Strain Name:
C57BL/6J-MtgxR6372Btlr/Mmmh
Stock Number:
044522-MU
Citation ID:
RRID:MMRRC_044522-MU
Other Names:
R6372 (G1)
Major Collection:

Strain Information

Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: Tkr, TrkA
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Ncoa3
Name: nuclear receptor coactivator 3
Synonyms: AIB1, TRAM-1, TRAM1, pCIP, bHLHe42, Src3, KAT13B, 2010305B15Rik, RAC3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17979
HGNC: HGNC:7670
Homologene: 4764
Elovl6
Name: ELOVL fatty acid elongase 6
Synonyms: ELOVL family member 6, elongation of long chain fatty acids (yeast), LCE, FEN1/Elo2, SUR4/Elo3-like
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170439
Homologene: 11456
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 4632408O18Rik, TRS130, Nibp, 1810044A24Rik, 2900005P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Nol9
Name: nucleolar protein 9
Synonyms: 6030462G04Rik, 4632412I24Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74035
Homologene: 32589
Ubn1
Name: ubinuclein 1
Synonyms: 1110029L11Rik, 2610108L02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 170644
VEGA: 16
Homologene: 9656
Usf2
Name: upstream transcription factor 2
Synonyms: Usf-2, bHLHb12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22282
Homologene: 2527
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC385637, LOC224088, LOC224087
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224088
Homologene: 23455
Gm2381
Name: predicted gene 2381
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100039706
Nbeal2
Name: neurobeachin-like 2
Synonyms: 1110014F23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235627
Homologene: 86422
Fcrl5
Name: Fc receptor-like 5
Synonyms: BXMAS1-like protein 2, Fcrh3, mBXMH2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329693
Homologene: 137404
Hk1
Name: hexokinase 1
Synonyms: Hk-1, Hk1-s, mHk1-s
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Tbc1d19
Name: TBC1 domain family, member 19
Synonyms: 2810453K03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67249
Homologene: 10130
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: 105kDa, 4932409F03Rik, Taf2c2, TAFII105, 2610524B04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72504
VEGA: 18
Homologene: 28266
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142980
Homologene: 20696
Zfp808
Name: zinc finger protein 808
Synonyms: Gm7036
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 630579
Homologene: 134631
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53867
Homologene: 9253
Itga9
Name: integrin alpha 9
Synonyms: 6720458D17Rik, 2610002H11Rik, D9Ertd428e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 104099
HGNC: HGNC:6145
Homologene: 1664
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Rubcnl
Name: RUN and cysteine rich domain containing beclin 1 interacting protein like
Synonyms: LOC380917, 5031414D18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 271221
VEGA: 14
Homologene: 57021
Cryga
Name: crystallin, gamma A
Synonyms: Cryg-4, Secc, DGcry-4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12964
HGNC: HGNC:2408
Homologene: 129704
Nlrc5
Name: NLR family, CARD domain containing 5
Synonyms: AI451557
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 434341
Homologene: 88935
Clec2g
Name: C-type lectin domain family 2, member g
Synonyms: Ocilrp1, 4632413B12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70809
Homologene: 136309
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Nol4
Name: nucleolar protein 4
Synonyms: 4930568N03Rik, LOC383304, 1700013J13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319211
HGNC: HGNC:7870
Homologene: 36142
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Or8h8
Name: olfactory receptor family 8 subfamily H member 8
Synonyms: MOR206-1, Olfr1098, GA_x6K02T2Q125-48410458-48409511
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258842
Homologene: 37005
Tecpr1
Name: tectonin beta-propeller repeat containing 1
Synonyms: 2210010N04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70381
Homologene: 9120
Atxn1
Name: ataxin 1
Synonyms: Atx1, Sca1, 2900016G23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20238
VEGA: 13
Homologene: 281
Pcdhb19
Name: protocadherin beta 19
Synonyms: PcdhbS, Pcdhb11
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93890
Homologene: 128411
Rhbdl3
Name: rhomboid like 3
Synonyms: Rhbdl4, Ventrhoid, Vrho
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246104
Homologene: 34700
Or5d16
Name: olfactory receptor family 5 subfamily D member 16
Synonyms: GA_x6K02T2Q125-49426894-49425950, Olfr1155, MOR174-10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258636
Homologene: 133739
Aim2
Name: absent in melanoma 2
Synonyms: LOC383619, Ifi210
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 383619
HGNC: HGNC:357
Homologene: 83226
1700113H08Rik
Name: RIKEN cDNA 1700113H08 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76640
Homologene: 45695
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Megf11
Name: multiple EGF-like-domains 11
Synonyms: 2410080H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214058
Homologene: 13031
Tnk2
Name: tyrosine kinase, non-receptor, 2
Synonyms: ACK1, activated p21cdc42Hs kinase, Pyk1, P21cdc42Hs kinase, Ack
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 51789
Homologene: 4224
Mrpl45
Name: mitochondrial ribosomal protein L45
Synonyms: 2600005P05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67036
Homologene: 32647
Vmn2r65
Name: vomeronasal 2, receptor 65
Synonyms: ENSMUSG00000070600
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100009609
Recql
Name: RecQ protein-like
Synonyms: RecQ1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19691
HGNC: HGNC:9948
Homologene: 56279
Pbx4
Name: pre B cell leukemia homeobox 4
Synonyms: 2410015M21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 80720
Homologene: 57027
Zeb2
Name: zinc finger E-box binding homeobox 2
Synonyms: D130016B08Rik, SIP1, Zfx1b, 9130203F04Rik, Zfhx1b
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24136
Homologene: 8868
Or2y11
Name: olfactory receptor family 2 subfamily Y member 11
Synonyms: GA_x6K02T2QP88-5884501-5883566, Olfr1381, MOR256-26
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258461
Homologene: 72463
Gimap1
Name: GTPase, IMAP family member 1
Synonyms: Imap38, IAP38, 38kDa, imap
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16205
Homologene: 7379
Vxn
Name: vexin
Synonyms: R75066, 3110035E14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76982
Homologene: 17666
Ccdc183
Name: coiled-coil domain containing 183
Synonyms: Cccd183, 4921530D09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77058
Homologene: 50023
Or4k40
Name: olfactory receptor family 4 subfamily K member 40
Synonyms: GA_x6K02T2Q125-72472405-72471488, MOR248-21, Olfr1286
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277562
Homologene: 73992
Or5al5
Name: olfactory receptor family 5 subfamily AL member 5
Synonyms: MOR185-5, MOR185-5, GA_x6K02T2Q125-47600809-47599850, MOR185-9P, Olfr1039, Olfr1517, MOR185-5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257950
Homologene: 79382
Gnl1
Name: guanine nucleotide binding protein-like 1
Synonyms: Gna-rs1, Gnal1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14670
HGNC: HGNC:4413
Homologene: 3862
Tpmt
Name: thiopurine methyltransferase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 22017
Homologene: 313
Cacnb4
Name: calcium channel, voltage-dependent, beta 4 subunit
Synonyms: 3110038O15Rik, Cchb4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12298
HGNC: HGNC:1404
Homologene: 20188
Slc26a8
Name: solute carrier family 26, member 8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224661
Homologene: 27095
Pde2a
Name: phosphodiesterase 2A, cGMP-stimulated
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207728
HGNC: HGNC:8777
Homologene: 1952
Dnajc28
Name: DnaJ heat shock protein family (Hsp40) member C28
Synonyms: ORF28
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 246738
HGNC: HGNC:1297
Homologene: 9869
Rtkn
Name: rhotekin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20166
Homologene: 7522
Vmn1r57
Name: vomeronasal 1 receptor 57
Synonyms: Gm7519
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 665150
Homologene: 41799
Ighv7-2
Name: immunoglobulin heavy variable 7-2
Synonyms: Gm16699
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780800
HGNC: HGNC:5633
Gm17472
Name: predicted gene, 17472
Type: Gene
Species: Mouse
Chromosome: 6
Psmb5
Name: proteasome (prosome, macropain) subunit, beta type 5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19173
VEGA: 14
HGNC: HGNC:9542
Homologene: 55690
Trav13-4-dv7
Name: T cell receptor alpha variable 13-4-DV7
Synonyms: Gm13934
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100113412
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 9,613,321 bp
  • T to C, chromosome 1 at 65,103,045 bp
  • T to A, chromosome 1 at 173,455,236 bp
  • T to C, chromosome 2 at 25,616,164 bp
  • T to C, chromosome 2 at 45,002,539 bp
  • T to A, chromosome 2 at 52,434,667 bp
  • T to C, chromosome 2 at 86,130,854 bp
  • T to A, chromosome 2 at 86,923,155 bp
  • T to C, chromosome 2 at 87,942,975 bp
  • T to A, chromosome 2 at 111,420,802 bp
  • C to T, chromosome 2 at 166,059,347 bp
  • C to T, chromosome 2 at 181,233,467 bp
  • C to T, chromosome 3 at 87,444,194 bp
  • T to C, chromosome 3 at 87,786,048 bp
  • T to C, chromosome 3 at 129,633,102 bp
  • T to C, chromosome 4 at 152,045,995 bp
  • T to G, chromosome 5 at 53,856,910 bp
  • C to T, chromosome 5 at 144,216,958 bp
  • T to C, chromosome 6 at 42,980,889 bp
  • A to T, chromosome 6 at 48,472,541 bp
  • T to A, chromosome 6 at 48,743,356 bp
  • A to G, chromosome 6 at 83,151,901 bp
  • A to C, chromosome 6 at 128,948,763 bp
  • A to G, chromosome 6 at 142,376,840 bp
  • T to C, chromosome 7 at 5,220,827 bp
  • A to G, chromosome 7 at 28,107,008 bp
  • G to A, chromosome 7 at 30,955,313 bp
  • G to A, chromosome 7 at 42,820,586 bp
  • G to T, chromosome 7 at 84,940,653 bp
  • G to A, chromosome 7 at 101,481,392 bp
  • A to G, chromosome 8 at 45,397,011 bp
  • C to A, chromosome 8 at 69,872,044 bp
  • T to C, chromosome 8 at 94,479,750 bp
  • A to G, chromosome 9 at 20,785,586 bp
  • T to C, chromosome 9 at 64,706,625 bp
  • T to C, chromosome 9 at 110,628,744 bp
  • A to G, chromosome 9 at 118,897,321 bp
  • C to A, chromosome 10 at 39,067,952 bp
  • T to C, chromosome 10 at 62,291,978 bp
  • T to A, chromosome 10 at 87,230,226 bp
  • A to G, chromosome 11 at 49,551,930 bp
  • C to A, chromosome 11 at 80,330,656 bp
  • T to C, chromosome 11 at 97,321,562 bp
  • G to A, chromosome 12 at 113,912,455 bp
  • T to A, chromosome 13 at 45,557,456 bp
  • C to T, chromosome 13 at 47,035,894 bp
  • T to C, chromosome 13 at 62,172,477 bp
  • T to C, chromosome 14 at 53,757,661 bp
  • C to A, chromosome 14 at 54,616,673 bp
  • C to A, chromosome 14 at 75,047,569 bp
  • T to A, chromosome 15 at 72,590,074 bp
  • C to T, chromosome 16 at 5,081,638 bp
  • T to C, chromosome 16 at 30,343,455 bp
  • T to A, chromosome 16 at 32,679,785 bp
  • T to C, chromosome 16 at 91,617,288 bp
  • T to C, chromosome 17 at 28,644,803 bp
  • T to C, chromosome 17 at 35,982,535 bp
  • T to G, chromosome 18 at 14,804,733 bp
  • A to G, chromosome 18 at 23,038,556 bp
  • T to A, chromosome 18 at 37,497,366 bp
  • T to C, chromosome 19 at 57,650,332 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6372 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044522-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.