Strain Name:
C57BL/6J-MtgxR6304Btlr
Stock Number:
044380-MU
Citation ID:
RRID:MMRRC_044380-MU
Other Names:
R6304 (G1)
Major Collection:

Gene Information

Nrp2
Name: neuropilin 2
Synonyms: Npn2, 1110048P06Rik, NP-2, NP2, Npn-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18187
HGNC: HGNC:8005
Homologene: 2875
Pomt1
Name: protein-O-mannosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99011
HGNC: HGNC:9202
Homologene: 68548
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Etaa1
Name: Ewing tumor-associated antigen 1
Synonyms: 5730466H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68145
Homologene: 10369
Kdm2b
Name: lysine (K)-specific demethylase 2B
Synonyms: Fbxl10, Jhdm1b, Cxxc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 30841
Homologene: 13069
Plcg1
Name: phospholipase C, gamma 1
Synonyms: Cded, Plc-1, Plc-gamma1, Plcg-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18803
HGNC: HGNC:9065
Homologene: 1997
Sh3gl1
Name: SH3-domain GRB2-like 1
Synonyms: SH3P8, endophilin II, Sh3d2b, EEN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20405
VEGA: 17
Homologene: 55709
Phyhipl
Name: phytanoyl-CoA hydroxylase interacting protein-like
Synonyms: 4921522K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70911
Homologene: 13028
Lpar1
Name: lysophosphatidic acid receptor 1
Synonyms: LPA1, vzg-1, Kdt2, Gpcr26, Edg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14745
HGNC: HGNC:3166
Homologene: 1072
Robo2
Name: roundabout guidance receptor 2
Synonyms: 2600013A04Rik, 9430089E08Rik, D230004I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268902
Homologene: 43188
Elapor1
Name: endosome-lysosome associated apoptosis and autophagy regulator 1
Synonyms: 5330417C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229722
Homologene: 23249
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: 4930429G18Rik, C030002J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78787
Homologene: 90902
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: 105kDa, 4932409F03Rik, 2610524B04Rik, Taf2c2, TAFII105
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 72504
VEGA: 18
Homologene: 28266
Kdm6b
Name: KDM1 lysine (K)-specific demethylase 6B
Synonyms: Jmjd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216850
Homologene: 18945
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100604
Homologene: 12997
Soga1
Name: suppressor of glucose, autophagy associated 1
Synonyms: D430036N24Rik, 9830001H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320706
Homologene: 52382
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Ttn
Name: titin
Synonyms: D830007G01Rik, connectin, 1100001C23Rik, 2310036G12Rik, mdm, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru, L56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Lgn1, Naip-rs3, Birc1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Olfr639
Name: olfactory receptor 639
Synonyms: GA_x6K02T2PBJ9-6747143-6746193, MOR12-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259088
Homologene: 17497
Trim14
Name: tripartite motif-containing 14
Synonyms: 5830400N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74735
Homologene: 13241
Cped1
Name: cadherin-like and PC-esterase domain containing 1
Synonyms: A430107O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 214642
Homologene: 57014
Gramd4
Name: GRAM domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223752
Homologene: 18199
Dnai4
Name: dynein axonemal intermediate chain 4
Synonyms: Wdr78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242584
Homologene: 11702
Lingo4
Name: leucine rich repeat and Ig domain containing 4
Synonyms: LERN4, A530050P17Rik, Lrrn6d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320747
Homologene: 18563
4932415D10Rik
Name: RIKEN cDNA 4932415D10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086, AI414108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235086
Homologene: 19472
Kcnh7
Name: potassium voltage-gated channel, subfamily H (eag-related), member 7
Synonyms: Kv11.3, 9330137I11Rik, erg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170738
Homologene: 13249
Pcdhb9
Name: protocadherin beta 9
Synonyms: Pcdhb4C, PcdhbI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93880
Homologene: 87124
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 28010
Homologene: 15879
Spsb1
Name: splA/ryanodine receptor domain and SOCS box containing 1
Synonyms: SSB1, 1110014L01Rik, 4930422J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74646
Homologene: 11832
Osbpl3
Name: oxysterol binding protein-like 3
Synonyms: 6720421I08Rik, 1200014M06Rik, ORP3, OSBP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71720
Homologene: 49422
Cbll1
Name: Casitas B-lineage lymphoma-like 1
Synonyms: c-Cbl-like, Hakai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104836
Homologene: 11734
Kcnh3
Name: potassium voltage-gated channel, subfamily H (eag-related), member 3
Synonyms: C030044P22Rik, Elk2, ether a go-go like, Melk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16512
VEGA: 15
HGNC: HGNC:6252
Homologene: 32150
Bin3
Name: bridging integrator 3
Synonyms: 1700015F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57784
VEGA: 14
HGNC: HGNC:1054
Homologene: 5472
Pcdhb6
Name: protocadherin beta 6
Synonyms: PcdhbF, Pcdhb5B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93877
Homologene: 62177
Sesn3
Name: sestrin 3
Synonyms: 5630400E15Rik, SEST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75747
Homologene: 14386
Vmn2r51
Name: vomeronasal 2, receptor 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100042921
Homologene: 113703
Vmn1r3
Name: vomeronasal 1 receptor 3
Synonyms: Gm11778
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100312471
Homologene: 128342
Mup4
Name: major urinary protein 4
Synonyms: Mup-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17843
Homologene: 74304
G6pc
Name: glucose-6-phosphatase, catalytic
Synonyms: G6Pase, G6pt, Glc-6-Pase, Glc-6-Pase-alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14377
HGNC: HGNC:4056
Homologene: 20079
Ifna5
Name: interferon alpha 5
Synonyms: Ifa5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15968
HGNC: HGNC:5425
Homologene: 68536
Apol9b
Name: apolipoprotein L 9b
Synonyms: 2310016F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71898
VEGA: 15
Homologene: 77567
Lrrc10b
Name: leucine rich repeat containing 10B
Synonyms: LOC278795, Gm705, SerdinR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 278795
VEGA: 19
Homologene: 19583
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 62,745,406 bp
  • T to A, chromosome 2 at 32,250,790 bp
  • A to T, chromosome 2 at 62,764,616 bp
  • A to T, chromosome 2 at 76,891,099 bp
  • G to T, chromosome 2 at 76,915,735 bp
  • T to C, chromosome 2 at 157,040,764 bp
  • A to G, chromosome 2 at 160,761,463 bp
  • G to A, chromosome 3 at 94,403,206 bp
  • A to C, chromosome 3 at 108,461,256 bp
  • T to A, chromosome 4 at 3,184,975 bp
  • C to A, chromosome 4 at 46,522,118 bp
  • T to C, chromosome 4 at 58,487,013 bp
  • T to C, chromosome 4 at 59,960,084 bp
  • T to C, chromosome 4 at 88,835,910 bp
  • T to C, chromosome 4 at 103,087,356 bp
  • T to C, chromosome 4 at 147,863,083 bp
  • C to T, chromosome 4 at 149,906,731 bp
  • A to T, chromosome 5 at 14,677,893 bp
  • A to T, chromosome 5 at 105,608,609 bp
  • A to G, chromosome 5 at 122,881,744 bp
  • A to T, chromosome 6 at 22,016,923 bp
  • A to G, chromosome 6 at 50,312,674 bp
  • T to C, chromosome 7 at 10,098,237 bp
  • G to A, chromosome 7 at 104,012,031 bp
  • A to T, chromosome 8 at 16,058,674 bp
  • A to T, chromosome 9 at 14,322,561 bp
  • C to T, chromosome 9 at 27,342,575 bp
  • A to G, chromosome 10 at 70,559,557 bp
  • T to A, chromosome 10 at 82,290,368 bp
  • A to C, chromosome 11 at 17,947,505 bp
  • G to T, chromosome 11 at 69,404,258 bp
  • A to G, chromosome 11 at 101,367,909 bp
  • A to G, chromosome 12 at 31,494,589 bp
  • C to T, chromosome 13 at 100,223,166 bp
  • T to C, chromosome 14 at 20,560,968 bp
  • A to G, chromosome 14 at 70,137,176 bp
  • T to C, chromosome 15 at 8,118,042 bp
  • T to A, chromosome 15 at 77,735,304 bp
  • A to G, chromosome 15 at 86,134,919 bp
  • T to C, chromosome 15 at 99,227,038 bp
  • T to A, chromosome 16 at 73,958,308 bp
  • A to T, chromosome 17 at 56,036,431 bp
  • T to C, chromosome 18 at 14,807,355 bp
  • C to T, chromosome 18 at 37,335,921 bp
  • T to A, chromosome 18 at 37,401,367 bp
  • T to C, chromosome 19 at 10,456,978 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6304 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044380-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.