smurf1
Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: 4930431E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75788
Homologene: 10712
E2f8
Name: E2F transcription factor 8
Synonyms: 4432406C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 108961
Homologene: 11654
Ufl1
Name: UFM1 specific ligase 1
Synonyms: Rcad, 1810074P20Rik, Maxer
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67490
Homologene: 9093
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19876
Homologene: 2206
Med23
Name: mediator complex subunit 23
Synonyms: X83317, 3000002A17Rik, ESTM7, Crsp3, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Inpp4a
Name: inositol polyphosphate-4-phosphatase, type I
Synonyms: 107kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269180
HGNC: HGNC:6074
Homologene: 2871
Atp2a3
Name: ATPase, Ca++ transporting, ubiquitous
Synonyms: Serca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53313
HGNC: HGNC:813
Homologene: 69131
Patl2
Name: protein associated with topoisomerase II homolog 2 (yeast)
Synonyms: Pat1a, 4930424G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67578
Homologene: 12155
Tas2r113
Name: taste receptor, type 2, member 113
Synonyms: T2R13, mt2r58, Tas2r13, mGR13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387345
Homologene: 130075
Flt1
Name: FMS-like tyrosine kinase 1
Synonyms: Flt-1, VEGFR-1, sFlt1, vascular endothelial growth factor receptor-1, VEGFR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14254
HGNC: HGNC:3763
Homologene: 134179
Ankrd52
Name: ankyrin repeat domain 52
Synonyms: G431002C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237615
Homologene: 18227
Slc8b1
Name: solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Synonyms: NCKX6, Slc24a6, NCLX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170756
Homologene: 41602
Pcdha1
Name: protocadherin alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 116731
HGNC: HGNC:8663
Homologene: 75093
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241919
Homologene: 76320
Slc25a48
Name: solute carrier family 25, member 48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328258
Homologene: 27065
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Ngrn
Name: neugrin, neurite outgrowth associated
Synonyms: neurite outgrowth associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83485
Homologene: 32330
Prl8a8
Name: prolactin family 8, subfamily a, member 81
Synonyms: Prlpc3, 1600032B14Rik, PLP-Cgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74188
Homologene: 137338
Slc25a34
Name: solute carrier family 25, member 34
Synonyms: LOC384071
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 384071
Homologene: 68806
Spag6l
Name: sperm associated antigen 6-like
Synonyms: PF16, Spag6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 50525
Homologene: 8252
Plch1
Name: phospholipase C, eta 1
Synonyms: PLCeta1, Plcl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 269437
Homologene: 88833
Fbxw19
Name: F-box and WD-40 domain protein 19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235612
Homologene: 110776
Olfr1286
Name: olfactory receptor 1286
Synonyms: MOR248-21, GA_x6K02T2Q125-72472405-72471488
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277562
Homologene: 73992
Pcsk1
Name: proprotein convertase subtilisin/kexin type 1
Synonyms: Nec1, Nec-1, Phpp-1, PC3, prohormone convertase 1/3, SPC3, PC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18548
HGNC: HGNC:8743
Homologene: 379
Ttyh3
Name: tweety family member 3
Synonyms: 2900029G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78339
Homologene: 18431
Rnase10
Name: ribonuclease, RNase A family, 10 (non-active)
Synonyms: 4930474F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75019
VEGA: 14
Homologene: 19166
Acyp2
Name: acylphosphatase 2, muscle type
Synonyms: 2310004B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75572
HGNC: HGNC:180
Homologene: 41776
Gm5493
Name: predicted gene 5493
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Gm18856
Name: predicted gene, 18856
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100417835
VEGA: 13
Kbtbd6
Name: kelch repeat and BTB (POZ) domain containing 6
Synonyms: Gm5465
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 432879
Homologene: 45156
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 37,377,748 bp
  • A to T, chromosome 1 at 163,868,769 bp
  • T to C, chromosome 2 at 111,420,655 bp
  • A to T, chromosome 2 at 122,127,486 bp
  • A to T, chromosome 2 at 167,037,081 bp
  • A to G, chromosome 3 at 31,257,610 bp
  • C to T, chromosome 3 at 63,702,023 bp
  • A to T, chromosome 3 at 152,335,399 bp
  • A to G, chromosome 4 at 25,251,999 bp
  • C to T, chromosome 4 at 141,623,495 bp
  • A to G, chromosome 5 at 81,688,563 bp
  • A to G, chromosome 5 at 120,529,600 bp
  • A to C, chromosome 5 at 140,633,562 bp
  • A to G, chromosome 5 at 144,894,504 bp
  • G to A, chromosome 5 at 147,603,593 bp
  • G to A, chromosome 6 at 132,893,014 bp
  • A to G, chromosome 7 at 48,867,676 bp
  • A to G, chromosome 7 at 80,261,877 bp
  • T to C, chromosome 8 at 85,053,475 bp
  • A to T, chromosome 9 at 105,892,272 bp
  • C to T, chromosome 9 at 109,495,766 bp
  • A to T, chromosome 10 at 24,906,034 bp
  • C to A, chromosome 10 at 128,387,012 bp
  • C to T, chromosome 11 at 30,506,354 bp
  • A to G, chromosome 11 at 72,988,461 bp
  • G to A, chromosome 11 at 120,272,888 bp
  • T to A, chromosome 13 at 13,965,734 bp
  • A to G, chromosome 13 at 27,511,464 bp
  • T to C, chromosome 13 at 30,876,797 bp
  • A to T, chromosome 13 at 56,465,078 bp
  • A to G, chromosome 13 at 75,127,848 bp
  • A to G, chromosome 13 at 103,833,892 bp
  • C to A, chromosome 14 at 37,125,209 bp
  • T to A, chromosome 14 at 51,009,294 bp
  • T to A, chromosome 14 at 79,453,113 bp
  • T to A, chromosome 16 at 16,781,788 bp
  • A to G, chromosome 16 at 72,983,829 bp
  • T to A, chromosome 17 at 22,748,096 bp
  • A to G, chromosome 18 at 36,932,301 bp
  • T to G, chromosome 19 at 38,953,649 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6107 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044257-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.