Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR6964Btlr/Mmmh
Stock Number:
045074-MU
Citation ID:
RRID:MMRRC_045074-MU
Other Names:
R6964 (G1)
Major Collection:

Strain Information

Gfap
Name: glial fibrillary acidic protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14580
HGNC: HGNC:4235
Homologene: 1554
Dclre1c
Name: DNA cross-link repair 1C
Synonyms: 9930121L06Rik, Artemis, Art
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227525
Homologene: 32547
Tacr3
Name: tachykinin receptor 3
Synonyms: neuromedin K receptor, Tac3r, Nk3r
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 21338
Homologene: 824
Paip1
Name: polyadenylate binding protein-interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218693
Homologene: 4709
Ambra1
Name: autophagy/beclin 1 regulator 1
Synonyms: 2310079H06Rik, D030051N19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228361
Homologene: 18204
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: eIF3-p48, eIF3-p46, Int6, 48kDa, Eif3s6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Bcl7a
Name: B cell CLL/lymphoma 7A
Synonyms: 4432415N06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77045
HGNC: HGNC:1004
Homologene: 10869
Fermt2
Name: fermitin family member 2
Synonyms: Mig2, Kindlin-2, Plekhc1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218952
Homologene: 4976
Cntrob
Name: centrobin, centrosomal BRCA2 interacting protein
Synonyms: Lip8, 9830165K03Rik, Nip2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216846
Homologene: 14205
Ntng2
Name: netrin G2
Synonyms: Lmnt2, 2610016D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 171171
Homologene: 13053
Tmem131
Name: transmembrane protein 131
Synonyms: CC28, 2610524E03Rik, YR-23, D1Bwg0491e, Neg, Rw1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56030
Homologene: 32428
A630089N07Rik
Name: RIKEN cDNA A630089N07 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320586
VEGA: 16
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 6720426B09Rik, 5930437A14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77739
Homologene: 64642
Pianp
Name: PILR alpha associated neural protein
Synonyms: C530028O21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319352
Homologene: 17799
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Tom1
Name: target of myb1 trafficking protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21968
Homologene: 88453
Stau2
Name: staufen double-stranded RNA binding protein 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 29819
Homologene: 8666
Frmd4b
Name: FERM domain containing 4B
Synonyms: 6030440G05Rik, GRSP1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232288
Homologene: 14916
Zfp287
Name: zinc finger protein 287
Synonyms: SKAT-2, B230333C16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170740
Homologene: 23244
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Wdr95
Name: WD40 repeat domain 95
Synonyms: 4930434E21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381693
Homologene: 124480
Snx13
Name: sorting nexin 13
Synonyms: RGS-PX1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217463
VEGA: 12
Homologene: 41011
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Dock10
Name: dedicator of cytokinesis 10
Synonyms: Jr5, Jr4, ZIZ3, 9330153B10Rik, A630054M16Rik, Zizimin3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210293
Homologene: 45952
Treml4
Name: triggering receptor expressed on myeloid cells-like 4
Synonyms: 5031403H21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224840
Fscn1
Name: fascin actin-bundling protein 1
Synonyms: Fan1, fascin-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14086
Homologene: 48164
Or4a72
Name: olfactory receptor family 4 subfamily A member 72
Synonyms: GA_x6K02T2Q125-51020951-51020028, MOR231-12, Olfr1245
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258784
Homologene: 121560
Haus5
Name: HAUS augmin-like complex, subunit 5
Synonyms: 2310022K01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71909
Homologene: 18969
Ptprn
Name: protein tyrosine phosphatase receptor type N
Synonyms: IA-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19275
HGNC: HGNC:9676
Homologene: 48142
Zc3h7a
Name: zinc finger CCCH type containing 7 A
Synonyms: A430104C18Rik, Zc3h7
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106205
Homologene: 8563
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234915
VEGA: 9
Homologene: 28313
Wipi1
Name: WD repeat domain, phosphoinositide interacting 1
Synonyms: 4930533H01Rik, D11Ertd498e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 52639
Homologene: 117983
Mak
Name: male germ cell-associated kinase
Synonyms: A930010O05Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17152
VEGA: 13
HGNC: HGNC:6816
Homologene: 31344
Gjc3
Name: gap junction protein, gamma 3
Synonyms: connexin 29, Cx29, Gje1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 118446
Homologene: 15399
Rhoj
Name: ras homolog family member J
Synonyms: TCL, 1110005O19Rik, TC10L, Arhj
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 80837
HGNC: HGNC:688
Homologene: 56894
Or5b118
Name: olfactory receptor family 5 subfamily B member 118
Synonyms: GA_x6K02T2RE5P-3803583-3804527, MOR202-26P, MOR202-42, Olfr1474
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258123
Homologene: 79417
Cadps2
Name: Ca2+-dependent activator protein for secretion 2
Synonyms: cpd2, A230044C21Rik, Caps2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320405
Homologene: 23060
Abcc2
Name: ATP-binding cassette, sub-family member 2
Synonyms: multidrug resistance protein 2, Mrp2, Cmoat
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Or5p53
Name: olfactory receptor family 5 subfamily P member 53
Synonyms: GA_x6K02T2PBJ9-10262759-10263691, MOR204-4, Olfr473
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258771
Homologene: 74116
Ap1g2
Name: adaptor protein complex AP-1, gamma 2 subunit
Synonyms: gamma 2-adaptin, Adtg2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11766
HGNC: HGNC:556
Homologene: 49141
Or10ag60
Name: olfactory receptor family 10 subfamily AG member 60
Synonyms: GA_x6K02T2Q125-49112575-49113519, MOR264-4, Olfr1130
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258835
Homologene: 133705
Rigi
Name: RNA sensor RIG-I
Synonyms: 6430573D20Rik, RIG-I, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, Ddx58
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230073
Homologene: 32215
Steap4
Name: STEAP family member 4
Synonyms: Tiarp, Tnfaip9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117167
Homologene: 36422
Adamts17
Name: ADAM metallopeptidase with thrombospondin type 1 motif 17
Synonyms: AU023434
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233332
Homologene: 16373
Donson
Name: downstream neighbor of SON
Synonyms: Donson, 1110025J21Rik, ORF60
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 60364
HGNC: HGNC:2993
Homologene: 32350
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
Mcat
Name: malonyl CoA:ACP acyltransferase (mitochondrial)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223722
VEGA: 15
Homologene: 15511
Rhcg
Name: Rhesus blood group-associated C glycoprotein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56315
Homologene: 32310
Fam47e
Name: family with sequence similarity 47, member E
Synonyms: LOC384198, Gm1381
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384198
Homologene: 129958
Meltf
Name: melanotransferrin
Synonyms: MTf, CD228, melanotransferrin, Mfi2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 30060
VEGA: 16
HGNC: HGNC:7037
Homologene: 4335
Tmem106b
Name: transmembrane protein 106B
Synonyms: 6430519M21Rik, 5830455K21Rik, 2310036D22Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71900
Homologene: 56806
C4bp
Name: complement component 4 binding protein
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12269
HGNC: HGNC:1325
Star
Name: steroidogenic acute regulatory protein
Synonyms: D8Ertd419e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20845
Homologene: 297
Zfp606
Name: zinc finger protein 606
Synonyms: 2410022M24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67370
Homologene: 23514
Chst11
Name: carbohydrate sulfotransferase 11
Synonyms: C4ST-1, C4ST1, C4ST, chondroitin 4, 1110020P09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 58250
Homologene: 56808
Gm10645
Name: predicted gene 10645
Type: Gene
Species: Mouse
Chromosome: 8
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 16,390,005 bp
  • T to C, chromosome 1 at 36,796,292 bp
  • T to C, chromosome 1 at 75,260,649 bp
  • T to A, chromosome 1 at 80,503,648 bp
  • A to T, chromosome 1 at 130,657,272 bp
  • T to C, chromosome 2 at 3,453,169 bp
  • T to A, chromosome 2 at 29,197,029 bp
  • T to C, chromosome 2 at 76,714,113 bp
  • T to C, chromosome 2 at 87,607,613 bp
  • T to A, chromosome 2 at 89,574,989 bp
  • C to T, chromosome 2 at 91,917,416 bp
  • T to A, chromosome 2 at 181,230,428 bp
  • T to C, chromosome 3 at 134,829,739 bp
  • A to G, chromosome 4 at 40,225,697 bp
  • A to G, chromosome 4 at 86,156,854 bp
  • A to G, chromosome 5 at 7,975,568 bp
  • A to T, chromosome 5 at 92,566,052 bp
  • T to C, chromosome 5 at 123,369,456 bp
  • C to T, chromosome 5 at 137,957,497 bp
  • C to T, chromosome 5 at 142,960,660 bp
  • T to G, chromosome 5 at 149,581,850 bp
  • C to T, chromosome 6 at 13,082,423 bp
  • A to C, chromosome 6 at 23,583,459 bp
  • A to G, chromosome 6 at 47,516,509 bp
  • C to T, chromosome 6 at 97,305,197 bp
  • T to A, chromosome 6 at 124,999,390 bp
  • T to A, chromosome 7 at 12,489,592 bp
  • G to A, chromosome 7 at 30,657,615 bp
  • T to A, chromosome 7 at 66,909,400 bp
  • A to G, chromosome 7 at 67,004,353 bp
  • A to G, chromosome 7 at 79,600,531 bp
  • A to T, chromosome 7 at 107,933,759 bp
  • A to G, chromosome 7 at 142,439,421 bp
  • T to A, chromosome 8 at 25,811,823 bp
  • T to G, chromosome 8 at 45,043,945 bp
  • G to A, chromosome 8 at 75,051,965 bp
  • C to T, chromosome 8 at 83,165,952 bp
  • A to G, chromosome 8 at 104,543,581 bp
  • G to C, chromosome 9 at 8,112,100 bp
  • C to T, chromosome 10 at 83,191,381 bp
  • A to T, chromosome 11 at 62,724,817 bp
  • G to A, chromosome 11 at 69,309,491 bp
  • G to A, chromosome 11 at 102,896,957 bp
  • C to T, chromosome 11 at 109,603,764 bp
  • A to C, chromosome 12 at 35,119,789 bp
  • T to A, chromosome 12 at 75,375,389 bp
  • T to C, chromosome 12 at 81,773,003 bp
  • T to A, chromosome 13 at 41,032,591 bp
  • C to T, chromosome 13 at 119,450,770 bp
  • A to T, chromosome 14 at 45,465,142 bp
  • A to T, chromosome 14 at 55,099,265 bp
  • G to A, chromosome 15 at 43,272,289 bp
  • A to G, chromosome 15 at 83,547,931 bp
  • G to A, chromosome 16 at 11,149,224 bp
  • A to G, chromosome 16 at 31,880,162 bp
  • A to G, chromosome 16 at 91,681,219 bp
  • A to T, chromosome 16 at 98,065,759 bp
  • G to T, chromosome 17 at 48,272,819 bp
  • T to A, chromosome 19 at 13,471,361 bp
  • A to C, chromosome 19 at 43,798,076 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6964 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045074-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.