Strain Name:
C57BL/6J-MtgxR7640Btlr/Mmmh
Stock Number:
045698-MU
Citation ID:
RRID:MMRRC_045698-MU
Other Names:
R7640 (G1)
Major Collection:

Strain Information

Nts
Name: neurotensin
Synonyms: 5033428E16Rik, NMN-125, neuromedin N, NT/N, NTS1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67405
VEGA: 10
HGNC: HGNC:8038
Homologene: 4506
Cnmd
Name: chondromodulin
Synonyms: Lect1, Chmd, Chondromodulin 1, Bricd3, ChM-I
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16840
Homologene: 5095
Zfp423
Name: zinc finger protein 423
Synonyms: Zfp104, Roaz, Ebfaz, ataxia1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94187
Homologene: 9010
Mfap4
Name: microfibrillar-associated protein 4
Synonyms: 1110007F23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76293
HGNC: HGNC:7035
Homologene: 134529
Pmepa1
Name: prostate transmembrane protein, androgen induced 1
Synonyms: N4wbp4, Tmepai, STAG1, PMEPA1, 2210418I02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 65112
Homologene: 10608
Sema3f
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Synonyms: Sema IV, Semak
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20350
Homologene: 20885
En2
Name: engrailed 2
Synonyms: En-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13799
HGNC: HGNC:3343
Homologene: 55579
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: Mnab, 2900024N03Rik, D930043C02Rik, Rnf164, 9430019J22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319817
Homologene: 28276
Rlf
Name: rearranged L-myc fusion sequence
Synonyms: MommeD8, 9230110M18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109263
Homologene: 8243
Specc1l
Name: sperm antigen with calponin homology and coiled-coil domains 1-like
Synonyms: 4932439K10Rik, 9530057A13Rik, 4930470P14Rik, Specc1l, Cytsa
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74392
VEGA: 10
Homologene: 15610
Rpap1
Name: RNA polymerase II associated protein 1
Synonyms: 1190005L06Rik, A730023M06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68925
Homologene: 32269
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
L2hgdh
Name: L-2-hydroxyglutarate dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217666
VEGA: 12
Homologene: 11767
Mcph1
Name: microcephaly, primary autosomal recessive 1
Synonyms: 5430437K10Rik, D030046N04Rik, BRIT1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244329
HGNC: HGNC:6954
Homologene: 32586
Fas
Name: Fas cell surface death receptor
Synonyms: CD95, APO-1, Tnfrsf6, TNFR6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14102
VEGA: 19
Homologene: 27
Nat10
Name: N-acetyltransferase 10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98956
Homologene: 6785
Clock
Name: clock circadian regulator
Synonyms: bHLHe8, KAT13D, 5330400M04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117146
Homologene: 13775
Impdh2
Name: inosine monophosphate dehydrogenase 2
Synonyms: IMP dehydrogenase type II
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23918
HGNC: HGNC:6053
Homologene: 48919
Trim2
Name: tripartite motif-containing 2
Synonyms: neural activity-related ring finger protein, narf
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80890
Homologene: 22882
Eef1d
Name: eukaryotic translation elongation factor 1 delta
Synonyms: 1700026P12Rik, 5730529A16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66656
HGNC: HGNC:3211
Homologene: 23404
Armt1
Name: acidic residue methyltransferase 1
Synonyms: 1700052N19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 73419
Homologene: 41557
Dync2i2
Name: dynein 2 intermediate chain 2
Synonyms: 3200002I06Rik, Wdr34
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71820
Homologene: 14156
Ddx41
Name: DEAD box helicase 41
Synonyms: 2900024F02Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72935
VEGA: 13
Homologene: 9431
Cep72
Name: centrosomal protein 72
Synonyms: 4933440J22Rik, 2610029E11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 74470
VEGA: 13
Homologene: 10027
Ap3m1
Name: adaptor-related protein complex 3, mu 1 subunit
Synonyms: 1200013D09Rik, C78982
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 55946
HGNC: HGNC:569
Homologene: 22693
Golga2
Name: golgin A2
Synonyms: GM130
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99412
HGNC: HGNC:4425
Homologene: 3300
Abcb6
Name: ATP-binding cassette, sub-family B member 6
Synonyms: 1200005B17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74104
HGNC: HGNC:47
Homologene: 11375
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: C130041O22Rik, Zfh4, Zfh-4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Large2
Name: LARGE xylosyl- and glucuronyltransferase 2
Synonyms: Gyltl1b, 5730485C17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228366
Homologene: 27362
Plekhh2
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213556
VEGA: 17
Homologene: 35317
Drc3
Name: dynein regulatory complex subunit 3
Synonyms: Lrrc48, m6Bei, 4930449E07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74665
Homologene: 12581
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Otoa
Name: otoancorin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 246190
Homologene: 71803
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Tmem132c
Name: transmembrane protein 132C
Synonyms: 4632425D07Rik, 2810482M11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208213
Homologene: 76567
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: Lrrc22, A930010E21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239038
VEGA: 14
Homologene: 18292
Klhdc7b
Name: kelch domain containing 7B
Synonyms: EG546648
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 546648
Homologene: 34707
Ankrd42
Name: ankyrin repeat domain 42
Synonyms: Ikbn, 4933417L02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73845
Homologene: 23652
Mrc2
Name: mannose receptor, C type 2
Synonyms: novel lectin, uPARAP, Endo180
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17534
Homologene: 4408
Or5w11
Name: olfactory receptor family 5 subfamily W member 11
Synonyms: MOR177-4, Olfr1131, GA_x6K02T2Q125-49133664-49134593
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258652
Homologene: 133019
Or4a66
Name: olfactory receptor family 4 subfamily A member 66
Synonyms: MOR225-5, GA_x6K02T2Q125-50181139-50180195, Olfr1196
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258456
Homologene: 123770
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Cuta
Name: cutA divalent cation tolerance homolog
Synonyms: 1810022E02Rik, CutA, 1810060C03Rik, 2700094G22Rik, 0610039D01Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67675
VEGA: 17
Homologene: 9305
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: 4930544G21Rik, A930009L15Rik, SKIP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77629
Homologene: 18172
Zkscan7
Name: zinc finger with KRAB and SCAN domains 7
Synonyms: Zfp167
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382118
VEGA: 9
Homologene: 83284
Or8k30
Name: olfactory receptor family 8 subfamily K member 30
Synonyms: MOR189-2, Olfr1076, GA_x6K02T2Q125-47993761-47994702
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258401
Homologene: 17233
Rragd
Name: Ras-related GTP binding D
Synonyms: C030003H22Rik, 5730543C08Rik, D4Ertd174e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 52187
Homologene: 49667
Sp110
Name: Sp110 nuclear body protein
Synonyms: Ifi75, Ipr1, 52kDa, 5830484A20Rik, 5031415C07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
1700013G24Rik
Name: RIKEN cDNA 1700013G24 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69380
Homologene: 124477
Mrgprb5
Name: MAS-related GPR, member B5
Synonyms: MrgB5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404239
Homologene: 115575
Adamts14
Name: ADAM metallopeptidase with thrombospondin type 1 motif 14
Synonyms: Adamts-14, TS14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237360
Homologene: 16383
Or51k2
Name: olfactory receptor family 51 subfamily K member 2
Synonyms: MOR12-5, Olfr633, GA_x6K02T2PBJ9-6681230-6682168
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258351
Homologene: 27136
Mknk2
Name: MAP kinase-interacting serine/threonine kinase 2
Synonyms: 2010016G11Rik, Mnk2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17347
HGNC: HGNC:7111
Homologene: 49674
Zfp873
Name: zinc finger protein 873
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 408062
Homologene: 134319
Zfp850
Name: zinc finger protein 850
Synonyms: C130069I09Rik, Gm4636
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043772
Tbc1d21
Name: TBC1 domain family, member 21
Synonyms: 1700095K08Rik, MgcRabGAP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74286
VEGA: 9
Homologene: 14033
Dnajc22
Name: DnaJ heat shock protein family (Hsp40) member C22
Synonyms: 2810451A06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72778
Homologene: 11777
Ttc34
Name: tetratricopeptide repeat domain 34
Synonyms: B230396O12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242800
Homologene: 130480
Tlcd4
Name: TLC domain containing 4
Synonyms: Tmem56, 4930577M16Rik, C730036B01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99887
Homologene: 45107
Gprin2
Name: G protein regulated inducer of neurite outgrowth 2
Synonyms: C130040D06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 432839
VEGA: 14
Homologene: 40975
Mcee
Name: methylmalonyl CoA epimerase
Synonyms: 1110007A04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73724
Homologene: 13078
Mlf1
Name: myeloid leukemia factor 1
Synonyms: HLS7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 17349
HGNC: HGNC:7125
Homologene: 7839
Nscme3l
Name: NSE3 homolog, SMC5-SMC6 complex component like
Synonyms: 1700020D05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 75555
HGNC: HGNC:7677
Homologene: 137364
Oas1b
Name: 2'-5' oligoadenylate synthetase 1B
Synonyms: Mmu-L1, Oias2, L1, Oias-2, Wnv, Flavivirus resistance, Flv
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 23961
HGNC: HGNC:8086
Pcdhac2
Name: protocadherin alpha subfamily C, 2
Synonyms: CNRc2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 353237
HGNC: HGNC:8677
Homologene: 49562
4930558K02Rik
Name: RIKEN cDNA 4930558K02 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75368
Homologene: 51403
Ighv14-4
Name: immunoglobulin heavy variable 14-4
Synonyms: Gm16841
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629826
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 75,174,845 bp
  • C to T, chromosome 1 at 83,278,928 bp
  • G to A, chromosome 1 at 85,579,092 bp
  • A to T, chromosome 1 at 153,136,804 bp
  • A to G, chromosome 1 at 161,957,149 bp
  • T to G, chromosome 2 at 30,031,768 bp
  • T to C, chromosome 2 at 32,306,239 bp
  • A to G, chromosome 2 at 37,377,849 bp
  • A to G, chromosome 2 at 86,508,943 bp
  • A to G, chromosome 2 at 87,629,092 bp
  • T to A, chromosome 2 at 88,700,886 bp
  • T to C, chromosome 2 at 92,374,705 bp
  • G to A, chromosome 2 at 103,743,090 bp
  • G to A, chromosome 2 at 119,764,410 bp
  • C to T, chromosome 2 at 173,276,163 bp
  • T to C, chromosome 3 at 5,412,480 bp
  • G to A, chromosome 3 at 67,392,933 bp
  • C to A, chromosome 3 at 84,190,906 bp
  • A to G, chromosome 3 at 121,235,041 bp
  • A to T, chromosome 4 at 32,983,527 bp
  • T to A, chromosome 4 at 121,146,801 bp
  • A to T, chromosome 4 at 137,454,594 bp
  • T to C, chromosome 4 at 143,726,706 bp
  • A to G, chromosome 4 at 154,861,384 bp
  • A to T, chromosome 5 at 28,170,166 bp
  • G to T, chromosome 5 at 76,248,378 bp
  • A to G, chromosome 5 at 114,415,323 bp
  • T to C, chromosome 5 at 120,821,414 bp
  • A to G, chromosome 5 at 127,563,006 bp
  • T to C, chromosome 7 at 27,989,209 bp
  • T to G, chromosome 7 at 48,168,259 bp
  • T to A, chromosome 7 at 64,411,968 bp
  • A to G, chromosome 7 at 92,619,635 bp
  • A to T, chromosome 7 at 103,946,943 bp
  • A to G, chromosome 7 at 121,145,626 bp
  • T to A, chromosome 8 at 18,632,326 bp
  • T to C, chromosome 8 at 87,781,277 bp
  • C to T, chromosome 9 at 58,361,261 bp
  • T to G, chromosome 9 at 95,907,293 bp
  • A to T, chromosome 9 at 105,785,744 bp
  • A to T, chromosome 9 at 107,683,575 bp
  • T to C, chromosome 9 at 108,565,181 bp
  • A to G, chromosome 9 at 122,896,056 bp
  • T to C, chromosome 10 at 4,453,572 bp
  • C to A, chromosome 10 at 61,246,057 bp
  • T to A, chromosome 10 at 75,257,869 bp
  • T to C, chromosome 10 at 80,668,566 bp
  • T to C, chromosome 10 at 82,060,275 bp
  • T to A, chromosome 10 at 82,294,656 bp
  • T to C, chromosome 10 at 102,490,304 bp
  • A to G, chromosome 11 at 60,388,904 bp
  • A to G, chromosome 11 at 61,487,087 bp
  • T to A, chromosome 11 at 105,332,295 bp
  • A to T, chromosome 12 at 69,721,357 bp
  • A to T, chromosome 12 at 114,176,444 bp
  • A to T, chromosome 13 at 55,534,239 bp
  • G to A, chromosome 13 at 74,058,488 bp
  • T to C, chromosome 14 at 21,038,175 bp
  • G to T, chromosome 14 at 34,195,753 bp
  • T to C, chromosome 14 at 37,072,124 bp
  • T to A, chromosome 14 at 79,661,534 bp
  • C to A, chromosome 15 at 75,902,707 bp
  • G to T, chromosome 15 at 89,387,260 bp
  • A to G, chromosome 15 at 99,101,114 bp
  • C to A, chromosome 16 at 32,760,105 bp
  • C to T, chromosome 17 at 26,938,422 bp
  • A to G, chromosome 17 at 84,610,776 bp
  • T to C, chromosome 18 at 37,144,525 bp
  • T to A, chromosome 19 at 5,503,007 bp
  • A to G, chromosome 19 at 34,307,164 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7640 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045698-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.