Strain Name:
C57BL/6J-MtgxR6266Btlr
Stock Number:
044378-MU
Citation ID:
RRID:MMRRC_044378-MU
Other Names:
R6266 (G1)
Major Collection:

Gene Information

Marchf4
Name: membrane associated ring-CH-type finger 4
Synonyms: March4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381270
Homologene: 66199
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Mtarc2
Name: mitochondrial amidoxime reducing component 2
Synonyms: 2810484M10Rik, Mosc2, Marc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67247
Homologene: 9904
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108829
Homologene: 3129
Tns3
Name: tensin 3
Synonyms: TEM6, F830010I22Rik, Tens1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319939
Homologene: 49713
Efnb2
Name: ephrin B2
Synonyms: Epl5, NLERK-1, LERK-5, ELF-2, Htk-L, Eplg5, Lerk5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13642
HGNC: HGNC:3227
Homologene: 3019
Sacm1l
Name: SAC1 suppressor of actin mutations 1-like (yeast)
Synonyms: Sac1p, SAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83493
VEGA: 9
Homologene: 6320
Ppp2r5d
Name: protein phosphatase 2, regulatory subunit B', delta
Synonyms: TEG-271, Tex271, B'delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21770
VEGA: 17
HGNC: HGNC:9312
Homologene: 37661
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227446
Homologene: 10834
Larp1
Name: La ribonucleoprotein domain family, member 1
Synonyms: Larp, 1810024J12Rik, 3110040D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73158
Homologene: 9089
Prpf40a
Name: pre-mRNA processing factor 40A
Synonyms: FBP11, 2810012K09Rik, Fnbp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56194
Homologene: 6377
Psmb7
Name: proteasome (prosome, macropain) subunit, beta type 7
Synonyms: MC14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19177
HGNC: HGNC:9544
Homologene: 2093
Unc13d
Name: unc-13 homolog D
Synonyms: Munc13-4, 2610108D09Rik, Jinx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70450
Homologene: 26714
Slc12a3
Name: solute carrier family 12, member 3
Synonyms: NCC, TSC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20497
Homologene: 287
Brap
Name: BRCA1 associated protein
Synonyms: 3010002G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72399
HGNC: HGNC:1099
Homologene: 4926
Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
Synonyms: MRCKgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240505
Homologene: 28384
Tefm
Name: transcription elongation factor, mitochondrial
Synonyms: FLJ22729, 1110002N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68550
Homologene: 11657
Ccser2
Name: coiled-coil serine rich 2
Synonyms: 1700012P13Rik, 2900054P12Rik, Gcap14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72972
Homologene: 10367
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: 2810409N01Rik, 2610101O16Rik, Gtl4, cat eye syndrome chromosome region, candidate 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Ddx3y
Name: DEAD box helicase 3, Y-linked
Synonyms: Dby, 8030469F12Rik, D1Pas1-rs1, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 26900
HGNC: HGNC:2699
Homologene: 55839
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: P44.5, S9, 1810019E17Rik, C78232, 2810055C24Rik, 2610024G20Rik, 1700089D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Terf2ip
Name: telomeric repeat binding factor 2, interacting protein
Synonyms: Rap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 57321
Homologene: 10357
Tmem231
Name: transmembrane protein 231
Synonyms: 4932417I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234740
Homologene: 78035
Nr1h2
Name: nuclear receptor subfamily 1, group H, member 2
Synonyms: RIP15, LXRbeta, LXRB, Unr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22260
HGNC: HGNC:7965
Homologene: 21397
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Irbp, Rbp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1154Clo, b2b1134Clo, b2b1537Clo, b2b1565Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: DRAG1, E030006K04Rik, Centd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106952
VEGA: 18
Homologene: 11199
Sntg1
Name: syntrophin, gamma 1
Synonyms: G1SYN, SYN4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71096
Homologene: 56834
Lrrc43
Name: leucine rich repeat containing 43
Synonyms: LOC381741
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381741
Homologene: 17662
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231915
Homologene: 4235
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: PBP, Moca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Gm7298
Name: predicted gene 7298
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 640530
Slc20a1
Name: solute carrier family 20, member 1
Synonyms: Glvr-1, Glvr1, PiT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20515
Homologene: 38049
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224572
Homologene: 115024
Dpy19l1
Name: dpy-19-like 1 (C. elegans)
Synonyms: 1100001I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244745
Homologene: 14762
Trp63
Name: transformation related protein 63
Synonyms: KET protein, p63, p73L, Trp53rp1, TAp63, p51/p63, deltaNp63
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22061
Homologene: 31189
Tmx3
Name: thioredoxin-related transmembrane protein 3
Synonyms: 6430411B10Rik, A730024F05Rik, Txndc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67988
VEGA: 18
Homologene: 10381
Zkscan7
Name: zinc finger with KRAB and SCAN domains 7
Synonyms: Zfp167
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382118
VEGA: 9
Homologene: 83284
Fbxl12
Name: F-box and leucine-rich repeat protein 12
Synonyms: 3110048D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 30843
Homologene: 32198
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Fmn1
Name: formin 1
Synonyms: Fmn, formin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14260
HGNC: HGNC:3768
Homologene: 121778
D7Ertd443e
Name: DNA segment, Chr 7, ERATO Doi 443, expressed
Synonyms: 4933400E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71007
Homologene: 18998
Olfr138
Name: olfactory receptor 138
Synonyms: Olfr89, GA_x6K02T2PSCP-2718585-2719523, MOR256-40P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 170648
Homologene: 119758
H6pd
Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms: Gpd-1, Gpd1, G6pd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100198
HGNC: HGNC:4795
Homologene: 48275
Lilra5
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
Synonyms: Gm4878
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232801
Homologene: 83297
Usp36
Name: ubiquitin specific peptidase 36
Synonyms: 2700002L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72344
Homologene: 11828
Hyal2
Name: hyaluronoglucosaminidase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15587
HGNC: HGNC:5321
Homologene: 7776
Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Synonyms: Ahd5, Ahd-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11669
HGNC: HGNC:404
Homologene: 55480
Olfr1123
Name: olfactory receptor 1123
Synonyms: GA_x6K02T2Q125-48917235-48918206, MOR264-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258347
Homologene: 105187
Rrp8
Name: ribosomal RNA processing 8
Synonyms: 2900001K19Rik, 1500003O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101867
Homologene: 5621
Zfp128
Name: zinc finger protein 128
Synonyms: mZnf8, 9630016P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243833
Homologene: 10889
1700014D04Rik
Name: RIKEN cDNA 1700014D04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 102638268
Homologene: 140986
Akr1c12
Name: aldo-keto reductase family 1, member C12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 622402
Homologene: 121208
Tsen34
Name: tRNA splicing endonuclease subunit 34
Synonyms: 0610027F08Rik, Leng5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66078
Homologene: 44182
Efcab8
Name: EF-hand calcium binding domain 8
Synonyms: EG329541
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100504221
Aurkaip1
Name: aurora kinase A interacting protein 1
Synonyms: AIP, Aurora-A kinase interacting protein, 0610033H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66077
Homologene: 11916
Frmpd2
Name: FERM and PDZ domain containing 2
Synonyms: LOC268729, LOC380890, Frmpd2, ENSMUSG00000071536, Gm626
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268729
Homologene: 51854
Trav13d-1
Name: T cell receptor alpha variable 13D-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 640931
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 8,554,729 bp
  • T to C, chromosome 1 at 72,452,488 bp
  • T to G, chromosome 1 at 105,731,282 bp
  • T to C, chromosome 1 at 184,833,943 bp
  • T to C, chromosome 2 at 38,640,187 bp
  • A to T, chromosome 2 at 53,156,627 bp
  • T to A, chromosome 2 at 87,419,006 bp
  • T to A, chromosome 2 at 113,596,338 bp
  • T to C, chromosome 2 at 129,209,894 bp
  • T to C, chromosome 2 at 153,783,768 bp
  • T to C, chromosome 4 at 149,995,957 bp
  • T to G, chromosome 4 at 155,832,520 bp
  • C to A, chromosome 5 at 121,568,934 bp
  • A to T, chromosome 5 at 121,685,265 bp
  • T to C, chromosome 5 at 123,503,277 bp
  • T to A, chromosome 5 at 149,204,366 bp
  • A to G, chromosome 6 at 120,761,686 bp
  • A to T, chromosome 6 at 121,782,704 bp
  • A to G, chromosome 7 at 3,693,985 bp
  • T to A, chromosome 7 at 4,241,928 bp
  • T to C, chromosome 7 at 12,890,970 bp
  • A to T, chromosome 7 at 44,552,052 bp
  • C to A, chromosome 7 at 80,499,940 bp
  • T to C, chromosome 7 at 105,736,389 bp
  • A to T, chromosome 7 at 134,349,785 bp
  • T to C, chromosome 8 at 8,660,524 bp
  • A to G, chromosome 8 at 94,358,471 bp
  • T to A, chromosome 8 at 111,915,265 bp
  • T to A, chromosome 8 at 112,011,915 bp
  • A to T, chromosome 9 at 20,638,615 bp
  • A to G, chromosome 9 at 24,439,146 bp
  • T to A, chromosome 9 at 106,964,753 bp
  • A to G, chromosome 9 at 107,570,715 bp
  • C to T, chromosome 9 at 122,895,234 bp
  • T to C, chromosome 9 at 123,542,420 bp
  • C to T, chromosome 10 at 67,249,660 bp
  • G to A, chromosome 11 at 8,492,987 bp
  • A to G, chromosome 11 at 58,042,263 bp
  • A to G, chromosome 11 at 80,137,988 bp
  • A to G, chromosome 11 at 80,445,941 bp
  • A to G, chromosome 11 at 116,068,238 bp
  • A to G, chromosome 11 at 118,268,585 bp
  • T to C, chromosome 13 at 4,270,207 bp
  • C to T, chromosome 13 at 59,742,312 bp
  • T to C, chromosome 14 at 33,565,907 bp
  • G to A, chromosome 14 at 33,954,461 bp
  • G to A, chromosome 14 at 36,879,675 bp
  • T to A, chromosome 14 at 52,851,763 bp
  • T to A, chromosome 15 at 28,335,627 bp
  • A to G, chromosome 16 at 25,862,460 bp
  • T to A, chromosome 17 at 19,678,745 bp
  • A to G, chromosome 17 at 38,275,148 bp
  • G to T, chromosome 17 at 46,685,703 bp
  • G to A, chromosome 18 at 37,990,791 bp
  • T to A, chromosome 18 at 90,537,210 bp
  • A to G, chromosome 19 at 6,311,473 bp
  • T to C, chromosome 19 at 6,398,139 bp
  • G to A, chromosome Y at 1,266,635 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6266 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044378-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.