Strain Name:
C57BL/6J-MtgxR7002Btlr/Mmmh
Stock Number:
045107-MU
Citation ID:
RRID:MMRRC_045107-MU
Other Names:
R7002 (G1)
Major Collection:

Strain Information

Igfbp2
Name: insulin-like growth factor binding protein 2
Synonyms: Igfbp-2, IGFBP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16008
HGNC: HGNC:5471
Homologene: 499
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Nup188
Name: nucleoporin 188
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227699
Homologene: 45683
Col18a1
Name: collagen, type XVIII, alpha 1
Synonyms: endostatin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12822
HGNC: HGNC:2195
Homologene: 7673
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: mXrn1, Dhm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24127
Homologene: 5894
Abl2
Name: ABL proto-oncogene 2, non-receptor tyrosine kinase
Synonyms: Arg, Abll
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11352
HGNC: HGNC:77
Homologene: 5278
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: Listerin, Rnf160, Zfp294, 4930528H02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Dip2b
Name: disco interacting protein 2 homolog B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239667
Homologene: 72227
Gan
Name: giant axonal neuropathy
Synonyms: gigaxonin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 209239
HGNC: HGNC:4137
Homologene: 32523
Hdac4
Name: histone deacetylase 4
Synonyms: 4932408F19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208727
Homologene: 55946
Gpatch2l
Name: G patch domain containing 2 like
Synonyms: 1700020O03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70373
VEGA: 12
Homologene: 9942
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: E230037B21Rik, p193, Adprtl1, VAULT3, C030027K23Rik, PH5P, VPARP
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Immt
Name: inner membrane protein, mitochondrial
Synonyms: P87, 1700082C19Rik, D830041H16Rik, P89, P87/89, mitofilin, HMP, Micos60
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 76614
HGNC: HGNC:6047
Homologene: 38234
Mnat1
Name: menage a trois 1
Synonyms: E130115E11Rik, MAT1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 17420
HGNC: HGNC:7181
Homologene: 1821
Pals2
Name: protein associated with LIN7 2, MAGUK family member
Synonyms: Mpp6, P55t, Pals2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56524
Homologene: 22976
Lrrfip1
Name: leucine rich repeat (in FLII) interacting protein 1
Synonyms: FLAP (FLI LRR associated protein), Fliiap1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16978
HGNC: HGNC:6702
Homologene: 48301
Smc5
Name: structural maintenance of chromosomes 5
Synonyms: Smc5l1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226026
VEGA: 19
Homologene: 41009
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Vps11
Name: VPS11, CORVET/HOPS core subunit
Synonyms: 1200011A11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71732
VEGA: 9
Homologene: 6673
Syt2
Name: synaptotagmin II
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20980
Homologene: 22516
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Rnf13
Name: ring finger protein 13
Synonyms: Rzf, 2010001H16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 24017
Homologene: 13493
Zmynd11
Name: zinc finger, MYND domain containing 11
Synonyms: 2210402G22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66505
Homologene: 4828
Pbrm1
Name: polybromo 1
Synonyms: BAF180, Pb1, 2310032M22Rik, 2610016F04Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66923
Homologene: 10044
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 329002
Homologene: 7198
Garnl3
Name: GTPase activating RANGAP domain-like 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99326
Homologene: 13003
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Ip3r3, Itpr-3, tf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL19, LOC380889, Dnahc7l, DLP12, Dnahc12, 4921531P07Rik, DHC3, HL-19
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Dnase1
Name: deoxyribonuclease I
Synonyms: Dnl1, DNaseI
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13419
HGNC: HGNC:2956
Homologene: 3826
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Irs1
Name: insulin receptor substrate 1
Synonyms: IRS-1, G972R
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16367
HGNC: HGNC:6125
Homologene: 4049
Vmn1r50
Name: vomeronasal 1 receptor 50
Synonyms: VN2, V1rb1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113852
Homologene: 113975
Gjd4
Name: gap junction protein, delta 4
Synonyms: 9430022F06Rik, connexin 39, Cx39
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225152
VEGA: 18
Homologene: 17692
Duox1
Name: dual oxidase 1
Synonyms: LNOX1, 9930101G15Rik, THOX1, NOXEF1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Or5b120
Name: olfactory receptor family 5 subfamily B member 120
Synonyms: Olfr1477, GA_x6K02T2RE5P-3834960-3835907, MOR202-10
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258691
Homologene: 110492
Mprip
Name: myosin phosphatase Rho interacting protein
Synonyms: Rhoip3, Gm34094, p116 Rho interacting protein, RIP3, p116Rip
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26936
Homologene: 9034
Grhpr
Name: glyoxylate reductase/hydroxypyruvate reductase
Synonyms: 6430629L09Rik, 1110059D05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76238
HGNC: HGNC:4570
Homologene: 49088
Abca8b
Name: ATP-binding cassette, sub-family A member 8b
Synonyms: Abca8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Crybg1
Name: crystallin beta-gamma domain containing 1
Synonyms: Aim1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11630
HGNC: HGNC:356
Homologene: 18168
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 666060
Homologene: 8939
Gid8
Name: GID complex subunit 8
Synonyms: 2310003C23Rik, 4833420G11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76425
Homologene: 41207
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: Abp1, 1600012D06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mar, Mor1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Speg
Name: SPEG complex locus
Synonyms: SPEGalpha, SPEG, D1Bwg1450e, Apeg1, SPEGbeta, BPEG
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11790
Homologene: 55619
Mmut
Name: methylmalonyl-Coenzyme A mutase
Synonyms: Mut, D230010K02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17850
VEGA: 17
HGNC: HGNC:7526
Homologene: 20097
Adamts18
Name: ADAM metallopeptidase with thrombospondin type 1 motif 18
Synonyms: E130314N14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 208936
Homologene: 65241
Or8k40
Name: olfactory receptor family 8 subfamily K member 40
Synonyms: Olfr1090, GA_x6K02T2Q125-48247345-48246404, MOR188-4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258844
Homologene: 17413
Dab2
Name: disabled 2, mitogen-responsive phosphoprotein
Synonyms: 5730435J12Rik, D15Wsu122e, D630005B22Rik, p96
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13132
HGNC: HGNC:2662
Homologene: 1026
Sec14l3
Name: SEC14-like lipid binding 3
Synonyms: 1110069O07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380683
Homologene: 24848
Adam6b
Name: a disintegrin and metallopeptidase domain 6B
Synonyms: 4930523C11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238405
Homologene: 128362
Tchp
Name: trichoplein, keratin filament binding
Synonyms: A930031F18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77832
Homologene: 12686
Prss40
Name: serine protease 40
Synonyms: Tesp2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21756
Homologene: 69043
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: 1200002D17Rik, TSC403, DC-LAMP, Cd208
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239739
VEGA: 16
Homologene: 8670
Erich5
Name: glutamate rich 5
Synonyms: BC030476
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239368
VEGA: 15
Homologene: 52129
Cerk
Name: ceramide kinase
Synonyms: D330016D08Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223753
Homologene: 11247
Apol10a
Name: apolipoprotein L 10A
Synonyms: 9030421J09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 245282
Homologene: 129975
Zfp316
Name: zinc finger protein 316
Synonyms: Emzf1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54201
Homologene: 69231
Bend4
Name: BEN domain containing 4
Synonyms: D330027G24Rik, EG666938
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 666938
Homologene: 52626
Eef2k
Name: eukaryotic elongation factor-2 kinase
Synonyms: eEF-2K
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13631
Homologene: 7299
Serpina1e
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1E
Synonyms: PI5, Spi1-5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20704
HGNC: HGNC:8941
Homologene: 20103
Il18r1
Name: interleukin 18 receptor 1
Synonyms: Il1rrp, Il18ralpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16182
HGNC: HGNC:5988
Homologene: 2861
Senp5
Name: SUMO/sentrin specific peptidase 5
Synonyms: 6230429P13Rik, A730063F07Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320213
Homologene: 17647
Nfu1
Name: NFU1 iron-sulfur cluster scaffold
Synonyms: 0610006G17Rik, Hirip5, CGI-33
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56748
Homologene: 6369
H2bc21
Name: H2B clustered histone 21
Synonyms: Hist2h2be
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 319190
HGNC: HGNC:4761
Homologene: 128594
Sepsecs
Name: Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Synonyms: D5Ertd135e, SecS, SLA
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 211006
Homologene: 15031
Jrkl
Name: Jrk-like
Synonyms: C030035D04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77532
VEGA: 9
HGNC: HGNC:6200
Homologene: 2797
Cplx1
Name: complexin 1
Synonyms: 921-S
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12889
HGNC: HGNC:2309
Homologene: 21324
Cwc25
Name: CWC25 spliceosome-associated protein
Synonyms: 1300013D05Rik, Ccdc49, R75228
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67480
Homologene: 135922
Slc35f3
Name: solute carrier family 35, member F3
Synonyms: B230375D17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210027
Homologene: 62481
Trim12a
Name: tripartite motif-containing 12A
Synonyms: 2310043C01Rik, Trim12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76681
Slc10a4-ps
Name: solute carrier family 10 (sodium/bile acid cotransporter family), pseudogene
Synonyms: Slc10a4l, Gm5868
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 545758
Igkv4-61
Name: immunoglobulin kappa chain variable 4-61
Synonyms: Gm16895
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 546244
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 34,552,400 bp
  • G to A, chromosome 1 at 40,474,853 bp
  • C to T, chromosome 1 at 72,849,645 bp
  • T to A, chromosome 1 at 75,423,268 bp
  • T to C, chromosome 1 at 82,288,260 bp
  • T to A, chromosome 1 at 91,115,458 bp
  • T to G, chromosome 1 at 91,968,361 bp
  • T to A, chromosome 1 at 134,744,104 bp
  • A to T, chromosome 1 at 156,559,133 bp
  • T to A, chromosome 2 at 30,323,568 bp
  • T to A, chromosome 2 at 33,054,193 bp
  • T to C, chromosome 2 at 76,798,217 bp
  • T to A, chromosome 2 at 82,989,343 bp
  • T to C, chromosome 2 at 86,754,681 bp
  • C to T, chromosome 2 at 122,319,877 bp
  • T to G, chromosome 2 at 180,713,303 bp
  • A to G, chromosome 3 at 57,833,612 bp
  • A to G, chromosome 3 at 96,221,373 bp
  • T to C, chromosome 4 at 44,990,427 bp
  • C to T, chromosome 4 at 45,284,200 bp
  • G to A, chromosome 5 at 32,877,158 bp
  • T to C, chromosome 5 at 52,647,208 bp
  • T to A, chromosome 5 at 67,398,259 bp
  • T to A, chromosome 5 at 72,586,420 bp
  • T to A, chromosome 5 at 108,520,316 bp
  • C to T, chromosome 5 at 114,708,796 bp
  • T to C, chromosome 5 at 143,263,355 bp
  • T to C, chromosome 5 at 150,539,918 bp
  • A to G, chromosome 6 at 48,905,876 bp
  • C to T, chromosome 6 at 50,162,662 bp
  • T to G, chromosome 6 at 69,417,389 bp
  • T to C, chromosome 6 at 71,861,040 bp
  • C to A, chromosome 6 at 87,016,272 bp
  • T to A, chromosome 6 at 90,107,837 bp
  • C to T, chromosome 7 at 25,272,196 bp
  • T to C, chromosome 7 at 80,469,753 bp
  • A to G, chromosome 7 at 104,304,176 bp
  • G to A, chromosome 7 at 120,891,932 bp
  • T to A, chromosome 8 at 113,775,290 bp
  • T to C, chromosome 8 at 117,195,847 bp
  • CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC to CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC, chromosome 8 at 126,389,034 bp
  • A to T, chromosome 9 at 13,245,521 bp
  • G to A, chromosome 9 at 44,355,079 bp
  • C to T, chromosome 9 at 96,047,790 bp
  • T to A, chromosome 10 at 43,998,835 bp
  • A to T, chromosome 10 at 77,166,343 bp
  • A to T, chromosome 11 at 4,075,263 bp
  • A to C, chromosome 11 at 59,761,190 bp
  • A to T, chromosome 11 at 97,748,071 bp
  • A to G, chromosome 11 at 109,941,564 bp
  • T to C, chromosome 12 at 73,230,705 bp
  • G to A, chromosome 12 at 86,244,184 bp
  • T to C, chromosome 12 at 103,948,079 bp
  • T to A, chromosome 12 at 109,593,947 bp
  • C to A, chromosome 12 at 113,489,707 bp
  • A to G, chromosome 13 at 9,694,330 bp
  • T to C, chromosome 14 at 26,876,998 bp
  • T to A, chromosome 14 at 31,064,820 bp
  • T to A, chromosome 14 at 56,602,404 bp
  • A to T, chromosome 15 at 6,435,365 bp
  • C to T, chromosome 15 at 34,471,362 bp
  • G to A, chromosome 15 at 77,484,846 bp
  • T to C, chromosome 15 at 86,156,594 bp
  • T to A, chromosome 15 at 100,160,465 bp
  • A to G, chromosome 16 at 4,039,546 bp
  • G to T, chromosome 16 at 19,655,422 bp
  • A to G, chromosome 16 at 31,983,775 bp
  • A to T, chromosome 16 at 87,423,473 bp
  • T to C, chromosome 17 at 27,110,580 bp
  • T to A, chromosome 17 at 40,941,383 bp
  • C to A, chromosome 18 at 9,280,960 bp
  • A to G, chromosome 18 at 82,691,576 bp
  • A to G, chromosome 19 at 13,502,675 bp
  • A to G, chromosome 19 at 23,231,883 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7002 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045107-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.