Strain Name:
C57BL/6J-MtgxR7223Btlr/Mmmh
Stock Number:
045295-MU
Citation ID:
RRID:MMRRC_045295-MU
Other Names:
R7223 (G1)
Major Collection:

Strain Information

Sufu
Name: SUFU negative regulator of hedgehog signaling
Synonyms: Su(Fu), 2810026F04Rik, b2b273Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 24069
Homologene: 9262
Htr1d
Name: 5-hydroxytryptamine (serotonin) receptor 1D
Synonyms: Gpcr14, Htr1db
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15552
HGNC: HGNC:5289
Homologene: 20240
Jarid2
Name: jumonji and AT-rich interaction domain containing 2
Synonyms: Jmj, jumonji
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16468
HGNC: HGNC:6196
Homologene: 31279
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: 2510010B09Rik, D10Ertd17e, Cxxc6, BB001228
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52463
Homologene: 12735
Pipox
Name: pipecolic acid oxidase
Synonyms: Pso
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19193
Homologene: 40640
Tmem121
Name: transmembrane protein 121
Synonyms: Hole, 2410008J05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 69195
Homologene: 11900
Dnajc24
Name: DnaJ heat shock protein family (Hsp40) member C24
Synonyms: MmDjC7, 2610027M02Rik, 1700030A21Rik, Zcsl3, Dph4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99349
Homologene: 41704
Mybl2
Name: myeloblastosis oncogene-like 2
Synonyms: Bmyb, B-Myb
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17865
HGNC: HGNC:7548
Homologene: 1847
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103554
Homologene: 113742
Cul3
Name: cullin 3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26554
HGNC: HGNC:2553
Homologene: 2661
Daam1
Name: dishevelled associated activator of morphogenesis 1
Synonyms: 1700066F09Rik, 2310028E21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 208846
VEGA: 12
Homologene: 36635
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Tip5, Walp3, C030005G16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108989
Homologene: 37753
Cdk5rap2
Name: CDK5 regulatory subunit associated protein 2
Synonyms: 2900018K03Rik, an
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 214444
Homologene: 49533
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
N6amt1
Name: N-6 adenine-specific DNA methyltransferase 1 (putative)
Synonyms: 5830445C04Rik, Pred28, Hemk2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67768
Homologene: 5637
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: RIM2, 2810036I15Rik, Syt3-rs
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 116838
VEGA: 15
Homologene: 81639
Zic2
Name: zinc finger protein of the cerebellum 2
Synonyms: GENA 29, Ku, odd-paired homolog
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22772
Homologene: 5171
Snap91
Name: synaptosomal-associated protein 91
Synonyms: F1-20, 91kDa, AP180
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20616
Homologene: 8429
Fam171b
Name: family with sequence similarity 171, member B
Synonyms: D430039N05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241520
Homologene: 18462
Trappc3
Name: trafficking protein particle complex 3
Synonyms: 1110058K12Rik, Bet3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 27096
Homologene: 6399
Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms: D10Ertd733e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213783
Homologene: 18897
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52397
Homologene: 12971
Copg2
Name: coatomer protein complex, subunit gamma 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54160
HGNC: HGNC:2237
Homologene: 56292
Zmynd11
Name: zinc finger, MYND domain containing 11
Synonyms: 2210402G22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66505
Homologene: 4828
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: 9330197E15Rik, LOC380767, A630028O16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
Rabgef1
Name: RAB guanine nucleotide exchange factor (GEF) 1
Synonyms: Ras negative regulator Rabex-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56715
Homologene: 8720
Wdr18
Name: WD repeat domain 18
Synonyms: 2310012I10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216156
VEGA: 10
Homologene: 32573
Tmem108
Name: transmembrane protein 108
Synonyms: B130017P16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 81907
Homologene: 18688
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Anpep
Name: alanyl aminopeptidase, membrane
Synonyms: Cd13, aminopeptidase N, Apn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Gp2
Name: glycoprotein 2 zymogen granule membrane
Synonyms: 2310037I18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67133
HGNC: HGNC:4441
Homologene: 133790
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: 4930542A03Rik, USH1D, mdfw, ahl, nmf252, bob, nmf112, nmf181, sals
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Nkx2-5
Name: NK2 homeobox 5
Synonyms: tinman, Nkx-2.5, Csx, Nkx2.5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18091
HGNC: HGNC:2488
Homologene: 3230
Zbed5
Name: zinc finger BED-type containing 5
Synonyms: 2410018M08Rik, Zbed5, Chchd2l
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71970
Homologene: 84838
Hps3
Name: HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
Synonyms: Hermansky-Pudlak syndrome 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12807
Homologene: 13019
Cep19
Name: centrosomal protein 19
Synonyms: 1500031L02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66994
Homologene: 12065
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226652
Homologene: 18766
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 58178
Homologene: 10967
Pcsk2
Name: proprotein convertase subtilisin/kexin type 2
Synonyms: prohormone convertase 2, Nec-2, Phpp-2, Nec2, PC2, SPC2, 6330411F23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18549
HGNC: HGNC:8744
Homologene: 37640
Zscan10
Name: zinc finger and SCAN domain containing 10
Synonyms: Zscan10, Zfp206
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 332221
Homologene: 13122
Dpysl3
Name: dihydropyrimidinase-like 3
Synonyms: Ulip1, Ulip, CRMP-4, TUC4, 9430041P20Rik, CRMP4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 22240
HGNC: HGNC:3015
Homologene: 20361
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Slc38a4
Name: solute carrier family 38, member 4
Synonyms: Ata3, 1700012A18Rik, 1110012E16Rik, SNAT4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69354
VEGA: 15
Homologene: 75077
Gls2
Name: glutaminase 2 (liver, mitochondrial)
Synonyms: Lga, A330074B06Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216456
Homologene: 40861
Unc13c
Name: unc-13 homolog C
Synonyms: Munc13-3, Unc13h3, D9Ertd414e, 1500037O19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208898
Homologene: 45443
Brinp3
Name: bone morphogenetic protein/retinoic acid inducible neural specific 3
Synonyms: B830045N13Rik, Fam5c
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215378
Homologene: 17786
Ccr6
Name: C-C motif chemokine receptor 6
Synonyms: Cmkbr6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12458
VEGA: 17
HGNC: HGNC:1607
Homologene: 3214
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Abcb11
Name: ATP-binding cassette, sub-family B member 11
Synonyms: PFIC2, ABC16, PGY4, Lith1, sister of P-glycoprotein, Bsep
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27413
HGNC: HGNC:42
Homologene: 74509
Map6
Name: microtubule-associated protein 6
Synonyms: F-STOP, STOP, 2810411E12Rik, Mtap6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17760
HGNC: HGNC:6868
Homologene: 7850
Phldb3
Name: pleckstrin homology like domain, family B, member 3
Synonyms: EG232970, Gm10102
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232970
Homologene: 109375
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 252866
Homologene: 78104
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94229
Homologene: 23340
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320277
Homologene: 23371
Cyp2g1
Name: cytochrome P450, family 2, subfamily g, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13108
HGNC: HGNC:2633
Homologene: 75020
L3hypdh
Name: L-3-hydroxyproline dehydratase (trans-)
Synonyms: 2810055F11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67217
Homologene: 12100
Or2y10
Name: olfactory receptor family 2 subfamily Y member 10
Synonyms: GA_x6K02T2QP88-5871967-5871032, MOR256-66_i, Olfr1380
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 404336
Homologene: 72463
Aldh3b2
Name: aldehyde dehydrogenase 3 family, member B2
Synonyms: C130048D07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 621603
HGNC: HGNC:411
Homologene: 84430
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Vmn1r74
Name: vomeronasal 1 receptor 74
Synonyms: V1rg5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171240
Homologene: 110796
Or8k28
Name: olfactory receptor family 8 subfamily K member 28
Synonyms: GA_x6K02T2Q125-47925557-47924616, MOR188-8, MOR256-52P, Olfr1066
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257880
Homologene: 79468
Ilvbl
Name: ilvB (bacterial acetolactate synthase)-like
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216136
VEGA: 10
HGNC: HGNC:6041
Homologene: 68532
Cers3
Name: ceramide synthase 3
Synonyms: T3L, related to TRH3, LOC233330, CerS3, 4930550L11Rik, Lass3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545975
Homologene: 18719
Ccr8
Name: C-C motif chemokine receptor 8
Synonyms: Cmkbr8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12776
VEGA: 9
HGNC: HGNC:1609
Homologene: 21080
Gpcpd1
Name: glycerophosphocholine phosphodiesterase 1
Synonyms: 2310032D16Rik, 2310004G06Rik, Prei4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74182
Homologene: 10478
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Mfap3
Name: microfibrillar-associated protein 3
Synonyms: 2700079M14Rik, 2610509F16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216760
HGNC: HGNC:7034
Homologene: 4333
Or8b41
Name: olfactory receptor family 8 subfamily B member 41
Synonyms: GA_x6K02T2PVTD-31822365-31823309, MOR162-3, MOR162-15_p, Olfr890
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258474
Homologene: 138311
Gpx6
Name: glutathione peroxidase 6
Synonyms: olfactory, 1700020G18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75512
HGNC: HGNC:4558
Homologene: 130008
Igfals
Name: insulin-like growth factor binding protein, acid labile subunit
Synonyms: ALS, Albs
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16005
VEGA: 17
HGNC: HGNC:5468
Homologene: 37987
Cyp8b1
Name: cytochrome P450, family 8, subfamily b, polypeptide 1
Synonyms: sterol 12-alpha-hydrolase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13124
HGNC: HGNC:2653
Homologene: 3233
Zrsr2-ps1
Name: zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1
Synonyms: U2afbp-rs, Irlgs2, D11Ncvs75, 35kDa, SP2, U2af1-rs1, Zrsr1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22183
Homologene: 84793
Nhlrc1
Name: NHL repeat containing 1
Synonyms: B230309E09Rik, EPM2B, Malin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105193
VEGA: 13
Homologene: 18439
Cidea
Name: cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12683
VEGA: 18
HGNC: HGNC:1976
Homologene: 77852
Or52r1b
Name: olfactory receptor family 52 subfamily R member 1B
Synonyms: GA_x6K02T2PBJ9-5752857-5753801, MOR30-3, Olfr582
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259055
Homologene: 73943
Ccdc124
Name: coiled-coil domain containing 124
Synonyms: 1810023B24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234388
Homologene: 41702
Fbxo3
Name: F-box protein 3
Synonyms: Fba, 1200002G09Rik, 1700026K02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57443
Homologene: 8133
Esp1
Name: exocrine gland secreted peptide 1
Synonyms: ESP1, Gm6084
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619517
Pcdha8
Name: protocadherin alpha 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 353235
HGNC: HGNC:8675
Homologene: 129614
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 43,968,888 bp
  • A to T, chromosome 1 at 80,287,000 bp
  • T to A, chromosome 1 at 146,901,074 bp
  • G to A, chromosome 1 at 150,439,256 bp
  • T to C, chromosome 1 at 171,407,571 bp
  • A to G, chromosome 1 at 188,810,217 bp
  • T to A, chromosome 2 at 62,268,665 bp
  • A to T, chromosome 2 at 69,274,143 bp
  • T to C, chromosome 2 at 76,890,981 bp
  • A to G, chromosome 2 at 83,878,230 bp
  • T to A, chromosome 2 at 86,455,867 bp
  • T to C, chromosome 2 at 104,043,012 bp
  • G to A, chromosome 2 at 106,001,966 bp
  • T to A, chromosome 2 at 132,534,056 bp
  • A to G, chromosome 2 at 143,690,333 bp
  • A to G, chromosome 2 at 163,072,705 bp
  • A to T, chromosome 3 at 20,030,419 bp
  • T to C, chromosome 4 at 70,235,447 bp
  • C to T, chromosome 4 at 126,275,152 bp
  • T to A, chromosome 4 at 136,443,501 bp
  • A to T, chromosome 5 at 106,637,582 bp
  • G to T, chromosome 5 at 129,900,438 bp
  • A to T, chromosome 5 at 130,190,960 bp
  • A to T, chromosome 6 at 30,812,754 bp
  • C to T, chromosome 7 at 11,846,967 bp
  • G to A, chromosome 7 at 24,624,653 bp
  • A to T, chromosome 7 at 26,814,632 bp
  • A to T, chromosome 7 at 66,783,415 bp
  • A to T, chromosome 7 at 79,825,310 bp
  • G to T, chromosome 7 at 99,268,025 bp
  • C to A, chromosome 7 at 103,041,632 bp
  • A to G, chromosome 7 at 119,451,498 bp
  • A to T, chromosome 8 at 43,652,004 bp
  • A to T, chromosome 8 at 70,868,526 bp
  • T to C, chromosome 9 at 38,143,753 bp
  • T to A, chromosome 9 at 73,629,191 bp
  • C to T, chromosome 9 at 86,879,557 bp
  • T to C, chromosome 9 at 103,499,534 bp
  • T to A, chromosome 9 at 120,094,617 bp
  • G to A, chromosome 9 at 121,915,097 bp
  • T to C, chromosome 10 at 3,873,343 bp
  • T to A, chromosome 10 at 60,331,817 bp
  • T to C, chromosome 10 at 62,813,671 bp
  • C to T, chromosome 10 at 78,583,696 bp
  • G to A, chromosome 10 at 79,960,368 bp
  • G to T, chromosome 10 at 128,112,606 bp
  • C to A, chromosome 10 at 128,199,194 bp
  • A to G, chromosome 11 at 22,973,388 bp
  • C to T, chromosome 11 at 30,874,226 bp
  • T to A, chromosome 11 at 49,564,098 bp
  • T to A, chromosome 11 at 57,530,240 bp
  • A to G, chromosome 11 at 77,881,186 bp
  • T to C, chromosome 12 at 71,988,943 bp
  • C to T, chromosome 12 at 72,074,009 bp
  • T to C, chromosome 12 at 79,246,171 bp
  • A to T, chromosome 12 at 113,188,494 bp
  • T to C, chromosome 13 at 9,710,162 bp
  • T to A, chromosome 13 at 21,317,670 bp
  • A to G, chromosome 13 at 44,896,322 bp
  • A to G, chromosome 13 at 47,014,208 bp
  • A to T, chromosome 13 at 95,628,972 bp
  • T to C, chromosome 14 at 55,496,238 bp
  • T to C, chromosome 14 at 122,476,091 bp
  • A to T, chromosome 15 at 9,601,640 bp
  • G to T, chromosome 15 at 39,437,032 bp
  • T to C, chromosome 15 at 97,010,345 bp
  • T to C, chromosome 15 at 99,279,837 bp
  • T to A, chromosome 16 at 32,104,015 bp
  • A to G, chromosome 16 at 87,362,660 bp
  • T to C, chromosome 17 at 8,256,140 bp
  • G to A, chromosome 17 at 23,609,482 bp
  • T to C, chromosome 17 at 24,881,234 bp
  • G to A, chromosome 17 at 25,243,840 bp
  • T to C, chromosome 17 at 26,839,620 bp
  • A to G, chromosome 17 at 40,731,081 bp
  • C to T, chromosome 18 at 12,582,608 bp
  • T to G, chromosome 18 at 36,993,148 bp
  • T to C, chromosome 18 at 43,438,042 bp
  • T to C, chromosome 18 at 67,366,421 bp
  • A to C, chromosome 19 at 3,979,592 bp
  • G to A, chromosome 19 at 6,388,863 bp
  • T to C, chromosome 19 at 46,453,277 bp
  • C to T, chromosome 19 at 50,190,042 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7223 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045295-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.