Strain Name:
C57BL/6J-MtgxR6172Btlr/Mmmh
Stock Number:
044315-MU
Citation ID:
RRID:MMRRC_044315-MU
Other Names:
R6172 (G1)
Major Collection:

Gene Information

Ubn2
Name: ubinuclein 2
Synonyms: 6030408G03Rik, 2900060J04Rik, D130059P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320538
Homologene: 45564
Itga6
Name: integrin alpha 6
Synonyms: Cd49f, 5033401O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16403
HGNC: HGNC:6142
Homologene: 20091
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 0610038M01Rik, 2610510B01Rik, Dopey2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20513
VEGA: 10
Homologene: 21055
Sdhc
Name: succinate dehydrogenase complex, subunit C, integral membrane protein
Synonyms: 0610010E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66052
Homologene: 2256
Slc29a1
Name: solute carrier family 29 (nucleoside transporters), member 1
Synonyms: ENT1, NBMPR-sensitive equilibrative nucleoside transporter, 1200014D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 63959
Homologene: 37985
Srgap2
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: FBP2, 9930124L22Rik, Fnbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14270
Homologene: 52683
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, 4930432B04Rik, D730027C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75786
Homologene: 8844
Enox1
Name: ecto-NOX disulfide-thiol exchanger 1
Synonyms: D230005D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239188
VEGA: 14
Homologene: 56793
Prc1
Name: protein regulator of cytokinesis 1
Synonyms: D7Ertd348e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233406
HGNC: HGNC:9341
Homologene: 37868
Ngdn
Name: neuroguidin, EIF4E binding protein
Synonyms: neuroguidin, 1500001L15Rik, Ngd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68966
VEGA: 14
Homologene: 44286
Wdr26
Name: WD repeat domain 26
Synonyms: 1600024A01Rik, Gid7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226757
Homologene: 11857
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: mGluR7, Gpr1g, E130018M02Rik, 6330570A01Rik, mGlu7a receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: C530005A01Rik, 6030465E24Rik, spastic paraplegia 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214585
Homologene: 41614
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: Dbs, C130040G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17207
Homologene: 11804
Macrod2
Name: mono-ADP ribosylhydrolase 2
Synonyms: 2610107G07Rik, 1110033L15Rik, 2900006F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72899
Homologene: 85987
Notch1
Name: notch 1
Synonyms: lin-12, Tan1, Mis6, 9930111A19Rik, Motch A, N1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18128
HGNC: HGNC:7881
Homologene: 32049
D11Wsu47e
Name: DNA segment, Chr 11, Wayne State University 47, expressed
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276852
Homologene: 9928
Hacd3
Name: 3-hydroxyacyl-CoA dehydratase 3
Synonyms: B-ind1, Hspc121, Ptplad1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57874
VEGA: 9
Homologene: 9494
Osbpl10
Name: oxysterol binding protein-like 10
Synonyms: 4933433D06Rik, OPR-10, C820004B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74486
Homologene: 69240
Emc1
Name: ER membrane protein complex subunit 1
Synonyms: C230096C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230866
Homologene: 9002
Gtf3c2
Name: general transcription factor IIIC, polypeptide 2, beta
Synonyms: 2610510G03Rik, TFIIIC-BETA, TFIIIC110, 1300004C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71752
HGNC: HGNC:4665
Homologene: 37490
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Uckl1
Name: uridine-cytidine kinase 1-like 1
Synonyms: 1110007H10Rik, Urkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68556
Homologene: 101414
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240411
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Cracr2b
Name: calcium release activated channel regulator 2B
Synonyms: 6330520A15Rik, Efcab4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 213573
Homologene: 45468
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Pabpc6
Name: poly(A) binding protein, cytoplasmic 6
Synonyms: 4932702K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67543
VEGA: 17
HGNC: HGNC:8554
Homologene: 129776
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319482
Homologene: 130055
Pcdhb13
Name: protocadherin beta 13
Synonyms: PcdhbM, Pcdbh6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93884
HGNC: HGNC:8691
Homologene: 10338
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235505
Homologene: 25183
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230622
Homologene: 135888
Tigd4
Name: tigger transposable element derived 4
Synonyms: Tigd4, C130063O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 403175
Homologene: 131124
Gsta5
Name: glutathione S-transferase alpha 5
Synonyms: Gm10639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100042314
Homologene: 74378
Pde6c
Name: phosphodiesterase 6C, cGMP specific, cone, alpha prime
Synonyms: cpfl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 110855
VEGA: 19
HGNC: HGNC:8787
Homologene: 4521
Or14c46
Name: olfactory receptor family 14 subfamily C member 46
Synonyms: GA_x6K02T2NHDJ-9838699-9839697, MOR227-6P, Olfr310
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258222
Homologene: 128066
Pou3f2
Name: POU domain, class 3, transcription factor 2
Synonyms: Brn-2, Otf7, Brn2, 9430075J19Rik, A230098E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18992
HGNC: HGNC:9215
Homologene: 4095
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277360
Homologene: 10821
Rimklb
Name: ribosomal modification protein rimK-like family member B
Synonyms: 4931417E21Rik, 4933426K21Rik, NAAGS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108653
Homologene: 18968
Or5d14
Name: olfactory receptor family 5 subfamily D member 14
Synonyms: GA_x6K02T2Q125-49542541-49541597, MOR174-14, Olfr1162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258105
Homologene: 79476
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Vmn2r24
Name: vomeronasal 2, receptor 24
Synonyms: EG243628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243628
Homologene: 135915
Radil
Name: Ras association and DIL domains
Synonyms: D930005D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231858
Homologene: 77648
Bco1
Name: beta-carotene oxygenase 1
Synonyms: beta-CD, Bcdo, Bcdo1, betaCMOOX, Cmoi, Bcmo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 63857
Homologene: 41172
Zfp39
Name: zinc finger protein 39
Synonyms: CTfin33, Zfp-39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22698
Homologene: 69102
4930590J08Rik
Name: RIKEN cDNA 4930590J08 gene
Synonyms: LOC381798
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381798
Homologene: 49985
H4c9
Name: H4 clustered histone 9
Synonyms: Hist1h4i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319158
Homologene: 134468
Msgn1
Name: mesogenin 1
Synonyms: Msgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56184
VEGA: 12
Homologene: 10466
Or1a1b
Name: olfactory receptor family 1 subfamily A member 1B
Synonyms: MOR125-1, GA_x6K02T2P1NL-4359899-4358958, Olfr43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258706
Homologene: 8219
Pofut1
Name: protein O-fucosyltransferase 1
Synonyms: O-FucT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140484
Homologene: 9104
Zc3h8
Name: zinc finger CCCH type containing 8
Synonyms: E130108N08Rik, Fliz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57432
Homologene: 10759
Foxa1
Name: forkhead box A1
Synonyms: Tcf-3a, Hnf-3a, Tcf3a, Hnf3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 15375
VEGA: 12
HGNC: HGNC:5021
Homologene: 3307
Slfn14
Name: schlafen 14
Synonyms: LOC237890, Slfn14-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237890
Homologene: 19082
Amica1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Gm10081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 131,289,616 bp
  • G to A, chromosome 1 at 150,646,784 bp
  • A to T, chromosome 1 at 171,138,702 bp
  • G to A, chromosome 1 at 181,191,868 bp
  • C to T, chromosome 2 at 26,485,442 bp
  • T to C, chromosome 2 at 41,449,263 bp
  • A to G, chromosome 2 at 71,833,709 bp
  • A to T, chromosome 2 at 88,050,302 bp
  • A to G, chromosome 2 at 91,568,219 bp
  • A to T, chromosome 2 at 122,086,805 bp
  • C to A, chromosome 2 at 128,943,855 bp
  • G to T, chromosome 2 at 140,400,975 bp
  • C to T, chromosome 2 at 153,259,616 bp
  • A to G, chromosome 2 at 166,572,963 bp
  • C to T, chromosome 2 at 181,573,073 bp
  • A to G, chromosome 3 at 84,595,267 bp
  • T to C, chromosome 4 at 22,486,960 bp
  • T to A, chromosome 4 at 112,839,313 bp
  • T to C, chromosome 4 at 131,785,754 bp
  • T to C, chromosome 4 at 139,366,531 bp
  • G to A, chromosome 4 at 144,975,193 bp
  • G to A, chromosome 5 at 31,158,211 bp
  • A to G, chromosome 5 at 142,487,115 bp
  • G to A, chromosome 6 at 38,461,536 bp
  • T to A, chromosome 6 at 91,942,536 bp
  • T to A, chromosome 6 at 111,246,297 bp
  • A to G, chromosome 6 at 122,456,412 bp
  • A to T, chromosome 6 at 123,816,277 bp
  • A to G, chromosome 7 at 28,139,959 bp
  • G to A, chromosome 7 at 80,304,796 bp
  • A to T, chromosome 7 at 86,268,801 bp
  • A to T, chromosome 7 at 107,106,507 bp
  • T to A, chromosome 7 at 141,464,836 bp
  • G to A, chromosome 8 at 13,013,849 bp
  • T to A, chromosome 8 at 117,113,534 bp
  • T to C, chromosome 9 at 45,088,773 bp
  • G to A, chromosome 9 at 54,393,727 bp
  • T to C, chromosome 9 at 65,005,627 bp
  • T to A, chromosome 9 at 78,304,455 bp
  • G to A, chromosome 9 at 78,665,546 bp
  • A to G, chromosome 9 at 115,109,487 bp
  • T to A, chromosome 10 at 78,801,907 bp
  • A to G, chromosome 11 at 58,891,387 bp
  • A to T, chromosome 11 at 74,206,640 bp
  • A to T, chromosome 11 at 83,276,603 bp
  • C to A, chromosome 11 at 113,688,975 bp
  • A to G, chromosome 12 at 11,208,923 bp
  • A to G, chromosome 12 at 57,542,900 bp
  • T to A, chromosome 13 at 22,041,077 bp
  • A to T, chromosome 14 at 31,162,519 bp
  • C to A, chromosome 14 at 55,022,099 bp
  • T to C, chromosome 14 at 77,508,187 bp
  • T to C, chromosome 16 at 18,794,704 bp
  • T to G, chromosome 16 at 93,766,222 bp
  • G to A, chromosome 17 at 9,668,155 bp
  • A to T, chromosome 17 at 45,589,928 bp
  • A to T, chromosome 18 at 37,443,421 bp
  • C to A, chromosome 18 at 54,988,544 bp
  • T to C, chromosome 18 at 77,412,178 bp
  • T to C, chromosome 19 at 38,140,229 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6172 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044315-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.