Strain Name:
C57BL/6J-MtgxR6166Btlr
Stock Number:
044312-MU
Citation ID:
RRID:MMRRC_044312-MU
Other Names:
R6166 (G1)
Major Collection:

Gene Information

Plg
Name: plasminogen
Synonyms: Pg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18815
VEGA: 17
HGNC: HGNC:9071
Homologene: 55452
Arpp21
Name: cyclic AMP-regulated phosphoprotein, 21
Synonyms: R3hdm3, 0710001E13Rik, D9Bwg1012e, Tarpp, ARPP-21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74100
Homologene: 32306
Fancd2
Name: Fanconi anemia, complementation group D2
Synonyms: 2410150O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 211651
HGNC: HGNC:3585
Homologene: 13212
Lgals9
Name: lectin, galactose binding, soluble 9
Synonyms: Lgals5, galectin-9, gal-9, LGALS35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16859
Homologene: 134662
Fam117a
Name: family with sequence similarity 117, member A
Synonyms: 5730593F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215512
Homologene: 12775
Prdm2
Name: PR domain containing 2, with ZNF domain
Synonyms: 4833427P12Rik, LOC381568, E330024L24Rik, Riz, KMT8, Riz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110593
HGNC: HGNC:9347
Homologene: 40822
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319481
Homologene: 38685
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: D3Ertd775e, Lba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Srbd1
Name: S1 RNA binding domain 1
Synonyms: D530025C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78586
VEGA: 17
Homologene: 9994
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100683
Homologene: 39246
Ago2
Name: argonaute RISC catalytic subunit 2
Synonyms: 2310051F07Rik, Eif2c2, 1110029L17Rik, argonaute 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239528
HGNC: HGNC:3263
Homologene: 81825
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Sf3a3
Name: splicing factor 3a, subunit 3
Synonyms: 4930512K19Rik, 60kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75062
Homologene: 4949
Ndufs6
Name: NADH:ubiquinone oxidoreductase core subunit S6
Synonyms: IP13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 407785
HGNC: HGNC:7713
Homologene: 37935
Atg13
Name: autophagy related 13
Synonyms: 1110053A20Rik, D2Ertd391e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51897
Homologene: 32229
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Nodal
Name: nodal
Synonyms: Tg.413d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18119
HGNC: HGNC:7865
Homologene: 8417
Ap1ar
Name: adaptor-related protein complex 1 associated regulatory protein
Synonyms: Gadkin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 211556
Homologene: 10236
Arhgef17
Name: Rho guanine nucleotide exchange factor (GEF) 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 207212
Homologene: 129601
Olfm3
Name: olfactomedin 3
Synonyms: B230206G02Rik, optimedin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229759
Homologene: 17103
Src
Name: Rous sarcoma oncogene
Synonyms: pp60c-src
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20779
Homologene: 21120
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Slc38a9
Name: solute carrier family 38, member 9
Synonyms: 4833412L08Rik, 6720411P22Rik, 9130023D20Rik, 9430067K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268706
VEGA: 13
Homologene: 18139
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: E030006K04Rik, Centd3, DRAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106952
VEGA: 18
Homologene: 11199
Camta2
Name: calmodulin binding transcription activator 2
Synonyms: Kiaa0909-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216874
Homologene: 9021
Efcab6
Name: EF-hand calcium binding domain 6
Synonyms: 4931407K02Rik, 4932408N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 77627
Homologene: 11259
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Hug, Jbts17, b2b012Clo, 2410089E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73692
Homologene: 11315
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Rhobtb2
Name: Rho-related BTB domain containing 2
Synonyms: Dbc2, E130206H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 246710
VEGA: 14
Homologene: 22873
Vmn2r70
Name: vomeronasal 2, receptor 70
Synonyms: EG620835
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 670940
HGNC: null
Homologene: 115466
Tgm7
Name: transglutaminase 7
Synonyms: TGz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 640543
Homologene: 14192
Vmn2r56
Name: vomeronasal 2, receptor 56
Synonyms: EG629079
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 629079
HGNC: null
Homologene: 104040
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21826
VEGA: 17
Homologene: 2438
Gm16432
Name: predicted gene 16432
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Filip1
Name: filamin A interacting protein 1
Synonyms: FILIP, 5730485H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70598
Homologene: 6700
Tbc1d9b
Name: TBC1 domain family, member 9B
Synonyms: 2700008N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76795
Homologene: 28106
Psg21
Name: pregnancy-specific glycoprotein 21
Synonyms: 1600025N01Rik, 1600026N13Rik, 1600019C01Rik, cea8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72242
HGNC: null
Homologene: 110989
Csf2rb
Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Synonyms: Il3rb1, AIC2B, Bc, common beta chain, CDw131, Csf2rb1, Il3r, beta c, Il5rb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12983
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Ccdc40
Name: coiled-coil domain containing 40
Synonyms: B930008I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207607
Homologene: 27890
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: SRRP129, 2610510E10Rik, SIP1, 1110061H03Rik, CASP11, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 72193
VEGA: 15
Homologene: 37957
Gpx5
Name: glutathione peroxidase 5
Synonyms: Arep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14780
HGNC: HGNC:4557
Homologene: 1155
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216188
Homologene: 51942
Olfr730
Name: olfactory receptor 730
Synonyms: MOR247-1, GA_x6K02T2PMLR-5881670-5880717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258486
Homologene: 17269
Gm15446
Name: predicted gene 15446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100642166
HGNC: null
Homologene: null
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74053
Homologene: 12938
Dll4
Name: delta like canonical Notch ligand 4
Synonyms: Delta4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 54485
HGNC: HGNC:2910
Homologene: 10411
Tctn3
Name: tectonic family member 3
Synonyms: Tect3, 4930521E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67590
Homologene: 9221
Cnot6l
Name: CCR4-NOT transcription complex, subunit 6-like
Synonyms: 4932442K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231464
Homologene: 100830
Acot2
Name: acyl-CoA thioesterase 2
Synonyms: Mte1, MTE-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 171210
Homologene: 25661
Bmp8a
Name: bone morphogenetic protein 8a
Synonyms: OP2, osteogenic protein 2, Bmp7r1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12163
Homologene: 135983
Naprt
Name: nicotinate phosphoribosyltransferase
Synonyms: 9130210N20Rik, Naprt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223646
VEGA: 15
Homologene: 82285
Lypd10
Name: Ly6/PLAUR domain containing 10
Synonyms: BC049730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232972
HGNC: null
Homologene: null
Olfr420
Name: olfactory receptor 420
Synonyms: MOR105-10, GA_x6K02T2P20D-20995211-20994246
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258302
Homologene: 17185
Cnn2
Name: calponin 2
Synonyms: h2-calponin, Calpo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12798
HGNC: HGNC:2156
Homologene: 3215
Tm4sf19
Name: transmembrane 4 L six family member 19
Synonyms: EG277203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 277203
Homologene: 64632
Fgf20
Name: fibroblast growth factor 20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 80857
HGNC: HGNC:3677
Homologene: 10527
Olfr803
Name: olfactory receptor 803
Synonyms: MOR111-3, GA_x6K02T2PULF-11370664-11369738
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258547
Homologene: 105153
Sowahc
Name: sosondowah ankyrin repeat domain family member C
Synonyms: Ankrd57, C820004L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 268301
Homologene: 49723
Gm7363
Name: predicted gene 7363
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 664841
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 174,159,093 bp
  • A to G, chromosome 1 at 178,103,837 bp
  • G to A, chromosome 2 at 31,369,262 bp
  • G to T, chromosome 2 at 82,980,727 bp
  • G to T, chromosome 2 at 91,676,391 bp
  • A to G, chromosome 2 at 119,334,626 bp
  • A to G, chromosome 2 at 121,099,058 bp
  • A to G, chromosome 2 at 157,468,522 bp
  • G to A, chromosome 3 at 86,354,307 bp
  • T to A, chromosome 3 at 115,122,425 bp
  • A to G, chromosome 3 at 127,812,528 bp
  • T to C, chromosome 4 at 123,324,678 bp
  • T to C, chromosome 4 at 124,723,384 bp
  • A to C, chromosome 4 at 143,134,736 bp
  • T to C, chromosome 5 at 96,079,940 bp
  • T to A, chromosome 5 at 109,942,780 bp
  • T to A, chromosome 5 at 144,781,981 bp
  • T to A, chromosome 6 at 113,555,251 bp
  • A to T, chromosome 7 at 3,983,785 bp
  • A to G, chromosome 7 at 12,694,020 bp
  • A to T, chromosome 7 at 18,656,739 bp
  • A to T, chromosome 7 at 24,714,219 bp
  • A to G, chromosome 7 at 85,565,981 bp
  • GCG to GCGACGGCGACG, chromosome 7 at 97,579,907 bp
  • A to T, chromosome 7 at 100,876,492 bp
  • T to C, chromosome 8 at 40,279,840 bp
  • T to C, chromosome 8 at 44,952,485 bp
  • C to T, chromosome 8 at 111,472,661 bp
  • T to C, chromosome 9 at 79,819,454 bp
  • T to C, chromosome 9 at 112,119,198 bp
  • A to G, chromosome 10 at 59,222,360 bp
  • C to A, chromosome 10 at 61,424,558 bp
  • A to G, chromosome 10 at 79,988,727 bp
  • C to T, chromosome 10 at 83,493,424 bp
  • A to T, chromosome 10 at 120,072,718 bp
  • A to T, chromosome 10 at 129,691,279 bp
  • A to G, chromosome 11 at 50,135,846 bp
  • G to C, chromosome 11 at 70,674,261 bp
  • C to T, chromosome 11 at 78,971,358 bp
  • T to C, chromosome 11 at 95,380,781 bp
  • T to C, chromosome 11 at 119,232,001 bp
  • A to T, chromosome 12 at 83,992,604 bp
  • A to T, chromosome 13 at 21,289,265 bp
  • G to A, chromosome 13 at 73,317,941 bp
  • T to G, chromosome 13 at 112,695,267 bp
  • C to T, chromosome 14 at 50,186,768 bp
  • T to C, chromosome 14 at 69,798,178 bp
  • A to G, chromosome 15 at 8,186,560 bp
  • C to T, chromosome 15 at 27,818,071 bp
  • T to A, chromosome 15 at 73,124,240 bp
  • T to C, chromosome 15 at 75,891,477 bp
  • A to G, chromosome 15 at 78,344,566 bp
  • A to G, chromosome 15 at 83,896,115 bp
  • A to T, chromosome 15 at 96,424,662 bp
  • T to C, chromosome 16 at 32,407,863 bp
  • T to A, chromosome 17 at 12,398,114 bp
  • C to T, chromosome 17 at 14,680,388 bp
  • T to C, chromosome 17 at 86,099,268 bp
  • T to C, chromosome 18 at 37,974,370 bp
  • T to C, chromosome 19 at 40,597,479 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6166 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044312-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.