Strain Name:
C57BL/6J-MtgxR6795Btlr/Mmmh
Stock Number:
044908-MU
Citation ID:
RRID:MMRRC_044908-MU
Other Names:
R6795 (G1)
Major Collection:

Strain Information

Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 2500001H09Rik, 5730417B17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74737
Homologene: 32282
Birc2
Name: baculoviral IAP repeat-containing 2
Synonyms: IAP1, MIAP1, cIAP-1, mcIAP1, MIHB, HIAP1, Api1, cIAP1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11797
HGNC: HGNC:590
Homologene: 900
Agps
Name: alkylglycerone phosphate synthase
Synonyms: 9930035G10Rik, ADAPS, bs2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228061
HGNC: HGNC:327
Homologene: 2716
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: opm, A630086P08Rik, b2b327Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: C130099L13Rik, 8430405D05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
Slc30a5
Name: solute carrier family 30 (zinc transporter), member 5
Synonyms: ZTL1, Znt5, ZnT-5, Zntl1, 1810010K08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69048
VEGA: 13
Homologene: 41503
Synrg
Name: synergin, gamma
Synonyms: Ap1gbp1, L71-5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Gmds
Name: GDP-mannose 4, 6-dehydratase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218138
HGNC: HGNC:4369
Homologene: 75968
Ttf2
Name: transcription termination factor, RNA polymerase II
Synonyms: 4632434F22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74044
Homologene: 37826
Amfr
Name: autocrine motility factor receptor
Synonyms: gp78
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23802
HGNC: HGNC:463
Homologene: 888
Galnt2
Name: polypeptide N-acetylgalactosaminyltransferase 2
Synonyms: ppGaNTase-T2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 108148
HGNC: HGNC:4124
Homologene: 3297
Ephb2
Name: Eph receptor B2
Synonyms: Prkm5, Erk, eteck, Tyro5, Nuk, Cek5, Qek5, Sek3, Hek5, Drt
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13844
HGNC: HGNC:3393
Homologene: 37925
Or5d18
Name: olfactory receptor family 5 subfamily D member 18
Synonyms: MOR174-9, GA_x6K02T2Q125-49527073-49526132, mOR-EG, Olfr73
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 117004
Homologene: 133889
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Ces2g
Name: carboxylesterase 2G
Synonyms: 2210023G05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72361
HGNC: HGNC:1864
Homologene: 77154
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242627
Homologene: 135888
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Gm19410
Name: predicted gene, 19410
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 100502846
Homologene: 132117
Dpy19l1
Name: dpy-19 like C-mannosyltransferase 1
Synonyms: 1100001I19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244745
Homologene: 14762
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Sema5b
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Synonyms: Semag, SemG, SemG
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20357
Homologene: 8427
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Tbc1d31
Name: TBC1 domain family, member 31
Synonyms: Wdr67, LOC210544, D330013L20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 210544
Homologene: 17089
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74376
Homologene: 53435
Dlgap1
Name: DLG associated protein 1
Synonyms: Sapap1, SAPAP1, GKAP/SAPAP, 4933422O14Rik, D17Bwg0511e, DAP-1 beta, Gkap
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224997
HGNC: HGNC:2905
Homologene: 31258
Prpf38b
Name: PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
Synonyms: 1110021E09Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66921
Homologene: 9986
Calr4
Name: calreticulin 4
Synonyms: 4933403L16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 108802
Homologene: 86813
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: mPRg, 0610010I15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74090
Homologene: 9788
Vmn1r6
Name: vomeronasal 1 receptor 6
Synonyms: V1rc20
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171193
Homologene: 128340
Thnsl1
Name: threonine synthase-like 1 (bacterial)
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 208967
Homologene: 32609
Ces3a
Name: carboxylesterase 3A
Synonyms: Es-male carboxylesterase, Es31
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382053
HGNC: HGNC:1865
Homologene: 84407
Cenpn
Name: centromere protein N
Synonyms: 2610510J17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72155
Homologene: 12450
2310002L09Rik
Name: RIKEN cDNA 2310002L09 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71886
Homologene: 36448
Slc25a42
Name: solute carrier family 25, member 42
Synonyms: 2900084M01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73095
Homologene: 74852
Cd8b1
Name: CD8 subunit beta 1
Synonyms: Ly-C, Ly-3, Lyt-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12526
Homologene: 3621
Aadacl2fm3
Name: AADACL2 family member 3
Synonyms: Gm8298
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 666803
Homologene: 86204
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: Gm9813, LOC217602, EG639426, AU024163, 4921506M07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70846
Homologene: 78002
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 2 at 21,213,492 bp
  • A to G, chromosome 2 at 75,894,058 bp
  • A to T, chromosome 2 at 82,980,959 bp
  • C to T, chromosome 2 at 88,034,324 bp
  • A to T, chromosome 3 at 59,868,936 bp
  • G to A, chromosome 3 at 100,959,262 bp
  • T to C, chromosome 3 at 108,904,664 bp
  • C to A, chromosome 4 at 73,950,828 bp
  • A to G, chromosome 4 at 109,244,788 bp
  • C to T, chromosome 4 at 113,667,223 bp
  • A to C, chromosome 4 at 136,673,335 bp
  • T to C, chromosome 5 at 112,846,364 bp
  • A to G, chromosome 6 at 57,002,437 bp
  • T to A, chromosome 6 at 71,326,340 bp
  • T to A, chromosome 6 at 121,648,322 bp
  • A to C, chromosome 7 at 92,657,578 bp
  • G to A, chromosome 8 at 35,795,522 bp
  • A to G, chromosome 8 at 70,188,390 bp
  • A to G, chromosome 8 at 94,000,333 bp
  • A to G, chromosome 8 at 104,967,817 bp
  • G to A, chromosome 8 at 105,050,596 bp
  • T to A, chromosome 8 at 116,926,148 bp
  • T to A, chromosome 8 at 123,318,493 bp
  • T to C, chromosome 8 at 124,343,436 bp
  • A to G, chromosome 9 at 7,833,872 bp
  • C to A, chromosome 9 at 24,502,862 bp
  • C to T, chromosome 9 at 61,963,783 bp
  • G to A, chromosome 10 at 107,777,117 bp
  • A to G, chromosome 11 at 72,850,659 bp
  • A to G, chromosome 11 at 84,019,914 bp
  • A to G, chromosome 12 at 51,794,487 bp
  • T to C, chromosome 12 at 57,704,413 bp
  • C to T, chromosome 13 at 32,234,352 bp
  • A to T, chromosome 13 at 100,817,069 bp
  • A to G, chromosome 15 at 57,951,706 bp
  • T to C, chromosome 15 at 76,180,138 bp
  • T to A, chromosome 16 at 35,658,571 bp
  • C to A, chromosome 17 at 70,818,074 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6795 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044908-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.