Strain Name:
C57BL/6J-MtgxR6783Btlr/Mmmh
Stock Number:
044897-MU
Citation ID:
RRID:MMRRC_044897-MU
Other Names:
R6783 (G1)
Major Collection:

Strain Information

Dnmt3a
Name: DNA methyltransferase 3A
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13435
HGNC: HGNC:2978
Homologene: 7294
Sim1
Name: single-minded family bHLH transcription factor 1
Synonyms: bHLHe14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20464
VEGA: 10
Homologene: 3715
Epha7
Name: Eph receptor A7
Synonyms: MDK1, Hek11, Mdk1, Cek11, Ebk, Ehk3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13841
HGNC: HGNC:3390
Homologene: 20935
Csnk1g1
Name: casein kinase 1, gamma 1
Synonyms: 9130020E21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214897
HGNC: HGNC:2454
Homologene: 48692
Ski
Name: ski sarcoma viral oncogene homolog (avian)
Synonyms: 2610001A11Rik, 2310012I02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20481
Homologene: 31124
Ddx54
Name: DEAD box helicase 54
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 54, APR-5, 2410015A15Rik, DP97
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71990
Homologene: 5590
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194401
Homologene: 85288
Palb2
Name: partner and localizer of BRCA2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233826
Homologene: 11652
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
Ptcd3
Name: pentatricopeptide repeat domain 3
Synonyms: 2610034F17Rik, 2810422B04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69956
Homologene: 41211
Dpp8
Name: dipeptidylpeptidase 8
Synonyms: 4932434F09Rik, 2310004I03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74388
VEGA: 9
Homologene: 57098
Bcam
Name: basal cell adhesion molecule
Synonyms: 1200005K12Rik, Lu, B-CAM
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57278
HGNC: HGNC:6722
Homologene: 21149
Tent2
Name: terminal nucleotidyltransferase 2
Synonyms: Papd4, 8030446C20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100715
VEGA: 13
Homologene: 44022
Adam12
Name: ADAM metallopeptidase domain 12
Synonyms: ADAM12, Mltna
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11489
HGNC: HGNC:190
Homologene: 74862
Drap1
Name: DR1 associated protein 1
Synonyms: 2310074H19Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66556
HGNC: HGNC:3019
Homologene: 4703
Il31ra
Name: interleukin 31 receptor A
Synonyms: GLM-R, GPL
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218624
VEGA: 13
Homologene: 51395
Trim33
Name: tripartite motif-containing 33
Synonyms: ectodermin, Tif1g, Ecto, 8030451N04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 94093
Homologene: 9296
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229474
Homologene: 18920
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408066
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Grik3
Name: glutamate receptor, ionotropic, kainate 3
Synonyms: Glur7, Glur-7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14807
HGNC: HGNC:4581
Homologene: 73901
Ripk4
Name: receptor-interacting serine-threonine kinase 4
Synonyms: Ankrd3, PKK, RIP4, DIk, ANKK2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72388
HGNC: HGNC:496
Homologene: 10772
Rpap2
Name: RNA polymerase II associated protein 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231571
Homologene: 11733
Prpf40b
Name: pre-mRNA processing factor 40B
Synonyms: 2610317D23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54614
Homologene: 81828
Itga1
Name: integrin alpha 1
Synonyms: Vla1, CD49A, E130012M19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Serpinb10
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241197
HGNC: HGNC:8942
Homologene: 68430
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637908
Homologene: 104040
Cdr2l
Name: cerebellar degeneration-related protein 2-like
Synonyms: D030068L24Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237988
Homologene: 35390
Clcn4
Name: chloride channel, voltage-sensitive 4
Synonyms: Clcn4-2, Clc4-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12727
HGNC: HGNC:2022
Homologene: 68207
Bag6
Name: BCL2-associated athanogene 6
Synonyms: Scythe, 2410045D21Rik, G3, D17H6S52E, Bat3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224727
Homologene: 3409
Ddx31
Name: DEAD/H box helicase 31
Synonyms: 5830444G11Rik, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227674
Homologene: 6389
Far2
Name: fatty acyl CoA reductase 2
Synonyms: Mlstd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330450
Homologene: 69247
Pate8
Name: prostate and testis expressed 8
Synonyms: Gm17689
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100312948
Use1
Name: unconventional SNARE in the ER 1 homolog (S. cerevisiae)
Synonyms: Q-SNARE, 2010315L10Rik, D12, mED2, 5730403H22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67023
Homologene: 10214
Spaca7b
Name: sperm acrosome associated 7B
Synonyms: 1700016D06Rik, GC14
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76413
Trdn
Name: triadin
Synonyms: triadin-1, EG432451, triadin 3, triadin 1, 2310045H21Rik, triadin-2, triadin-3, triadin 2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76757
VEGA: 10
Homologene: 38137
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70719
Homologene: 69120
Or4n4
Name: olfactory receptor family 4 subfamily N member 4
Synonyms: GA_x6K02T2PMLR-5975274-5974348, Olfr732, MOR241-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258659
Homologene: 72012
Sgpp1
Name: sphingosine-1-phosphate phosphatase 1
Synonyms: SPP, SPP1, mSPP1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 81535
VEGA: 12
Homologene: 101696
Polm
Name: polymerase (DNA directed), mu
Synonyms: B230309I03Rik, Tdt-N
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54125
HGNC: HGNC:9185
Homologene: 41170
Vmn2r33
Name: vomeronasal 2, receptor 33
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 624512
Homologene: 113703
Or14c43
Name: olfactory receptor family 14 subfamily C member 43
Synonyms: GA_x6K02T2NHDJ-9643949-9642957, MOR221-2, Olfr299
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257929
Homologene: 115489
Gm10330
Name: predicted gene 10330
Type: Gene
Species: Mouse
Chromosome: 12
Pwwp4c
Name: PWWP domain containing 4C
Synonyms: Gm5640
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 434797
Homologene: 128534
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 107,546,867 bp
  • G to A, chromosome 2 at 28,874,176 bp
  • T to C, chromosome 3 at 84,445,527 bp
  • T to C, chromosome 3 at 103,352,087 bp
  • G to T, chromosome 4 at 28,950,528 bp
  • A to T, chromosome 4 at 125,632,300 bp
  • A to T, chromosome 4 at 155,160,832 bp
  • A to G, chromosome 5 at 107,655,287 bp
  • C to T, chromosome 5 at 120,618,714 bp
  • A to T, chromosome 6 at 71,908,643 bp
  • A to C, chromosome 6 at 120,958,825 bp
  • A to T, chromosome 6 at 146,385,873 bp
  • T to G, chromosome 6 at 148,150,775 bp
  • T to A, chromosome 7 at 7,299,182 bp
  • C to A, chromosome 7 at 7,563,798 bp
  • G to A, chromosome 7 at 12,601,433 bp
  • C to T, chromosome 7 at 19,766,881 bp
  • T to A, chromosome 7 at 86,465,627 bp
  • T to A, chromosome 7 at 122,127,488 bp
  • T to C, chromosome 7 at 131,226,764 bp
  • T to A, chromosome 7 at 133,974,397 bp
  • G to A, chromosome 8 at 11,655,661 bp
  • T to C, chromosome 8 at 71,369,236 bp
  • T to A, chromosome 9 at 36,581,335 bp
  • T to C, chromosome 9 at 65,063,562 bp
  • T to A, chromosome 9 at 65,973,512 bp
  • C to T, chromosome 10 at 33,438,815 bp
  • T to C, chromosome 10 at 50,908,727 bp
  • A to G, chromosome 10 at 80,017,864 bp
  • C to A, chromosome 11 at 5,835,534 bp
  • G to A, chromosome 11 at 23,412,318 bp
  • C to T, chromosome 11 at 115,393,669 bp
  • A to G, chromosome 12 at 3,897,406 bp
  • A to T, chromosome 12 at 23,780,093 bp
  • G to C, chromosome 12 at 75,735,469 bp
  • G to A, chromosome 13 at 93,155,018 bp
  • C to G, chromosome 13 at 93,155,019 bp
  • T to C, chromosome 13 at 112,551,988 bp
  • A to T, chromosome 13 at 113,320,209 bp
  • T to G, chromosome 13 at 114,996,977 bp
  • T to C, chromosome 14 at 50,282,187 bp
  • C to T, chromosome 15 at 99,314,903 bp
  • C to A, chromosome 16 at 97,748,037 bp
  • T to A, chromosome 17 at 35,144,235 bp
  • G to T, chromosome 19 at 5,424,191 bp
  • C to T, chromosome X at 74,640,415 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6783 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044897-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.