Strain Name:
C57BL/6J-MtgxR6813Btlr/Mmmh
Stock Number:
044925-MU
Citation ID:
RRID:MMRRC_044925-MU
Other Names:
R6813 (G1)
Major Collection:

Strain Information

Ppp1r1b
Name: protein phosphatase 1, regulatory inhibitor subunit 1B
Synonyms: DARPP-32, Darpp32
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19049
HGNC: HGNC:9287
Homologene: 12972
Il4i1
Name: interleukin 4 induced 1
Synonyms: H-46, Fig1, H4, H-4, Fig1-ps, H46
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14204
Homologene: 22567
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Ncoa7
Name: nuclear receptor coactivator 7
Synonyms: 9030406N13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 211329
VEGA: 10
Homologene: 65245
Cdc42bpb
Name: CDC42 binding protein kinase beta
Synonyms: DMPK-like
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217866
VEGA: 12
HGNC: HGNC:1738
Homologene: 55945
Dab2ip
Name: disabled 2 interacting protein
Synonyms: AIP1, 2310011D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69601
Homologene: 13058
Slc30a7
Name: solute carrier family 30 (zinc transporter), member 7
Synonyms: 2610034N15Rik, 4833428C12Rik, ZnT-7, ZnT7, 1810059J10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66500
Homologene: 11332
Wdr3
Name: WD repeat domain 3
Synonyms: D030020G18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269470
Homologene: 4937
Myo9b
Name: myosin IXb
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Phka2
Name: phosphorylase kinase alpha 2
Synonyms: k, Phk, 6330505C01Rik
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 110094
HGNC: HGNC:8926
Homologene: 246
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: D330037A14Rik, LL5A
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102693
Homologene: 15903
Myc
Name: myelocytomatosis oncogene
Synonyms: bHLHe39, Myc2, Niard, Nird, c-myc
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17869
HGNC: HGNC:7553
Homologene: 31092
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Arfgap3
Name: ADP-ribosylation factor GTPase activating protein 3
Synonyms: 1810035F16Rik, 0610009H19Rik, 1810004P07Rik, 9130416J18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66251
VEGA: 15
HGNC: HGNC:661
Homologene: 134103
Creld1
Name: cysteine-rich with EGF-like domains 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171508
Homologene: 32265
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: LOC381628, Gpr113, PGR23
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381628
Homologene: 17826
Eps15
Name: epidermal growth factor receptor pathway substrate 15
Synonyms: 2410112D09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13858
HGNC: HGNC:3419
Homologene: 128359
Ccdc25
Name: coiled-coil domain containing 25
Synonyms: 2610528H13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67179
VEGA: 14
Homologene: 6645
Lsm1
Name: LSM1 homolog, mRNA degradation associated
Synonyms: U6 small nuclear RNA associated, 2810025O06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67207
Homologene: 40945
Wtap
Name: WT1 associating protein
Synonyms: 2810408K05Rik, 9430038B09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 60532
Homologene: 68422
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: wmfl, Flk-2, CD135, Flk2, Flt-3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Zfp808
Name: zinc finger protein 808
Synonyms: Gm7036
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 630579
Homologene: 134631
Scnn1g
Name: sodium channel, nonvoltage-gated 1 gamma
Synonyms: ENaC gamma
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20278
Homologene: 20280
Ppp1r3a
Name: protein phosphatase 1, regulatory subunit 3A
Synonyms: GM, RGL
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 140491
HGNC: HGNC:9291
Homologene: 48124
Il12rb2
Name: interleukin 12 receptor, beta 2
Synonyms: A930027I18Rik, Ifnm, IL-12RB2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16162
HGNC: HGNC:5972
Homologene: 1197
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69239
Homologene: 130756
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Or10g9b
Name: olfactory receptor family 10 subfamily G member 9B
Synonyms: Olfr980, GA_x6K02T2PVTD-33705428-33704496, MOR223-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 259110
VEGA: 9
Homologene: 81557
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: 2410089E03Rik, Jbts17, b2b012Clo, Hug
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73692
Homologene: 11315
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: Myhs-f2, IId/x, IId, A530084A17Rik, MyHC-IId/x, Myhsf2, myosin heavy chain 2X, MYHC-IIX, Myhs-f
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Clstn3
Name: calsyntenin 3
Synonyms: Cst-3, CSTN3, alcadein-beta, Clstn3b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232370
Homologene: 22836
Irs2
Name: insulin receptor substrate 2
Synonyms: Irs-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 384783
HGNC: HGNC:6126
Homologene: 2778
Dnai4
Name: dynein axonemal intermediate chain 4
Synonyms: Wdr78
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242584
Homologene: 11702
Ephb1
Name: Eph receptor B1
Synonyms: Elkh, Elk, Cek6, C130099E04Rik, Hek6, Net
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270190
HGNC: HGNC:3392
Homologene: 20936
Dlec1
Name: deleted in lung and esophageal cancer 1
Synonyms: D630005C06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320256
HGNC: HGNC:2899
Homologene: 84733
Fam111a
Name: family with sequence similarity 111, member A
Synonyms: 4632417K18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107373
Homologene: 49696
Or2t44
Name: olfactory receptor family 2 subfamily T member 44
Synonyms: MOR278-2, GA_x6K02T2NKPP-622179-621244, Olfr314
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 257917
Homologene: 133891
Disp3
Name: dispatched RND transporter family member 3
Synonyms: Ptchd2, G630052C06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242748
Homologene: 25712
Rasgrf1
Name: RAS protein-specific guanine nucleotide-releasing factor 1
Synonyms: CDC25, Grfbeta, CDC25Mm, Grf1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19417
HGNC: HGNC:9875
Homologene: 74972
Atxn7l1
Name: ataxin 7-like 1
Synonyms: 2810423G08Rik, Atxn7l4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380753
Homologene: 53366
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 433070
Or7g16
Name: olfactory receptor family 7 subfamily G member 16
Synonyms: MOR149-1, GA_x6K02T2PVTD-12559294-12558356, Olfr828
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258598
HGNC: HGNC:8466
Homologene: 133690
Vmn2r81
Name: vomeronasal 2, receptor 81
Synonyms: EC1-VR2, V2rf2, pheromone recepter
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216144
Homologene: 83483
Brsk2
Name: BR serine/threonine kinase 2
Synonyms: 4833424K13Rik, SAD-A
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75770
Homologene: 123829
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: Del-1, developmental endothelial locus-1, Del1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Pccb
Name: propionyl Coenzyme A carboxylase, beta polypeptide
Synonyms: 1300012P06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66904
HGNC: HGNC:8654
Homologene: 447
Pdp2
Name: pyruvate dehydrogenase phosphatase catalytic subunit 2
Synonyms: 4833426J09Rik, LOC382051
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382051
Homologene: 36388
Ifih1
Name: interferon induced with helicase C domain 1
Synonyms: Helicard, 9130009C22Rik, MDA-5, MDA5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71586
Homologene: 32535
Ttc29
Name: tetratricopeptide repeat domain 29
Synonyms: 1700031F13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73301
Homologene: 12918
Tmem33
Name: transmembrane protein 33
Synonyms: 1110006G02Rik, 5430406L04Rik, 2410089A21Rik, 2700052H22Rik, 1600019D15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67878
Homologene: 10018
Asb13
Name: ankyrin repeat and SOCS box-containing 13
Synonyms: 6430573K02Rik, 2210015B19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 142688
Homologene: 11666
Tmem30c
Name: transmembrane protein 30C
Synonyms: 4933409A18Rik, 4933401B01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71027
Homologene: 78138
Frmd3
Name: FERM domain containing 3
Synonyms: 4.1O, 9430066I12Rik, EPB41L4O, P410
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242506
Homologene: 16012
Vamp5
Name: vesicle-associated membrane protein 5
Synonyms: Camp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 53620
Homologene: 4833
Or8b9
Name: olfactory receptor family 8 subfamily B member 9
Synonyms: Olfr877, GA_x6K02T2PVTD-31540342-31541277, MOR161-5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258412
Homologene: 121556
Or8b36
Name: olfactory receptor family 8 subfamily B member 36
Synonyms: GA_x6K02T2PVTD-31705144-31706073, Olfr883, MOR162-6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258414
Homologene: 86689
Dcun1d4
Name: defective in cullin neddylation 1 domain containing 4
Synonyms: DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100737
Homologene: 22867
Csf1r
Name: colony stimulating factor 1 receptor
Synonyms: CD115, Fms, Fim2, M-CSFR, CSF-1R, Csfmr, Fim-2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12978
HGNC: HGNC:2433
Homologene: 3817
Epha10
Name: Eph receptor A10
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230735
Homologene: 67804
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mouse
Chromosome: 7
Hsfy2
Name: heat shock transcription factor, Y-linked 2
Synonyms: 4933413G11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71066
Homologene: 134090
Pvrig
Name: poliovirus receptor related immunoglobulin domain containing
Synonyms: Gm36869
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 102640920
Homologene: 78229
Spata31e1
Name: spermatogenesis associated 31 subfamily E member 1
Synonyms: Gm30302
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 102632152
VEGA: 13
Homologene: 141176
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 56,636,302 bp
  • C to T, chromosome 2 at 35,730,473 bp
  • C to T, chromosome 2 at 62,645,693 bp
  • G to A, chromosome 3 at 100,138,725 bp
  • A to T, chromosome 3 at 115,981,811 bp
  • T to C, chromosome 4 at 74,159,245 bp
  • T to C, chromosome 4 at 103,048,326 bp
  • T to A, chromosome 4 at 109,280,402 bp
  • T to A, chromosome 4 at 124,902,693 bp
  • C to A, chromosome 4 at 130,009,491 bp
  • G to A, chromosome 4 at 148,259,930 bp
  • A to G, chromosome 5 at 30,197,521 bp
  • T to C, chromosome 5 at 67,264,459 bp
  • C to A, chromosome 5 at 73,520,957 bp
  • A to T, chromosome 5 at 138,342,050 bp
  • T to C, chromosome 5 at 147,354,843 bp
  • A to G, chromosome 6 at 14,719,571 bp
  • A to T, chromosome 6 at 40,750,165 bp
  • A to C, chromosome 6 at 67,292,374 bp
  • G to A, chromosome 6 at 72,380,441 bp
  • A to G, chromosome 6 at 113,489,569 bp
  • T to A, chromosome 6 at 124,436,935 bp
  • T to C, chromosome 7 at 3,736,003 bp
  • A to G, chromosome 7 at 44,839,812 bp
  • T to C, chromosome 7 at 121,740,353 bp
  • A to G, chromosome 7 at 142,002,477 bp
  • G to A, chromosome 8 at 11,004,659 bp
  • T to G, chromosome 8 at 25,793,693 bp
  • A to G, chromosome 8 at 71,323,305 bp
  • A to T, chromosome 8 at 78,333,620 bp
  • C to T, chromosome 8 at 104,594,499 bp
  • G to A, chromosome 9 at 18,815,892 bp
  • A to C, chromosome 9 at 37,855,514 bp
  • T to C, chromosome 9 at 38,025,833 bp
  • T to A, chromosome 9 at 40,006,457 bp
  • A to T, chromosome 9 at 44,699,568 bp
  • T to G, chromosome 9 at 53,497,235 bp
  • G to A, chromosome 9 at 90,010,484 bp
  • A to G, chromosome 9 at 101,023,215 bp
  • A to G, chromosome 9 at 102,010,048 bp
  • C to T, chromosome 9 at 105,783,941 bp
  • A to T, chromosome 9 at 119,112,102 bp
  • T to A, chromosome 10 at 30,696,192 bp
  • T to A, chromosome 10 at 79,268,605 bp
  • G to T, chromosome 11 at 58,786,646 bp
  • T to C, chromosome 11 at 67,220,460 bp
  • T to A, chromosome 11 at 98,349,176 bp
  • T to C, chromosome 12 at 33,367,124 bp
  • A to G, chromosome 12 at 111,327,615 bp
  • G to T, chromosome 13 at 3,645,029 bp
  • T to A, chromosome 13 at 49,787,396 bp
  • T to C, chromosome 13 at 62,173,035 bp
  • T to A, chromosome 13 at 89,289,456 bp
  • T to A, chromosome 14 at 65,856,433 bp
  • T to A, chromosome 15 at 8,229,282 bp
  • T to C, chromosome 15 at 61,988,152 bp
  • A to T, chromosome 15 at 83,330,593 bp
  • A to G, chromosome 16 at 57,281,259 bp
  • A to T, chromosome 17 at 12,967,510 bp
  • A to G, chromosome 17 at 18,581,854 bp
  • G to T, chromosome 17 at 58,974,436 bp
  • T to A, chromosome 18 at 61,112,734 bp
  • T to A, chromosome 19 at 12,587,342 bp
  • G to A, chromosome X at 160,533,048 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6813 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044925-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.