Strain Name:
C57BL/6J-MtgxR6695Btlr/Mmmh
Stock Number:
044813-MU
Citation ID:
RRID:MMRRC_044813-MU
Other Names:
R6695 (G1)
Major Collection:

Strain Information

Tnrc6b
Name: trinucleotide repeat containing 6b
Synonyms: A730065C02Rik, D230019K20Rik, 2700090M07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 213988
VEGA: 15
Homologene: 66194
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: T-type Cav3.2, alpha13.2, Cav3.2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Dtx4
Name: deltex 4, E3 ubiquitin ligase
Synonyms: RNF155
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 207521
VEGA: 19
Homologene: 27781
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: 2900024N03Rik, Rnf164, 9430019J22Rik, Mnab, D930043C02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319817
Homologene: 28276
Luzp1
Name: leucine zipper protein 1
Synonyms: 2700072H04Rik, Luzp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269593
Homologene: 11545
Nomo1
Name: nodal modulator 1
Synonyms: Nomo, D7Ertd156e, PM5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211548
Homologene: 13810
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Nav2
Name: neuron navigator 2
Synonyms: Rainb1, POMFIL2, Unc53H2, 5330421F07Rik, HELAD1, RAINB2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78286
Homologene: 52330
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: 2810449H11Rik, D130015N03Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Zbtb17
Name: zinc finger and BTB domain containing 17
Synonyms: Miz1, Zfp100, mZ13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22642
Homologene: 2575
Tonsl
Name: tonsoku-like, DNA repair protein
Synonyms: 2810439M11Rik, Nfkbil2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72749
HGNC: HGNC:7801
Homologene: 22754
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231214
Homologene: 18159
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: Zzank1, 2210008I11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76580
Homologene: 16062
Muc15
Name: mucin 15
Synonyms: D730046L02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269328
Homologene: 51680
Knstrn
Name: kinetochore-localized astrin/SPAG5 binding
Synonyms: 1700025D04Rik, D2Ertd750e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51944
Homologene: 12198
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: 4930429G18Rik, C030002J06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 78787
Homologene: 90902
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hyrh, hy-3, hy3, 1700034M11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna1, ihj, erythroid, Spna-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20739
Homologene: 74460
Swsap1
Name: SWIM type zinc finger 7 associated protein 1
Synonyms: 2310047B19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66962
VEGA: 9
Homologene: 18487
Man2c1
Name: mannosidase, alpha, class 2C, member 1
Synonyms: 1110025H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73744
HGNC: HGNC:6827
Homologene: 4887
Strc
Name: stereocilin
Synonyms: DFNB16
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 140476
Homologene: 15401
Sugct
Name: succinyl-CoA glutarate-CoA transferase
Synonyms: 5033411D12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 192136
VEGA: 13
Homologene: 11681
Rad9b
Name: RAD9 checkpoint clamp component B
Synonyms: A630082N15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231724
Homologene: 17006
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Rab11fip1
Name: RAB11 family interacting protein 1 (class I)
Synonyms: 4833414G05Rik, 2010200K21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75767
Homologene: 11853
Myo1c
Name: myosin IC
Synonyms: mm1beta, C80397, myr2, myosin-Ibeta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
Synonyms: C130026N12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71751
VEGA: 16
HGNC: HGNC:6852
Homologene: 37958
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Dmwd
Name: dystrophia myotonica-containing WD repeat motif
Synonyms: 59, DMR-N9, Dm9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13401
HGNC: HGNC:2936
Homologene: 22559
Mia2
Name: MIA SH3 domain ER export factor 2
Synonyms: Mgea, Ctage5, Mgea6, MEA6, D12Bwg0579e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 338320
Homologene: 137655
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Or5b24
Name: olfactory receptor family 5 subfamily B member 24
Synonyms: Olfr1449, MOR202-34, GA_x6K02T2RE5P-3264213-3265157
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258300
Homologene: 17184
Spdl1
Name: spindle apparatus coiled-coil protein 1
Synonyms: 1700018I02Rik, Ccdc99, 2600001J17Rik, 2810049B11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70385
Homologene: 9837
Ppm1j
Name: protein phosphatase 1J
Synonyms: Ppp2cz, PP2Czeta, 2310008J22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71887
Homologene: 23632
Vps52
Name: VPS52 GARP complex subunit
Synonyms: Sacm2l, tclw5, tcl-w5, D430041K17Rik, ARE1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224705
Homologene: 5756
Or1j10
Name: olfactory receptor family 1 subfamily J member 10
Synonyms: MOR136-5, GA_x6K02T2NLDC-33070879-33071799, Olfr338
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258949
Homologene: 133647
Stk32c
Name: serine/threonine kinase 32C
Synonyms: YANK3, Pkek
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57740
Homologene: 75157
Or5g27
Name: olfactory receptor family 5 subfamily G member 27
Synonyms: GA_x6K02T2Q125-47058060-47059004, MOR175-4, Olfr996
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258429
Homologene: 85934
Plk5
Name: polo like kinase 5
Synonyms: 6330514A18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216166
Homologene: 28072
Galntl6
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
Synonyms: 4930431L04Rik, 1700021K10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270049
Homologene: 65137
Zfp607b
Name: zinc finger protein 607B
Synonyms: C030039L03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 112415
Homologene: 134321
Lonrf2
Name: LON peptidase N-terminal domain and ring finger 2
Synonyms: 2900060P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381338
Homologene: 18871
Cyp4f15
Name: cytochrome P450, family 4, subfamily f, polypeptide 15
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106648
Homologene: 80199
Ankrd9
Name: ankyrin repeat domain 9
Synonyms: 2500003O20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74251
Homologene: 17549
Pcdhac2
Name: protocadherin alpha subfamily C, 2
Synonyms: CNRc2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 353237
HGNC: HGNC:8677
Homologene: 49562
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 38,813,389 bp
  • T to A, chromosome 1 at 43,983,276 bp
  • A to T, chromosome 1 at 174,244,042 bp
  • A to T, chromosome 2 at 36,377,105 bp
  • A to C, chromosome 2 at 37,414,661 bp
  • A to G, chromosome 2 at 85,579,449 bp
  • A to T, chromosome 2 at 110,731,271 bp
  • G to A, chromosome 2 at 118,814,242 bp
  • A to T, chromosome 2 at 121,377,224 bp
  • A to G, chromosome 3 at 104,785,486 bp
  • T to C, chromosome 4 at 136,545,298 bp
  • T to A, chromosome 4 at 141,461,799 bp
  • G to A, chromosome 4 at 155,661,172 bp
  • A to T, chromosome 5 at 43,718,677 bp
  • T to C, chromosome 5 at 122,351,691 bp
  • T to A, chromosome 7 at 19,080,727 bp
  • T to C, chromosome 7 at 27,704,039 bp
  • T to A, chromosome 7 at 28,086,270 bp
  • T to A, chromosome 7 at 46,066,461 bp
  • A to G, chromosome 7 at 49,464,904 bp
  • CG to CGACGGCGGGG, chromosome 7 at 97,579,908 bp
  • A to T, chromosome 7 at 139,122,964 bp
  • T to C, chromosome 8 at 27,143,234 bp
  • G to T, chromosome 8 at 58,427,770 bp
  • T to G, chromosome 8 at 110,326,460 bp
  • A to T, chromosome 9 at 21,956,675 bp
  • A to T, chromosome 9 at 57,141,591 bp
  • T to A, chromosome 9 at 66,483,866 bp
  • T to C, chromosome 10 at 80,360,201 bp
  • T to A, chromosome 11 at 34,823,003 bp
  • C to T, chromosome 11 at 75,671,635 bp
  • A to G, chromosome 12 at 59,172,580 bp
  • A to T, chromosome 12 at 110,977,063 bp
  • T to G, chromosome 13 at 17,323,230 bp
  • G to T, chromosome 14 at 20,560,869 bp
  • A to G, chromosome 15 at 47,857,834 bp
  • A to T, chromosome 15 at 76,629,818 bp
  • A to G, chromosome 15 at 80,879,773 bp
  • G to T, chromosome 16 at 21,922,278 bp
  • T to A, chromosome 17 at 14,674,164 bp
  • C to A, chromosome 17 at 25,393,740 bp
  • T to A, chromosome 17 at 32,692,612 bp
  • A to T, chromosome 17 at 33,963,199 bp
  • A to G, chromosome 18 at 37,145,203 bp
  • T to A, chromosome 19 at 12,473,235 bp
  • A to T, chromosome 19 at 12,935,400 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6695 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044813-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.