Strain Name:
C57BL/6J-MtgxR6810Btlr/Mmmh
Stock Number:
044923-MU
Citation ID:
RRID:MMRRC_044923-MU
Other Names:
R6810 (G1)
Major Collection:

Strain Information

Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: GENA 60, GENA 47, Gena 52, Cyn, A730019I05Rik, WBE1, Whi, Todo, Obt, Mt, Lda, Flo, Edy, Dz, Cycn
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320790
Homologene: 19067
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Triobp
Name: TRIO and F-actin binding protein
Synonyms: Mus EST 478828, Tara, EST478828
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110253
Homologene: 5104
Snd1
Name: staphylococcal nuclease and tudor domain containing 1
Synonyms: p100 co-activator, Tudor-SN
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56463
Homologene: 8665
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12211
Homologene: 7248
Ptcd3
Name: pentatricopeptide repeat domain 3
Synonyms: 2610034F17Rik, 2810422B04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69956
Homologene: 41211
Mlh1
Name: mutL homolog 1
Synonyms: colon cancer, nonpolyposis type 2, 1110035C23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17350
HGNC: HGNC:7127
Homologene: 208
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Dcc
Name: DCC netrin 1 receptor
Synonyms: C030036D22Rik, Igdcc1, deleted in colorectal carcinoma
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13176
HGNC: HGNC:2701
Homologene: 21081
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: l(7)-3Rn, Ten-m4, Doc4, l7Rn3, ELM2, Odz4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23966
Homologene: 8034
Adgrg5
Name: adhesion G protein-coupled receptor G5
Synonyms: LOC382045, PGR27, Gpr114
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382045
Homologene: 17828
Cdk2
Name: cyclin dependent kinase 2
Synonyms: A630093N05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12566
VEGA: 10
HGNC: HGNC:1771
Homologene: 74409
Tes
Name: testin LIM domain protein
Synonyms: Tes2, Tes1, testin2, testin, D6Ertd352e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21753
Homologene: 41051
Cenpe
Name: centromere protein E
Synonyms: N-7 kinesin, CENP-E, 312kDa, Kif10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Psrc1
Name: proline/serine-rich coiled-coil 1
Synonyms: DDA3, 5430413I02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56742
Homologene: 49603
Zfp748
Name: zinc finger protein 748
Synonyms: 2610014M12Rik, mszf54, KRAB-O, Zfp208
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212276
Homologene: 134552
Eif5b
Name: eukaryotic translation initiation factor 5B
Synonyms: IF2, A030003E17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226982
Homologene: 134613
Nhlrc3
Name: NHL repeat containing 3
Synonyms: 8030451K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 212114
Homologene: 35239
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Tgfbi
Name: transforming growth factor, beta induced
Synonyms: bIG-h3, 68kDa, Beta-ig
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21810
VEGA: 13
Homologene: 37294
C7
Name: complement component 7
Synonyms: LOC383055
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109828
VEGA: 15
HGNC: HGNC:1346
Homologene: 489
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227334
Homologene: 32400
Tnn
Name: tenascin N
Synonyms: Tnw, tenascin-W
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329278
Homologene: 18634
Tfip11
Name: tuftelin interacting protein 11
Synonyms: Tip39
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54723
Homologene: 40813
Tmx4
Name: thioredoxin-related transmembrane protein 4
Synonyms: 4930500L08Rik, 2810417D04Rik, D2Bwg1356e, Txndc13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 52837
Homologene: 10901
Rab11fip1
Name: RAB11 family interacting protein 1 (class I)
Synonyms: 2010200K21Rik, 4833414G05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75767
Homologene: 11853
Gm19410
Name: predicted gene, 19410
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 100502846
Homologene: 132117
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230622
Homologene: 135888
Aox3
Name: aldehyde oxidase 3
Synonyms: AOH1, 1200011D03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71724
Homologene: 90899
Slc24a1
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214111
VEGA: 9
Homologene: 3472
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Nell2
Name: NEL-like 2
Synonyms: mel91, A330108N19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54003
VEGA: 15
HGNC: HGNC:7751
Homologene: 4488
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Klhdc7b
Name: kelch domain containing 7B
Synonyms: EG546648
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 546648
Homologene: 34707
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: C820004H04Rik, LL5beta, LL5b
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208177
Homologene: 17100
Vmn2r99
Name: vomeronasal 2, receptor 99
Synonyms: EG665376
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665376
Homologene: 115024
Plscr4
Name: phospholipid scramblase 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235527
Homologene: 23217
Nlrp4c
Name: NLR family, pyrin domain containing 4C
Synonyms: Nalp-alpha, Rnh2, Nalp4c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83564
Homologene: 75315
Or5j3
Name: olfactory receptor family 5 subfamily J member 3
Synonyms: GA_x6K02T2Q125-47777498-47778436, MOR172-1, Olfr1052
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259012
Homologene: 79679
Hook3
Name: hook microtubule tethering protein 3
Synonyms: E330005F07Rik, 5830454D03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320191
Homologene: 13022
Zfp707
Name: zinc finger protein 707
Synonyms: 1500031N24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69020
Homologene: 18364
Semp2l2b
Name: SUMO/sentrin specific peptidase 2-like 2B
Synonyms: 4930444G20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 114671
Homologene: 130042
Fut2
Name: fucosyltransferase 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14344
HGNC: HGNC:4013
Homologene: 10325
Or51g1
Name: olfactory receptor family 51 subfamily G member 1
Synonyms: GA_x6K02T2PBJ9-5696486-5695545, MOR7-1, Olfr578
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259119
Homologene: 17513
Ivd
Name: isovaleryl coenzyme A dehydrogenase
Synonyms: 6720455E18Rik, 1300016K07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56357
HGNC: HGNC:6186
Homologene: 1676
Cd27
Name: CD27 antigen
Synonyms: Cd27, S152, Tp55, Tnfrsf7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21940
Homologene: 74386
Dio1
Name: deiodinase, iodothyronine, type I
Synonyms: D1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13370
HGNC: HGNC:2883
Homologene: 620
Pcdhga12
Name: protocadherin gamma subfamily A, 12
Synonyms: pc2c, Pcdh13
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93724
HGNC: HGNC:8699
Homologene: 134588
Adora1
Name: adenosine A1 receptor
Synonyms: A1AR, A1R, A1-AR, Ri, AA1R, ARA1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11539
HGNC: HGNC:262
Homologene: 20165
Pcdhga7
Name: protocadherin gamma subfamily A, 7
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93715
HGNC: HGNC:8705
Homologene: 36377
Ndufa3
Name: NADH:ubiquinone oxidoreductase subunit A3
Synonyms: 1010001M12Rik, 1700022J01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66091
HGNC: HGNC:7686
Homologene: 3338
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 34,212,298 bp
  • A to G, chromosome 1 at 38,046,660 bp
  • T to A, chromosome 1 at 58,141,431 bp
  • T to C, chromosome 1 at 87,981,033 bp
  • T to C, chromosome 1 at 134,234,039 bp
  • G to T, chromosome 1 at 160,104,842 bp
  • T to A, chromosome 1 at 164,186,902 bp
  • G to A, chromosome 2 at 86,297,923 bp
  • G to T, chromosome 2 at 118,869,761 bp
  • A to C, chromosome 2 at 134,620,674 bp
  • T to C, chromosome 3 at 53,453,575 bp
  • A to T, chromosome 3 at 108,385,348 bp
  • A to G, chromosome 3 at 135,243,822 bp
  • T to C, chromosome 4 at 8,839,523 bp
  • A to G, chromosome 4 at 107,297,725 bp
  • T to C, chromosome 4 at 112,948,380 bp
  • T to A, chromosome 5 at 62,814,329 bp
  • T to A, chromosome 5 at 112,333,597 bp
  • C to A, chromosome 6 at 17,104,652 bp
  • T to A, chromosome 6 at 28,668,610 bp
  • A to G, chromosome 6 at 32,310,522 bp
  • A to C, chromosome 6 at 71,885,532 bp
  • A to T, chromosome 6 at 125,233,664 bp
  • A to T, chromosome 7 at 3,619,477 bp
  • T to A, chromosome 7 at 6,066,755 bp
  • A to G, chromosome 7 at 45,650,505 bp
  • G to A, chromosome 7 at 96,553,496 bp
  • A to C, chromosome 7 at 102,984,835 bp
  • A to C, chromosome 8 at 26,032,422 bp
  • ACTCT to ACT, chromosome 8 at 27,152,732 bp
  • C to A, chromosome 8 at 35,772,579 bp
  • A to T, chromosome 8 at 94,933,942 bp
  • A to C, chromosome 8 at 123,286,477 bp
  • A to G, chromosome 9 at 64,948,323 bp
  • G to A, chromosome 9 at 92,483,836 bp
  • G to A, chromosome 9 at 111,241,558 bp
  • C to T, chromosome 10 at 22,066,717 bp
  • A to G, chromosome 10 at 128,699,587 bp
  • T to C, chromosome 11 at 48,888,976 bp
  • T to C, chromosome 11 at 55,282,241 bp
  • A to T, chromosome 11 at 83,335,491 bp
  • C to T, chromosome 12 at 75,942,885 bp
  • T to C, chromosome 13 at 56,637,203 bp
  • T to C, chromosome 13 at 67,541,725 bp
  • A to G, chromosome 15 at 5,007,654 bp
  • T to A, chromosome 15 at 75,974,899 bp
  • A to G, chromosome 15 at 78,966,615 bp
  • A to G, chromosome 15 at 89,388,356 bp
  • T to C, chromosome 15 at 95,241,587 bp
  • A to G, chromosome 16 at 45,748,725 bp
  • A to G, chromosome 17 at 19,380,034 bp
  • G to A, chromosome 17 at 74,612,220 bp
  • A to T, chromosome 18 at 37,715,873 bp
  • T to C, chromosome 18 at 37,767,179 bp
  • C to T, chromosome 18 at 71,370,693 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6810 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044923-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.