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Strain Name:
C57BL/6J-MtgxR7213Btlr/Mmmh
Stock Number:
045341-MU
Citation ID:
RRID:MMRRC_045341-MU
Other Names:
R7213 (G1)
Major Collection:

Strain Information

Gpr26
Name: G protein-coupled receptor 26
Synonyms: 9630036A11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233919
HGNC: HGNC:4481
Homologene: 17764
Gpr139
Name: G protein-coupled receptor 139
Synonyms: LOC209776, GPRg1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 209776
Homologene: 45860
Gk5
Name: glycerol kinase 5
Synonyms: G630067D24Rik, C330018K18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235533
Homologene: 15141
Timeless
Name: timeless circadian clock 1
Synonyms: tim
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21853
Homologene: 31206
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Dsk9, Mhdadsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 36,702,140 bp
  • G to C, chromosome 1 at 60,237,151 bp
  • A to T, chromosome 1 at 75,215,697 bp
  • G to A, chromosome 1 at 97,127,946 bp
  • A to T, chromosome 1 at 138,853,629 bp
  • T to A, chromosome 1 at 158,936,886 bp
  • A to G, chromosome 2 at 35,135,680 bp
  • T to C, chromosome 2 at 76,725,761 bp
  • A to T, chromosome 2 at 85,353,556 bp
  • C to T, chromosome 2 at 92,413,659 bp
  • A to T, chromosome 2 at 140,244,135 bp
  • T to A, chromosome 2 at 150,239,465 bp
  • G to A, chromosome 2 at 154,165,983 bp
  • C to T, chromosome 2 at 163,864,061 bp
  • C to A, chromosome 3 at 5,396,644 bp
  • G to A, chromosome 3 at 38,999,087 bp
  • C to T, chromosome 4 at 59,914,279 bp
  • T to C, chromosome 5 at 23,844,061 bp
  • T to C, chromosome 5 at 84,233,923 bp
  • T to C, chromosome 5 at 108,404,090 bp
  • C to T, chromosome 5 at 115,242,473 bp
  • T to C, chromosome 5 at 115,242,474 bp
  • A to T, chromosome 5 at 122,921,469 bp
  • G to A, chromosome 6 at 60,944,543 bp
  • A to T, chromosome 6 at 139,860,264 bp
  • T to C, chromosome 7 at 12,601,056 bp
  • A to G, chromosome 7 at 16,120,779 bp
  • G to T, chromosome 7 at 24,104,513 bp
  • T to A, chromosome 7 at 55,806,112 bp
  • T to A, chromosome 7 at 119,145,099 bp
  • T to C, chromosome 7 at 131,967,490 bp
  • T to C, chromosome 7 at 140,008,014 bp
  • T to A, chromosome 7 at 144,031,409 bp
  • A to T, chromosome 8 at 36,146,615 bp
  • T to C, chromosome 8 at 41,084,487 bp
  • A to G, chromosome 8 at 70,816,453 bp
  • A to T, chromosome 8 at 91,391,507 bp
  • C to T, chromosome 8 at 123,090,232 bp
  • A to G, chromosome 9 at 18,641,416 bp
  • A to T, chromosome 9 at 20,639,008 bp
  • C to T, chromosome 9 at 36,128,650 bp
  • C to T, chromosome 9 at 96,145,712 bp
  • C to T, chromosome 9 at 108,849,040 bp
  • G to T, chromosome 9 at 124,293,900 bp
  • A to G, chromosome 10 at 76,408,904 bp
  • A to G, chromosome 10 at 80,116,618 bp
  • A to T, chromosome 10 at 85,876,309 bp
  • G to A, chromosome 10 at 120,978,240 bp
  • T to C, chromosome 10 at 128,243,289 bp
  • A to T, chromosome 11 at 43,036,408 bp
  • A to T, chromosome 11 at 46,121,471 bp
  • A to T, chromosome 11 at 55,281,045 bp
  • A to G, chromosome 11 at 70,553,372 bp
  • A to G, chromosome 11 at 70,772,525 bp
  • A to T, chromosome 11 at 74,085,863 bp
  • C to A, chromosome 11 at 78,232,150 bp
  • A to G, chromosome 11 at 79,469,819 bp
  • G to T, chromosome 11 at 97,754,029 bp
  • T to C, chromosome 11 at 100,258,530 bp
  • A to T, chromosome 12 at 21,336,678 bp
  • A to T, chromosome 12 at 31,937,197 bp
  • G to T, chromosome 13 at 23,751,163 bp
  • T to A, chromosome 13 at 100,187,483 bp
  • T to A, chromosome 13 at 113,317,941 bp
  • T to A, chromosome 14 at 31,143,673 bp
  • A to G, chromosome 14 at 43,819,154 bp
  • A to C, chromosome 14 at 45,657,753 bp
  • A to G, chromosome 14 at 65,299,419 bp
  • A to T, chromosome 14 at 70,558,350 bp
  • G to A, chromosome 14 at 123,973,297 bp
  • A to G, chromosome 15 at 74,569,884 bp
  • T to C, chromosome 15 at 82,016,826 bp
  • A to G, chromosome 16 at 56,701,153 bp
  • C to T, chromosome 16 at 58,450,763 bp
  • T to C, chromosome 17 at 38,149,074 bp
  • G to T, chromosome 18 at 5,094,574 bp
  • G to A, chromosome 18 at 12,687,081 bp
  • T to C, chromosome 19 at 5,660,523 bp
  • T to C, chromosome 19 at 26,647,131 bp
  • C to A, chromosome 19 at 41,120,227 bp
  • T to C, chromosome 19 at 56,529,635 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7213 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045341-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.