Strain Name:
C57BL/6J-MtgxR7892Btlr/Mmmh
Stock Number:
045944-MU
Citation ID:
RRID:MMRRC_045944-MU
Other Names:
R7892 (G1)
Major Collection:

Strain Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: HALR, E330008K23Rik, Mll3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Dtnbp1
Name: dystrobrevin binding protein 1
Synonyms: Bloc1s8, 5430437B18Rik, dysbindin, sdy
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94245
VEGA: 13
Homologene: 12037
Trim59
Name: tripartite motif-containing 59
Synonyms: Mrf1, 2700022F13Rik, TSBF1, 2310035M22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66949
Homologene: 32644
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: E430014N10Rik, NBCn1, NBC3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Kif5b
Name: kinesin family member 5B
Synonyms: Khc, kinesin heavy chain
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16573
HGNC: HGNC:6324
Homologene: 55829
Malt1
Name: MALT1 paracaspase
Synonyms: paracaspase, D430033E09Rik, Pcasp1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240354
HGNC: HGNC:6819
Homologene: 4938
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230249
Homologene: 6056
Pgrmc2
Name: progesterone receptor membrane component 2
Synonyms: DG6, 5730409G06Rik, 4631434O19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70804
Homologene: 38169
Tubb4a
Name: tubulin, beta 4A class IVA
Synonyms: Tubb, Tubb4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22153
VEGA: 17
Homologene: 55952
Pcdh20
Name: protocadherin 20
Synonyms: PCDH13, C630015B17Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219257
Homologene: 11277
Ppm1m
Name: protein phosphatase 1M
Synonyms: PP2C eta, 2810423O19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67905
Homologene: 44900
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408066
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E21Rik, Myospryn, 2310076E16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Zc3hav1
Name: zinc finger CCCH type, antiviral 1
Synonyms: 1200014N16Rik, 9130009D18Rik, 9830115L13Rik, ZAP, 2900058M19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78781
Homologene: 10585
Sntg1
Name: syntrophin, gamma 1
Synonyms: G1SYN, SYN4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71096
Homologene: 56834
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Kif9
Name: kinesin family member 9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16578
Homologene: 65620
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 211223
Homologene: 129606
Adamts3
Name: ADAM metallopeptidase with thrombospondin type 1 motif 3
Synonyms: 6330442E02Rik, 1100001H14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Treh
Name: trehalase (brush-border membrane glycoprotein)
Synonyms: 2210412M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 58866
Homologene: 5198
Vmn2r70
Name: vomeronasal 2, receptor 70
Synonyms: EG620835
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670940
Homologene: 115466
Sik2
Name: salt inducible kinase 2
Synonyms: Snf1lk2, G630080D20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235344
Homologene: 22875
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Ces2b
Name: carboxyesterase 2B
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234669
HGNC: HGNC:1864
Homologene: 135851
Arhgef4
Name: Rho guanine nucleotide exchange factor 4
Synonyms: 9330140K16Rik, C230030N03Rik, Asef
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Speg
Name: SPEG complex locus
Synonyms: D1Bwg1450e, BPEG, Apeg1, SPEG, SPEGalpha, SPEGbeta
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11790
Homologene: 55619
Or10d1
Name: olfactory receptor family 10 subfamily D member 1
Synonyms: Olfr959, GA_x6K02T2PVTD-33270211-33269276, MOR224-3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258501
VEGA: 9
Homologene: 71989
Mylk
Name: myosin, light polypeptide kinase
Synonyms: MLCK210, 9530072E15Rik, nmMlck, telokin, Mlck, MLCK108, A930019C19Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12722
HGNC: HGNC:2017
Homologene: 77224
Or5b116
Name: olfactory receptor family 5 subfamily B member 116
Synonyms: Olfr1471, GA_x6K02T2RE5P-3777626-3778570, MOR202-47_p, MOR202-38
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258231
Homologene: 79417
Zfp558
Name: zinc finger protein 558
Synonyms: Zfp558-ps, 1700007A21Rik, 4932704I17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72230
Homologene: 44903
Vmn2r68
Name: vomeronasal 2, receptor 68
Synonyms: EG620697, Vmn2r68-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620697
Homologene: 115466
Or5b21
Name: olfactory receptor family 5 subfamily B member 21
Synonyms: MOR202-4, GA_x6K02T2RE5P-3191201-3192160, Olfr1444
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258697
Homologene: 64906
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Samhd1
Name: SAM domain and HD domain, 1
Synonyms: E330031J07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56045
Homologene: 9160
Fbxl9
Name: F-box and leucine-rich repeat protein 9
Synonyms: A630024J02Rik, FBL9, Lrrc29
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234684
Homologene: 133339
Oacyl
Name: O-acyltransferase like
Synonyms: 5330437I02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319888
Homologene: 129774
A630010A05Rik
Name: RIKEN cDNA A630010A05 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 545280
Prl7a1
Name: prolactin family 7, subfamily a, member 1
Synonyms: PLP-G, Prlpe, PLP-E, Prlpg
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19113
Homologene: 136279
Ly6e
Name: lymphocyte antigen 6 family member E
Synonyms: Tsa1, 9804, RIG-E, Ly67, TSA-1, Sca-2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17069
HGNC: HGNC:6727
Homologene: 56411
Acsm4
Name: acyl-CoA synthetase medium-chain family member 4
Synonyms: OMACS, O-MACS
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233801
Homologene: 72281
Or4b1d
Name: olfactory receptor family 4 subfamily B member 1D
Synonyms: MTPCR05, MOR227-7P, Olfr32, GA_x6K02T2Q125-51573576-51572650, MOR227-9_p
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18331
HGNC: HGNC:8290
Homologene: 110550
Fuom
Name: fucose mutarotase
Synonyms: 1810014F10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69064
Homologene: 19598
Trim68
Name: tripartite motif-containing 68
Synonyms: Rnf137, SS-56, F730114J12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101700
Homologene: 9991
Msantd5
Name: Myb/SANT DNA binding domain containing 5
Synonyms: Gm12569
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 622699
Homologene: 141209
Tcstv1b
Name: 2 cell stage variable group member 1B
Synonyms: Gm21818
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 102640804
VEGA: 13
D330020A13Rik
Name: RIKEN cDNA D330020A13 gene
Synonyms: ENSMUSG00000053059
Type: Gene
Species: Mouse
Chromosome: 6
Gm14444
Name: predicted gene 14444
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 105244402
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 8,782,800 bp
  • A to G, chromosome 1 at 34,721,804 bp
  • A to T, chromosome 1 at 75,427,166 bp
  • A to C, chromosome 1 at 105,657,676 bp
  • T to C, chromosome 1 at 150,664,892 bp
  • T to C, chromosome 2 at 90,138,492 bp
  • A to G, chromosome 2 at 157,116,495 bp
  • A to T, chromosome 2 at 175,016,731 bp
  • A to T, chromosome 3 at 38,949,439 bp
  • A to T, chromosome 3 at 41,082,980 bp
  • A to G, chromosome 3 at 69,037,807 bp
  • T to C, chromosome 3 at 144,730,818 bp
  • T to C, chromosome 4 at 58,828,593 bp
  • A to T, chromosome 5 at 25,299,816 bp
  • T to C, chromosome 5 at 89,861,429 bp
  • A to T, chromosome 5 at 109,286,351 bp
  • A to G, chromosome 6 at 38,329,221 bp
  • T to C, chromosome 6 at 120,294,858 bp
  • A to G, chromosome 6 at 124,519,415 bp
  • T to C, chromosome 7 at 85,234,514 bp
  • T to A, chromosome 7 at 85,559,380 bp
  • A to T, chromosome 7 at 102,678,797 bp
  • G to A, chromosome 7 at 119,694,666 bp
  • T to A, chromosome 7 at 140,099,579 bp
  • T to C, chromosome 8 at 104,832,753 bp
  • A to T, chromosome 8 at 105,315,533 bp
  • A to G, chromosome 9 at 18,468,697 bp
  • A to C, chromosome 9 at 39,572,549 bp
  • A to G, chromosome 9 at 44,684,718 bp
  • A to G, chromosome 9 at 51,008,832 bp
  • A to G, chromosome 9 at 106,198,696 bp
  • G to A, chromosome 9 at 110,514,614 bp
  • G to A, chromosome 11 at 51,234,786 bp
  • A to T, chromosome 13 at 27,633,678 bp
  • A to T, chromosome 13 at 44,922,289 bp
  • T to C, chromosome 13 at 93,096,357 bp
  • C to T, chromosome 13 at 113,319,606 bp
  • G to T, chromosome 13 at 120,173,159 bp
  • G to A, chromosome 14 at 14,773,348 bp
  • A to T, chromosome 14 at 88,467,431 bp
  • T to A, chromosome 15 at 74,957,851 bp
  • A to G, chromosome 16 at 14,618,485 bp
  • G to C, chromosome 16 at 34,879,524 bp
  • G to T, chromosome 17 at 57,080,880 bp
  • G to A, chromosome 18 at 6,212,517 bp
  • G to A, chromosome 18 at 65,464,116 bp
  • T to C, chromosome 18 at 65,737,847 bp
  • C to T, chromosome 19 at 12,862,479 bp
  • T to A, chromosome 19 at 13,445,298 bp
  • T to C, chromosome 19 at 24,360,093 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7892 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045944-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.