Strain Name:
C57BL/6J-MtgxR6830Btlr/Mmmh
Stock Number:
044940-MU
Citation ID:
RRID:MMRRC_044940-MU
Other Names:
R6830 (G1)
Major Collection:

Strain Information

Fgb
Name: fibrinogen beta chain
Synonyms: 2510049G14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 110135
HGNC: HGNC:3662
Homologene: 3772
Ldb2
Name: LIM domain binding 2
Synonyms: CLIM1, CLIM-1a, CLIM-1b, CLP-36, Ldb3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16826
HGNC: HGNC:6533
Homologene: 989
Plekhm1
Name: pleckstrin homology domain containing, family M (with RUN domain) member 1
Synonyms: AP162, D330036J23Rik, B2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 353047
Homologene: 8871
Dock9
Name: dedicator of cytokinesis 9
Synonyms: B230309H04Rik, Zizimin1, D14Wsu89e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105445
Homologene: 41026
Prep
Name: prolyl endopeptidase
Synonyms: Pop, prolyl oligopeptidase, D10Wsu136e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19072
VEGA: 10
HGNC: HGNC:9358
Homologene: 2042
Ano6
Name: anoctamin 6
Synonyms: 2900059G15Rik, F730003B03Rik, Tmem16f
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105722
VEGA: 15
Homologene: 27888
Ttc27
Name: tetratricopeptide repeat domain 27
Synonyms: 2610511O17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74196
VEGA: 17
Homologene: 41191
Stk38l
Name: serine/threonine kinase 38 like
Synonyms: 4930473A22Rik, Ndr2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232533
Homologene: 56299
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Zbtb21
Name: zinc finger and BTB domain containing 21
Synonyms: Zfp295, Znf295, B430213I24Rik, 5430437K12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 114565
VEGA: 16
Homologene: 10799
Ptprc
Name: protein tyrosine phosphatase receptor type C
Synonyms: Lyt-4, Ly-5, T200, CD45, B220
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Macrod2
Name: mono-ADP ribosylhydrolase 2
Synonyms: 2610107G07Rik, 2900006F19Rik, 1110033L15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72899
Homologene: 85987
Amtn
Name: amelotin
Synonyms: 5430427O21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71421
Homologene: 52640
Htt
Name: huntingtin
Synonyms: C430023I11Rik, Hdh, htt, huntingtin, HD, IT15
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Nepro
Name: nucleolus and neural progenitor protein
Synonyms: BC027231
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212547
Homologene: 9127
Stk38
Name: serine/threonine kinase 38
Synonyms: 5830476G13Rik, 9530097A09Rik, Ndr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106504
Homologene: 56033
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: LOC381127, C230079D11Rik, D930044O18Rik, D430002O22Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211961
Homologene: 19371
Podn
Name: podocan
Synonyms: SLRR5A
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242608
Homologene: 17803
Cdh6
Name: cadherin 6
Synonyms: K-cadherin, cad6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12563
VEGA: 15
HGNC: HGNC:1765
Homologene: 21027
Bik
Name: BCL2-interacting killer
Synonyms: Nbk, Biklk, Blk
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12124
VEGA: 15
HGNC: HGNC:1051
Homologene: 924
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Gpn1
Name: GPN-loop GTPase 1
Synonyms: Xab1, 2410004J02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74254
Homologene: 5257
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: 2410089E03Rik, Jbts17, Hug, b2b012Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73692
Homologene: 11315
Atp7b
Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: WND, Wilson protein, Atp7a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11979
HGNC: HGNC:870
Homologene: 20063
Gbgt1
Name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227671
Homologene: 110677
Scn9a
Name: sodium channel, voltage-gated, type IX, alpha
Synonyms: PN1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20274
Homologene: 2237
Ccdc168
Name: coiled-coil domain containing 168
Synonyms: Gm8251
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Tmco6
Name: transmembrane and coiled-coil domains 6
Synonyms: 2410015B03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71983
VEGA: 18
Homologene: 12431
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 628444
Homologene: 129683
Cd101
Name: CD101 antigen
Synonyms: Igsf2, LOC381460
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Arfgef3
Name: ARFGEF family member 3
Synonyms: BIG3, D10Bwg1379e, B930094H20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: Adp, Mdga2, Mamdc1, 6720489L24Rik, 9330209L04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320772
Homologene: 45659
Trim40
Name: tripartite motif-containing 40
Synonyms: LOC240093, LOC195359, LOC333872
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 195359
Homologene: 34709
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cchra1, Cav2.3, alpha1E
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
4930503B20Rik
Name: RIKEN cDNA 4930503B20 gene
Type: Gene
Species: Mouse
Chromosome: 3
Homologene: 41344
Ccnj
Name: cyclin J
Synonyms: D430039C20Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240665
Homologene: 10413
Reg2
Name: regenerating islet-derived 2
Synonyms: pancreatic thread protein
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19693
Homologene: 68517
Or52d3
Name: olfactory receptor family 52 subfamily D member 3
Synonyms: Olfr653, MOR33-1, GA_x6K02T2PBJ9-7206970-7207923
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57250
Homologene: 115518
Epx
Name: eosinophil peroxidase
Synonyms: EPO
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13861
HGNC: HGNC:3423
Homologene: 20144
Neil3
Name: nei like 3 (E. coli)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234258
Homologene: 10094
Kcnj13
Name: potassium inwardly-rectifying channel, subfamily J, member 13
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100040591
HGNC: HGNC:6259
Homologene: 55638
Decr1
Name: 2,4-dienoyl CoA reductase 1, mitochondrial
Synonyms: Decr, Nadph, 1200012F07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67460
HGNC: HGNC:2753
Homologene: 68178
Rpe65
Name: retinal pigment epithelium 65
Synonyms: rd12, A930029L06Rik, Mord1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19892
Homologene: 20108
Zswim2
Name: zinc finger SWIM-type containing 2
Synonyms: 4933437F18Rik, 1700025P14Rik, MEX
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71861
Homologene: 32689
Snai3
Name: snail family zinc finger 3
Synonyms: Zfp293, Snail-related gene from muscle cells, Smuc
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 30927
Homologene: 8500
Zfp84
Name: zinc finger protein 84
Synonyms: KRAB18, Zfp69, 4633401C23Rik, 2210410P13Rik, C86188
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74352
Homologene: 51858
Slc25a23
Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Synonyms: 2310067G05Rik, SCaMC-3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66972
Homologene: 11467
Tollip
Name: toll interacting protein
Synonyms: 4931428G15Rik, 4930403G24Rik, Toll interacting protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54473
Homologene: 10375
C1qtnf7
Name: C1q and tumor necrosis factor related protein 7
Synonyms: 8430425G24Rik, CTRP7, 5530401N20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 109323
Homologene: 12900
Ubald1
Name: UBA-like domain containing 1
Synonyms: Fam100a, 1500031H01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207740
Homologene: 17055
Wfdc3
Name: WAP four-disulfide core domain 3
Synonyms: 1700127F16Rik, 1700015L13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71856
Homologene: 122221
Mroh9
Name: maestro heat-like repeat family member 9
Synonyms: Armc11, 4921528O07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78258
Homologene: 123521
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 44,056,730 bp
  • T to C, chromosome 1 at 87,387,023 bp
  • A to T, chromosome 1 at 138,072,255 bp
  • A to G, chromosome 1 at 154,413,974 bp
  • A to G, chromosome 1 at 163,076,366 bp
  • A to G, chromosome 2 at 28,505,208 bp
  • T to C, chromosome 2 at 66,568,029 bp
  • T to A, chromosome 2 at 83,939,684 bp
  • T to A, chromosome 2 at 140,452,682 bp
  • C to T, chromosome 2 at 164,734,258 bp
  • T to A, chromosome 3 at 38,981,817 bp
  • T to C, chromosome 3 at 83,045,025 bp
  • T to C, chromosome 3 at 100,993,696 bp
  • T to C, chromosome 3 at 146,650,961 bp
  • T to C, chromosome 3 at 159,614,168 bp
  • T to C, chromosome 4 at 15,924,355 bp
  • T to C, chromosome 4 at 108,021,417 bp
  • A to T, chromosome 5 at 14,681,099 bp
  • T to A, chromosome 5 at 31,507,488 bp
  • T to A, chromosome 5 at 34,834,326 bp
  • A to T, chromosome 5 at 43,609,094 bp
  • T to A, chromosome 5 at 44,541,857 bp
  • T to C, chromosome 5 at 88,378,097 bp
  • A to G, chromosome 6 at 78,407,642 bp
  • A to T, chromosome 6 at 146,766,771 bp
  • A to G, chromosome 7 at 29,776,486 bp
  • A to T, chromosome 7 at 42,043,747 bp
  • T to A, chromosome 7 at 104,580,240 bp
  • A to T, chromosome 7 at 141,898,714 bp
  • A to T, chromosome 8 at 22,022,365 bp
  • G to T, chromosome 8 at 53,599,479 bp
  • A to G, chromosome 8 at 122,456,473 bp
  • A to C, chromosome 10 at 18,664,889 bp
  • T to A, chromosome 10 at 45,097,501 bp
  • A to G, chromosome 11 at 87,868,626 bp
  • A to T, chromosome 11 at 103,376,889 bp
  • G to A, chromosome 12 at 66,723,001 bp
  • G to A, chromosome 14 at 121,622,918 bp
  • T to C, chromosome 15 at 8,176,184 bp
  • C to A, chromosome 15 at 13,044,774 bp
  • T to A, chromosome 15 at 83,544,208 bp
  • A to G, chromosome 15 at 95,894,461 bp
  • T to C, chromosome 16 at 4,879,720 bp
  • A to G, chromosome 16 at 44,731,357 bp
  • C to T, chromosome 16 at 97,951,961 bp
  • A to G, chromosome 17 at 29,000,007 bp
  • T to C, chromosome 17 at 36,888,850 bp
  • G to A, chromosome 17 at 57,053,804 bp
  • T to A, chromosome 17 at 74,856,555 bp
  • C to T, chromosome 18 at 22,525,388 bp
  • T to A, chromosome 18 at 36,738,353 bp
  • C to T, chromosome 18 at 49,921,024 bp
  • A to G, chromosome 19 at 40,845,192 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6830 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044940-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.