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Strain Name:
C57BL/6J-MtgxR7013Btlr/Mmmh
Stock Number:
045114-MU
Citation ID:
RRID:MMRRC_045114-MU
Other Names:
R7013 (G1)
Major Collection:

Strain Information

Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: GalNAc-T10, Galnt9, C330012K04Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171212
Homologene: 14924
Arid5b
Name: AT-rich interaction domain 5B
Synonyms: 5430435G07Rik, Desrt, Mrf2beta, Mrf2alpha, Mrf2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71371
VEGA: 10
Homologene: 45872
Exo1
Name: exonuclease 1
Synonyms: Msa, 5730442G03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26909
HGNC: HGNC:3511
Homologene: 31352
Zfp106
Name: zinc finger protein 106
Synonyms: Cd-1, H3a, sirm, Sh3bp3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20402
Homologene: 40787
Abcc4
Name: ATP-binding cassette, sub-family C member 4
Synonyms: D630049P08Rik, MOAT-B, MRP4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239273
VEGA: 14
HGNC: HGNC:55
Homologene: 74563
Orc5
Name: origin recognition complex, subunit 5
Synonyms: mouse origin recognition complex 5, MmORC5, Orc5l
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26429
HGNC: HGNC:8491
Homologene: 37636
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 9,550,591 bp
  • A to G, chromosome 1 at 36,443,518 bp
  • T to C, chromosome 1 at 59,149,615 bp
  • A to G, chromosome 1 at 156,690,565 bp
  • G to A, chromosome 1 at 162,918,248 bp
  • G to T, chromosome 1 at 175,893,772 bp
  • T to A, chromosome 2 at 89,721,386 bp
  • C to T, chromosome 2 at 90,252,097 bp
  • G to A, chromosome 2 at 111,983,963 bp
  • T to C, chromosome 2 at 120,531,632 bp
  • T to C, chromosome 2 at 120,745,784 bp
  • A to T, chromosome 3 at 88,747,989 bp
  • T to C, chromosome 3 at 132,174,999 bp
  • A to G, chromosome 3 at 136,100,509 bp
  • T to C, chromosome 4 at 120,982,168 bp
  • A to T, chromosome 5 at 21,278,110 bp
  • A to G, chromosome 5 at 22,533,789 bp
  • A to T, chromosome 5 at 37,268,692 bp
  • C to A, chromosome 5 at 86,326,573 bp
  • A to T, chromosome 5 at 108,729,960 bp
  • C to T, chromosome 6 at 84,137,358 bp
  • A to G, chromosome 6 at 121,641,386 bp
  • T to C, chromosome 7 at 10,274,756 bp
  • A to G, chromosome 7 at 19,054,895 bp
  • T to A, chromosome 7 at 21,011,789 bp
  • G to T, chromosome 8 at 71,678,781 bp
  • A to T, chromosome 8 at 93,130,764 bp
  • A to T, chromosome 8 at 104,488,590 bp
  • C to A, chromosome 9 at 36,582,558 bp
  • A to T, chromosome 9 at 80,378,494 bp
  • A to G, chromosome 9 at 100,461,428 bp
  • A to G, chromosome 10 at 68,097,819 bp
  • T to A, chromosome 10 at 116,236,754 bp
  • A to T, chromosome 10 at 128,525,651 bp
  • A to T, chromosome 11 at 57,765,584 bp
  • A to G, chromosome 11 at 60,387,303 bp
  • G to A, chromosome 11 at 71,123,552 bp
  • G to T, chromosome 11 at 73,516,421 bp
  • A to G, chromosome 11 at 115,894,576 bp
  • T to A, chromosome 12 at 8,010,080 bp
  • T to A, chromosome 12 at 52,518,326 bp
  • A to G, chromosome 12 at 69,953,440 bp
  • T to A, chromosome 14 at 50,299,199 bp
  • A to T, chromosome 14 at 118,526,343 bp
  • T to C, chromosome 16 at 64,478,417 bp
  • T to C, chromosome 17 at 14,203,534 bp
  • C to A, chromosome 17 at 17,568,363 bp
  • T to C, chromosome 18 at 20,458,521 bp
  • A to G, chromosome 18 at 37,675,621 bp
  • T to C, chromosome 19 at 8,884,159 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7013 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045114-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.