Strain Name:
C57BL/6J-MtgxR6210Btlr
Stock Number:
044344-MU
Citation ID:
RRID:MMRRC_044344-MU
Other Names:
R6210 (G1)
Major Collection:

Gene Information

Itga6
Name: integrin alpha 6
Synonyms: Cd49f, 5033401O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16403
HGNC: HGNC:6142
Homologene: 20091
Ilrun
Name: inflammation and lipid regulator with UBA-like and NBR1-like domains
Synonyms: D17Wsu92e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224647
Homologene: 32575
Frrs1
Name: ferric-chelate reductase 1
Synonyms: Sdfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20321
Homologene: 40653
Uhmk1
Name: U2AF homology motif (UHM) kinase 1
Synonyms: KIS, Kist, OTTMUSG00000021542, C820018A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16589
Homologene: 7801
Ung
Name: uracil DNA glycosylase
Synonyms: UNG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22256
Homologene: 6585
Rfx1
Name: regulatory factor X, 1 (influences HLA class II expression)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19724
HGNC: HGNC:9982
Homologene: 2189
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: MICAL-3, C130040D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194401
Homologene: 85288
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233532
Homologene: 41142
Serbp1
Name: serpine1 mRNA binding protein 1
Synonyms: 9330147J08Rik, 1200009K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66870
Homologene: 134277
Dctn4
Name: dynactin 4
Synonyms: p62, 4930547K17Rik, 1110001K06Rik, C130039E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67665
VEGA: 18
Homologene: 9430
Cep135
Name: centrosomal protein 135
Synonyms: LOC381644, Cep4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381644
Homologene: 45709
Abhd3
Name: abhydrolase domain containing 3
Synonyms: LABH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106861
Homologene: 14055
Lig4
Name: ligase IV, DNA, ATP-dependent
Synonyms: DNA ligase IV, 5830471N16Rik, tiny
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319583
HGNC: HGNC:6601
Homologene: 1736
Pah
Name: phenylalanine hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18478
HGNC: HGNC:8582
Homologene: 234
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: Mpr300, CI-MPR, IGF-II/CI-MPR, M6P/IGF2R, CD222, mannose-6-phosphate receptor, cation independent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Nr6a1
Name: nuclear receptor subfamily 6, group A, member 1
Synonyms: Gcnf, NCNF, 1700113M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14536
HGNC: HGNC:7985
Homologene: 36308
Zfp748
Name: zinc finger protein 748
Synonyms: 2610014M12Rik, mszf54, KRAB-O, Zfp208
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 212276
Homologene: 134552
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71409
Homologene: 70871
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Pced1a
Name: PC-esterase domain containing 1A
Synonyms: A930025D01Rik, Fam113a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319513
Homologene: 11241
Ccdc127
Name: coiled-coil domain containing 127
Synonyms: 5430420E17Rik, 0610011N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67433
Homologene: 11482
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Hephl1
Name: hephaestin-like 1
Synonyms: LOC244698, Zp, zyklopen, thd, cw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244698
Homologene: 9112
Usp17le
Name: ubiquitin specific peptidase 17-like E
Synonyms: Gm6596, Dub3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 625530
Homologene: 131315
Bbox1
Name: butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170442
HGNC: HGNC:964
Homologene: 2967
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: 2410066K11Rik, line 158, Thm1, aln
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73668
Homologene: 57006
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Cd101
Name: CD101 antigen
Synonyms: LOC381460, Igsf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Megf8
Name: multiple EGF-like-domains 8
Synonyms: Egfl4, b2b288Clo, b2b1702Clo, m687Ddg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Vmn2r84
Name: vomeronasal 2, receptor 84
Synonyms: EG625068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625068
Homologene: 129606
Upk3bl
Name: uroplakin 3B-like
Synonyms: 2310043J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69665
Homologene: 78581
Lmod3
Name: leiomodin 3 (fetal)
Synonyms: 5430424A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320502
HGNC: HGNC:6649
Homologene: 28097
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627743
Homologene: 129680
Psg21
Name: pregnancy-specific glycoprotein 21
Synonyms: cea8, 1600019C01Rik, 1600026N13Rik, 1600025N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72242
Homologene: 110989
Hinfp
Name: histone H4 transcription factor
Synonyms: DKFZp434F162, Mizf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102423
VEGA: 9
Homologene: 9174
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Ceacam15
Name: carcinoembryonic antigen-related cell adhesion molecule 15
Synonyms: C430002N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101434
Homologene: 131210
Kcnip1
Name: Kv channel-interacting protein 1
Synonyms: 2900046L02Rik, KCHIP1, 3202002F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70357
Homologene: 22824
Raet1d
Name: retinoic acid early transcript delta
Synonyms: RAE-1delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56554
Homologene: 134115
Pdzrn4
Name: PDZ domain containing RING finger 4
Synonyms: SAMCAP3L, LNX4, 1110017D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239618
VEGA: 15
Homologene: 85433
Tlr1
Name: toll-like receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21897
Homologene: 20694
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 236193
Homologene: 136795
Cxcr6
Name: chemokine (C-X-C motif) receptor 6
Synonyms: STRL33, BONZO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80901
VEGA: 9
Homologene: 38197
Msi1
Name: musashi RNA-binding protein 1
Synonyms: m-Msi-1, Musahi1, Msi1, Msi1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17690
HGNC: HGNC:7330
Homologene: 55657
Itga3
Name: integrin alpha 3
Synonyms: VLA-3 alpha 3, alpha3-integrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16400
HGNC: HGNC:6139
Homologene: 21129
Olfr1056
Name: olfactory receptor 1056
Synonyms: GA_x6K02T2Q125-47827833-47826892, MOR186-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259020
Homologene: 27328
Catsperb
Name: cation channel sperm associated auxiliary subunit beta
Synonyms: 4932415G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 271036
VEGA: 12
Homologene: 81904
Olfr330
Name: olfactory receptor 330
Synonyms: GA_x6K02T2NKPP-895420-896349, MOR275-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258879
Homologene: 133015
Rnase2a
Name: ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)
Synonyms: Ear11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 93726
VEGA: 14
Homologene: 121614
Gpr157
Name: G protein-coupled receptor 157
Synonyms: F730108M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269604
Homologene: 18573
Mug4-ps
Name: murinoglobulin 4, pseudogene
Synonyms: EG434083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434083
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 170,212,237 bp
  • G to T, chromosome 2 at 28,032,621 bp
  • A to C, chromosome 2 at 38,729,497 bp
  • A to T, chromosome 2 at 53,130,445 bp
  • A to T, chromosome 2 at 66,236,354 bp
  • A to G, chromosome 2 at 71,834,007 bp
  • G to A, chromosome 2 at 76,749,329 bp
  • A to G, chromosome 2 at 86,356,358 bp
  • A to T, chromosome 2 at 110,270,077 bp
  • A to G, chromosome 2 at 130,421,919 bp
  • T to C, chromosome 2 at 162,268,029 bp
  • A to T, chromosome 3 at 101,018,643 bp
  • A to T, chromosome 3 at 116,878,431 bp
  • T to C, chromosome 4 at 150,101,598 bp
  • A to T, chromosome 5 at 64,925,286 bp
  • C to T, chromosome 5 at 76,624,723 bp
  • C to T, chromosome 5 at 114,131,377 bp
  • T to C, chromosome 5 at 115,435,476 bp
  • C to T, chromosome 5 at 136,059,820 bp
  • T to C, chromosome 6 at 67,272,867 bp
  • T to A, chromosome 6 at 97,247,301 bp
  • C to T, chromosome 6 at 121,040,517 bp
  • A to T, chromosome 6 at 121,950,317 bp
  • T to C, chromosome 7 at 16,673,289 bp
  • A to G, chromosome 7 at 18,652,345 bp
  • G to A, chromosome 7 at 25,343,720 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • C to A, chromosome 7 at 104,769,143 bp
  • T to C, chromosome 8 at 9,971,585 bp
  • TCGACG to TCG, chromosome 8 at 71,890,708 bp
  • T to C, chromosome 8 at 84,093,018 bp
  • T to A, chromosome 9 at 8,656,730 bp
  • A to G, chromosome 9 at 15,090,564 bp
  • C to T, chromosome 9 at 44,298,872 bp
  • T to C, chromosome 9 at 123,810,008 bp
  • T to A, chromosome 10 at 22,370,950 bp
  • C to A, chromosome 10 at 87,583,561 bp
  • C to T, chromosome 10 at 130,386,245 bp
  • G to A, chromosome 11 at 33,645,600 bp
  • C to T, chromosome 11 at 58,529,264 bp
  • T to C, chromosome 11 at 95,068,891 bp
  • A to G, chromosome 12 at 101,412,568 bp
  • G to A, chromosome 13 at 67,540,804 bp
  • T to C, chromosome 13 at 74,356,921 bp
  • A to G, chromosome 14 at 51,255,674 bp
  • A to T, chromosome 15 at 92,757,681 bp
  • C to T, chromosome 15 at 102,108,934 bp
  • A to T, chromosome 17 at 12,714,951 bp
  • T to A, chromosome 17 at 20,228,496 bp
  • A to T, chromosome 17 at 27,767,986 bp
  • T to A, chromosome 17 at 33,601,070 bp
  • T to A, chromosome 18 at 10,706,032 bp
  • C to T, chromosome 18 at 60,546,793 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6210 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044344-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.