Strain Name:
C57BL/6J-MtgxR7013Btlr/Mmmh
Stock Number:
045114-MU
Citation ID:
RRID:MMRRC_045114-MU
Other Names:
R7013 (G1)
Major Collection:

Strain Information

Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: C330012K04Rik, GalNAc-T10, Galnt9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171212
Homologene: 14924
Arid5b
Name: AT-rich interaction domain 5B
Synonyms: Desrt, 5430435G07Rik, Mrf2beta, Mrf2alpha, Mrf2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71371
VEGA: 10
Homologene: 45872
Exo1
Name: exonuclease 1
Synonyms: 5730442G03Rik, Msa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26909
HGNC: HGNC:3511
Homologene: 31352
Zfp106
Name: zinc finger protein 106
Synonyms: Cd-1, H3a, sirm, Sh3bp3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20402
Homologene: 40787
Abcc4
Name: ATP-binding cassette, sub-family C member 4
Synonyms: D630049P08Rik, MRP4, MOAT-B
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239273
VEGA: 14
HGNC: HGNC:55
Homologene: 74563
Orc5
Name: origin recognition complex, subunit 5
Synonyms: Orc5l, mouse origin recognition complex 5, MmORC5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26429
HGNC: HGNC:8491
Homologene: 37636
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Dsg4
Name: desmoglein 4
Synonyms: CDHF13, lah
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16769
Homologene: 65341
Jak3
Name: Janus kinase 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16453
HGNC: HGNC:6193
Homologene: 181
Dkk2
Name: dickkopf WNT signaling pathway inhibitor 2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56811
HGNC: HGNC:2892
Homologene: 8681
Recql5
Name: RecQ protein-like 5
Synonyms: Recq5b, Recql5b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170472
HGNC: HGNC:9950
Homologene: 31232
Il20rb
Name: interleukin 20 receptor beta
Synonyms: LOC213208, Il20R2, Fndc6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 213208
HGNC: HGNC:6004
Homologene: 86034
Crmp1
Name: collapsin response mediator protein 1
Synonyms: DRP-1, Ulip3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12933
HGNC: HGNC:2365
Homologene: 20347
Smap2
Name: small ArfGAP 2
Synonyms: Smap1l, 1810031K02Rik, Smap2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69780
Homologene: 41489
Lnpep
Name: leucyl/cystinyl aminopeptidase
Synonyms: 2010309L07Rik, vp165, IRAP, 4732490P18Rik, gp160
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240028
VEGA: 17
HGNC: HGNC:6656
Homologene: 21148
Atl1
Name: atlastin GTPase 1
Synonyms: FSP1, AD-FSP, Spg3a, SPG3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73991
VEGA: 12
Homologene: 9302
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: Dpr2, Frd2, 2900084M21Rik, dapper2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240025
VEGA: 17
Homologene: 18237
Rnf212
Name: ring finger protein 212
Synonyms: EG330157, repro57
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 671564
Homologene: 131269
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212167
Homologene: 45504
Drc3
Name: dynein regulatory complex subunit 3
Synonyms: m6Bei, 4930449E07Rik, Lrrc48
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74665
Homologene: 12581
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: A930015H12Rik, IMP150, SPACR
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Nlrp1a
Name: NLR family, pyrin domain containing 1A
Synonyms: Nalp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195046
Homologene: 133820
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: vp115, Mbc2, Fam62a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23943
VEGA: 10
Homologene: 40794
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190-B, p190B
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Syt11
Name: synaptotagmin XI
Synonyms: 6530420C11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229521
Homologene: 23120
Adhfe1
Name: alcohol dehydrogenase, iron containing, 1
Synonyms: 6330565B14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76187
Homologene: 5865
Fam20b
Name: FAM20B, glycosaminoglycan xylosylkinase
Synonyms: C530043G21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215015
Homologene: 8909
Ces1c
Name: carboxylesterase 1C
Synonyms: Es-1, Es-N, Es-4, Ee-1, Ces-N, Es1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13884
HGNC: HGNC:1863
Homologene: 117484
Lman2l
Name: lectin, mannose-binding 2-like
Synonyms: A630028F14Rik, VIP36-like
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214895
Homologene: 57125
Bank1
Name: B cell scaffold protein with ankyrin repeats 1
Synonyms: A530094C12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242248
Homologene: 9926
Or4f15
Name: olfactory receptor family 4 subfamily F member 15
Synonyms: MOR245-5, Olfr1309, GA_x6K02T2Q125-73031456-73030518
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258439
Homologene: 74054
Ptprr
Name: protein tyrosine phosphatase receptor type R
Synonyms: PTPBR7, RPTPRR, PTP-SL
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19279
HGNC: HGNC:9680
Homologene: 2135
Ttbk2
Name: tau tubulin kinase 2
Synonyms: 2610507N02Rik, B930008N24Rik, TTK
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 140810
Homologene: 62795
Or1e23
Name: olfactory receptor family 1 subfamily E member 23
Synonyms: MOR135-14, MOR135-31_p, Olfr382, GA_x6K02T2P1NL-3676608-3675670
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258435
Homologene: 17252
Vmn1r66
Name: vomeronasal 1 receptor 66
Synonyms: V1re11
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171264
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227157
Homologene: 23296
Rsph6a
Name: radial spoke head 6 homolog A (Chlamydomonas)
Synonyms: Rshl1, RSP4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83434
Homologene: 36476
Pate8
Name: prostate and testis expressed 8
Synonyms: Gm17689
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100312948
Tmprss11d
Name: transmembrane protease, serine 11d
Synonyms: AsP
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231382
Homologene: 74519
Or4n4b
Name: olfactory receptor family 4 subfamily N member 4B
Synonyms: GA_x6K02T2PMLR-5992342-5991416, Olfr733, MOR241-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258657
Homologene: 128266
Csnka2ip
Name: casein kinase 2, alpha prime interacting protein
Synonyms: Ckt2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224291
Homologene: 77570
Or4b13
Name: olfactory receptor family 4 subfamily B member 13
Synonyms: Olfr142, K20, GA_x6K02T2Q125-51607674-51606757, MOR227-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 406186
HGNC: HGNC:8290
Homologene: 45081
Vmn1r119
Name: vomeronasal 1 receptor 119
Synonyms: LOC384696, Gm1447
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384696
Homologene: 104166
Fmo6
Name: flavin containing monooxygenase 6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226565
Homologene: 68130
Terb1
Name: telomere repeat binding bouquet formation protein 1
Synonyms: 4930532D21Rik, Ccdc79
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320022
Homologene: 18330
Or4a79
Name: olfactory receptor family 4 subfamily A member 79
Synonyms: Olfr1252, MOR231-22_p, GA_x6K02T2Q125-51162884-51161940
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404331
Homologene: 128094
Lbhd1
Name: LBH domain containing 1
Synonyms: Gm21743
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 102308570
Homologene: 75203
Pcdhga3
Name: protocadherin gamma subfamily A, 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93711
HGNC: HGNC:8701
Homologene: 75100
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 9,550,591 bp
  • A to G, chromosome 1 at 36,443,518 bp
  • T to C, chromosome 1 at 59,149,615 bp
  • A to G, chromosome 1 at 156,690,565 bp
  • G to A, chromosome 1 at 162,918,248 bp
  • G to T, chromosome 1 at 175,893,772 bp
  • T to A, chromosome 2 at 89,721,386 bp
  • C to T, chromosome 2 at 90,252,097 bp
  • G to A, chromosome 2 at 111,983,963 bp
  • T to C, chromosome 2 at 120,531,632 bp
  • T to C, chromosome 2 at 120,745,784 bp
  • A to T, chromosome 3 at 88,747,989 bp
  • T to C, chromosome 3 at 132,174,999 bp
  • A to G, chromosome 3 at 136,100,509 bp
  • T to C, chromosome 4 at 120,982,168 bp
  • A to T, chromosome 5 at 21,278,110 bp
  • A to G, chromosome 5 at 22,533,789 bp
  • A to T, chromosome 5 at 37,268,692 bp
  • C to A, chromosome 5 at 86,326,573 bp
  • A to T, chromosome 5 at 108,729,960 bp
  • C to T, chromosome 6 at 84,137,358 bp
  • A to G, chromosome 6 at 121,641,386 bp
  • T to C, chromosome 7 at 10,274,756 bp
  • A to G, chromosome 7 at 19,054,895 bp
  • T to A, chromosome 7 at 21,011,789 bp
  • G to T, chromosome 8 at 71,678,781 bp
  • A to T, chromosome 8 at 93,130,764 bp
  • A to T, chromosome 8 at 104,488,590 bp
  • C to A, chromosome 9 at 36,582,558 bp
  • A to T, chromosome 9 at 80,378,494 bp
  • A to G, chromosome 9 at 100,461,428 bp
  • A to G, chromosome 10 at 68,097,819 bp
  • T to A, chromosome 10 at 116,236,754 bp
  • A to T, chromosome 10 at 128,525,651 bp
  • A to T, chromosome 11 at 57,765,584 bp
  • A to G, chromosome 11 at 60,387,303 bp
  • G to A, chromosome 11 at 71,123,552 bp
  • G to T, chromosome 11 at 73,516,421 bp
  • A to G, chromosome 11 at 115,894,576 bp
  • T to A, chromosome 12 at 8,010,080 bp
  • T to A, chromosome 12 at 52,518,326 bp
  • A to G, chromosome 12 at 69,953,440 bp
  • T to A, chromosome 14 at 50,299,199 bp
  • A to T, chromosome 14 at 118,526,343 bp
  • T to C, chromosome 16 at 64,478,417 bp
  • T to C, chromosome 17 at 14,203,534 bp
  • C to A, chromosome 17 at 17,568,363 bp
  • T to C, chromosome 18 at 20,458,521 bp
  • A to G, chromosome 18 at 37,675,621 bp
  • T to C, chromosome 19 at 8,884,159 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7013 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045114-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.