Strain Name:
C57BL/6J-MtgxR7623Btlr/Mmmh
Stock Number:
045718-MU
Citation ID:
RRID:MMRRC_045718-MU
Other Names:
R7623 (G1)
Major Collection:

Strain Information

Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Mybl2
Name: myeloblastosis oncogene-like 2
Synonyms: Bmyb, B-Myb
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17865
HGNC: HGNC:7548
Homologene: 1847
Ccnb2
Name: cyclin B2
Synonyms: CycB2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12442
VEGA: 9
HGNC: HGNC:1580
Homologene: 74359
Zfr
Name: zinc finger RNA binding protein
Synonyms: C920030H05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22763
Homologene: 8009
Dph6
Name: diphthamine biosynthesis 6
Synonyms: 5730421E18Rik, Diphthine ammonia ligase, Atpbd4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66632
Homologene: 80244
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Lamb2
Name: laminin, beta 2
Synonyms: Lamb-2, Lams, npht
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Mc4r
Name: melanocortin 4 receptor
Synonyms: Fatboy, Pkcp
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17202
VEGA: 18
HGNC: HGNC:6932
Homologene: 4320
Gas8
Name: growth arrest specific 8
Synonyms: Gas11
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104346
HGNC: HGNC:4166
Homologene: 1135
Abcc5
Name: ATP-binding cassette, sub-family C member 5
Synonyms: Mrp5, Abcc5b, Abcc5a, 2900011L11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Galnt5
Name: polypeptide N-acetylgalactosaminyltransferase 5
Synonyms: ppGaNTase-T5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241391
HGNC: HGNC:4127
Homologene: 8733
Sos1
Name: SOS Ras/Rac guanine nucleotide exchange factor 1
Synonyms: 4430401P03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20662
VEGA: 17
Homologene: 4117
Acadvl
Name: acyl-Coenzyme A dehydrogenase, very long chain
Synonyms: VLCAD
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11370
HGNC: HGNC:92
Homologene: 5
Smap1
Name: small ArfGAP 1
Synonyms: 4921514B13Rik, 1700056O10Rik, 4921525H11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98366
Homologene: 134676
Wdr25
Name: WD repeat domain 25
Synonyms: B930090D16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 212198
VEGA: 12
Homologene: 56993
Vwc2
Name: von Willebrand factor C domain containing 2
Synonyms: A930041G11Rik, Brorin, cradin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319922
Homologene: 18542
Rpn1
Name: ribophorin I
Synonyms: Rpn-1, D6Wsu137e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 103963
Homologene: 2213
Bach1
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: 6230421P05Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12013
HGNC: HGNC:935
Homologene: 916
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20743
VEGA: 19
Homologene: 48482
Mis18bp1
Name: MIS18 binding protein 1
Synonyms: C79407
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217653
Homologene: 10147
Sec22a
Name: SEC22 homolog A, vesicle trafficking protein
Synonyms: 1810005C06Rik, Sec22l2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 317717
Homologene: 8246
Pak6
Name: p21 (RAC1) activated kinase 6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214230
Homologene: 23200
Slc16a4
Name: solute carrier family 16 (monocarboxylic acid transporters), member 4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229699
Homologene: 74529
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Tnfaip2
Name: tumor necrosis factor, alpha-induced protein 2
Synonyms: Tnfip2, Exoc3l3, M-sec
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21928
Homologene: 4583
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, 9430076A06Rik, D430038H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: A830096D10Rik, Bai3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Pde5a
Name: phosphodiesterase 5A, cGMP-specific
Synonyms: PDE5A1, Pde5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242202
HGNC: HGNC:8784
Homologene: 842
Zfp605
Name: zinc finger protein 605
Synonyms: A830023I12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 675812
Homologene: 52335
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Zfp790
Name: zinc finger protein 790
Synonyms: 6330581L23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233056
Homologene: 51695
Sdr16c6
Name: short chain dehydrogenase/reductase family 16C, member 6
Synonyms: 4833413O15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242286
Homologene: 135698
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Eeig1
Name: estrogen-induced osteoclastogenesis regulator 1
Synonyms: C230093N12Rik, Fam102a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98952
Homologene: 51943
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 192187
Homologene: 9035
Cdh24
Name: cadherin-like 24
Synonyms: cadherin 14-like, EY-cadherin, 1700040A22Rik, ENSMUSG00000022188
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239096
VEGA: 14
Homologene: 56951
Gmpr2
Name: guanosine monophosphate reductase 2
Synonyms: 5730544D12Rik, 1810008P16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105446
VEGA: 14
HGNC: HGNC:4377
Homologene: 22983
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22755
Homologene: 117959
Ppp3cc
Name: protein phosphatase 3, catalytic subunit, gamma isoform
Synonyms: PP2BA gamma, Calnc
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19057
VEGA: 14
HGNC: HGNC:9316
Homologene: 68475
Tmprss11f
Name: transmembrane protease, serine 11f
Synonyms: 4732406D01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243083
Homologene: 65356
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76645
Homologene: 124481
Or7e168
Name: olfactory receptor family 7 subfamily E member 168
Synonyms: GA_x6K02T2PVTD-13548326-13549255, MOR146-3, MOR146-10_p, Olfr859
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258519
Homologene: 134093
Vmn1r210
Name: vomeronasal 1 receptor 210
Synonyms: V1rh10
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171269
Homologene: 110880
Mcam
Name: melanoma cell adhesion molecule
Synonyms: s-endo, CD146, s-gicerin, 1-gicerin, Muc18
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 84004
HGNC: HGNC:6934
Homologene: 4742
Tex55
Name: testis expressed 55
Synonyms: 4930435E12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74663
Homologene: 17614
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 626596
Homologene: 75047
Ccdc8
Name: coiled-coil domain containing 8
Synonyms: ENSMUSG00000041117
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434130
Homologene: 49977
Ano2
Name: anoctamin 2
Synonyms: Tmem16b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243634
HGNC: HGNC:1183
Homologene: 23221
Rsbn1
Name: rosbin, round spermatid basic protein 1
Synonyms: Rsbp, C230004D03Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229675
Homologene: 10154
Ptprb
Name: protein tyrosine phosphatase receptor type B
Synonyms: 3230402H02Rik, VE-PTP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Abhd10
Name: abhydrolase domain containing 10
Synonyms: D230019K24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 213012
Homologene: 10173
Or4k44
Name: olfactory receptor family 4 subfamily K member 44
Synonyms: GA_x6K02T2Q125-72589785-72588847, MOR248-7, Olfr1294
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258887
Homologene: 74216
Tst
Name: thiosulfate sulfurtransferase, mitochondrial
Synonyms: Rhodanese
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22117
VEGA: 15
Homologene: 37759
Gtpbp6
Name: GTP binding protein 6 (putative)
Synonyms: pgpl, Pgbpll
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 107999
Homologene: 8157
Pp2d1
Name: protein phosphatase 2C-like domain containing 1
Synonyms: 4921523A10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 110332
VEGA: 17
Homologene: 16981
Rnf8
Name: ring finger protein 8
Synonyms: AIP37, 3830404E21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 58230
Homologene: 2944
Fuca1
Name: fucosidase, alpha-L- 1, tissue
Synonyms: Afuc, 0610006A03Rik, 9530055J05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71665
HGNC: HGNC:4006
Homologene: 20078
Hemgn
Name: hemogen
Synonyms: EDAG, 4921524M03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 93966
Homologene: 14223
Hdhd5
Name: haloacid dehalogenase like hydrolase domain containing 5
Synonyms: A930002G03Rik, Cecr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 214932
HGNC: HGNC:1843
Homologene: 32816
2510009E07Rik
Name: RIKEN cDNA 2510009E07 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72190
VEGA: 16
Homologene: 78167
Gja5
Name: gap junction protein, alpha 5
Synonyms: connexin 40, Cx40, Gja-5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14613
HGNC: HGNC:4279
Homologene: 3856
H2bc22
Name: H2B clustered histone 22
Synonyms: Hist1h2bp
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319188
HGNC: HGNC:4758
Homologene: 134442
Fbxw25
Name: F-box and WD-40 domain protein 25
Synonyms: E330001B16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 546160
Hoxa1
Name: homeobox A1
Synonyms: ERA1, early retinoic acid, Hox-1.6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15394
HGNC: HGNC:5099
Homologene: 4032
Dact3
Name: dishevelled-binding antagonist of beta-catenin 3
Synonyms: EG666671
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629378
Homologene: 77340
Iglc1
Name: immunoglobulin lambda constant 1
Synonyms: Clambda1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110785
Trav6d-5
Name: T cell receptor alpha variable 6D-5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 667481
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 23,848,295 bp
  • T to A, chromosome 1 at 25,547,548 bp
  • T to A, chromosome 1 at 34,170,436 bp
  • A to G, chromosome 2 at 32,566,334 bp
  • A to G, chromosome 2 at 58,017,210 bp
  • T to C, chromosome 2 at 111,537,936 bp
  • C to A, chromosome 2 at 114,654,898 bp
  • A to G, chromosome 2 at 118,694,587 bp
  • A to G, chromosome 2 at 163,072,832 bp
  • A to G, chromosome 2 at 177,508,612 bp
  • T to C, chromosome 3 at 97,050,755 bp
  • A to T, chromosome 3 at 103,915,010 bp
  • G to A, chromosome 3 at 107,297,981 bp
  • A to G, chromosome 3 at 122,774,601 bp
  • T to A, chromosome 4 at 4,058,801 bp
  • A to G, chromosome 4 at 46,396,504 bp
  • A to G, chromosome 4 at 135,933,094 bp
  • C to T, chromosome 5 at 86,524,160 bp
  • T to A, chromosome 5 at 110,105,084 bp
  • A to G, chromosome 5 at 110,127,520 bp
  • T to G, chromosome 6 at 52,158,258 bp
  • T to C, chromosome 6 at 88,084,568 bp
  • T to C, chromosome 6 at 120,521,251 bp
  • T to A, chromosome 6 at 126,015,573 bp
  • C to A, chromosome 7 at 16,885,915 bp
  • T to A, chromosome 7 at 16,996,612 bp
  • T to C, chromosome 7 at 24,276,369 bp
  • T to A, chromosome 7 at 29,825,705 bp
  • T to A, chromosome 7 at 131,277,566 bp
  • T to C, chromosome 7 at 139,618,350 bp
  • A to T, chromosome 8 at 95,727,648 bp
  • A to T, chromosome 8 at 117,029,645 bp
  • G to T, chromosome 8 at 123,522,979 bp
  • T to A, chromosome 9 at 15,988,324 bp
  • A to T, chromosome 9 at 19,808,929 bp
  • T to A, chromosome 9 at 44,139,658 bp
  • A to G, chromosome 9 at 70,418,888 bp
  • C to T, chromosome 9 at 108,489,224 bp
  • T to C, chromosome 9 at 109,654,583 bp
  • A to C, chromosome 10 at 116,369,309 bp
  • T to C, chromosome 11 at 11,116,415 bp
  • G to T, chromosome 11 at 70,010,743 bp
  • T to C, chromosome 11 at 110,107,558 bp
  • A to G, chromosome 12 at 65,148,852 bp
  • G to A, chromosome 12 at 108,992,893 bp
  • A to G, chromosome 12 at 111,445,638 bp
  • T to A, chromosome 13 at 21,787,592 bp
  • A to T, chromosome 13 at 22,827,235 bp
  • A to G, chromosome 13 at 81,422,225 bp
  • C to A, chromosome 14 at 31,140,621 bp
  • A to G, chromosome 14 at 52,795,386 bp
  • A to T, chromosome 14 at 54,638,090 bp
  • G to A, chromosome 14 at 55,673,034 bp
  • A to C, chromosome 14 at 70,240,945 bp
  • C to T, chromosome 15 at 12,160,528 bp
  • A to T, chromosome 15 at 36,040,710 bp
  • A to G, chromosome 15 at 47,949,938 bp
  • G to A, chromosome 15 at 78,405,703 bp
  • T to A, chromosome 16 at 19,061,801 bp
  • C to T, chromosome 16 at 20,344,696 bp
  • G to T, chromosome 16 at 21,694,342 bp
  • A to G, chromosome 16 at 35,329,524 bp
  • C to T, chromosome 16 at 38,828,091 bp
  • A to G, chromosome 16 at 45,732,736 bp
  • G to A, chromosome 16 at 87,719,291 bp
  • T to A, chromosome 17 at 29,629,006 bp
  • T to C, chromosome 17 at 53,515,879 bp
  • A to T, chromosome 17 at 80,479,894 bp
  • T to C, chromosome 18 at 66,859,509 bp
  • A to G, chromosome 19 at 4,726,168 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7623 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045718-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.