Strain Name:
C57BL/6J-MtgxR6652Btlr/Mmmh
Stock Number:
044773-MU
Citation ID:
RRID:MMRRC_044773-MU
Other Names:
R6652 (G1)
Major Collection:

Strain Information

Mc1r
Name: melanocortin 1 receptor
Synonyms: Mshra, Mcr1, extension recessive yellow, e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17199
HGNC: HGNC:6929
Homologene: 1789
Ubap2
Name: ubiquitin-associated protein 2
Synonyms: 1190005K07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68926
Homologene: 73649
Stoml1
Name: stomatin-like 1
Synonyms: UNC-24, WPB72, SLP-1, 1810015E19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69106
VEGA: 9
Homologene: 31265
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 2410152H17Rik, 2900036C23Rik, 2810413I22Rik, 6030449K19Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66315
Homologene: 10778
Fam193b
Name: family with sequence similarity 193, member B
Synonyms: IRIZIO
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212483
VEGA: 13
Homologene: 130095
Ncapd2
Name: non-SMC condensin I complex, subunit D2
Synonyms: 2810465G24Rik, 2810406C15Rik, CNAP1, CAP-D2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68298
Homologene: 6497
Zfp317
Name: zinc finger protein 317
Synonyms: D230022C05Rik, KRAB9, Zfp75, Zfp67
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244713
Homologene: 36389
Dag1
Name: dystroglycan 1
Synonyms: beta-dystroglycan, alpha-dystroglycan, D9Wsu13e, DG, dystrophin associated glycoprotein 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13138
HGNC: HGNC:2666
Homologene: 3234
Stn1
Name: STN1, CST complex subunit
Synonyms: 2310057J23Rik, 0610009H20Rik, Obfc1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 108689
Homologene: 11788
Cwf19l1
Name: CWF19 like cell cycle control factor 1
Synonyms: 2610528C06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72502
VEGA: 19
Homologene: 41244
Sfxn3
Name: sideroflexin 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94280
VEGA: 19
Homologene: 23394
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229474
Homologene: 18920
Mov10l1
Name: Mov10 like RISC complex RNA helicase 1
Synonyms: CHAMP, Csm
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 83456
HGNC: HGNC:7201
Homologene: 56835
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E21Rik, 2310076E16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, Fath2, mKIAA0811, LOC245827
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: C330002I19Rik, 3110039L19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77480
VEGA: 12
Homologene: 14254
Nadsyn1
Name: NAD synthetase 1
Synonyms: 9130012B15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78914
Homologene: 6098
Vmn1r204
Name: vomeronasal 1 receptor 204
Synonyms: Gm11301
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 632793
Homologene: 110880
Clk3
Name: CDC-like kinase 3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102414
VEGA: 9
HGNC: HGNC:2071
Homologene: 101534
Mthfsd
Name: methenyltetrahydrofolate synthetase domain containing
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234814
Homologene: 11245
Abca14
Name: ATP-binding cassette, sub-family A member 14
Synonyms: 4930539G24Rik, 1700110B15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67928
Homologene: 86128
Espnl
Name: espin-like
Synonyms: LOC227357
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227357
Homologene: 77795
Thap2
Name: THAP domain containing, apoptosis associated protein 2
Synonyms: 9030625G08Rik, 2900040O07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66816
VEGA: 10
Homologene: 12039
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226438
Homologene: 130054
Spart
Name: spartin
Synonyms: Spg20, TAHCCP1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229285
Prss37
Name: serine protease 37
Synonyms: 1700016G05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67690
Homologene: 12174
Cfh
Name: complement component factor h
Synonyms: Sas1, Mud-1, Sas-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12628
HGNC: HGNC:4883
Homologene: 20086
Fut9
Name: fucosyltransferase 9
Synonyms: mFUT9, mFuc-TIX
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14348
HGNC: HGNC:4020
Homologene: 4800
Wnt10a
Name: wingless-type MMTV integration site family, member 10A
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22409
Homologene: 22525
Musk
Name: muscle, skeletal, receptor tyrosine kinase
Synonyms: Nsk2, Nsk1, MDK4, Nsk3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18198
HGNC: HGNC:7525
Homologene: 4084
Ergic2
Name: ERGIC and golgi 2
Synonyms: 4930572C01Rik, 1200009B18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67456
Homologene: 6574
Kti12
Name: KTI12 homolog, chromatin associated
Synonyms: 1110001A12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100087
Homologene: 6347
Vezt
Name: vezatin, adherens junctions transmembrane protein
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215008
Homologene: 9739
Or4e5
Name: olfactory receptor family 4 subfamily E member 5
Synonyms: MOR244-1, MOR28, GA_x6K02T2RJGY-491851-492792, Olfr1507
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57269
HGNC: HGNC:8296
Homologene: 10736
Yipf7
Name: Yip1 domain family, member 7
Synonyms: 2310016N21Rik, Yip1b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75581
Homologene: 69367
Zdhhc19
Name: zinc finger, DHHC domain containing 19
Synonyms: LOC245308
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 245308
Homologene: 34922
Sebox
Name: SEBOX homeobox
Synonyms: OG9, Og9x
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18292
Homologene: 32052
Gpt2
Name: glutamic pyruvate transaminase (alanine aminotransferase) 2
Synonyms: 4631422C05Rik, ALT2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 108682
Homologene: 68832
Grap2
Name: GRB2-related adaptor protein 2
Synonyms: Mona, Grf40, P38, GRID, GrpL, Gads, GrbX, GRAP-2, Grb2-related adaptor downstream of Sch, GRB2L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17444
VEGA: 15
HGNC: HGNC:4563
Homologene: 21007
Or6y1
Name: olfactory receptor family 6 subfamily Y member 1
Synonyms: GA_x6K02SYWY4V-595-239, GA_x6K02T2P20D-20731742-20730694, Olfr413-ps1, MOR103-17, Olfr220, MOR103-13P, EG546747
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 546747
Homologene: 67062
Krtap10-27
Name: keratin associated protein 10-27
Synonyms: Gm9507
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 670880
Homologene: 115744
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,803,454 bp
  • A to C, chromosome 1 at 91,344,699 bp
  • A to G, chromosome 1 at 135,963,871 bp
  • A to T, chromosome 1 at 140,144,068 bp
  • G to A, chromosome 1 at 174,449,061 bp
  • G to A, chromosome 3 at 55,124,827 bp
  • T to C, chromosome 3 at 84,464,324 bp
  • G to C, chromosome 4 at 25,620,619 bp
  • A to T, chromosome 4 at 41,196,743 bp
  • C to T, chromosome 4 at 58,368,977 bp
  • T to A, chromosome 4 at 108,848,533 bp
  • A to G, chromosome 5 at 69,541,161 bp
  • C to A, chromosome 6 at 40,519,156 bp
  • G to A, chromosome 6 at 125,186,270 bp
  • T to C, chromosome 6 at 148,189,581 bp
  • A to G, chromosome 7 at 120,246,941 bp
  • A to T, chromosome 7 at 143,811,218 bp
  • G to A, chromosome 8 at 85,518,052 bp
  • A to T, chromosome 8 at 121,098,821 bp
  • G to A, chromosome 8 at 123,407,631 bp
  • C to T, chromosome 9 at 19,647,039 bp
  • A to G, chromosome 9 at 57,761,795 bp
  • A to G, chromosome 9 at 58,256,734 bp
  • A to T, chromosome 9 at 108,209,090 bp
  • A to T, chromosome 10 at 77,811,659 bp
  • A to G, chromosome 10 at 93,970,279 bp
  • T to A, chromosome 10 at 115,376,536 bp
  • T to A, chromosome 11 at 55,252,262 bp
  • A to T, chromosome 11 at 78,503,805 bp
  • T to A, chromosome 12 at 25,010,060 bp
  • T to A, chromosome 12 at 115,920,431 bp
  • T to C, chromosome 13 at 22,556,403 bp
  • A to G, chromosome 13 at 55,542,790 bp
  • A to G, chromosome 13 at 93,092,895 bp
  • T to C, chromosome 13 at 93,093,039 bp
  • C to T, chromosome 14 at 52,490,793 bp
  • A to T, chromosome 15 at 76,179,774 bp
  • A to T, chromosome 15 at 80,648,522 bp
  • A to G, chromosome 15 at 88,993,902 bp
  • T to C, chromosome 16 at 32,497,229 bp
  • C to A, chromosome 16 at 56,123,894 bp
  • T to C, chromosome 19 at 44,114,699 bp
  • G to A, chromosome 19 at 45,049,915 bp
  • T to C, chromosome 19 at 47,507,578 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6652 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044773-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.