Strain Name:
C57BL/6J-MtgxR7488Btlr/Mmmh
Stock Number:
045562-MU
Citation ID:
RRID:MMRRC_045562-MU
Other Names:
R7488 (G1)
Major Collection:

Strain Information

Cdk4
Name: cyclin dependent kinase 4
Synonyms: p34PSK-J3/cdk4, Crk3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12567
HGNC: HGNC:1773
Homologene: 55429
Gsn
Name: gelsolin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227753
HGNC: HGNC:4620
Homologene: 147
Tfdp2
Name: transcription factor Dp 2
Synonyms: DP3, DP-3, DP3, A330080J22Rik, 1110029I05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 211586
Homologene: 4578
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Por
Name: cytochrome p450 oxidoreductase
Synonyms: NADH cytochrome P450 oxydoreductase, CYPOR, CPR, 4933424M13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18984
HGNC: HGNC:9208
Homologene: 725
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Wwp1
Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: SDRP1, Tiul1, AIP5, 8030445B08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107568
Homologene: 21385
Ccz1
Name: CCZ1 vacuolar protein trafficking and biogenesis associated
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231874
Homologene: 56717
Asap1
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain1
Synonyms: Ddef1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13196
HGNC: HGNC:2720
Homologene: 7684
Ddx54
Name: DEAD box helicase 54
Synonyms: APR-5, DP97, 2410015A15Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71990
Homologene: 5590
Tnpo2
Name: transportin 2 (importin 3, karyopherin beta 2b)
Synonyms: Kpnb2b, TRN2, 1110034O24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212999
Homologene: 8381
Cpne1
Name: copine I
Synonyms: 1810028N16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 266692
HGNC: HGNC:2314
Homologene: 36501
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11736
Homologene: 9491
Emsy
Name: EMSY, BRCA2-interacting transcriptional repressor
Synonyms: 2210018M11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233545
Homologene: 32465
Apaf1
Name: apoptotic peptidase activating factor 1
Synonyms: Apaf1l, 6230400I06Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11783
HGNC: HGNC:576
Homologene: 7626
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 2700033G17Rik, 9630050P21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Ezh1
Name: enhancer of zeste 1 polycomb repressive complex 2 subunit
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14055
HGNC: HGNC:3526
Homologene: 20458
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Rock1
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: Rock-I, 1110055K06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19877
VEGA: 18
Homologene: 55899
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: 5830462I21Rik, JHDM2B, Jmjd1b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Apobec1
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11810
HGNC: HGNC:604
Homologene: 1243
Zfp451
Name: zinc finger protein 451
Synonyms: Kiaa0576-hp, 4930515K21Rik, 4933435G09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98403
Homologene: 9188
Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms: D10Ertd733e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213783
Homologene: 18897
Bcr
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, breakpoint cluster region
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110279
VEGA: 10
HGNC: HGNC:1014
Homologene: 3192
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, Dnchc2, b2b414Clo, m407Asp, m152Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Rpl6
Name: ribosomal protein L6
Synonyms: Taxreb107
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19988
Homologene: 31001
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104401
Homologene: 17000
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76967
Homologene: 8839
Bicra
Name: BRD4 interacting chromatin remodeling complex associated protein
Synonyms: Gltscr1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243842
HGNC: HGNC:4332
Homologene: 9250
Eif5b
Name: eukaryotic translation initiation factor 5B
Synonyms: IF2, A030003E17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226982
Homologene: 134613
Pdgfd
Name: platelet-derived growth factor, D polypeptide
Synonyms: 1110003I09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71785
VEGA: 9
Homologene: 11875
Tmprss4
Name: transmembrane protease, serine 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214523
Homologene: 80930
Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Synonyms: capsaicin receptor, VR-1, OTRPC1, Vr1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 193034
Homologene: 12920
Gnb1l
Name: guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Synonyms: Wdvcf, ESTM55, Wdr14, Me49f07
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13972
HGNC: HGNC:4397
Homologene: 41515
Scnn1g
Name: sodium channel, nonvoltage-gated 1 gamma
Synonyms: ENaC gamma
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20278
Homologene: 20280
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 665700
Homologene: 90772
Ldb3
Name: LIM domain binding 3
Synonyms: ZASP, cypher
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 24131
VEGA: 14
Homologene: 134626
Txnip
Name: thioredoxin interacting protein
Synonyms: THIF, VDUP1, mVDUP1, Hyplip1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56338
Homologene: 38186
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: B930001P07Rik, 6330504P12Rik, MLSN2, melastatin 2, LTRPC3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226025
VEGA: 19
Homologene: 62287
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20272
Homologene: 55706
Trpv2
Name: transient receptor potential cation channel, subfamily V, member 2
Synonyms: Vrl1, OTRPC2, VRL-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22368
Homologene: 7993
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70417
Homologene: 23771
Aste1
Name: asteroid homolog 1
Synonyms: 1100001A21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66595
Homologene: 130666
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Abcb11
Name: ATP-binding cassette, sub-family B member 11
Synonyms: PFIC2, ABC16, PGY4, Lith1, sister of P-glycoprotein, Bsep
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27413
HGNC: HGNC:42
Homologene: 74509
Il25
Name: interleukin 25
Synonyms: IL-17E, Il17e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 140806
VEGA: 14
Homologene: 15429
Cdhr2
Name: cadherin-related family member 2
Synonyms: LOC268663, Pcdh24
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268663
Homologene: 134510
Cfap96
Name: cilia and flagella associated protein 96
Synonyms: 1700029J07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69479
Homologene: 45977
Ccdc27
Name: coiled-coil domain containing 27
Synonyms: LOC381580
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381580
Homologene: 17596
Cdh24
Name: cadherin-like 24
Synonyms: cadherin 14-like, EY-cadherin, 1700040A22Rik, ENSMUSG00000022188
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239096
VEGA: 14
Homologene: 56951
Slc24a1
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214111
VEGA: 9
Homologene: 3472
Dglucy
Name: D-glutamate cyclase
Synonyms: 9030617O03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217830
Homologene: 11798
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627743
Homologene: 129680
Or8a1
Name: olfactory receptor family 8 subfamily A member 1
Synonyms: M71, GA_x6K02T2PVTD-31408136-31407207, MOR171-2, Olfr151
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 406176
HGNC: HGNC:8469
Homologene: 12726
Fbln2
Name: fibulin 2
Synonyms: 5730577E14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14115
HGNC: HGNC:3601
Homologene: 1514
Cpb1
Name: carboxypeptidase B1
Synonyms: 2210008M23Rik, 0910001A18Rik, 1810063F02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76703
HGNC: HGNC:2299
Homologene: 68127
Vmn1r61
Name: vomeronasal 1 receptor 61
Synonyms: Gm7186
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 636731
Homologene: 41799
Ssbp2
Name: single-stranded DNA binding protein 2
Synonyms: Hspc116, 2310079I02Rik, 9330163K02Rik, 1500004K09Rik, A830008M03Rik, Ssdp2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66970
Homologene: 22724
Cpvl
Name: carboxypeptidase, vitellogenic-like
Synonyms: 4933436L16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71287
Homologene: 80235
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Abcc1
Name: ATP-binding cassette, sub-family C member 1
Synonyms: MRP, Mdrap, Mrp1, Abcc1b, Abcc1a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Zyg11b
Name: zyg-ll family member B, cell cycle regulator
Synonyms: LOC242610, 1110046I03Rik, D4Mgi23, 2810482G21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 414872
Homologene: 14600
Xkr5
Name: X-linked Kx blood group related 5
Synonyms: 5430438H03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319581
Homologene: 52219
Cyp2u1
Name: cytochrome P450, family 2, subfamily u, polypeptide 1
Synonyms: 8430436A10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71519
Homologene: 77704
H6pd
Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms: Gpd-1, Gpd1, G6pd1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100198
HGNC: HGNC:4795
Homologene: 48275
Tmprss11d
Name: transmembrane protease, serine 11d
Synonyms: AsP
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231382
Homologene: 74519
Lrrc23
Name: leucine rich repeat containing 23
Synonyms: 4921537K05Rik, Lrpb7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16977
Homologene: 5082
Pknox2
Name: Pbx/knotted 1 homeobox 2
Synonyms: Prep2, D230005H23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208076
Homologene: 32527
Or6c2b
Name: olfactory receptor family 6 subfamily C member 2B
Synonyms: GA_x6K02T2PULF-10797876-10796938, MOR114-14, Olfr769
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 257667
Homologene: 121502
Col25a1
Name: collagen, type XXV, alpha 1
Synonyms: 2700062B08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77018
Homologene: 57111
Or12e8
Name: olfactory receptor family 12 subfamily E member 8
Synonyms: GA_x6K02T2Q125-48849180-48850100, MOR264-2, Olfr1120
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259031
Homologene: 72054
Retreg1
Name: reticulophagy regulator 1
Synonyms: 1810015C04Rik, Fam134b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66270
VEGA: 15
Homologene: 10368
Ikzf2
Name: IKAROS family zinc finger 2
Synonyms: Helios, Zfpn1a2, A730095J18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22779
Homologene: 22659
Trav6-1
Name: T cell receptor alpha variable 6-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 667449
Pou2af2
Name: POU domain, class 2, associating factor 2
Synonyms: OCA-B homolog, 1810046K07Rik, Oca-t1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69809
Homologene: 18881
Gja10
Name: gap junction protein, alpha 10
Synonyms: Cx-57, connexin-57, Cx59, Cx57
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14610
Homologene: 7733
Gm28042
Name: predicted gene, 28042
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102238433
Grem2
Name: gremlin 2, DAN family BMP antagonist
Synonyms: Prdc
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23893
Homologene: 8023
Ighv11-2
Name: immunoglobulin heavy variable V11-2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780818
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 26,683,958 bp
  • C to T, chromosome 1 at 33,779,140 bp
  • T to C, chromosome 1 at 38,050,306 bp
  • T to A, chromosome 1 at 69,539,385 bp
  • A to T, chromosome 1 at 174,837,119 bp
  • G to A, chromosome 2 at 31,420,830 bp
  • A to T, chromosome 2 at 35,296,421 bp
  • A to T, chromosome 2 at 52,220,221 bp
  • C to T, chromosome 2 at 66,757,230 bp
  • C to T, chromosome 2 at 69,277,802 bp
  • T to C, chromosome 2 at 87,358,253 bp
  • A to G, chromosome 2 at 120,039,957 bp
  • T to C, chromosome 2 at 156,077,937 bp
  • A to G, chromosome 3 at 20,270,324 bp
  • T to C, chromosome 3 at 96,560,223 bp
  • G to T, chromosome 3 at 130,584,701 bp
  • A to C, chromosome 3 at 131,297,947 bp
  • G to T, chromosome 4 at 19,627,660 bp
  • T to A, chromosome 4 at 32,602,058 bp
  • A to G, chromosome 4 at 83,473,038 bp
  • T to C, chromosome 4 at 108,266,458 bp
  • T to A, chromosome 4 at 149,982,636 bp
  • T to C, chromosome 4 at 154,032,967 bp
  • A to G, chromosome 5 at 86,326,450 bp
  • G to T, chromosome 5 at 120,624,724 bp
  • C to G, chromosome 5 at 121,208,528 bp
  • A to T, chromosome 5 at 135,733,644 bp
  • T to A, chromosome 5 at 143,991,583 bp
  • A to T, chromosome 5 at 150,723,337 bp
  • T to A, chromosome 6 at 53,947,742 bp
  • T to A, chromosome 6 at 91,265,863 bp
  • G to T, chromosome 6 at 122,581,562 bp
  • T to A, chromosome 6 at 124,779,112 bp
  • A to T, chromosome 7 at 5,610,768 bp
  • T to C, chromosome 7 at 15,989,442 bp
  • A to G, chromosome 7 at 98,615,555 bp
  • T to A, chromosome 7 at 121,763,434 bp
  • C to A, chromosome 8 at 18,933,592 bp
  • A to G, chromosome 8 at 45,962,294 bp
  • A to G, chromosome 8 at 85,055,034 bp
  • A to G, chromosome 9 at 6,359,739 bp
  • A to G, chromosome 9 at 7,124,855 bp
  • A to T, chromosome 9 at 9,970,565 bp
  • A to G, chromosome 9 at 36,954,831 bp
  • A to G, chromosome 9 at 37,730,687 bp
  • A to G, chromosome 9 at 45,175,555 bp
  • C to A, chromosome 9 at 51,290,060 bp
  • A to G, chromosome 9 at 64,924,482 bp
  • A to G, chromosome 9 at 96,297,642 bp
  • T to A, chromosome 9 at 105,402,705 bp
  • A to T, chromosome 10 at 3,957,491 bp
  • A to C, chromosome 10 at 75,160,330 bp
  • A to G, chromosome 10 at 91,054,380 bp
  • T to A, chromosome 10 at 127,064,237 bp
  • G to T, chromosome 10 at 129,111,736 bp
  • T to C, chromosome 11 at 62,589,750 bp
  • G to A, chromosome 11 at 72,759,943 bp
  • C to T, chromosome 11 at 73,238,529 bp
  • G to A, chromosome 11 at 101,200,900 bp
  • T to A, chromosome 12 at 71,150,405 bp
  • C to T, chromosome 12 at 73,982,511 bp
  • C to A, chromosome 12 at 100,857,051 bp
  • A to G, chromosome 12 at 112,785,021 bp
  • T to C, chromosome 12 at 114,048,358 bp
  • T to C, chromosome 13 at 54,717,915 bp
  • T to A, chromosome 13 at 91,675,090 bp
  • T to A, chromosome 14 at 34,567,445 bp
  • A to C, chromosome 14 at 52,638,515 bp
  • T to C, chromosome 14 at 54,632,180 bp
  • A to G, chromosome 14 at 54,933,002 bp
  • G to T, chromosome 15 at 25,889,542 bp
  • A to T, chromosome 15 at 64,120,125 bp
  • G to A, chromosome 16 at 14,389,899 bp
  • C to A, chromosome 16 at 18,540,470 bp
  • A to G, chromosome 17 at 20,208,783 bp
  • G to A, chromosome 18 at 10,122,762 bp
  • T to C, chromosome 18 at 34,824,881 bp
  • A to G, chromosome 18 at 57,191,115 bp
  • G to A, chromosome 19 at 5,667,459 bp
  • T to C, chromosome 19 at 22,978,573 bp
  • C to T, chromosome 19 at 29,298,383 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7488 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045562-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.