Strain Name:
C57BL/6J-MtgxR7577Btlr/Mmmh
Stock Number:
045662-MU
Citation ID:
RRID:MMRRC_045662-MU
Other Names:
R7577 (G1)
Major Collection:

Strain Information

Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56531
Homologene: 87707
Spred1
Name: sprouty protein with EVH-1 domain 1, related sequence
Synonyms: Spred-1, 5730461F13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 114715
Homologene: 24919
Fos
Name: FBJ osteosarcoma oncogene
Synonyms: c-fos, D12Rfj1, cFos
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14281
HGNC: HGNC:3796
Homologene: 3844
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: 53BP1, p53BP1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27223
Homologene: 4137
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: nonmuscle myosin heavy chain II-B, NMHC-B, SMemb, nonmuscle myosin heavy chain IIB, 9330167F11Rik, 5730504C04Rik, NMHC II-B, Myhn2, Myosin IIB, Myhn-2, myosin IIB, Fltn, Fltn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Prmt7
Name: protein arginine N-methyltransferase 7
Synonyms: 4933402B05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 214572
Homologene: 10382
Akap9
Name: A kinase anchor protein 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Ensa
Name: endosulfine alpha
Synonyms: 1700020C18Rik, 2610007F17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56205
HGNC: HGNC:3360
Homologene: 37924
Git2
Name: GIT ArfGAP 2
Synonyms: Cool associated tyrosine phosphorylated-2, Cat-2, ARF GTPase activating protein 2, 5830420E16Rik, B230104M05Rik, 1500036H07Rik, 9630056M03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26431
HGNC: HGNC:4273
Homologene: 41336
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, Ankyrin-3, AnkG, 2900054D09Rik, Ankyrin-G
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Dlx6
Name: distal-less homeobox 6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13396
HGNC: HGNC:2919
Homologene: 87855
Azin1
Name: antizyme inhibitor 1
Synonyms: ODC antizyme inhibitor, Oazi, 1700085L02Rik, Oazin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54375
Homologene: 22933
Rnf123
Name: ring finger protein 123
Synonyms: KPC1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 84585
Homologene: 11112
Hnrnpd
Name: heterogeneous nuclear ribonucleoprotein D
Synonyms: Auf1, Hnrpd
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11991
HGNC: HGNC:5036
Homologene: 22410
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: nesprin-1, SYNE-1, enaptin165, A330049M09Rik, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Rad23a
Name: RAD23 homolog A, nucleotide excision repair protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19358
HGNC: HGNC:9812
Homologene: 48322
B3galt2
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26878
HGNC: HGNC:917
Homologene: 74512
Zdhhc18
Name: zinc finger, DHHC domain containing 18
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 503610
Homologene: 110918
Furin
Name: furin, paired basic amino acid cleaving enzyme
Synonyms: Fur, PACE, SPC1, Pcsk3, 9130404I01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18550
HGNC: HGNC:8568
Homologene: 1930
Syt14
Name: synaptotagmin XIV
Synonyms: B230320I09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329324
Homologene: 17719
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Adss2
Name: adenylosuccinate synthase 2
Synonyms: AS, Adss
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11566
HGNC: HGNC:292
Homologene: 875
Vps11
Name: VPS11, CORVET/HOPS core subunit
Synonyms: 1200011A11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71732
VEGA: 9
Homologene: 6673
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 386750
Homologene: 8955
Ddx21
Name: DExD box helicase 21
Synonyms: RH II/Gu, RH-II/Gualpha, D10Ertd645e, D10Wsu42e, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56200
VEGA: 10
HGNC: HGNC:2744
Homologene: 3473
2610008E11Rik
Name: RIKEN cDNA 2610008E11 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72128
Homologene: 86705
Marchf7
Name: membrane associated ring-CH-type finger 7
Synonyms: Axot, Gtrgeo17, March7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57438
Homologene: 10753
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54403
Homologene: 55776
Nr1h2
Name: nuclear receptor subfamily 1, group H, member 2
Synonyms: RIP15, LXRbeta, LXRB, Unr2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22260
HGNC: HGNC:7965
Homologene: 21397
Lct
Name: lactase
Synonyms: LOC226413, Lphl, LPH
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226413
HGNC: HGNC:6530
Homologene: 124204
Tespa1
Name: thymocyte expressed, positive selection associated 1
Synonyms: A430001F24Rik, 5830405N20Rik, Itprid3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67596
VEGA: 10
Homologene: 106645
Mccc1
Name: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Synonyms: MCCalpha, MCCA, 1810045E08Rik, 2310058B18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72039
HGNC: HGNC:6936
Homologene: 10603
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: 9430028L06Rik, 9030411M15Rik, Fam38b2, Piezo2, Fam38b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, Abc10, D430003I15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102075
Homologene: 18516
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: A530024P18Rik, 2310008C07Rik, 2310003D02Rik, mXin beta, myomaxin, Cmya3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241431
Homologene: 19388
Gpld1
Name: glycosylphosphatidylinositol specific phospholipase D1
Synonyms: 6330541J12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14756
HGNC: HGNC:4459
Homologene: 1152
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: LOC381663, A330009G12Rik, Sec63d1, Mer3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330149
Homologene: 87103
Enkur
Name: enkurin, TRPC channel interacting protein
Synonyms: 4933434I06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71233
Homologene: 17022
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Ptafr
Name: platelet-activating factor receptor
Synonyms: PAFR, PAF receptor
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19204
HGNC: HGNC:9582
Homologene: 20260
Dpp7
Name: dipeptidylpeptidase 7
Synonyms: QPP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 83768
Homologene: 22748
Prkce
Name: protein kinase C, epsilon
Synonyms: PKC[e], Pkce, 5830406C15Rik, PKCepsilon, PCK epsilon
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18754
HGNC: HGNC:9401
Homologene: 48343
Ptprn2
Name: protein tyrosine phosphatase receptor type N polypeptide 2
Synonyms: PTP-NP, IA-2 beta, phogrin, IA-2beta, 4930425H11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Unc5d
Name: unc-5 netrin receptor D
Synonyms: Unc5h4, D930029E11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210801
Homologene: 15450
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Dclre1a
Name: DNA cross-link repair 1A
Synonyms: mSNM1, SNM1, 2810043H12Rik, SMN1a
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 55947
Homologene: 8920
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226250
Homologene: 13057
Gmip
Name: Gem-interacting protein
Synonyms: 5031419I10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78816
Homologene: 9570
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18080
Homologene: 40632
Vmn1r235
Name: vomeronasal 1 receptor 235
Synonyms: V1rf2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171233
Homologene: 74360
Tmem268
Name: transmembrane protein 268
Synonyms: 6330416G13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230279
Homologene: 17005
Foxs1
Name: forkhead box S1
Synonyms: FREAC10, Fkh3, Fkhl18
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14239
HGNC: HGNC:3735
Homologene: 20871
Ankfn1
Name: ankyrin-repeat and fibronectin type III domain containing 1
Synonyms: LOC382543, nmf9, 4932411E22Rik, mWAKE
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 382543
Homologene: 34996
Man1c1
Name: mannosidase, alpha, class 1C, member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230815
Homologene: 69303
Wipf3
Name: WAS/WASL interacting protein family, member 3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330319
Homologene: 113391
Niban1
Name: niban apoptosis regulator 1
Synonyms: Niban, Fam129a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 63913
Homologene: 62170
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244418
Homologene: 18256
Sfxn4
Name: sideroflexin 4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94281
Homologene: 14228
Gbp10
Name: guanylate-binding protein 10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 626578
Homologene: 128731
Plcd1
Name: phospholipase C, delta 1
Synonyms: PLC-delta 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18799
VEGA: 9
HGNC: HGNC:9060
Homologene: 21252
Atpsckmt
Name: ATP synthase C subunit lysine N-methyltransferase
Synonyms: A930016P21Rik, Fam173b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68073
Homologene: 16780
Potegl
Name: POTE ankyrin domain family, member G like
Synonyms: 4931423N10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70981
Homologene: 86765
Zfp760
Name: zinc finger protein 760
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240034
VEGA: 17
Prima1
Name: proline rich membrane anchor 1
Synonyms: B230212M13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 170952
Homologene: 15783
Ero1b
Name: endoplasmic reticulum oxidoreductase 1 beta
Synonyms: 1700065B09Rik, 1300013B24Rik, Ero1lb
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67475
VEGA: 13
Homologene: 8740
Csn3
Name: casein kappa
Synonyms: CSN10, Csnk
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12994
HGNC: HGNC:2446
Homologene: 3818
Cxcr2
Name: C-X-C motif chemokine receptor 2
Synonyms: CD128, IL-8Rh, IL-8rb, Gpcr16, IL8RA, Cmkar2, Il8rb
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12765
HGNC: HGNC:6027
Homologene: 10439
Krt32
Name: keratin 32
Synonyms: mHa2, Krt1-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16670
HGNC: HGNC:6449
Homologene: 68246
Tox2
Name: TOX high mobility group box family member 2
Synonyms: RxHMG1, LOC269389
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269389
Homologene: 13155
Afg1l
Name: AFG1 like ATPase
Synonyms: Lace1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215951
Homologene: 5782
Cnbd2
Name: cyclic nucleotide binding domain containing 2
Synonyms: 5430421B09Rik, 4921517L17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70873
Homologene: 15440
Dnajb14
Name: DnaJ heat shock protein family (Hsp40) member B14
Synonyms: 5730496F10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70604
Homologene: 57015
Grin2d
Name: glutamate receptor, ionotropic, NMDA2D (epsilon 4)
Synonyms: NMDAR2D, NR2D, GluRepsilon4, GluN2D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14814
HGNC: HGNC:4588
Homologene: 648
Or5k15
Name: olfactory receptor family 5 subfamily J member 15
Synonyms: GA_x54KRFPKG5P-55108059-55107100, MOR184-6, Olfr178
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258999
Homologene: 79412
Pnma2
Name: paraneoplastic antigen MA2
Synonyms: A830049P17Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239157
HGNC: HGNC:9159
Homologene: 5249
Or4g7
Name: olfactory receptor family 4 subfamily G member 7
Synonyms: GA_x6K02T2Q125-72530279-72531217, MOR245-9, Olfr1288
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258395
Homologene: 88360
Fbxo3
Name: F-box protein 3
Synonyms: Fba, 1700026K02Rik, 1200002G09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57443
Homologene: 8133
Tysnd1
Name: trypsin domain containing 1
Synonyms: 1300019N10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71767
VEGA: 10
Homologene: 87946
Tmem52b
Name: transmembrane protein 52B
Synonyms: D630042F21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330428
Homologene: 27407
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 74,158,915 bp
  • T to G, chromosome 1 at 128,300,732 bp
  • T to C, chromosome 1 at 143,647,304 bp
  • T to A, chromosome 1 at 151,718,312 bp
  • G to A, chromosome 1 at 177,767,697 bp
  • T to C, chromosome 1 at 192,983,577 bp
  • C to T, chromosome 2 at 21,205,102 bp
  • A to G, chromosome 2 at 23,207,825 bp
  • A to G, chromosome 2 at 25,355,591 bp
  • T to A, chromosome 2 at 60,229,704 bp
  • G to A, chromosome 2 at 67,514,965 bp
  • T to C, chromosome 2 at 104,051,198 bp
  • T to A, chromosome 2 at 111,479,132 bp
  • T to A, chromosome 2 at 117,177,325 bp
  • T to G, chromosome 2 at 121,236,638 bp
  • C to T, chromosome 2 at 152,932,441 bp
  • G to T, chromosome 2 at 156,328,376 bp
  • C to A, chromosome 2 at 163,315,902 bp
  • C to T, chromosome 3 at 35,975,794 bp
  • T to G, chromosome 3 at 73,051,115 bp
  • C to A, chromosome 3 at 95,628,645 bp
  • A to G, chromosome 3 at 122,174,014 bp
  • T to C, chromosome 3 at 137,904,797 bp
  • G to T, chromosome 4 at 63,562,444 bp
  • A to G, chromosome 4 at 132,579,752 bp
  • G to T, chromosome 4 at 133,615,209 bp
  • A to G, chromosome 4 at 134,564,503 bp
  • C to G, chromosome 5 at 3,968,745 bp
  • T to C, chromosome 5 at 87,929,962 bp
  • A to G, chromosome 5 at 89,225,867 bp
  • A to T, chromosome 5 at 99,967,254 bp
  • G to A, chromosome 5 at 105,236,149 bp
  • T to C, chromosome 5 at 106,896,043 bp
  • C to T, chromosome 5 at 114,766,489 bp
  • A to G, chromosome 6 at 6,863,423 bp
  • A to G, chromosome 6 at 54,485,524 bp
  • A to G, chromosome 6 at 85,615,320 bp
  • T to A, chromosome 6 at 129,516,077 bp
  • A to G, chromosome 7 at 28,154,423 bp
  • G to A, chromosome 7 at 44,550,792 bp
  • T to C, chromosome 7 at 45,862,379 bp
  • C to A, chromosome 7 at 46,287,855 bp
  • T to C, chromosome 7 at 80,396,986 bp
  • T to C, chromosome 8 at 28,891,421 bp
  • A to G, chromosome 8 at 36,146,942 bp
  • A to G, chromosome 8 at 69,814,435 bp
  • A to T, chromosome 8 at 84,838,479 bp
  • T to A, chromosome 8 at 105,375,399 bp
  • A to G, chromosome 8 at 106,242,203 bp
  • A to T, chromosome 9 at 44,348,961 bp
  • A to T, chromosome 9 at 105,864,688 bp
  • A to T, chromosome 9 at 108,070,619 bp
  • A to T, chromosome 9 at 119,072,254 bp
  • T to A, chromosome 10 at 5,124,820 bp
  • T to C, chromosome 10 at 42,318,611 bp
  • T to C, chromosome 10 at 61,695,886 bp
  • T to C, chromosome 10 at 62,590,670 bp
  • C to T, chromosome 10 at 69,992,572 bp
  • C to T, chromosome 10 at 79,066,491 bp
  • T to A, chromosome 10 at 81,880,189 bp
  • T to A, chromosome 10 at 88,549,325 bp
  • T to C, chromosome 10 at 130,354,755 bp
  • T to A, chromosome 11 at 68,745,980 bp
  • T to A, chromosome 11 at 89,503,971 bp
  • T to A, chromosome 11 at 100,081,221 bp
  • T to C, chromosome 12 at 70,062,706 bp
  • T to A, chromosome 12 at 84,997,220 bp
  • T to C, chromosome 12 at 85,475,097 bp
  • T to C, chromosome 12 at 103,197,307 bp
  • T to C, chromosome 12 at 116,485,866 bp
  • T to G, chromosome 13 at 12,602,365 bp
  • A to G, chromosome 13 at 24,962,405 bp
  • A to G, chromosome 14 at 66,915,979 bp
  • C to T, chromosome 15 at 31,606,040 bp
  • C to T, chromosome 15 at 38,501,421 bp
  • G to T, chromosome 16 at 58,889,266 bp
  • A to G, chromosome 17 at 21,261,619 bp
  • T to A, chromosome 17 at 21,722,261 bp
  • C to A, chromosome 17 at 86,493,293 bp
  • G to T, chromosome 18 at 63,053,010 bp
  • A to G, chromosome 19 at 56,529,533 bp
  • T to C, chromosome 19 at 56,944,767 bp
  • A to C, chromosome 19 at 60,853,886 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7577 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045662-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.