Strain Name:
C57BL/6J-MtgxR6217Btlr
Stock Number:
044350-MU
Citation ID:
RRID:MMRRC_044350-MU
Other Names:
R6217 (G1)
Major Collection:

Gene Information

Adamts20
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Synonyms: ADAMTS-20, bt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223838
Homologene: 11808
Gon4l
Name: gon-4-like (C.elegans)
Synonyms: 1500041I23Rik, 2610100B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76022
Homologene: 13002
Prtg
Name: protogenin
Synonyms: A230098A12Rik, Igdcc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235472
Homologene: 54453
Sf3b1
Name: splicing factor 3b, subunit 1
Synonyms: SAP155, Prp10, SF3b155, 2810001M05Rik, Targ4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 81898
Homologene: 6696
Usp19
Name: ubiquitin specific peptidase 19
Synonyms: 8430421I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71472
Homologene: 41730
Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Synonyms: 1200015F06Rik, Mypt1, D10Ertd625e, 5730577I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17931
VEGA: 10
HGNC: HGNC:7618
Homologene: 1855
Gab1
Name: growth factor receptor bound protein 2-associated protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14388
HGNC: HGNC:4066
Homologene: 1542
Tmem161b
Name: transmembrane protein 161B
Synonyms: 2810446P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72745
Homologene: 14519
Ubn1
Name: ubinuclein 1
Synonyms: 1110029L11Rik, 2610108L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 170644
VEGA: 16
Homologene: 9656
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: nesprin-1, SYNE-1, enaptin165, A330049M09Rik, C130039F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Bcl7c
Name: B cell CLL/lymphoma 7C
Synonyms: C230096E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12055
HGNC: HGNC:1006
Homologene: 3498
Atp6v1b2
Name: ATPase, H+ transporting, lysosomal V1 subunit B2
Synonyms: HO57, Atp6b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11966
HGNC: HGNC:854
Homologene: 1279
Atp5a1
Name: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Synonyms: Atpm, D18Ertd206e, Mom2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11946
HGNC: HGNC:823
Homologene: 2985
Ticam1
Name: toll-like receptor adaptor molecule 1
Synonyms: TICAM-1, Trif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106759
Homologene: 8605
Ntn1
Name: netrin 1
Synonyms: Netrin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18208
HGNC: HGNC:8029
Homologene: 21008
Rex2
Name: reduced expression 2
Synonyms: Gm13138
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100043034
Homologene: 133076
AU021092
Name: expressed sequence AU021092
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239691
Homologene: 17587
Muc16
Name: mucin 16
Synonyms: LOC385009, 1110008I14Rik, Gm21044
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73732
Homologene: 141193
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Cdc7
Name: cell division cycle 7 (S. cerevisiae)
Synonyms: Cdc7, muCdc7, Cdc7l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12545
HGNC: HGNC:1745
Homologene: 31166
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Exosc10
Name: exosome component 10
Synonyms: PM/Scl-100, PM-Scl, RRP6, p4, p3, p2, Pmscl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50912
HGNC: HGNC:9138
Homologene: 31105
Zfyve27
Name: zinc finger, FYVE domain containing 27
Synonyms: 9530077C24Rik, 2210011N02Rik, protrudin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319740
Homologene: 16939
Ltbr
Name: lymphotoxin B receptor
Synonyms: TNFRrp, TNF receptor-related protein, LT-beta receptor, LT beta-R, Tnfbr, Ltar, TNF-R-III, TNFCR, TNFR2-RP, LTbetaR, Tnfrsf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17000
HGNC: HGNC:6718
Homologene: 1753
Pkd2l2
Name: polycystic kidney disease 2-like 2
Synonyms: Polycystin - L2, TRPP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53871
VEGA: 18
HGNC: HGNC:9012
Homologene: 22812
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212124
Cutc
Name: cutC copper transporter
Synonyms: CGI-32, 2310039I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66388
Homologene: 9318
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Mi-2 alpha, Prp9-1, Prp7, 2600010P09Rik, Chd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Zscan20
Name: zinc finger and SCAN domains 20
Synonyms: Zfp31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269585
Homologene: 51463
Ddhd1
Name: DDHD domain containing 1
Synonyms: 9630061G18Rik, 4921528E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 114874
Homologene: 35221
1700074P13Rik
Name: RIKEN cDNA 1700074P13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73481
Homologene: 49905
Fam160b2
Name: family with sequence similarity 160, member B2
Synonyms: G430067P06Rik, Rai16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239170
VEGA: 14
Homologene: 23379
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546981
Homologene: 115466
Ptprn
Name: protein tyrosine phosphatase, receptor type, N
Synonyms: IA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19275
HGNC: HGNC:9676
Homologene: 48142
Ccdc146
Name: coiled-coil domain containing 146
Synonyms: 4930528G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75172
Homologene: 67159
Cacna1i
Name: calcium channel, voltage-dependent, alpha 1I subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239556
HGNC: HGNC:1396
Homologene: 69331
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94229
Homologene: 23340
Cyp2j6
Name: cytochrome P450, family 2, subfamily j, polypeptide 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13110
HGNC: HGNC:2634
Homologene: 68091
Abraxas2
Name: BRISC complex subunit
Synonyms: C430003P19Rik, KIAA0157, Fam175b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 109359
Homologene: 12970
Dstyk
Name: dual serine/threonine and tyrosine protein kinase
Synonyms: A930019K20Rik, C430014H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213452
Homologene: 19711
Gabrr1
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
Synonyms: GABA-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14408
HGNC: HGNC:4090
Homologene: 20470
Ankdd1a
Name: ankyrin repeat and death domain containing 1A
Synonyms: LOC384945, EG330963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330963
VEGA: 9
Homologene: 65619
Osmr
Name: oncostatin M receptor
Synonyms: OSMRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18414
HGNC: HGNC:8507
Homologene: 2972
Fbxo11
Name: F-box protein 11
Synonyms: GENA 104, Jf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225055
Homologene: 11843
Arsk
Name: arylsulfatase K
Synonyms: 4833414G15Rik, 2810429K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 77041
Homologene: 12670
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224576
Homologene: 135824
Olfr700
Name: olfactory receptor 700
Synonyms: GA_x6K02T2PBJ9-9184187-9183237, MOR283-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258593
Homologene: 64895
Slc17a9
Name: solute carrier family 17, member 9
Synonyms: 1700019H03Rik, Vnut
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228993
Homologene: 76562
Olfr181
Name: olfactory receptor 181
Synonyms: GA_x54KRFPKG5P-55145984-55145034, MOR184-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259001
Homologene: 74112
Lrrc3
Name: leucine rich repeat containing 3
Synonyms: 1300011L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237387
Homologene: 12789
Fancg
Name: Fanconi anemia, complementation group G
Synonyms: Xrcc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 60534
HGNC: HGNC:3588
Homologene: 3402
Lsamp
Name: limbic system-associated membrane protein
Synonyms: Lamp, Lam, B130007O04Rik, D930023J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268890
HGNC: HGNC:6705
Homologene: 20533
Fcmr
Name: Fc fragment of IgM receptor
Synonyms: 1810037B05Rik, FcmuR, Faim3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69169
Homologene: 48347
Ech1
Name: enoyl coenzyme A hydratase 1, peroxisomal
Synonyms: dienoyl-CoA isomerase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 51798
HGNC: HGNC:3149
Homologene: 1069
Asnsd1
Name: asparagine synthetase domain containing 1
Synonyms: 2210409M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70396
Homologene: 6564
Sprr2f
Name: small proline-rich protein 2F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20760
Pcdhgb2
Name: protocadherin gamma subfamily B, 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93700
HGNC: HGNC:8709
Homologene: 49571
Olfr936
Name: olfactory receptor 936
Synonyms: GA_x6K02T2PVTD-32743332-32742397, MOR171-37, EG628171
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100503486
VEGA: 9
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 53,348,028 bp
  • C to T, chromosome 1 at 55,007,518 bp
  • A to T, chromosome 1 at 75,248,166 bp
  • C to T, chromosome 1 at 130,878,323 bp
  • T to C, chromosome 1 at 132,459,939 bp
  • T to G, chromosome 1 at 188,743,454 bp
  • A to G, chromosome 2 at 62,303,951 bp
  • T to A, chromosome 2 at 82,988,418 bp
  • A to G, chromosome 2 at 180,737,662 bp
  • T to C, chromosome 3 at 88,892,661 bp
  • A to T, chromosome 3 at 92,366,059 bp
  • A to T, chromosome 4 at 33,149,026 bp
  • A to C, chromosome 4 at 43,010,084 bp
  • A to G, chromosome 4 at 96,518,161 bp
  • A to T, chromosome 4 at 128,604,534 bp
  • A to G, chromosome 4 at 137,540,248 bp
  • A to G, chromosome 4 at 147,057,474 bp
  • A to G, chromosome 4 at 148,582,311 bp
  • A to T, chromosome 5 at 21,317,902 bp
  • A to G, chromosome 5 at 106,972,794 bp
  • G to A, chromosome 6 at 40,926,085 bp
  • C to T, chromosome 6 at 125,307,454 bp
  • A to G, chromosome 7 at 28,831,836 bp
  • A to T, chromosome 7 at 86,166,167 bp
  • A to T, chromosome 7 at 106,806,072 bp
  • A to T, chromosome 7 at 127,708,526 bp
  • G to A, chromosome 7 at 132,874,965 bp
  • CCTTCTTCT to CCTTCT, chromosome 7 at 139,638,900 bp
  • A to T, chromosome 8 at 48,293,665 bp
  • A to C, chromosome 8 at 69,109,878 bp
  • A to G, chromosome 8 at 80,791,608 bp
  • A to T, chromosome 9 at 18,655,446 bp
  • A to T, chromosome 9 at 39,046,743 bp
  • C to T, chromosome 9 at 65,508,061 bp
  • C to T, chromosome 9 at 72,904,794 bp
  • G to A, chromosome 9 at 108,500,144 bp
  • C to T, chromosome 10 at 5,293,761 bp
  • T to A, chromosome 10 at 77,901,009 bp
  • G to A, chromosome 10 at 108,240,184 bp
  • C to A, chromosome 11 at 68,213,332 bp
  • T to A, chromosome 11 at 69,345,535 bp
  • T to G, chromosome 13 at 11,834,078 bp
  • T to A, chromosome 13 at 76,091,816 bp
  • A to G, chromosome 13 at 84,251,244 bp
  • T to C, chromosome 14 at 45,619,514 bp
  • T to C, chromosome 14 at 70,591,758 bp
  • T to C, chromosome 15 at 6,823,566 bp
  • T to C, chromosome 15 at 80,389,132 bp
  • T to C, chromosome 15 at 94,338,715 bp
  • A to G, chromosome 16 at 5,077,232 bp
  • T to A, chromosome 16 at 5,212,186 bp
  • A to T, chromosome 16 at 42,134,312 bp
  • T to C, chromosome 16 at 58,926,514 bp
  • T to C, chromosome 17 at 20,268,239 bp
  • A to T, chromosome 17 at 56,270,730 bp
  • A to G, chromosome 17 at 88,008,904 bp
  • A to G, chromosome 18 at 34,414,680 bp
  • T to C, chromosome 18 at 37,690,001 bp
  • T to A, chromosome 18 at 77,781,356 bp
  • T to C, chromosome 19 at 42,189,577 bp
  • T to C, chromosome 19 at 43,759,997 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6217 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044350-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.