Strain Name:
C57BL/6J-MtgxR6173Btlr
Stock Number:
044316-MU
Citation ID:
RRID:MMRRC_044316-MU
Other Names:
R6173 (G1)
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: Gm4392, Ank-2, Ankyrin-2, Ankyrin-B, ankyrin B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Strn
Name: striatin, calmodulin binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268980
Homologene: 2380
Mfap4
Name: microfibrillar-associated protein 4
Synonyms: 1110007F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76293
HGNC: HGNC:7035
Homologene: 134529
Foxp1
Name: forkhead box P1
Synonyms: 3110052D19Rik, 4932443N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108655
HGNC: HGNC:3823
Homologene: 13092
Gid4
Name: GID complex subunit 4, VID24 homolog
Synonyms: 4933439F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66771
Homologene: 5971
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: D930043C02Rik, Rnf164, 9430019J22Rik, 2900024N03Rik, Mnab
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319817
Homologene: 28276
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: WSTF, Wbscr9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Safb
Name: scaffold attachment factor B
Synonyms: 5330423C17Rik, SAFB1, 3110021E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224903
Homologene: 2229
Sart3
Name: squamous cell carcinoma antigen recognized by T cells 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 53890
Homologene: 40977
Bend3
Name: BEN domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 331623
VEGA: 10
Homologene: 19511
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212285
Homologene: 9064
Parn
Name: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: DAN, 1200003I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74108
VEGA: 16
HGNC: HGNC:8609
Homologene: 31098
Esr1
Name: estrogen receptor 1 (alpha)
Synonyms: Estra, Estr, ERa, ER-alpha, ERalpha, ESR, ER[a], Nr3a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13982
HGNC: HGNC:3467
Homologene: 47906
Rad17
Name: RAD17 checkpoint clamp loader component
Synonyms: MmRad24, 9430035O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19356
VEGA: 13
HGNC: HGNC:9807
Homologene: 32117
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 209018
Homologene: 44592
Ptprc
Name: protein tyrosine phosphatase, receptor type, C
Synonyms: Lyt-4, CD45, B220, Ly-5, T200
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Mfsd2a
Name: major facilitator superfamily domain containing 2A
Synonyms: 1700018O18Rik, Mfsd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76574
Homologene: 19229
Zfp998
Name: zinc finger protein 998
Synonyms: 2410141K09Rik, Gt(pU21)35Imeg, Gt(Ayu21)35Imeg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76803
Homologene: 136362
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: Hch, MBC, CED-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: 1700048H13Rik, STAMP, 4930556H18Rik, 2310009M18Rik, D630041K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320244
Homologene: 9013
Sohlh2
Name: spermatogenesis and oogenesis specific basic helix-loop-helix 2
Synonyms: 4933406N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74434
Homologene: 9864
Trp73
Name: transformation related protein 73
Synonyms: TAp73, p73, deltaNp73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22062
Homologene: 3960
Tespa1
Name: thymocyte expressed, positive selection associated 1
Synonyms: Itprid3, 5830405N20Rik, A430001F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67596
VEGA: 10
Homologene: 106645
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68591
VEGA: 18
Homologene: 9931
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Chia1
Name: chitinase, acidic 1
Synonyms: Chia, YNL, AMCase, 2200003E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81600
Homologene: 75168
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: Dnahcl1, Dnahc17, LOC382552, 2810003K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Bbs7
Name: Bardet-Biedl syndrome 7 (human)
Synonyms: 8430406N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71492
Homologene: 12395
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG620718, EG667069
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 667069
Homologene: 129754
Tbx15
Name: T-box 15
Synonyms: Tbx14, de, Tbx8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21384
Homologene: 7967
Slc13a5
Name: solute carrier family 13 (sodium-dependent citrate transporter), member 5
Synonyms: NaC2/NaCT, Indy, mINDY, Nact
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237831
Homologene: 21941
Fshb
Name: follicle stimulating hormone beta
Synonyms: Fshbeta, FSH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14308
HGNC: HGNC:3964
Homologene: 430
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: Nalp2, E330007A02Rik, Nbs1, Pan1, PYPAF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Cadm2
Name: cell adhesion molecule 2
Synonyms: 2900078E11Rik, Igsf4d, A830029E02Rik, Necl3, SynCAM2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239857
Homologene: 17705
Olfr1346
Name: olfactory receptor 1346
Synonyms: MOR103-6, GA_x6K02T2QGBW-3203957-3204898
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258918
Homologene: 74134
F830045P16Rik
Name: RIKEN cDNA F830045P16 gene
Synonyms: Sirpb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228592
Homologene: 136180
Dazl
Name: deleted in azoospermia-like
Synonyms: Dazla, Tpx-2, Daz-like, Tpx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13164
VEGA: 17
Homologene: 86954
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: 4930532L22Rik, B230399N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269610
Homologene: 56712
Mrto4
Name: mRNA turnover 4, ribosome maturation factor
Synonyms: Mrt4, 2610012O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69902
Homologene: 6379
Gm14412
Name: predicted gene 14412
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 102640477
Homologene: 134324
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Clpx
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270166
HGNC: HGNC:2088
Homologene: 4851
Galk2
Name: galactokinase 2
Synonyms: 2810017M24Rik, Gk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69976
HGNC: HGNC:4119
Homologene: 13654
Zp3r
Name: zona pellucida 3 receptor
Synonyms: SP56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22789
Homologene: 7609
Olfr738
Name: olfactory receptor 738
Synonyms: MOR106-3, GA_x6K02T2PMLR-6110726-6111661
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258662
Homologene: 74220
Utp14b
Name: UTP14B small subunit processome component
Synonyms: 4932411L21Rik, jsd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 195434
Homologene: 78703
Ch25h
Name: cholesterol 25-hydroxylase
Synonyms: m25OH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12642
VEGA: 19
HGNC: HGNC:1907
Homologene: 2942
Olfr1388
Name: olfactory receptor 1388
Synonyms: MOR256-28, GA_x6K02T2QP88-5991012-5990077
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258459
Homologene: 74258
Vmn2r29
Name: vomeronasal 2, receptor 29
Synonyms: 6430701C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76229
Homologene: 113703
Olfr360
Name: olfactory receptor 360
Synonyms: GA_x6K02T2NLDC-33760081-33761034, MOR159-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258615
Homologene: 73997
Zfp36l1
Name: zinc finger protein 36, C3H type-like 1
Synonyms: TIS11b, D530020L18Rik, cMG1, Brf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 12192
VEGA: 12
HGNC: HGNC:1107
Homologene: 31276
Iqank1
Name: IQ motif and ankyrin repeat containing 1
Synonyms: K230010J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 432964
Homologene: 141000
Mup20
Name: major urinary protein 20
Synonyms: darcin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381530
Homologene: 74304
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 78,665,837 bp
  • A to C, chromosome 1 at 78,665,840 bp
  • A to T, chromosome 1 at 130,591,568 bp
  • A to C, chromosome 1 at 138,067,890 bp
  • A to G, chromosome 2 at 37,069,079 bp
  • GCC to GCCC, chromosome 2 at 37,414,733 bp
  • T to C, chromosome 2 at 107,057,293 bp
  • A to G, chromosome 2 at 125,859,217 bp
  • A to G, chromosome 2 at 129,463,668 bp
  • G to A, chromosome 2 at 177,314,537 bp
  • A to T, chromosome 3 at 36,592,374 bp
  • G to T, chromosome 3 at 55,196,998 bp
  • G to C, chromosome 3 at 64,559,755 bp
  • G to T, chromosome 3 at 99,253,887 bp
  • T to C, chromosome 3 at 106,129,022 bp
  • T to C, chromosome 3 at 127,052,746 bp
  • A to T, chromosome 4 at 62,054,030 bp
  • T to A, chromosome 4 at 83,473,049 bp
  • T to C, chromosome 4 at 113,535,710 bp
  • A to G, chromosome 4 at 122,951,246 bp
  • T to C, chromosome 4 at 139,350,444 bp
  • A to T, chromosome 4 at 152,379,391 bp
  • A to T, chromosome 4 at 154,104,341 bp
  • A to T, chromosome 5 at 62,749,622 bp
  • C to T, chromosome 5 at 113,743,206 bp
  • T to C, chromosome 5 at 135,242,507 bp
  • G to A, chromosome 6 at 99,015,510 bp
  • C to A, chromosome 6 at 99,015,514 bp
  • T to A, chromosome 6 at 121,863,793 bp
  • T to C, chromosome 7 at 5,337,809 bp
  • C to T, chromosome 7 at 6,474,836 bp
  • T to C, chromosome 7 at 7,231,370 bp
  • C to A, chromosome 9 at 65,301,879 bp
  • T to C, chromosome 10 at 4,746,760 bp
  • A to G, chromosome 10 at 43,509,868 bp
  • A to G, chromosome 10 at 130,347,303 bp
  • T to C, chromosome 11 at 34,262,388 bp
  • T to C, chromosome 11 at 49,444,472 bp
  • A to G, chromosome 11 at 60,432,415 bp
  • A to G, chromosome 11 at 61,485,419 bp
  • C to T, chromosome 11 at 72,253,197 bp
  • A to G, chromosome 11 at 118,039,946 bp
  • A to T, chromosome 12 at 80,109,546 bp
  • A to T, chromosome 12 at 85,933,377 bp
  • T to A, chromosome 13 at 66,431,549 bp
  • A to C, chromosome 13 at 100,622,881 bp
  • A to G, chromosome 14 at 50,414,197 bp
  • A to G, chromosome 15 at 76,045,388 bp
  • T to C, chromosome 16 at 13,651,811 bp
  • T to G, chromosome 16 at 21,495,932 bp
  • A to G, chromosome 16 at 32,736,140 bp
  • C to T, chromosome 16 at 66,882,841 bp
  • A to T, chromosome 17 at 50,287,571 bp
  • A to G, chromosome 17 at 56,597,798 bp
  • A to G, chromosome 17 at 78,700,869 bp
  • A to T, chromosome 18 at 24,676,582 bp
  • A to G, chromosome 19 at 34,474,496 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6173 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044316-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.