Strain Name:
C57BL/6J-MtgxR6112Btlr
Stock Number:
044261-MU
Citation ID:
RRID:MMRRC_044261-MU
Other Names:
R6112 (G1)
Major Collection:

Gene Information

Odc1
Name: ornithine decarboxylase, structural 1
Synonyms: ODC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18263
VEGA: 12
HGNC: HGNC:8109
Homologene: 1906
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Gpm6a
Name: glycoprotein m6a
Synonyms: Gpm6, M6A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234267
HGNC: HGNC:4460
Homologene: 3864
Magi1
Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Synonyms: BAP1, Gukmi1, WWP3, Baiap1, AIP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14924
HGNC: HGNC:946
Homologene: 31257
Pum1
Name: pumilio RNA-binding family member 1
Synonyms: Pumm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 80912
Homologene: 22830
Lcor
Name: ligand dependent nuclear receptor corepressor
Synonyms: 3110023F06Rik, Mlr2, A630025C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 212391
VEGA: 19
Homologene: 18153
Lmna
Name: lamin A
Synonyms: lamin A/C, Dhe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16905
HGNC: HGNC:6636
Homologene: 41321
Bag3
Name: BCL2-associated athanogene 3
Synonyms: Bcl-2-interacting death suppressor, Bis
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 29810
HGNC: HGNC:939
Homologene: 3162
Dapk3
Name: death-associated protein kinase 3
Synonyms: ZIP kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13144
VEGA: 10
HGNC: HGNC:2676
Homologene: 20353
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: Rnf164, 2900024N03Rik, Mnab, 9430019J22Rik, D930043C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 319817
Homologene: 28276
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98999
Homologene: 10877
Snx3
Name: sorting nexin 3
Synonyms: SDP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 54198
Homologene: 36144
Slx4ip
Name: SLX4 interacting protein
Synonyms: 2410004I22Rik, 2210009G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74243
Homologene: 49913
Erap1
Name: endoplasmic reticulum aminopeptidase 1
Synonyms: Arts1, PILSAP, ERAAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 80898
VEGA: 13
Homologene: 56754
Zfp600
Name: zinc finger protein 600
Synonyms: Gm13164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 667666
Homologene: 133076
Pamr1
Name: peptidase domain containing associated with muscle regeneration 1
Synonyms: E430002G05Rik, RAMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 210622
Homologene: 9134
Adh5
Name: alcohol dehydrogenase 5 (class III), chi polypeptide
Synonyms: Adh-5, Adh3, S-nitrosoglutathione reductase, GSNOR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11532
HGNC: HGNC:253
Homologene: 68076
Eef1g
Name: eukaryotic translation elongation factor 1 gamma
Synonyms: EF1G, 2610301D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67160
HGNC: HGNC:3213
Homologene: 20363
Pigt
Name: phosphatidylinositol glycan anchor biosynthesis, class T
Synonyms: CGI-06, NDAP, Ndap7, 4930534E15Rik, 2510012P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78928
Homologene: 6134
Ift172
Name: intraflagellar transport 172
Synonyms: avc1, wim, 4930553F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67661
Homologene: 15202
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: E130010M05Rik, [a]4(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Arhgap20
Name: Rho GTPase activating protein 20
Synonyms: 6530403F17Rik, A530023E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244867
Homologene: 18938
Zfp646
Name: zinc finger protein 646
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233905
Homologene: 8802
Ptprh
Name: protein tyrosine phosphatase, receptor type, H
Synonyms: SAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545902
HGNC: HGNC:9672
Homologene: 37693
Aplp1
Name: amyloid beta (A4) precursor-like protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11803
HGNC: HGNC:597
Homologene: 68447
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Gm10801
Name: predicted gene 10801
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, C030048J01Rik, Lba1, LOC235639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320429
Homologene: 45845
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241116
Homologene: 28093
Sppl2c
Name: signal peptide peptidase 2C
Synonyms: 4933407P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237958
Homologene: 18491
Pam
Name: peptidylglycine alpha-amidating monooxygenase
Synonyms: PHM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18484
HGNC: HGNC:8596
Homologene: 37369
Igsf3
Name: immunoglobulin superfamily, member 3
Synonyms: 2810035F16Rik, 4833439O17Rik, 1700016K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 78908
HGNC: HGNC:5950
Homologene: 1182
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: 1600012D06Rik, Abp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Usp4
Name: ubiquitin specific peptidase 4 (proto-oncogene)
Synonyms: F730026I20Rik, Unp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22258
Homologene: 20716
Noa1
Name: nitric oxide associated 1
Synonyms: 2610024G14Rik, mAtNOS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56412
Homologene: 10518
Rad51ap2
Name: RAD51 associated protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 209550
VEGA: 12
Homologene: 85245
Srms
Name: src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Synonyms: srm, A230069J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20811
Homologene: 7957
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74053
Homologene: 12938
Vmn2r60
Name: vomeronasal 2, receptor 60
Synonyms: Casr-rs3, EG637898, Gprc2a-rs3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 637898
Homologene: 129683
Abcc1
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Synonyms: Abcc1a, Mrp1, Mdrap, MRP, Abcc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241158
Homologene: 9561
Radil
Name: Ras association and DIL domains
Synonyms: D930005D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231858
Homologene: 77648
Cep250
Name: centrosomal protein 250
Synonyms: B230210E21Rik, Cep2, Inmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Olfr484
Name: olfactory receptor 484
Synonyms: GA_x6K02T2PBJ9-10454128-10453163, MOR204-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258492
Homologene: 36987
Tenm1
Name: teneurin transmembrane protein 1
Synonyms: Ten-m1, teneurin-1, TCAP-1, Odz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 23963
HGNC: HGNC:8117
Homologene: 56542
Hspa14
Name: heat shock protein 14
Synonyms: NST-1, Hsp70-4, HSP70L1, 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50497
Homologene: 74307
Prx
Name: periaxin
Synonyms: L-Periaxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 19153
Homologene: 76542
Cbarp
Name: calcium channel, voltage-dependent, beta subunit associated regulatory protein
Synonyms: Dos, R29144/1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 100503659
Homologene: 82309
Eef1akmt1
Name: EEF1A alpha lysine methyltransferase 1
Synonyms: Ayu21-96, Gt(Ayu21)96Imeg, 2510005D08Rik, N6amt2, GtAyu21-96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 68043
VEGA: 14
Homologene: 5952
Dctn5
Name: dynactin 5
Synonyms: p25 dynactin subunit, b2b315Clo, 4930427E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 59288
Homologene: 10998
Maf1
Name: MAF1 homolog, negative regulator of RNA polymerase III
Synonyms: Maf1, 1110068E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68877
Homologene: 49867
Trib1
Name: tribbles pseudokinase 1
Synonyms: A530090O15Rik, Trb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 211770
Homologene: 75216
Pcdhga2
Name: protocadherin gamma subfamily A, 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93710
HGNC: HGNC:8700
Homologene: 69262
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,903,139 bp
  • A to G, chromosome 1 at 82,453,883 bp
  • A to T, chromosome 1 at 92,870,962 bp
  • A to G, chromosome 1 at 97,834,468 bp
  • A to G, chromosome 1 at 150,618,936 bp
  • G to A, chromosome 2 at 3,498,068 bp
  • C to T, chromosome 2 at 37,378,887 bp
  • C to T, chromosome 2 at 41,341,882 bp
  • A to G, chromosome 2 at 98,664,064 bp
  • T to C, chromosome 2 at 102,611,608 bp
  • T to A, chromosome 2 at 137,046,744 bp
  • C to A, chromosome 2 at 155,994,583 bp
  • C to T, chromosome 2 at 164,506,445 bp
  • A to G, chromosome 2 at 167,038,206 bp
  • C to A, chromosome 2 at 181,207,987 bp
  • C to A, chromosome 3 at 88,486,621 bp
  • T to A, chromosome 3 at 101,451,006 bp
  • G to T, chromosome 3 at 138,451,268 bp
  • G to A, chromosome 4 at 130,730,280 bp
  • A to T, chromosome 4 at 146,195,131 bp
  • T to C, chromosome 5 at 31,256,897 bp
  • C to T, chromosome 5 at 77,309,746 bp
  • C to T, chromosome 5 at 142,543,644 bp
  • A to T, chromosome 6 at 48,908,691 bp
  • T to C, chromosome 6 at 93,745,590 bp
  • T to A, chromosome 7 at 4,597,923 bp
  • T to C, chromosome 7 at 27,516,548 bp
  • T to C, chromosome 7 at 30,435,477 bp
  • A to T, chromosome 7 at 42,195,423 bp
  • T to A, chromosome 7 at 108,125,162 bp
  • A to G, chromosome 7 at 122,133,237 bp
  • G to T, chromosome 7 at 127,879,018 bp
  • A to G, chromosome 7 at 128,541,832 bp
  • T to A, chromosome 7 at 141,863,305 bp
  • G to A, chromosome 8 at 55,054,810 bp
  • T to C, chromosome 9 at 51,829,384 bp
  • A to G, chromosome 9 at 108,356,504 bp
  • T to C, chromosome 9 at 111,391,737 bp
  • C to A, chromosome 10 at 42,526,046 bp
  • T to C, chromosome 10 at 80,135,371 bp
  • A to T, chromosome 10 at 81,184,030 bp
  • C to A, chromosome 10 at 119,993,232 bp
  • C to T, chromosome 11 at 94,409,246 bp
  • A to T, chromosome 11 at 104,187,137 bp
  • T to C, chromosome 12 at 11,457,289 bp
  • T to G, chromosome 12 at 17,549,472 bp
  • G to T, chromosome 13 at 74,646,279 bp
  • A to T, chromosome 14 at 57,549,873 bp
  • C to T, chromosome 15 at 59,651,638 bp
  • A to G, chromosome 15 at 76,352,112 bp
  • A to G, chromosome 16 at 14,460,916 bp
  • C to T, chromosome 16 at 32,775,783 bp
  • T to A, chromosome 18 at 37,669,559 bp
  • T to C, chromosome 19 at 8,977,591 bp
  • T to C, chromosome 19 at 41,559,081 bp
  • C to T, chromosome X at 42,827,195 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6112 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044261-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.