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Strain Name:
C57BL/6J-MtgxR7480Btlr/Mmmh
Stock Number:
045554-MU
Citation ID:
RRID:MMRRC_045554-MU
Other Names:
R7480 (G1)
Major Collection:

Strain Information

Thbs4
Name: thrombospondin 4
Synonyms: TSP-4, TSP4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21828
Homologene: 20691
Rai14
Name: retinoic acid induced 14
Synonyms: 1700020L11Rik, Ankycorbin, Norpeg, 1700008J19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75646
VEGA: 15
Homologene: 9199
Plekha7
Name: pleckstrin homology domain containing, family A member 7
Synonyms: A430081P20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233765
Homologene: 52172
Wnt7a
Name: wingless-type MMTV integration site family, member 7A
Synonyms: Wnt-7a, tw
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22421
Homologene: 20969
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: E130319N12Rik, 2810017C20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215351
Homologene: 9196
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 6030449K19Rik, 2900036C23Rik, 2410152H17Rik, 2810413I22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66315
Homologene: 10778
Pafah1b1
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
Synonyms: Lis1, LIS-1, lissencephaly-1 protein, Mdsh, Pafaha, PAF-AH 45
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18472
HGNC: HGNC:8574
Homologene: 371
Tango6
Name: transport and golgi organization 6
Synonyms: Tmco7, Tango6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 272538
Homologene: 52121
Epb41l3
Name: erythrocyte membrane protein band 4.1 like 3
Synonyms: NBL3, 4.1B, DAL1P, Epb4.1l3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13823
HGNC: HGNC:3380
Homologene: 49308
Xpo6
Name: exportin 6
Synonyms: Ranbp20, 2610005L19Rik, C230091E20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74204
Homologene: 12544
Mxi1
Name: MAX interactor 1, dimerization protein
Synonyms: Mad2, bHLHc11
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 17859
VEGA: 19
HGNC: HGNC:7534
Homologene: 4351
Bicc1
Name: BicC family RNA binding protein 1
Synonyms: Bic-C, jcpk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83675
Homologene: 12856
Oprd1
Name: opioid receptor, delta 1
Synonyms: DOR-1, Nbor, mDOR, DOR
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18386
HGNC: HGNC:8153
Homologene: 20252
Casz1
Name: castor zinc finger 1
Synonyms: 2410019P08Rik, D4Ertd432e, castor, Cst
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69743
Homologene: 9824
Mpzl1
Name: myelin protein zero-like 1
Synonyms: 1110007A10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68481
HGNC: HGNC:7226
Homologene: 2939
Dapk1
Name: death associated protein kinase 1
Synonyms: 2310039H24Rik, D13Ucla1, 2810425C21Rik, DAP-Kinase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234839
Homologene: 124356
Slamf9
Name: SLAM family member 9
Synonyms: CD2F-10, 2310026I04Rik, SF2001, CD84-H1, Cd2f10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98365
Homologene: 12642
Rasl11b
Name: RAS-like, family 11, member B
Synonyms: 1190017B18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68939
Homologene: 74291
Dlk1
Name: delta like non-canonical Notch ligand 1
Synonyms: pref-1, pG2, ZOG, SCP1, FA1, Peg9, DlkI
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13386
HGNC: HGNC:2907
Homologene: 2846
C1ql3
Name: C1q-like 3
Synonyms: K100, 1110065A22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227580
Homologene: 17701
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75050
VEGA: 13
Homologene: 69235
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Scaf1
Name: SR-related CTD-associated factor 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233208
Pde5a
Name: phosphodiesterase 5A, cGMP-specific
Synonyms: PDE5A1, Pde5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242202
HGNC: HGNC:8784
Homologene: 842
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Ulk3
Name: unc-51-like kinase 3
Synonyms: 1200015E14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71742
VEGA: 9
Homologene: 68482
Vmn1r179
Name: vomeronasal 1 receptor 179
Synonyms: V1rd17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404286
Homologene: 134022
Col19a1
Name: collagen, type XIX, alpha 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12823
HGNC: HGNC:2196
Homologene: 55608
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 81877
Homologene: 49589
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, Follitropin receptor, FSH-R
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Slc8a1
Name: solute carrier family 8 (sodium/calcium exchanger), member 1
Synonyms: Ncx1, D930008O12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20541
VEGA: 17
Homologene: 69090
Nt5dc1
Name: 5'-nucleotidase domain containing 1
Synonyms: 6030401B09Rik, Nt5c2l1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319638
Homologene: 16281
Wrap73
Name: WD repeat containing, antisense to Trp73
Synonyms: DD57, 2610044M17Rik, 5330425N03Rik, Wdr8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 59002
Homologene: 9857
Eri2
Name: exoribonuclease 2
Synonyms: 4933424N09Rik, Exod1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71151
Homologene: 12383
Or6f1
Name: olfactory receptor family 6 subfamily F member 1
Synonyms: GA_x6K02T2NHDJ-9786435-9787361, MOR104-1, Olfr308
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258614
Homologene: 27225
Herc6
Name: hect domain and RLD 6
Synonyms: 4930427L17Rik, 1700121D12Rik, CEB1, 2510038N07Rik, Herc5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67138
Homologene: 70768
Rassf8
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Synonyms: mHoj-1, 5133400D11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71323
Homologene: 5219
Klk13
Name: kallikrein related-peptidase 13
Synonyms: mGk-13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 626834
HGNC: HGNC:6361
Homologene: 56714
Hif3a
Name: hypoxia inducible factor 3, alpha subunit
Synonyms: MOP7, bHLHe17, Nepas
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 53417
Homologene: 9646
Tfb2m
Name: transcription factor B2, mitochondrial
Synonyms: Hkp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15278
Homologene: 7362
Galk2
Name: galactokinase 2
Synonyms: Gk2, 2810017M24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69976
HGNC: HGNC:4119
Homologene: 13654
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 639774
Homologene: 106613
Iqca1l
Name: IQ motif containing with AAA domain 1 like
Synonyms: 4931409K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231045
Homologene: 18602
Apol10b
Name: apolipoprotein L 10B
Synonyms: 9130218O11Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328561
Homologene: 129975
Cr2
Name: complement receptor 2
Synonyms: CD21, CD35, Cr-1, Cr-2, Cr1, C3DR
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Garin1a
Name: golgi associated RAB2 interactor 1A
Synonyms: Fam71f2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 245884
Homologene: 52974
Smpdl3a
Name: sphingomyelin phosphodiesterase, acid-like 3A
Synonyms: 0610010C24Rik, ASM3A, ASML3A
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57319
Homologene: 4886
Nfxl1
Name: nuclear transcription factor, X-box binding-like 1
Synonyms: TCF9, LOC381696, D430033A06Rik, 1700012H24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100978
Homologene: 26752
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: 6330406L22Rik, Hmha1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70719
Homologene: 69120
Ces2f
Name: carboxylesterase 2F
Synonyms: 2310038E17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71903
HGNC: HGNC:1864
Homologene: 135673
Zfp764l1
Name: zinc finger protein 764 like 1
Synonyms: E430018J23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101604
Homologene: 138471
Prdm11
Name: PR domain containing 11
Synonyms: 8030443D09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100042784
Homologene: 82511
Vmn1r54
Name: vomeronasal 1 receptor 54
Synonyms: VN7, V1ra9
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113851
Or4k38
Name: olfactory receptor family 4 subfamily K member 38
Synonyms: GA_x6K02T2Q125-72387537-72386620, MOR248-16, MOR248-2, Olfr1557, Olfr1282
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258909
Homologene: 73992
Or7e173
Name: olfactory receptor family 7 subfamily E member 173
Synonyms: GA_x6K02T2PVTD-13768406-13767468, MOR145-5, Olfr866
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258551
HGNC: HGNC:8396
Homologene: 133687
Alg9
Name: ALG9 alpha-1,2-mannosyltransferase
Synonyms: 8230402H15Rik, B430313H07Rik, Dibd1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102580
Homologene: 6756
Csf1r
Name: colony stimulating factor 1 receptor
Synonyms: CSF-1R, M-CSFR, CD115, Fms, Fim-2, Csfmr, Fim2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12978
HGNC: HGNC:2433
Homologene: 3817
Taar9
Name: trace amine-associated receptor 9
Synonyms: Tar3, Ta3, Trar3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 503558
Homologene: 65286
Or1f19
Name: olfactory receptor family 1 subfamily F member 19
Synonyms: MOR131-1, GA_x54KRFPKG5P-112942-113883, Olfr161
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258859
Homologene: 51784
Reg3a
Name: regenerating islet-derived 3 alpha
Synonyms: RegIII (alpha)
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19694
HGNC: HGNC:8601
Homologene: 136247
Kctd14
Name: potassium channel tetramerisation domain containing 14
Synonyms: D7Ertd760e, AI449310
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233529
Homologene: 11396
Gm7356
Name: predicted gene 7356
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 664821
Homologene: 133217
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 24,317,707 bp
  • A to T, chromosome 1 at 150,677,234 bp
  • A to G, chromosome 1 at 165,604,688 bp
  • G to A, chromosome 1 at 172,477,473 bp
  • A to G, chromosome 1 at 179,529,182 bp
  • C to T, chromosome 1 at 195,154,176 bp
  • A to T, chromosome 2 at 13,010,339 bp
  • T to C, chromosome 2 at 92,975,324 bp
  • A to G, chromosome 2 at 111,335,392 bp
  • A to G, chromosome 2 at 125,946,925 bp
  • A to T, chromosome 3 at 122,803,148 bp
  • A to T, chromosome 4 at 111,928,587 bp
  • A to G, chromosome 4 at 132,117,181 bp
  • T to C, chromosome 4 at 143,895,495 bp
  • T to C, chromosome 4 at 148,944,586 bp
  • A to G, chromosome 4 at 154,152,586 bp
  • T to G, chromosome 5 at 24,546,906 bp
  • C to T, chromosome 5 at 72,559,252 bp
  • T to A, chromosome 5 at 74,198,110 bp
  • T to A, chromosome 5 at 146,539,501 bp
  • G to A, chromosome 6 at 29,281,436 bp
  • C to T, chromosome 6 at 57,581,221 bp
  • C to T, chromosome 6 at 78,382,347 bp
  • A to G, chromosome 6 at 90,269,178 bp
  • C to A, chromosome 6 at 91,394,413 bp
  • T to A, chromosome 6 at 145,820,031 bp
  • G to A, chromosome 7 at 17,042,635 bp
  • A to T, chromosome 7 at 23,929,133 bp
  • T to A, chromosome 7 at 24,181,882 bp
  • T to C, chromosome 7 at 43,721,422 bp
  • C to T, chromosome 7 at 45,007,649 bp
  • A to G, chromosome 7 at 86,321,680 bp
  • T to C, chromosome 7 at 97,458,224 bp
  • A to T, chromosome 7 at 116,137,168 bp
  • T to A, chromosome 7 at 119,786,511 bp
  • T to C, chromosome 7 at 125,642,541 bp
  • G to A, chromosome 7 at 126,102,333 bp
  • C to T, chromosome 7 at 127,393,324 bp
  • A to G, chromosome 8 at 104,954,706 bp
  • A to T, chromosome 8 at 106,696,727 bp
  • A to T, chromosome 8 at 122,498,495 bp
  • C to T, chromosome 9 at 20,027,934 bp
  • T to G, chromosome 9 at 50,822,628 bp
  • C to T, chromosome 9 at 57,591,240 bp
  • T to C, chromosome 9 at 80,121,917 bp
  • T to A, chromosome 10 at 24,108,945 bp
  • C to A, chromosome 10 at 34,324,453 bp
  • C to T, chromosome 10 at 34,324,454 bp
  • A to G, chromosome 10 at 57,802,478 bp
  • T to C, chromosome 10 at 70,943,476 bp
  • T to A, chromosome 10 at 80,027,102 bp
  • A to C, chromosome 11 at 74,685,914 bp
  • T to A, chromosome 12 at 109,455,614 bp
  • A to T, chromosome 13 at 58,288,211 bp
  • A to G, chromosome 13 at 60,757,497 bp
  • G to A, chromosome 13 at 92,767,221 bp
  • C to A, chromosome 15 at 10,571,536 bp
  • G to T, chromosome 15 at 74,707,053 bp
  • G to T, chromosome 15 at 77,588,788 bp
  • A to T, chromosome 16 at 3,592,629 bp
  • G to A, chromosome 16 at 56,155,226 bp
  • A to G, chromosome 17 at 14,001,065 bp
  • A to G, chromosome 17 at 34,715,773 bp
  • A to T, chromosome 17 at 46,537,812 bp
  • A to C, chromosome 17 at 69,261,872 bp
  • T to C, chromosome 17 at 81,649,220 bp
  • A to C, chromosome 17 at 88,985,374 bp
  • T to G, chromosome 18 at 61,117,538 bp
  • A to G, chromosome 19 at 53,371,635 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7480 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045554-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.