Strain Name:
C57BL/6J-MtgxR6729Btlr/Mmmh
Stock Number:
044847-MU
Citation ID:
RRID:MMRRC_044847-MU
Other Names:
R6729 (G1)
Major Collection:

Strain Information

Zfp934
Name: zinc finger protein 934
Synonyms: 6720457D02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 77117
VEGA: 13
Synj2
Name: synaptojanin 2
Synonyms: SJ2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20975
Homologene: 117703
Cdkal1
Name: CDK5 regulatory subunit associated protein 1-like 1
Synonyms: 6620401C13Rik, 1190005B03Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68916
Homologene: 9830
Bltp3b
Name: bridge-like lipid transfer protein family member 3B
Synonyms: 4930506D01Rik, Uhrf1bp1l, E030041M21Rik, 2010319N22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75089
VEGA: 10
Homologene: 12590
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, AnkG, 2900054D09Rik, Ankyrin-3, Ankyrin-G
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Tcp1
Name: t-complex protein 1
Synonyms: c-cpn, p63, Tcp-1, Cct1, Tp63, CCT, Ccta, TRic
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21454
Homologene: 5656
Nceh1
Name: neutral cholesterol ester hydrolase 1
Synonyms: B230106I24Rik, CPO-BP, mKIAA1363, Aadacl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320024
Homologene: 23251
Rsph1
Name: radial spoke head 1 homolog (Chlamydomonas)
Synonyms: MCA, meichroacidin, Tsga2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22092
VEGA: 17
Homologene: 11905
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75288
Homologene: 45939
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Hug, Jbts17, 2410089E03Rik, b2b012Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73692
Homologene: 11315
AI182371
Name: expressed sequence AI182371
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98870
Homologene: 87268
Acad12
Name: acyl-Coenzyme A dehydrogenase family, member 12
Synonyms: 9330129D05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 338350
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
Apbb1
Name: amyloid beta precursor protein binding family B member 1
Synonyms: Fe65, Rir
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11785
HGNC: HGNC:581
Homologene: 898
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627743
Homologene: 129680
Or10n1
Name: olfactory receptor family 10 subfamily N member 1
Synonyms: Olfr148, MOR224-4, GA_x6K02T2PVTD-33310486-33311418, M30
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258498
VEGA: 9
Homologene: 128136
Psg21
Name: pregnancy-specific beta-1-glycoprotein 21
Synonyms: cea8, 1600019C01Rik, 1600026N13Rik, 1600025N01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72242
Homologene: 110989
Slc6a15
Name: solute carrier family 6 (neurotransmitter transporter), member 15
Synonyms: v7-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103098
VEGA: 10
Homologene: 18163
Tpte
Name: transmembrane phosphatase with tensin homology
Synonyms: Pten2, Vsp
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234129
Homologene: 50411
Or8b53
Name: olfactory receptor family 8 subfamily B member 53
Synonyms: Olfr920, GA_x6K02T2PVTD-32458442-32459374, MOR165-6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258783
VEGA: 9
Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Synonyms: Cyp17, p450c17, steroid 17-alpha hydroxylase
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13074
HGNC: HGNC:2593
Homologene: 73875
Or4d1
Name: olfactory receptor family 4 subfamily D member 1
Synonyms: GA_x6K02T2PAEV-9555122-9554181, Olfr464, MOR240-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258407
HGNC: HGNC:8293
Homologene: 44975
Slc43a3
Name: solute carrier family 43, member 3
Synonyms: SEEEG-1, Eeg1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 58207
Homologene: 40925
Tead2
Name: TEA domain family member 2
Synonyms: TEAD-2, Etdf, TEF-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21677
Homologene: 19662
Clca1
Name: chloride channel accessory 1
Synonyms: gob5, gob-5, Clca3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 23844
HGNC: HGNC:2015
Homologene: 984
Pcsk4
Name: proprotein convertase subtilisin/kexin type 4
Synonyms: PC4, SPC5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18551
HGNC: HGNC:8746
Homologene: 22495
Or4d10c
Name: olfactory receptor family 4 subfamily D member 10C
Synonyms: MOR239-1, GA_x6K02T2RE5P-2447610-2446675, Olfr1426
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258805
Homologene: 128079
Rabep2
Name: rabaptin, RAB GTPase binding effector protein 2
Synonyms: 2610011A08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70314
Homologene: 23489
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100101919
Homologene: 41287
Nedd9
Name: neural precursor cell expressed, developmentally down-regulated gene 9
Synonyms: Cas-L, CasL, HEF1, E230025G09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18003
VEGA: 13
HGNC: HGNC:7733
Homologene: 4669
Yod1
Name: YOD1 deubiquitinase
Synonyms: 9930028C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226418
Homologene: 13176
Atp6v1f
Name: ATPase, H+ transporting, lysosomal V1 subunit F
Synonyms: 1110004G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66144
Homologene: 3119
Gm13090
Name: predicted gene 13090
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 105704528
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 46,672,521 bp
  • G to A, chromosome 1 at 130,717,538 bp
  • G to T, chromosome 2 at 35,084,705 bp
  • T to C, chromosome 2 at 84,938,285 bp
  • T to A, chromosome 3 at 27,241,271 bp
  • A to G, chromosome 3 at 145,005,966 bp
  • A to T, chromosome 4 at 151,089,628 bp
  • A to T, chromosome 5 at 121,607,935 bp
  • A to G, chromosome 6 at 29,467,965 bp
  • T to A, chromosome 7 at 18,652,591 bp
  • A to G, chromosome 7 at 45,217,234 bp
  • A to T, chromosome 7 at 105,565,381 bp
  • T to C, chromosome 7 at 126,440,197 bp
  • G to T, chromosome 8 at 22,355,475 bp
  • A to G, chromosome 9 at 38,755,828 bp
  • A to T, chromosome 9 at 39,613,773 bp
  • T to C, chromosome 10 at 69,808,925 bp
  • T to C, chromosome 10 at 80,325,101 bp
  • T to A, chromosome 10 at 89,805,684 bp
  • T to C, chromosome 10 at 103,393,914 bp
  • G to A, chromosome 11 at 87,914,850 bp
  • G to A, chromosome 13 at 29,474,695 bp
  • A to G, chromosome 13 at 41,315,802 bp
  • A to T, chromosome 13 at 62,492,932 bp
  • T to G, chromosome 14 at 49,318,960 bp
  • A to G, chromosome 14 at 61,210,518 bp
  • T to C, chromosome 15 at 8,188,601 bp
  • T to A, chromosome 17 at 5,986,014 bp
  • G to A, chromosome 17 at 12,923,253 bp
  • C to A, chromosome 17 at 20,208,343 bp
  • A to G, chromosome 17 at 31,277,252 bp
  • T to A, chromosome 19 at 12,088,496 bp
  • A to G, chromosome 19 at 18,830,297 bp
  • A to G, chromosome 19 at 46,670,581 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6729 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044847-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.