Strain Name:
C57BL/6J-MtgxR6796Btlr/Mmmh
Stock Number:
044909-MU
Citation ID:
RRID:MMRRC_044909-MU
Other Names:
R6796 (G1)
Major Collection:

Strain Information

Map4k5
Name: mitogen-activated protein kinase kinase kinase kinase 5
Synonyms: MAPKKKK5, GCKR, KHS, 4432415E19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 399510
HGNC: HGNC:6867
Homologene: 38199
App
Name: amyloid beta precursor protein
Synonyms: betaAPP, Abeta, protease nexin II, Adap, Cvap, appican, E030013M08Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11820
VEGA: 16
HGNC: HGNC:620
Homologene: 56379
Ranbp17
Name: RAN binding protein 17
Synonyms: 4932704E15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66011
Homologene: 36409
Utp23
Name: UTP23 small subunit processome component
Synonyms: 1700010I21Rik, D530033C11Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 78581
Homologene: 41789
E2f3
Name: E2F transcription factor 3
Synonyms: E2F3b, E2f3a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13557
HGNC: HGNC:3115
Homologene: 74413
Scaper
Name: S phase cyclin A-associated protein in the ER
Synonyms: D530014O03Rik, Zfp291
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244891
VEGA: 9
Homologene: 32488
Taf12
Name: TATA-box binding protein associated factor 12
Synonyms: Taf2J, 2810422D08Rik, 20kDa
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66464
Homologene: 68477
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Rnd2
Name: Rho family GTPase 2
Synonyms: Arhn, Rohn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11858
Homologene: 21123
Selenow
Name: selenoprotein W
Synonyms: Sepw1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20364
Homologene: 2263
Rpl34
Name: ribosomal protein L34
Synonyms: 1100001I22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68436
Homologene: 105146
Fcer2a
Name: Fc receptor, IgE, low affinity II, alpha polypeptide
Synonyms: low-affinity IgE receptor, FC epsilon RII, Fce2, Ly-42, CD23
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14128
HGNC: HGNC:3612
Homologene: 1517
Plcd4
Name: phospholipase C, delta 4
Synonyms: 4921507K24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18802
HGNC: HGNC:9062
Homologene: 88782
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, D430029O09Rik, 1110021D17Rik, Polydom
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64817
Homologene: 23386
Mcc
Name: mutated in colorectal cancers
Synonyms: D18Ertd451e
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 328949
HGNC: HGNC:6935
Homologene: 20539
Insrr
Name: insulin receptor-related receptor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 23920
HGNC: HGNC:6093
Homologene: 56539
Sis
Name: sucrase isomaltase
Synonyms: Si-s, sucrase-isomaltase, 2010204N08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69983
Homologene: 37424
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 378425
Homologene: 16972
Rpgrip1
Name: retinitis pigmentosa GTPase regulator interacting protein 1
Synonyms: 4930505G06Rik, A930002K18Rik, 4930401L23Rik, nmf247
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 77945
Homologene: 10679
Dpy19l1
Name: dpy-19 like C-mannosyltransferase 1
Synonyms: 1100001I19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244745
Homologene: 14762
Bpifb4
Name: BPI fold containing family B, member 4
Synonyms: LOC381399, Gm1006
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381399
Homologene: 66971
Or5an6
Name: olfactory receptor family 5 subfamily AN member 6
Synonyms: GA_x6K02T2RE5P-2725206-2726153, MOR215-1, Olfr1440
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258679
Homologene: 128133
Tmc1
Name: transmembrane channel-like gene family 1
Synonyms: Bth, Beethoven, 4933416G09Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13409
VEGA: 19
Homologene: 23670
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Krc, E030045D18Rik, 2900056N03Rik, Shn3, Schnurri-3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16656
Homologene: 7803
Sit1
Name: suppression inducing transmembrane adaptor 1
Synonyms: Sit
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 54390
Homologene: 8694
Lin37
Name: lin-37 DREAM MuvB core complex component
Synonyms: 1810054G18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75660
Homologene: 12616
Itgax
Name: integrin alpha X
Synonyms: CD11C (p150) alpha polypeptide, Cd11c, CR4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Proca1
Name: protein interacting with cyclin A1
Synonyms: 4933404M19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216974
Homologene: 51856
Pom121l2
Name: POM121 transmembrane nucleoporin like 2
Synonyms: LOC195236
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 195236
Homologene: 123536
Or5b119
Name: olfactory receptor family 5 subfamily B member 119
Synonyms: GA_x6K02T2RE5P-3812807-3811863, MOR202-36, Olfr1475
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258298
Homologene: 77370
Tas2r139
Name: taste receptor, type 2, member 139
Synonyms: mt2r34, Tas2r39
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353148
Homologene: 52214
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: 0610010I15Rik, mPRg
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74090
Homologene: 9788
Poglut1
Name: protein O-glucosyltransferase 1
Synonyms: 9630046K23Rik, Ktelc1, Rumi, wsnp
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224143
Homologene: 41353
Septin14
Name: septin 14
Synonyms: 1700016K13Rik, Sept14
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74222
Homologene: 87501
Prr30
Name: proline rich 30
Synonyms: 1700110M21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76627
Homologene: 130773
Hcar2
Name: hydroxycarboxylic acid receptor 2
Synonyms: PUMA-G, HM74, Pumag, Gpr109b, Gpr109a, Niacr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80885
Homologene: 4391
Pax8
Name: paired box 8
Synonyms: Pax-8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18510
HGNC: HGNC:8622
Homologene: 2589
Susd3
Name: sushi domain containing 3
Synonyms: 2810440J20Rik, 1700017I11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66329
Homologene: 11948
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Gm13318, Gm13364, Diet1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102635496
Homologene: 136214
F930015N05Rik
Name: RIKEN cDNA F930015N05 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 654805
VEGA: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 74,562,070 bp
  • T to A, chromosome 2 at 15,869,784 bp
  • A to T, chromosome 2 at 24,441,086 bp
  • A to T, chromosome 2 at 153,961,547 bp
  • A to T, chromosome 3 at 72,965,618 bp
  • C to T, chromosome 3 at 87,813,566 bp
  • G to T, chromosome 3 at 130,729,277 bp
  • A to T, chromosome 4 at 43,482,761 bp
  • A to G, chromosome 4 at 58,064,275 bp
  • A to G, chromosome 4 at 120,096,361 bp
  • G to A, chromosome 4 at 132,289,414 bp
  • A to G, chromosome 5 at 123,865,267 bp
  • T to A, chromosome 5 at 129,697,758 bp
  • A to T, chromosome 6 at 42,141,592 bp
  • T to C, chromosome 7 at 3,241,409 bp
  • A to T, chromosome 7 at 15,920,071 bp
  • A to T, chromosome 7 at 30,556,916 bp
  • C to T, chromosome 7 at 128,135,064 bp
  • T to C, chromosome 8 at 3,689,830 bp
  • C to A, chromosome 9 at 24,502,862 bp
  • T to C, chromosome 9 at 55,864,427 bp
  • C to T, chromosome 9 at 61,963,783 bp
  • T to C, chromosome 11 at 33,217,398 bp
  • A to T, chromosome 11 at 64,435,403 bp
  • G to T, chromosome 11 at 78,194,928 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • T to C, chromosome 12 at 69,818,025 bp
  • T to C, chromosome 13 at 21,983,524 bp
  • A to G, chromosome 13 at 29,918,585 bp
  • ACC to AC, chromosome 13 at 49,237,565 bp
  • A to G, chromosome 13 at 81,472,478 bp
  • A to G, chromosome 14 at 52,150,012 bp
  • A to G, chromosome 14 at 101,198,944 bp
  • T to A, chromosome 15 at 23,446,073 bp
  • T to A, chromosome 15 at 51,877,611 bp
  • C to T, chromosome 16 at 18,784,857 bp
  • T to C, chromosome 16 at 38,529,610 bp
  • A to G, chromosome 16 at 85,120,567 bp
  • A to G, chromosome 18 at 44,724,560 bp
  • A to T, chromosome 19 at 12,394,928 bp
  • A to G, chromosome 19 at 13,479,914 bp
  • A to T, chromosome 19 at 20,799,036 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6796 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044909-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.