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Strain Name:
C57BL/6J-MtgxR7054Btlr/Mmmh
Stock Number:
045151-MU
Citation ID:
RRID:MMRRC_045151-MU
Other Names:
R7054 (G1)
Major Collection:

Strain Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: N-CoR, Rxrip13, A230020K14Rik, 5730405M06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Ank-2, Ankyrin-2, Ankyrin-B, Gm4392
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Dpy30
Name: dpy-30, histone methyltransferase complex regulatory subunit
Synonyms: 2810410M20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66310
VEGA: 17
Homologene: 32582
Ift52
Name: intraflagellar transport 52
Synonyms: NGD5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 245866
Homologene: 9335
Apod
Name: apolipoprotein D
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11815
HGNC: HGNC:612
Homologene: 1246
Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330953
VEGA: 9
Homologene: 3997
Ltbp4
Name: latent transforming growth factor beta binding protein 4
Synonyms: 2310046A13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108075
HGNC: HGNC:6717
Homologene: 2645
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: Rnf164, D930043C02Rik, 2900024N03Rik, 9430019J22Rik, Mnab
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319817
Homologene: 28276
Dot1l
Name: DOT1 like histone lysine methyltransferase
Synonyms: mDot1, KMT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208266
Homologene: 32779
Cenpp
Name: centromere protein P
Synonyms: 4921518G09Rik, 1700022C02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66336
VEGA: 13
Homologene: 23543
Zc3h13
Name: zinc finger CCCH type containing 13
Synonyms: C87618, 4930570G11Rik, 2600010B19Rik, 3110050K21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67302
VEGA: 14
Eed
Name: embryonic ectoderm development
Synonyms: l(7)5Rn, l7Rn5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13626
HGNC: HGNC:3188
Homologene: 2814
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Blmh
Name: bleomycin hydrolase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104184
HGNC: HGNC:1059
Homologene: 330
Skic3
Name: SKI3 subunit of superkiller complex
Synonyms: Ttc37
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218343
VEGA: 13
Homologene: 40966
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231214
Homologene: 18159
Ror1
Name: receptor tyrosine kinase-like orphan receptor 1
Synonyms: Ntrkr1, 2810404D04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26563
Homologene: 3675
Glb1l2
Name: galactosidase, beta 1-like 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244757
Homologene: 71790
Il22ra1
Name: interleukin 22 receptor, alpha 1
Synonyms: Il22r
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230828
Homologene: 10943
Limk2
Name: LIM domain kinase 2
Synonyms: Limk2b, Limk2a, A930024P04Rik, LIM kinase 2, whe
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16886
HGNC: HGNC:6614
Homologene: 55911
Ikbkb
Name: inhibitor of kappaB kinase beta
Synonyms: IKK-beta, IKK-2, IKK2, IKK[b], IKKbeta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16150
HGNC: HGNC:5960
Homologene: 7782
Zfp870
Name: zinc finger protein 870
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240066
VEGA: 17
Homologene: 48189
Armh4
Name: armadillo-like helical domain containing 4
Synonyms: 3632451O06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67419
Homologene: 12127
Pgk2
Name: phosphoglycerate kinase 2
Synonyms: Tcp-2, Tcp-2, Pgk-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18663
VEGA: 17
HGNC: HGNC:8898
Homologene: 57138
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212728
Homologene: 38082
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Gdpd4
Name: glycerophosphodiester phosphodiesterase domain containing 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233537
Homologene: 18606
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: LOC381663, A330009G12Rik, Sec63d1, Mer3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330149
Homologene: 87103
Nckap5
Name: NCK-associated protein 5
Synonyms: LOC380609, D130011D22Rik, E030049G20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210356
Homologene: 35542
Atxn7
Name: ataxin 7
Synonyms: ataxin-7, Sca7, A430107N12Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 246103
VEGA: 14
Homologene: 30967
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: 2810012G08Rik, B230396K10Rik, Cytsb
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432572
Homologene: 45157
Peg12
Name: paternally expressed 12
Synonyms: Frat3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27412
HGNC: HGNC:3944
Vmn2r111
Name: vomeronasal 2, receptor 111
Synonyms: EG210876
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210876
Homologene: 86604
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 545874
Homologene: 135915
Pex6
Name: peroxisomal biogenesis factor 6
Synonyms: D130055I09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224824
HGNC: HGNC:8859
Homologene: 47914
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: mlst-1, Slc21a6, Slc21a10, Oatp1b2, 7330442B20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28253
Homologene: 75119
4930553M12Rik
Name: RIKEN cDNA 4930553M12 gene
Type: Gene
Species: Mouse
Chromosome: 4
Abcc3
Name: ATP-binding cassette, sub-family C member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Vmn1r113
Name: vomeronasal 1 receptor 113
Synonyms: Gm5748
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 436135
Homologene: 104166
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212974
Homologene: 16023
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224576
Homologene: 135824
H2-Ab1
Name: histocompatibility 2, class II antigen A, beta 1
Synonyms: A beta, Abeta, H-2Ab, Ia-2, Ia2, H2-Ab, IAb, I-Ab, I-Abeta, Rmcs1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14961
Homologene: 1603
Zp1
Name: zona pellucida glycoprotein 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 22786
Homologene: 33483
Ifih1
Name: interferon induced with helicase C domain 1
Synonyms: Helicard, MDA5, MDA-5, 9130009C22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71586
Homologene: 32535
Or56a3b
Name: olfactory receptor family 56 subfamily A member 3B
Synonyms: GA_x6K02T2PBJ9-7750163-7751110, MOR40-14, Olfr681
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404318
Homologene: 81538
Mfhas1
Name: malignant fibrous histiocytoma amplified sequence 1
Synonyms: 2310066G09Rik, D8Ertd91e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52065
Homologene: 3114
Cimip3
Name: ciliary microtubule inner protein 3
Synonyms: 1700001C19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 75462
Homologene: 129540
Aspg
Name: asparaginase
Synonyms: A530050D06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104816
VEGA: 12
Homologene: 113390
Zfp977
Name: zinc finger protein 977
Synonyms: Gm7221
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637776
Rassf7
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
Synonyms: 2400009B11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66985
HGNC: HGNC:1166
Homologene: 2595
Llph
Name: LLP homolog, long-term synaptic facilitation (Aplysia)
Synonyms: 1190005P17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66225
Homologene: 81946
Creg2
Name: cellular repressor of E1A-stimulated genes 2
Synonyms: A830098L22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 263764
Homologene: 17827
Vmn1r42
Name: vomeronasal 1 receptor 42
Synonyms: V1ra6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113848
Homologene: 130651
Klk1b3
Name: kallikrein 1-related peptidase b3
Synonyms: mGk-3, Ngfg, Ngfg
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18050
Homologene: 68141
Polh
Name: polymerase (DNA directed), eta (RAD 30 related)
Synonyms: RAD30A
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 80905
VEGA: 17
HGNC: HGNC:9181
Homologene: 38189
Hoxd13
Name: homeobox D13
Synonyms: Hox-4.8, spdh
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15433
HGNC: HGNC:5136
Homologene: 20147
Mageb3
Name: MAGE family member B3
Synonyms: Smage3, Mage-rs3, Mage-ps1, Mage-b3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17147
Homologene: 137208
Gm3327
Name: predicted gene 3327
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 102635261
Homologene: 128452
Ttc9b
Name: tetratricopeptide repeat domain 9B
Synonyms: 2900074C18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73032
Homologene: 19938
Timm22
Name: translocase of inner mitochondrial membrane 22
Synonyms: 2610511O07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56322
Homologene: 32173
Lrrc26
Name: leucine rich repeat containing 26
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227618
Homologene: 16228
Fra10ac1
Name: FRA10A associated CGG repeat 1
Synonyms: 5730455O13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 70567
VEGA: 19
HGNC: HGNC:1162
Homologene: 13852
Hoxa1
Name: homeobox A1
Synonyms: ERA1, early retinoic acid, Hox-1.6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15394
HGNC: HGNC:5099
Homologene: 4032
Gm13889
Name: predicted gene 13889
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 620695
Homologene: 83963
Or10ag55-ps1
Name: olfactory receptor family 10 subfamily AG member 55, pseudogene 1
Synonyms: GA_x6K02T2Q125-48769330-48770299, MOR264-10P, MOR264-27_p, Olfr1117-ps1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258110
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 39,623,208 bp
  • T to A, chromosome 1 at 43,983,158 bp
  • A to T, chromosome 1 at 126,258,712 bp
  • T to A, chromosome 2 at 25,290,075 bp
  • A to G, chromosome 2 at 37,375,246 bp
  • T to A, chromosome 2 at 62,610,515 bp
  • A to G, chromosome 2 at 74,669,025 bp
  • T to C, chromosome 2 at 76,714,668 bp
  • T to A, chromosome 2 at 87,284,431 bp
  • A to T, chromosome 2 at 93,957,114 bp
  • A to G, chromosome 2 at 113,365,008 bp
  • A to T, chromosome 2 at 121,954,492 bp
  • G to A, chromosome 2 at 163,029,796 bp
  • A to T, chromosome 3 at 126,943,303 bp
  • T to A, chromosome 4 at 88,868,249 bp
  • A to T, chromosome 4 at 100,442,239 bp
  • G to A, chromosome 4 at 135,751,162 bp
  • C to T, chromosome 5 at 43,699,979 bp
  • T to C, chromosome 5 at 106,896,043 bp
  • A to G, chromosome 6 at 28,446,323 bp
  • A to G, chromosome 6 at 52,158,200 bp
  • T to C, chromosome 6 at 89,845,069 bp
  • T to A, chromosome 6 at 123,823,610 bp
  • A to T, chromosome 6 at 141,672,248 bp
  • A to G, chromosome 7 at 20,787,502 bp
  • A to G, chromosome 7 at 27,307,766 bp
  • A to G, chromosome 7 at 27,654,242 bp
  • A to T, chromosome 7 at 42,580,362 bp
  • A to T, chromosome 7 at 44,201,439 bp
  • T to C, chromosome 7 at 62,463,963 bp
  • A to G, chromosome 7 at 89,964,727 bp
  • T to A, chromosome 7 at 97,973,929 bp
  • T to G, chromosome 7 at 104,861,307 bp
  • C to T, chromosome 7 at 105,121,963 bp
  • G to A, chromosome 7 at 140,944,718 bp
  • T to A, chromosome 7 at 141,217,643 bp
  • A to G, chromosome 8 at 22,671,642 bp
  • T to C, chromosome 8 at 35,588,638 bp
  • T to A, chromosome 8 at 126,474,495 bp
  • A to T, chromosome 9 at 26,765,127 bp
  • T to C, chromosome 9 at 58,855,717 bp
  • A to G, chromosome 10 at 80,787,023 bp
  • A to T, chromosome 10 at 120,231,335 bp
  • T to C, chromosome 11 at 3,355,448 bp
  • T to A, chromosome 11 at 62,117,778 bp
  • T to C, chromosome 11 at 62,384,793 bp
  • A to G, chromosome 11 at 76,407,245 bp
  • G to C, chromosome 11 at 76,968,625 bp
  • T to C, chromosome 11 at 94,365,225 bp
  • T to A, chromosome 12 at 112,126,390 bp
  • T to C, chromosome 13 at 49,465,757 bp
  • G to A, chromosome 13 at 76,134,960 bp
  • A to T, chromosome 14 at 14,100,878 bp
  • T to A, chromosome 14 at 43,575,870 bp
  • T to C, chromosome 14 at 44,126,275 bp
  • C to A, chromosome 14 at 49,773,698 bp
  • T to C, chromosome 14 at 53,531,299 bp
  • T to C, chromosome 14 at 75,321,787 bp
  • G to A, chromosome 14 at 103,156,098 bp
  • A to G, chromosome 16 at 31,311,132 bp
  • A to G, chromosome 17 at 20,278,920 bp
  • T to C, chromosome 17 at 22,559,051 bp
  • T to C, chromosome 17 at 32,883,482 bp
  • T to C, chromosome 17 at 34,263,342 bp
  • T to A, chromosome 17 at 40,208,475 bp
  • A to T, chromosome 17 at 46,198,716 bp
  • G to A, chromosome 17 at 46,720,521 bp
  • A to G, chromosome 17 at 47,437,189 bp
  • A to G, chromosome 17 at 74,307,840 bp
  • G to A, chromosome 19 at 10,918,740 bp
  • C to T, chromosome 19 at 38,224,119 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7054 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045151-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.