Strain Name:
C57BL/6J-MtgxR6171Btlr/Mmmh
Stock Number:
044314-MU
Citation ID:
RRID:MMRRC_044314-MU
Other Names:
R6171 (G1)
Major Collection:

Gene Information

Pdyn
Name: prodynorphin
Synonyms: Dyn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18610
HGNC: HGNC:8820
Homologene: 10321
Pax2
Name: paired box 2
Synonyms: Pax-2, Opdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18504
HGNC: HGNC:8616
Homologene: 2968
Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: SWAP2, Sfrs16, Srsf16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53609
Homologene: 134306
Serpina9
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
Synonyms: Centerin, 2310014L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71907
Homologene: 23633
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: nonmuscle myosin heavy chain II-B, NMHC-B, SMemb, nonmuscle myosin heavy chain IIB, 9330167F11Rik, 5730504C04Rik, Myhn2, Myosin IIB, NMHC II-B, Myhn-2, myosin IIB, Fltn, Fltn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Kif1b
Name: kinesin family member 1B
Synonyms: D4Mil1e, Kif1b alpha, Kif1b beta, KIF1Bp130, KIF1Bp204, N-3 kinesin, A530096N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16561
Homologene: 99835
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Psmd12
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
Synonyms: P55, 1500002F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66997
HGNC: HGNC:9557
Homologene: 2109
Dnttip2
Name: deoxynucleotidyltransferase, terminal, interacting protein 2
Synonyms: 4930588M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99480
Homologene: 124162
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215113
Homologene: 17555
Rplp0
Name: ribosomal protein, large, P0
Synonyms: 36B4, Arbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11837
Homologene: 6517
Creb3l1
Name: cAMP responsive element binding protein 3-like 1
Synonyms: BBF-2 (drosophila) homolog, Oasis
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26427
Homologene: 8058
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99003
Homologene: 11710
C87436
Name: expressed sequence C87436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232196
Homologene: 9897
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218333
VEGA: 13
Homologene: 18902
Ppp1r13l
Name: protein phosphatase 1, regulatory subunit 13 like
Synonyms: NFkB interacting protein 1, wa3, IASPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 333654
Homologene: 84635
Peg10
Name: paternally expressed 10
Synonyms: MEF3L, HB-1, MyEF-3, MyEF-3 like, Edr, Mart2, Mar2, Rtl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170676
Homologene: 116067
Trim29
Name: tripartite motif-containing 29
Synonyms: 2810431N19Rik, 4732461M22Rik, 1110047J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72169
VEGA: 9
Homologene: 8100
Zbtb5
Name: zinc finger and BTB domain containing 5
Synonyms: 9430083K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230119
Homologene: 8913
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: D7Ertd565e, Nalp9a, Nalp-theta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233001
Homologene: 116072
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Raf, Afr-1, Afr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 387609
Homologene: 8968
Sis
Name: sucrase isomaltase (alpha-glucosidase)
Synonyms: Si-s, sucrase-isomaltase, 2010204N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69983
Homologene: 37424
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: ESTM15, 1810073P09Rik, X83337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75607
Homologene: 19155
Osbp2
Name: oxysterol binding protein 2
Synonyms: OSBPL1, ORP-4, 1700095P05Rik, C630001G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74309
HGNC: HGNC:8504
Homologene: 75303
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Sez4, Rev
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Rab7b
Name: RAB7B, member RAS oncogene family
Synonyms: Rab7b, 5430435G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226421
Homologene: 64833
Adprs
Name: ADP-ribosylserine hydrolase
Synonyms: Arh3, Adprhl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100206
Homologene: 9863
Atp11a
Name: ATPase, class VI, type 11A
Synonyms: Ih, 4930558F19Rik, 9130422H11Rik, LOC100045280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50770
Homologene: 75050
Nek4
Name: NIMA (never in mitosis gene a)-related expressed kinase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 23955
VEGA: 14
Homologene: 2376
Nphp4
Name: nephronophthisis 4 (juvenile) homolog (human)
Synonyms: 4930564O18Rik, nmf192
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 260305
Homologene: 9024
Dyrk1b
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
Elk3
Name: ELK3, member of ETS oncogene family
Synonyms: Erp, Sap-2, Net, D430049E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13713
HGNC: HGNC:3325
Homologene: 3833
Xylb
Name: xylulokinase homolog (H. influenzae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102448
VEGA: 9
Homologene: 3746
Dapl1
Name: death associated protein-like 1
Synonyms: EEDA, 2310032F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76747
Homologene: 18947
Vmn2r24
Name: vomeronasal 2, receptor 24
Synonyms: EG243628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243628
Homologene: 135915
Gm10322
Name: predicted gene 10322
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100039225
Sp110
Name: Sp110 nuclear body protein
Synonyms: 52kDa, Ipr1, 5830484A20Rik, 5031415C07Rik, Ifi75
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Stard13
Name: StAR-related lipid transfer (START) domain containing 13
Synonyms: GT650, DLC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243362
Homologene: 64844
Or8c17
Name: olfactory receptor family 8 subfamily C member 17
Synonyms: GA_x6K02T2PVTD-31962461-31963411, MOR170-1, Olfr895
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258875
Homologene: 74253
Or12e1
Name: olfactory receptor family 12 subfamily E member 1
Synonyms: GA_x6K02T2Q125-48676316-48677272, MOR264-6, Olfr1112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258655
Homologene: 64901
Kcna1
Name: potassium voltage-gated channel, shaker-related subfamily, member 1
Synonyms: Kv1.1, mouse brain potassium channel protein-1, MBK1, Shak, Mk-1, mceph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16485
HGNC: HGNC:6218
Homologene: 183
Nemp1
Name: nuclear envelope integral membrane protein 1
Synonyms: Tmem194
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 210035
Homologene: 18346
Mettl17
Name: methyltransferase like 17
Synonyms: 2310032K15Rik, D14Ertd209e, Mett11d1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 52535
Homologene: 11226
Galt
Name: galactose-1-phosphate uridyl transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14430
HGNC: HGNC:4135
Homologene: 126
Klf15
Name: Kruppel-like factor 15
Synonyms: KKLF, CKLF, 1810013I09Rik, hlb444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66277
Homologene: 8553
Prr23a3
Name: proline rich 23A, member 3
Synonyms: 2410012M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71979
Homologene: 67036
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 85,577,329 bp
  • A to G, chromosome 1 at 131,698,634 bp
  • C to A, chromosome 2 at 59,496,602 bp
  • T to A, chromosome 2 at 87,192,365 bp
  • G to T, chromosome 2 at 91,991,269 bp
  • A to T, chromosome 2 at 104,789,283 bp
  • A to T, chromosome 2 at 129,688,348 bp
  • G to A, chromosome 3 at 72,961,027 bp
  • T to A, chromosome 3 at 122,278,862 bp
  • C to T, chromosome 4 at 41,757,541 bp
  • T to C, chromosome 4 at 44,994,119 bp
  • A to G, chromosome 4 at 126,317,317 bp
  • T to C, chromosome 4 at 149,258,048 bp
  • T to C, chromosome 4 at 152,544,449 bp
  • A to G, chromosome 5 at 115,561,160 bp
  • A to T, chromosome 5 at 151,092,762 bp
  • GAT to GATCAT, chromosome 6 at 4,756,449 bp
  • A to C, chromosome 6 at 86,445,467 bp
  • G to T, chromosome 6 at 90,466,619 bp
  • T to C, chromosome 6 at 123,787,246 bp
  • A to T, chromosome 6 at 126,642,323 bp
  • A to G, chromosome 7 at 19,377,511 bp
  • T to C, chromosome 7 at 19,584,822 bp
  • T to C, chromosome 7 at 26,558,763 bp
  • A to T, chromosome 7 at 28,186,550 bp
  • T to A, chromosome 8 at 12,832,663 bp
  • C to T, chromosome 9 at 38,268,602 bp
  • G to A, chromosome 9 at 43,319,377 bp
  • C to T, chromosome 9 at 95,881,271 bp
  • T to A, chromosome 9 at 98,865,678 bp
  • C to T, chromosome 9 at 119,381,591 bp
  • T to A, chromosome 10 at 39,862,713 bp
  • T to C, chromosome 10 at 59,616,262 bp
  • G to T, chromosome 10 at 93,250,044 bp
  • T to A, chromosome 10 at 127,689,450 bp
  • A to T, chromosome 11 at 3,717,221 bp
  • G to A, chromosome 11 at 68,791,890 bp
  • A to T, chromosome 11 at 69,423,042 bp
  • A to G, chromosome 11 at 75,563,050 bp
  • T to C, chromosome 11 at 107,491,907 bp
  • G to T, chromosome 12 at 104,008,419 bp
  • T to C, chromosome 13 at 49,060,832 bp
  • T to C, chromosome 13 at 70,606,731 bp
  • T to C, chromosome 14 at 30,970,347 bp
  • T to A, chromosome 14 at 51,888,779 bp
  • A to G, chromosome 15 at 57,823,206 bp
  • A to G, chromosome 19 at 44,790,740 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6171 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044314-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.