Strain Name:
C57BL/6J-MtgxR7241Btlr/Mmmh
Stock Number:
045348-MU
Citation ID:
RRID:MMRRC_045348-MU
Other Names:
R7241 (G1)
Major Collection:

Strain Information

B4galt5
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
Synonyms: 9430078I07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56336
HGNC: HGNC:928
Homologene: 3507
Rabep1
Name: rabaptin, RAB GTPase binding effector protein 1
Synonyms: rabaptin-5, RAB5 effector protein, neurocrescin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54189
Homologene: 3451
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Drd5
Name: dopamine receptor D5
Synonyms: Drd1b, D5R, Drd-5, DRD1b, Gpcr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Prkd2
Name: protein kinase D2
Synonyms: PKD2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101540
Homologene: 9516
Washc2
Name: WASH complex subunit 2
Synonyms: Fam21, D6Wsu116e, C530005J20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28006
Homologene: 41686
Mast4
Name: microtubule associated serine/threonine kinase family member 4
Synonyms: 4930420O11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 328329
Homologene: 42094
Mrps27
Name: mitochondrial ribosomal protein S27
Synonyms: 2610028H14Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218506
VEGA: 13
Homologene: 41006
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: Copb1, 2610019B04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Dock4
Name: dedicator of cytokinesis 4
Synonyms: 6330411N01Rik, EST N28122
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Itpr-1, Ip3r, Pcp1, InsP3R type I, P400, wblo, Pcp-1, IP3R1, opt
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ankyrin-3, AnkG, Ank-3, 2900054D09Rik, Ankyrin-G
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: 150kDa, TAFII150, TAF2B, CIF150, 4732460C16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Tfcp2
Name: transcription factor CP2
Synonyms: LBP-1d, UBP-1, CP-2, Tcfcp2, LBP1, CP2, D230015P20Rik, LSF, LBP-1c
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 21422
VEGA: 15
Homologene: 4134
Prdm15
Name: PR domain containing 15
Synonyms: E130018M06Rik, Zfp298
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 114604
Homologene: 56941
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 277939
Homologene: 19524
Nbn
Name: nibrin
Synonyms: Nbs1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 27354
HGNC: HGNC:7652
Homologene: 1858
Thrsp
Name: thyroid hormone responsive
Synonyms: S14, Spot 14
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21835
Homologene: 2441
Uhrf1
Name: ubiquitin-like, containing PHD and RING finger domains, 1
Synonyms: ICBP90, Np95
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18140
Homologene: 7866
Unc5a
Name: unc-5 netrin receptor A
Synonyms: Unc5h1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107448
Homologene: 41474
Impdh2
Name: inosine monophosphate dehydrogenase 2
Synonyms: IMP dehydrogenase type II
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23918
HGNC: HGNC:6053
Homologene: 48919
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC385637, LOC224088, LOC224087
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224088
Homologene: 23455
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: p600, LOC381562, 1810009A16Rik, D930005K06Rik, A930005E13Rik, Zubr1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Arhgap33
Name: Rho GTPase activating protein 33
Synonyms: Tcgap, Snx26, NOMA-GAP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233071
Homologene: 76448
Adam32
Name: a disintegrin and metallopeptidase domain 32
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 353188
Homologene: 17021
Sez6l
Name: seizure related 6 homolog like
Synonyms: Acig1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56747
Homologene: 10895
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: Dnahc1, B230373P09Rik, G1-415-19, ferf1, MDHC7, E030034C22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
Synonyms: CaT2, ECaC1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194352
HGNC: HGNC:3145
Homologene: 10520
Zfpl1
Name: zinc finger like protein 1
Synonyms: 1500015B20Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 81909
Homologene: 4935
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Ttn
Name: titin
Synonyms: connectin, 1100001C23Rik, D330041I19Rik, D830007G01Rik, 2310074I15Rik, 2310036G12Rik, mdm, 2310057K23Rik, shru, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Txnip
Name: thioredoxin interacting protein
Synonyms: mVDUP1, THIF, VDUP1, Hyplip1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56338
Homologene: 38186
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Fcsk
Name: fucose kinase
Synonyms: 1110046B12Rik, L-fucose kinase, Fuk
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234730
Homologene: 15452
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Or1e35
Name: olfactory receptor family 1 subfamily E member 35
Synonyms: Olfr395, GA_x6K02T2P1NL-4062605-4061667, MOR135-10
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259007
Lrriq1
Name: leucine-rich repeats and IQ motif containing 1
Synonyms: LOC380658, Gm1557, 4930503E15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74978
Homologene: 46007
Eeig1
Name: estrogen-induced osteoclastogenesis regulator 1
Synonyms: Fam102a, C230093N12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98952
Homologene: 51943
Ahnak
Name: AHNAK nucleoprotein
Synonyms: 2310047C17Rik, 1110004P15Rik, DY6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Cgnl1
Name: cingulin-like 1
Synonyms: 4933421H10Rik, 9930020M10Rik, Jacop
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68178
Homologene: 41901
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Kansl1l
Name: KAT8 regulatory NSL complex subunit 1-like
Synonyms: C430010P07Rik, 1110028C15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68691
Homologene: 27376
Hltf
Name: helicase-like transcription factor
Synonyms: Smarca3, Snf2l3, P113
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20585
Homologene: 30136
Gjc2
Name: gap junction protein, gamma 2
Synonyms: Gja12, B230382L12Rik, Cx47, connexin 47
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 118454
Homologene: 10715
Tlr11
Name: toll-like receptor 11
Synonyms: LOC239081
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239081
Homologene: 77905
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Kif14
Name: kinesin family member 14
Synonyms: D1Ertd367e, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381293
Homologene: 8916
Abca14
Name: ATP-binding cassette, sub-family A member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67928
Homologene: 86128
Cyp2c50
Name: cytochrome P450, family 2, subfamily c, polypeptide 50
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107141
Homologene: 137231
Adam9
Name: ADAM metallopeptidase domain 9
Synonyms: Mltng, MDC9, Mltng, MDC9
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11502
HGNC: HGNC:216
Homologene: 20824
Tbc1d7
Name: TBC1 domain family, member 7
Synonyms: 2610009C09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67046
VEGA: 13
Homologene: 9538
Polr1e
Name: polymerase (RNA) I polypeptide E
Synonyms: Paf53, Praf1, 53kDa, D030019D19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64424
Homologene: 41486
Gzmd
Name: granzyme D
Synonyms: Ctla-5, Ctla5, CCP5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14941
Homologene: 133275
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: ALP56, CDA13, 1110059C24Rik, ASP21, CEAP1, ARP1, BAE2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Mex3d
Name: mex3 RNA binding family member D
Synonyms: Rkhd1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237400
Homologene: 16890
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Plaat5
Name: phospholipase A and acyltransferase 5
Synonyms: 1700055A14Rik, 4921526K24Rik, iNAT, 1700086E08Rik, Hrasls5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66727
Homologene: 12019
Prkn
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: Parkin, PRKN, Park2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50873
HGNC: HGNC:8607
Homologene: 3355
Ttll13
Name: tubulin tyrosine ligase-like family, member 13
Synonyms: 1700111A04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269954
Homologene: 136186
Pou6f2
Name: POU domain, class 6, transcription factor 2
Synonyms: D130006K24Rik, RPF-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218030
Cep250
Name: centrosomal protein 250
Synonyms: B230210E21Rik, Cep2, Inmp
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212974
Homologene: 16023
Cyp4a32
Name: cytochrome P450, family 4, subfamily a, polypeptide 32
Synonyms: OTTMUSG00000008689
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100040843
HGNC: HGNC:2642
Homologene: 128044
Prkcz
Name: protein kinase C, zeta
Synonyms: aPKCzeta, Pkcz, zetaPKC
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18762
HGNC: HGNC:9412
Homologene: 55681
Ift88
Name: intraflagellar transport 88
Synonyms: Tg737Rpw, polaris, Ttc10, Oak Ridge polycystic kidneys, orpk, fxo, IFT88, Tg737, TgN737Rpw
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21821
Homologene: 4761
Ganc
Name: glucosidase, alpha; neutral C
Synonyms: 5830445O15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76051
HGNC: HGNC:4139
Homologene: 25627
Or8k35
Name: olfactory receptor family 8 subfamily K member 35
Synonyms: GA_x6K02T2Q125-48079993-48079157, MOR192-4_p, Olfr1082
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404473
Homologene: 104285
Toe1
Name: target of EGR1, member 1 (nuclear)
Synonyms: 4930584N22Rik, 4933424D16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68276
Homologene: 11823
Cyth4
Name: cytohesin 4
Synonyms: 5830469K17Rik, 2510004M07Rik, Pscd4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72318
VEGA: 15
HGNC: HGNC:9505
Homologene: 22750
Zfp174
Name: zinc finger protein 174
Synonyms: LOC385674
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 385674
Homologene: 55755
Sectm1a
Name: secreted and transmembrane 1A
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 209588
Homologene: 134112
Tnnt2
Name: troponin T2, cardiac
Synonyms: cTnT, cardiac TnT, Tnt
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21956
Homologene: 68050
Rptn
Name: repetin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20129
Homologene: 84780
Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
Synonyms: Gm10937, LOC380650, C030032C09Rik, E530015N03Rik, AIDA-1b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77531
Homologene: 51570
Ccr4
Name: C-C motif chemokine receptor 4
Synonyms: CC CKR-4, Cmkbr4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12773
VEGA: 9
HGNC: HGNC:1605
Homologene: 21135
Vmn1r123
Name: vomeronasal 1 receptor 123
Synonyms: LOC384695, Gm1446
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384695
Homologene: 104166
Vmn1r180
Name: vomeronasal 1 receptor 180
Synonyms: V1rd16, LOC232962
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232962
Homologene: 104166
Flvcr2
Name: feline leukemia virus subgroup C cellular receptor 2
Synonyms: Mfsd7c, CCT
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217721
VEGA: 12
Homologene: 9840
Timm10
Name: translocase of inner mitochondrial membrane 10
Synonyms: Tim13, Timm13a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 30059
Homologene: 40845
Kif19b
Name: kinesin family member 19B
Synonyms: Gm4869
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 101055939
Homologene: 82478
Ighv1-62-1
Name: immunoglobulin heavy variable 1-62-1
Synonyms: Gm9232
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668544
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 66,801,628 bp
  • T to A, chromosome 1 at 135,851,706 bp
  • T to A, chromosome 1 at 136,468,753 bp
  • A to G, chromosome 2 at 32,558,064 bp
  • A to G, chromosome 2 at 76,953,206 bp
  • T to A, chromosome 2 at 84,829,989 bp
  • C to A, chromosome 2 at 86,594,154 bp
  • T to A, chromosome 2 at 120,441,529 bp
  • T to C, chromosome 2 at 125,306,495 bp
  • A to T, chromosome 2 at 155,991,552 bp
  • A to G, chromosome 2 at 167,306,697 bp
  • T to A, chromosome 3 at 20,065,392 bp
  • A to G, chromosome 3 at 93,395,954 bp
  • T to C, chromosome 3 at 96,559,675 bp
  • A to T, chromosome 4 at 15,991,190 bp
  • A to C, chromosome 4 at 45,029,340 bp
  • A to G, chromosome 4 at 115,602,302 bp
  • A to T, chromosome 4 at 116,807,518 bp
  • G to A, chromosome 4 at 139,443,414 bp
  • A to T, chromosome 4 at 155,269,059 bp
  • A to G, chromosome 5 at 38,320,536 bp
  • T to C, chromosome 5 at 112,473,480 bp
  • G to A, chromosome 5 at 114,245,100 bp
  • A to G, chromosome 5 at 140,462,188 bp
  • G to A, chromosome 6 at 41,675,308 bp
  • T to C, chromosome 6 at 108,517,620 bp
  • A to G, chromosome 6 at 116,208,207 bp
  • G to T, chromosome 7 at 16,857,805 bp
  • A to T, chromosome 7 at 21,162,612 bp
  • T to A, chromosome 7 at 23,952,466 bp
  • A to G, chromosome 7 at 30,528,721 bp
  • A to C, chromosome 7 at 80,254,163 bp
  • G to T, chromosome 7 at 97,417,088 bp
  • A to C, chromosome 7 at 100,407,050 bp
  • C to T, chromosome 7 at 114,237,356 bp
  • T to C, chromosome 7 at 119,943,633 bp
  • A to G, chromosome 7 at 120,246,961 bp
  • T to C, chromosome 7 at 140,945,720 bp
  • T to C, chromosome 8 at 24,898,494 bp
  • T to A, chromosome 8 at 24,950,986 bp
  • A to G, chromosome 8 at 110,895,897 bp
  • T to C, chromosome 9 at 71,724,770 bp
  • A to G, chromosome 9 at 108,563,437 bp
  • T to C, chromosome 9 at 114,492,956 bp
  • G to A, chromosome 10 at 69,706,814 bp
  • T to C, chromosome 10 at 80,387,257 bp
  • T to C, chromosome 10 at 82,287,042 bp
  • T to G, chromosome 10 at 90,512,837 bp
  • A to C, chromosome 10 at 103,215,973 bp
  • T to A, chromosome 11 at 59,177,134 bp
  • C to A, chromosome 11 at 70,939,989 bp
  • T to C, chromosome 11 at 73,907,232 bp
  • T to A, chromosome 11 at 83,351,105 bp
  • T to A, chromosome 11 at 121,069,882 bp
  • A to G, chromosome 12 at 40,794,860 bp
  • T to A, chromosome 12 at 85,805,239 bp
  • C to A, chromosome 12 at 115,386,702 bp
  • A to T, chromosome 13 at 11,665,913 bp
  • A to G, chromosome 13 at 18,125,289 bp
  • T to C, chromosome 13 at 43,153,017 bp
  • A to T, chromosome 13 at 54,991,020 bp
  • A to T, chromosome 13 at 99,411,280 bp
  • G to A, chromosome 13 at 103,334,000 bp
  • T to C, chromosome 14 at 31,264,939 bp
  • T to A, chromosome 14 at 50,362,141 bp
  • G to A, chromosome 14 at 56,131,342 bp
  • A to G, chromosome 14 at 57,479,997 bp
  • T to A, chromosome 15 at 55,062,141 bp
  • A to G, chromosome 15 at 78,607,045 bp
  • T to C, chromosome 15 at 100,518,587 bp
  • C to A, chromosome 16 at 3,848,247 bp
  • T to A, chromosome 16 at 30,352,277 bp
  • T to C, chromosome 16 at 97,436,798 bp
  • T to C, chromosome 16 at 97,795,741 bp
  • C to A, chromosome 17 at 11,854,861 bp
  • A to G, chromosome 17 at 33,579,928 bp
  • T to C, chromosome 17 at 56,315,193 bp
  • A to G, chromosome 18 at 25,060,352 bp
  • T to C, chromosome 19 at 6,081,913 bp
  • A to G, chromosome 19 at 7,614,581 bp
  • A to G, chromosome 19 at 9,009,031 bp
  • T to A, chromosome 19 at 40,090,568 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7241 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045348-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.