Strain Name:
C57BL/6J-MtgxR6196Btlr/Mmmh
Stock Number:
044336-MU
Citation ID:
RRID:MMRRC_044336-MU
Other Names:
R6196 (G1)
Major Collection:

Gene Information

Lgi1
Name: leucine-rich repeat LGI family, member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56839
HGNC: HGNC:6572
Homologene: 3737
Slc27a4
Name: solute carrier family 27 (fatty acid transporter), member 4
Synonyms: fatty acid transport protein 4, FATP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26569
Homologene: 68437
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66860
Homologene: 18946
Ctdspl2
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
Synonyms: D2Ertd485e, SCP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329506
Homologene: 32311
Lemd2
Name: LEM domain containing 2
Synonyms: Lem2, NET25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224640
VEGA: 17
Homologene: 17136
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: 5033407O22Rik, 4833414K03Rik, CHAK1, CHAK, TRP-PLIK, Ltpr7, 2310022G15Rik, LTRPC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58800
Homologene: 9774
Fbxo28
Name: F-box protein 28
Synonyms: 5730505P19Rik, 4833428J17Rik, Fbx28, D1Ertd578e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67948
Homologene: 9050
Uhrf1bp1l
Name: UHRF1 (ICBP90) binding protein 1-like
Synonyms: 4930506D01Rik, 2010319N22Rik, E030041M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 75089
VEGA: 10
Homologene: 12590
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: PEPP2, 2810431N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109135
Homologene: 10377
Cc2d1b
Name: coiled-coil and C2 domain containing 1B
Synonyms: A830039B04Rik, Freud2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 319965
Homologene: 70951
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: Sin3, mSin3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20466
Homologene: 32124
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215113
Homologene: 17555
Pus10
Name: pseudouridylate synthase 10
Synonyms: 2810013G11Rik, 4933435A13Rik, Ccdc139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74467
Homologene: 12566
Asb4
Name: ankyrin repeat and SOCS box-containing 4
Synonyms: 8430401O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 65255
Homologene: 9392
Tcf20
Name: transcription factor 20
Synonyms: SPBP, stromelysin 1 PDGF responsive element binding protein, 2810438H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21411
VEGA: 15
Homologene: 4131
Rab37
Name: RAB37, member RAS oncogene family
Synonyms: B230331O03Rik, B230354I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58222
Homologene: 23303
Tap2
Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: MTP2, PSF2, Ham2, Ham-2, Tap-2, HAM2, Abcb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21355
HGNC: HGNC:44
Homologene: 37323
Hk1
Name: hexokinase 1
Synonyms: Hk-1, mHk1-s, Hk1-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Extl3
Name: exostosin-like glycosyltransferase 3
Synonyms: 2900009G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54616
VEGA: 14
HGNC: HGNC:3518
Homologene: 1103
Cab39l
Name: calcium binding protein 39-like
Synonyms: 2810425O13Rik, 1500031K13Rik, MO2L, 4930520C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 69008
VEGA: 14
Homologene: 69422
Atp6v1c2
Name: ATPase, H+ transporting, lysosomal V1 subunit C2
Synonyms: 1110038G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68775
Homologene: 15866
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 105242472
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238455
Homologene: 18813
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Syna
Name: syncytin a
Synonyms: syncytin-A, Gm52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 214292
Homologene: 86751
Btn2a2
Name: butyrophilin, subfamily 2, member A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238555
HGNC: HGNC:1137
Homologene: 56012
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628444
Homologene: 129683
Crybg2
Name: crystallin beta-gamma domain containing 2
Synonyms: Aim1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230806
Homologene: 19232
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21974
Homologene: 134711
4933405L10Rik
Name: RIKEN cDNA 4933405L10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71046
Homologene: 19274
T
Name: brachyury, T-box transcription factor T
Synonyms: T1, Bra, Tbxt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20997
Homologene: 2393
Vwc2l
Name: von Willebrand factor C domain-containing protein 2-like
Synonyms: brorin-like, Brl, A830006F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320460
Homologene: 27945
Tcaf1
Name: TRPM8 channel-associated factor 1
Synonyms: A230020K05Rik, 2810407D09Rik, 3321401G04Rik, Fam115a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 77574
Homologene: 8815
Olfr959
Name: olfactory receptor 959
Synonyms: GA_x6K02T2PVTD-33270211-33269276, MOR224-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258501
VEGA: 9
Homologene: 71989
Dynlt5
Name: dynein light chain Tctex-type 5
Synonyms: 1700055O19Rik, Tctex1d1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67344
Homologene: 12117
Acap1
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Synonyms: Centb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216859
Homologene: 22835
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71872
Homologene: 70273
Galc
Name: galactosylceramidase
Synonyms: Gacy, 2310068B06Rik, galactocerebrosidase, A930008M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14420
VEGA: 12
HGNC: HGNC:4115
Homologene: 124
Olfr23
Name: olfactory receptor 23
Synonyms: MTPCR50, GA_x6K02T2P1NL-4097159-4098136, MOR135-27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18321
Homologene: 115483
Olfr730
Name: olfactory receptor 730
Synonyms: GA_x6K02T2PMLR-5881670-5880717, MOR247-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258486
Homologene: 17269
Cenpu
Name: centromere protein U
Synonyms: 1700029A22Rik, Mlf1ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71876
Homologene: 11629
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74682
Homologene: 10814
Cdc14b
Name: CDC14 cell division cycle 14B
Synonyms: 2810432N10Rik, A530086E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218294
VEGA: 13
HGNC: HGNC:1719
Homologene: 104197
Bend6
Name: BEN domain containing 6
Synonyms: B230209C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320705
Homologene: 27394
Acvr2b
Name: activin receptor IIB
Synonyms: ActRIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11481
VEGA: 9
HGNC: HGNC:174
Homologene: 863
Fam162b
Name: family with sequence similarity 162, member B
Synonyms: 9430073N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77296
VEGA: 10
Homologene: 82459
Chit1
Name: chitinase 1 (chitotriosidase)
Synonyms: 2300002L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71884
HGNC: HGNC:1936
Homologene: 68318
Msmo1
Name: methylsterol monoxygenase 1
Synonyms: ERG25, DESP4, 1500001G16Rik, C78600, Sc4mol
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66234
Homologene: 133932
Olfr1
Name: olfactory receptor 1
Synonyms: MOR135-13, GA_x6K02T2P1NL-3556334-3555390, I54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258923
Homologene: 115482
Acyp2
Name: acylphosphatase 2, muscle type
Synonyms: 2310004B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75572
HGNC: HGNC:180
Homologene: 41776
Ctsr
Name: cathepsin R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56835
VEGA: 13
Homologene: 75127
Gm5468
Name: predicted gene 5468
Synonyms: 100040583, Gm48957
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 432939
VEGA: 15
Agr2
Name: anterior gradient 2
Synonyms: mAG-2, Gob-4, XAG-2, HAG-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 23795
HGNC: HGNC:328
Homologene: 4674
Igkv5-45
Name: immunoglobulin kappa chain variable 5-45
Synonyms: Gm16850
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545850
Olfr1464-ps1
Name: olfactory receptor 1464, pseudogene 1
Synonyms: GA_x6K02T2RE5P-3614075-3613153, MOR202-27P, Gm8561
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 667300
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 33,878,428 bp
  • T to A, chromosome 1 at 58,217,526 bp
  • T to A, chromosome 1 at 70,729,021 bp
  • C to A, chromosome 1 at 134,146,643 bp
  • T to C, chromosome 1 at 182,329,889 bp
  • A to G, chromosome 2 at 29,805,750 bp
  • G to A, chromosome 2 at 59,844,022 bp
  • A to C, chromosome 2 at 82,989,883 bp
  • A to G, chromosome 2 at 121,978,892 bp
  • G to A, chromosome 2 at 126,825,639 bp
  • A to G, chromosome 4 at 102,992,569 bp
  • C to T, chromosome 4 at 108,633,225 bp
  • C to A, chromosome 4 at 134,081,139 bp
  • G to T, chromosome 5 at 134,559,612 bp
  • G to A, chromosome 6 at 5,390,699 bp
  • A to T, chromosome 6 at 42,676,807 bp
  • A to G, chromosome 6 at 69,775,981 bp
  • T to C, chromosome 6 at 140,579,453 bp
  • A to G, chromosome 7 at 42,012,255 bp
  • C to A, chromosome 7 at 141,851,596 bp
  • A to G, chromosome 8 at 46,562,580 bp
  • A to G, chromosome 8 at 64,727,884 bp
  • A to T, chromosome 8 at 105,709,922 bp
  • G to A, chromosome 9 at 39,572,480 bp
  • T to A, chromosome 9 at 57,103,929 bp
  • T to C, chromosome 9 at 119,433,403 bp
  • C to A, chromosome 10 at 51,587,410 bp
  • T to A, chromosome 10 at 62,299,259 bp
  • T to G, chromosome 10 at 89,805,333 bp
  • A to G, chromosome 11 at 23,672,638 bp
  • C to T, chromosome 11 at 30,506,354 bp
  • T to C, chromosome 11 at 69,887,067 bp
  • G to A, chromosome 11 at 73,395,473 bp
  • G to A, chromosome 11 at 73,940,809 bp
  • C to T, chromosome 11 at 75,568,380 bp
  • T to G, chromosome 11 at 104,855,560 bp
  • T to C, chromosome 11 at 115,160,306 bp
  • A to G, chromosome 12 at 9,027,632 bp
  • C to A, chromosome 12 at 17,301,186 bp
  • A to T, chromosome 12 at 35,995,592 bp
  • A to T, chromosome 12 at 98,259,162 bp
  • T to G, chromosome 12 at 119,446,050 bp
  • C to T, chromosome 13 at 23,487,845 bp
  • A to T, chromosome 13 at 61,160,531 bp
  • C to T, chromosome 13 at 64,205,524 bp
  • T to G, chromosome 14 at 16,409,189 bp
  • C to A, chromosome 14 at 50,186,678 bp
  • T to A, chromosome 14 at 59,499,590 bp
  • T to A, chromosome 14 at 65,076,135 bp
  • A to G, chromosome 15 at 25,414,395 bp
  • G to T, chromosome 15 at 82,851,986 bp
  • A to G, chromosome 17 at 8,437,164 bp
  • G to A, chromosome 17 at 27,193,002 bp
  • C to A, chromosome 17 at 34,214,410 bp
  • A to G, chromosome 19 at 13,282,926 bp
  • A to G, chromosome 19 at 38,305,809 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6196 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044336-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.