Strain Name:
C57BL/6J-MtgxR6142Btlr
Stock Number:
044289-MU
Citation ID:
RRID:MMRRC_044289-MU
Other Names:
R6142 (G1)
Major Collection:

Gene Information

Hyal1
Name: hyaluronoglucosaminidase 1
Synonyms: Hyal-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 15586
HGNC: HGNC:5320
Homologene: 5277
Sbf2
Name: SET binding factor 2
Synonyms: B430219L04Rik, SBF2, 4833411B01Rik, mMTMH1, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Gria2
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2)
Synonyms: Glur2, Glur-2, GluR2, GluA2, GluR-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14800
HGNC: HGNC:4572
Homologene: 20225
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66860
Homologene: 18946
Prrc2c
Name: proline-rich coiled-coil 2C
Synonyms: 9630039I18Rik, Bat2l2, Bat2d, 1810043M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226562
Homologene: 41015
Akap12
Name: A kinase (PRKA) anchor protein (gravin) 12
Synonyms: Srcs5, SSeCKS, Tsga12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Ranbp3
Name: RAN binding protein 3
Synonyms: 2610024N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71810
VEGA: 17
HGNC: HGNC:9850
Homologene: 136516
Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: Nrf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18024
HGNC: HGNC:7782
Homologene: 2412
Plcg2
Name: phospholipase C, gamma 2
Synonyms: PLCgamma2, Plcg-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234779
HGNC: HGNC:9066
Homologene: 55671
Lamb2
Name: laminin, beta 2
Synonyms: Lamb-2, npht, Lams
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: b2b1035Clo, 5730509K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231214
Homologene: 18159
Slc6a3
Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Synonyms: DAT, Dat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13162
VEGA: 13
Homologene: 55547
Arfgap3
Name: ADP-ribosylation factor GTPase activating protein 3
Synonyms: 9130416J18Rik, 1810035F16Rik, 1810004P07Rik, 0610009H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66251
VEGA: 15
HGNC: HGNC:661
Homologene: 134103
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: Sema6A-1, sema, A730020P05Rik, VIa, Semaq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20358
Homologene: 32426
Zfp148
Name: zinc finger protein 148
Synonyms: 2210405J08Rik, BFCOL1, ZBP-89, beta enolase repressor factor 1, BERF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 22661
VEGA: 16
Homologene: 8003
Lnpep
Name: leucyl/cystinyl aminopeptidase
Synonyms: 2010309L07Rik, 4732490P18Rik, IRAP, vp165, gp160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240028
VEGA: 17
HGNC: HGNC:6656
Homologene: 21148
Lrch1
Name: leucine-rich repeats and calponin homology (CH) domain containing 1
Synonyms: Chdc1, 4832412D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380916
VEGA: 14
Homologene: 32244
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328783
VEGA: 17
Homologene: 18633
Pgm5
Name: phosphoglucomutase 5
Synonyms: aciculin, 9530034F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226041
HGNC: HGNC:8908
Homologene: 74881
Tdrd6
Name: tudor domain containing 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 210510
Homologene: 19364
Slc13a4
Name: solute carrier family 13 (sodium/sulfate symporters), member 4
Synonyms: SUT1, 9630060C05Rik, SUT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243755
Homologene: 69125
Rpap2
Name: RNA polymerase II associated protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231571
Homologene: 11733
Tpsg1
Name: tryptase gamma 1
Synonyms: Prss31, TMT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 26945
Homologene: 74994
Alpk2
Name: alpha-kinase 2
Synonyms: Hak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225638
Homologene: 50475
Agtr1b
Name: angiotensin II receptor, type 1b
Synonyms: AT1B, Angtr-1b, Agtr-1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11608
HGNC: HGNC:336
Homologene: 84871
Kcnh7
Name: potassium voltage-gated channel, subfamily H (eag-related), member 7
Synonyms: 9330137I11Rik, Kv11.3, erg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 170738
Homologene: 13249
AW551984
Name: expressed sequence AW551984
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244810
Spg20
Name: spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
Synonyms: TAHCCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229285
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: 4930415K13Rik, Rgsl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240816
Homologene: 129962
Adcy6
Name: adenylate cyclase 6
Synonyms: AC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11512
VEGA: 15
HGNC: HGNC:237
Homologene: 22400
Tmem168
Name: transmembrane protein 168
Synonyms: 5730526F17Rik, 8430437G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101118
Homologene: 11202
Tas2r140
Name: taste receptor, type 2, member 140
Synonyms: mTRB3, Tas2r40, T2R40, mt2r64, TRB5, Tas2r13, TRB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387616
Homologene: 87013
Hmgxb3
Name: HMG box domain containing 3
Synonyms: 2510002C16Rik, A630042L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106894
VEGA: 18
Homologene: 44229
Tnk2
Name: tyrosine kinase, non-receptor, 2
Synonyms: activated p21cdc42Hs kinase, ACK1, P21cdc42Hs kinase, Pyk1, Ack
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 51789
Homologene: 4224
Bmp8b
Name: bone morphogenetic protein 8b
Synonyms: Op3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12164
HGNC: HGNC:1075
Homologene: 130625
Msl3l2
Name: MSL3 like 2
Synonyms: 1700060H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 73390
VEGA: 10
Homologene: 128448
Cnot6l
Name: CCR4-NOT transcription complex, subunit 6-like
Synonyms: 4932442K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231464
Homologene: 100830
Crocc2
Name: ciliary rootlet coiled-coil, rootletin family member 2
Synonyms: LOC381284, E030010N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381284
Homologene: 141152
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 627569
Homologene: 129606
Il5
Name: interleukin 5
Synonyms: Il-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16191
HGNC: HGNC:6016
Homologene: 679
Ganc
Name: glucosidase, alpha; neutral C
Synonyms: 5830445O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76051
HGNC: HGNC:4139
Homologene: 25627
Rxrg
Name: retinoid X receptor gamma
Synonyms: Nr2b3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20183
Homologene: 21373
Zfp773
Name: zinc finger protein 773
Synonyms: 2810409K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76373
Homologene: 137393
Col25a1
Name: collagen, type XXV, alpha 1
Synonyms: 2700062B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77018
Homologene: 57111
Zfp40
Name: zinc finger protein 40
Synonyms: Zfp-40, NTfin12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22700
Homologene: 136312
Tram1l1
Name: translocation associated membrane protein 1-like 1
Synonyms: A830091N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229801
Homologene: 17142
Hipk4
Name: homeodomain interacting protein kinase 4
Synonyms: LOC233020
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233020
Homologene: 16970
Gm8212
Name: predicted gene 8212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 666647
Homologene: 128452
Gm28168
Name: predicted gene 28168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 93,190,479 bp
  • C to A, chromosome 1 at 117,947,948 bp
  • A to G, chromosome 1 at 153,812,238 bp
  • T to C, chromosome 1 at 162,710,387 bp
  • G to T, chromosome 1 at 167,632,622 bp
  • A to T, chromosome 2 at 59,833,222 bp
  • T to C, chromosome 2 at 62,739,360 bp
  • T to C, chromosome 2 at 75,679,417 bp
  • T to C, chromosome 2 at 120,430,737 bp
  • T to C, chromosome 3 at 20,316,394 bp
  • T to G, chromosome 3 at 55,117,248 bp
  • T to C, chromosome 3 at 80,801,717 bp
  • T to C, chromosome 3 at 124,321,443 bp
  • T to A, chromosome 3 at 130,583,329 bp
  • A to T, chromosome 4 at 123,115,250 bp
  • G to T, chromosome 5 at 43,703,198 bp
  • C to T, chromosome 5 at 96,082,978 bp
  • T to C, chromosome 5 at 107,598,298 bp
  • T to A, chromosome 5 at 109,092,897 bp
  • C to A, chromosome 6 at 13,591,369 bp
  • G to A, chromosome 6 at 35,301,783 bp
  • C to T, chromosome 6 at 133,055,735 bp
  • T to C, chromosome 7 at 7,132,482 bp
  • G to A, chromosome 7 at 27,529,165 bp
  • A to G, chromosome 7 at 110,348,975 bp
  • C to A, chromosome 8 at 117,585,271 bp
  • G to T, chromosome 9 at 39,597,114 bp
  • G to A, chromosome 9 at 107,579,374 bp
  • A to T, chromosome 9 at 108,485,618 bp
  • C to A, chromosome 10 at 4,313,740 bp
  • A to G, chromosome 10 at 56,115,365 bp
  • G to A, chromosome 11 at 53,720,978 bp
  • A to T, chromosome 13 at 73,544,783 bp
  • T to C, chromosome 14 at 44,201,227 bp
  • T to C, chromosome 14 at 74,947,500 bp
  • T to C, chromosome 15 at 83,350,127 bp
  • T to C, chromosome 15 at 98,598,422 bp
  • T to A, chromosome 16 at 32,670,099 bp
  • T to C, chromosome 16 at 33,495,459 bp
  • A to G, chromosome 17 at 17,566,681 bp
  • C to A, chromosome 17 at 23,176,337 bp
  • A to T, chromosome 17 at 25,372,486 bp
  • T to C, chromosome 17 at 25,744,557 bp
  • A to G, chromosome 17 at 43,629,482 bp
  • T to C, chromosome 17 at 56,686,018 bp
  • T to C, chromosome 18 at 47,281,199 bp
  • T to C, chromosome 18 at 61,136,237 bp
  • T to C, chromosome 18 at 65,305,385 bp
  • A to C, chromosome 19 at 24,824,408 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6142 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044289-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.